Administration of Anesthesia in a Patient with Allgrove Syndrome

The aim of the present paper is to report the anesthesia administration to a patient who was planned to undergo Heller myotomy for achalasia. There wasnot property in the patient whom allgrove syndrome was excepted any steroid treatment in preoperative period. The night before the operation 18 mg of prednisolone was administered intravenously. Induction of anesthesia was performed with thiopental sodium, vecuronium and fentanyl and the patient received endotracheal intubation. Eyes were taped closed and protected with ointment during surgery. Maintenance of anesthesia was achieved with 2% sevoflurane concentration in 50% O2-50% N2O. 25 mg of prednisolone was infused preoperatively, and intervention with insulin treatment was initiated when blood glucose level rose to 18 mmol/L at 2 hours. Safe anesthesia can be achieved by observing the preoperative development of tracheal aspiration, adrenal insufficiency and, autonomic dysfunction carefully and maintaining eye protection

Monitoring of drinking water distribution system by SCADA in Antalya City, Turkey

Antalya water and wastewater administration has recently completed SCADA (Supervisory Control And Data Acquisition) system. The system enabled the on-line continuous monitoring of many water quantity and quality parameters such as flow rate, pressure, temperature, pH, turbidity, electrical conductivity, and free residual chlorine. Additionally, water levels in the distribution reservoirs, water pumps, energy consumption and the closing valves are monitored and controlled by the SCADA system. Beside the on-line continuous monitoring, field sampling and lab analyses of other water quality parameters such as total organic carbon, THM, bromide, iron, nitrogen and phosphorous groups, and coliform bacteria were conducted. The results of field sampling agreed with the on-line monitoring values. The SCADA system proved to be very useful for reducing water losses, improving water quality, reducing energy consumption and improving the reliability of the system

Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6: A Preliminary Report from Istanbul

Rad ne sadrži sažetak

Characterization of greater middle eastern genetic variation for enhanced disease gene discovery

The Greater Middle East (GME) has been a central hub of human migration and population admixture. The tradition of consanguinity, variably practiced in the Persian Gulf region, North Africa, and Central Asia1-3, has resulted in an elevated burden of recessive disease4. Here we generated a whole-exome GME variome from 1,111 unrelated subjects. We detected substantial diversity and admixture in continental and subregional populations, corresponding to several ancient founder populations with little evidence of bottlenecks. Measured consanguinity rates were an order of magnitude above those in other sampled populations, and the GME population exhibited an increased burden of runs of homozygosity (ROHs) but showed no evidence for reduced burden of deleterious variation due to classically theorized ‘genetic purging’. Applying this database to unsolved recessive conditions in the GME population reduced the number of potential disease-causing variants by four- to sevenfold. These results show variegated genetic architecture in GME populations and support future human genetic discoveries in Mendelian and population genetics

Abrasion Prediction at Kayraktepe Sediment Bypass Tunnel in Turkey

Sediment accumulation in reservoirs is a challenging issue that concerns most of the reservoirs worldwide. Use of sediment bypass tunnels is one of the potential solutions to reduce sediments deposited in reservoirs. However, the sediment bypass tunnels could face major invert abrasion problems due to intense bedload sediment transportation. Three existing abrasion prediction models are introduced developed respectively by Ishibashi (1983), Sklar and Dietrich (2004), and Auel et al. (2015). Those models are applied to estimate the abrasion of the Kayraktepe sediment bypass tunnels in Turkey. The Ishibashi (1983) model results reveal some discrepancies when compared to laboratory data, which reflects that its grinding stress term gives much higher values than its particle impact term does. However, when examining the effect of particle impact term by neglecting the grinding stress, the model predicts consistent results. The model by Auel at al. (2015) demonstrates reasonable predictions in case of regulated abrasion coefficient values are used. The model of Sklar and Dietrich (2004) predicts the lowest abrasion value due to its development according to the subcritical flow conditions. In Kayraktepe dam, the flow condition in sediment bypass tunnels are supercritical flow, thus the Sklar and Dietrich (2004) model does not fit for abrasion estimation. Modifications are made to the Sklar and Dietrich (2004) model are the revised model shows great improvement on the abrasion prediction. It is concluded that the estimation of sediment transport rate using commonly adapted theoretical or empirical formulations tends to be predicted more than the real transport rate and results in the over-estimation of the abrasion rate. It is recommended to modify the formulations and equation coefficients with the inputs of the field data on laboratory measurements for bettering the abrasion prediction.Civil and Environmental Engineering, Department o

The Effect of Smoking on Functional Parameters of Healthy Individuals

Worldwide, smoking is one of the preventable causes of death. It is a persistent health problem in Turkey and 43.5% of adult population is smoking. The aim was to study the effects of smoking on pulmonary function test, exercise capacity, dyspnea index and life quality. 139 cases, 83.5% of whom were men with mean age of 62 were evaluated; 36 cases (25.9%) were nonsmokers, 46 (33.1%) were smokers and 57 (41.0%) were ex-smokers. Spirometric measurements of smokers were found lower than that of both nonsmokers and ex-smokers. 6MWT distance, dyspnea index and oxygen saturation did not differentiate among nonsmokers, smokers and ex-smokers. Physical component score of SF36 life quality was not associated with smoking. Only mental component score of smokers was found lower than that of ex-smokers. 6MWT distance, dyspnea index, SpO(2) and life quality of cases whose exposure to smoking was = 50 package-year was not different than nonsmokers and cases with = 50 package-year exposure to smoking; however, dyspnea index and SpO2 were found significantly high and significantly low respectively. There were losses in exercise capacity, dyspnea perception and life quality of smokers and these functional losses were associated with the level of exposure to smoking

Ochratoxin A in dried grapes and grape-derived products in Turkey

Ochratoxin A (OTA) is a naturally occurring mycotoxin and widespread food contaminant which results in a probable human exposure. A total of 85 samples (50 dried grapes, 10 grape juices and 25 pekmez (boiled and concentrated grape juices) were collected from different supermarkets and traditional bazaars in Istanbul during 2008-2009. An analytical method based on immuno-affinity column for clean-up and high-performance liquid chromatography equipped with fluorescence detection was used to determine the OTA. Contamination frequencies were 8%, 20% and 88% with mean concentrations of positive samples of 1.15, 1.40 and 2.04 mu g/kg for dried grapes, grape juices and pekmez samples, respectively. These levels were lower than the maximum levels as set by the European Commission (EC). However, 12 of 25 pekmez samples had higher levels than permitted by the European Union (EU) for safe consumption