434 research outputs found

    Comparative study of accounting adaptation: China and Japan during the nineteenth century

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    This study attempts to examine why western accounting was adopted in one Asian country, Japan, and not in another, China, when modern accounting methods were brought to the East during the mid-19th century. The explanation offered is socio-cultural. China was characterized by centralized political power, a society resistant to change, an anti-merchant policy and narrow-based learning. In contrast, Japan had dispersed structures of political power, a society receptive to change, a pro-merchant policy and broad-based learning. In China, the emphasis was to preserve harmony and integration in accord with mainstream Chinese ideology which had created a highly stable and tradition-oriented society. Chinese enterprises that operated within this institutional framework were unlikely to adopt western-style double-entry bookkeeping. In Japan there was no specifically institutionalized anti-capitalist doctrine to prevent the rise of industrialism and the adoption of modern accounting

    Effects of oxytocin on attention to emotional faces in healthy volunteers and highly socially anxious males

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    Background: Evidence suggests that individuals with social anxiety demonstrate vigilance to social threat, whilst the peptide hormone oxytocin is widely accepted as supporting affiliative behaviour in humans. Methods: This study investigated whether oxytocin can affect attentional bias in social anxiety. In a double-blind, randomized, placebo-controlled, within-group study design, 26 healthy and 16 highly socially anxious (HSA) male volunteers (within the HSA group, 10 were diagnosed with generalized social anxiety disorder) were administered 24 IU of oxytocin or placebo to investigate attentional processing in social anxiety. Attentional bias was assessed using the dot-probe paradigm with angry, fearful, happy and neutral face stimuli. Results: In the baseline placebo condition, the HSA group showed greater attentional bias for emotional faces than healthy individuals. Oxytocin reduced the difference between HSA and non-socially anxious individuals in attentional bias for emotional faces. Moreover, it appeared to normalize attentional bias in HSA individuals to levels seen in the healthy population in the baseline condition. The biological mechanisms by which oxytocin may be exerting these effects are discussed. Conclusions: These results, coupled with previous research, could indicate a potential therapeutic use of this hormone in treatment for social anxiety

    Optimization and Functional Effects of Stable Short Hairpin RNA Expression in Primary Human Lymphocytes via Lentiviral Vectors

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    Specific, potent, and sustained short hairpin RNA (shRNA)-mediated gene silencing is crucial for the successful application of RNA interference technology to therapeutic interventions. We examined the effects of shRNA expression in primary human lymphocytes (PBLs) using lentiviral vectors bearing different RNA polymerase III promoters. We found that the U6 promoter is more efficient than the H1 promoter for shRNA expression and for reducing expression of CCR5 in PBLs. However, shRNA expression from the U6 promoter resulted in a gradual decline of the transduced cell populations. With one CCR5 shRNA this decline could be attributed to elevated apoptosis but another CCR5 shRNA that caused cytotoxicity did not show evidence of apoptosis, suggesting sequence-specific mechanisms for cytotoxicity. In contrast to the U6 promoter, PBLs transduced by vectors expressing shRNAs from the H1 promoter could be maintained without major cytotoxic effects. Since a lower level of shRNA expression appears to be advantageous to maintaining the shRNA-transduced population, lentiviral vectors bearing the H1 promoter are more suitable for stable transduction and expression of shRNA in primary human T lymphocytes. Our results suggest that functional shRNA screens should include tests for both potency and adverse metabolic effects upon primary cells

    Continuous backward-wave generation by degenerate four-wave mixing in optical fibers

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    We report on the observation of cw backward-wave generation using degenerate four-wave mixing in a nonresonant medium. The interaction took place inside a 3-m-long CS2-filled 4-µm i.d. optical fiber. With a pump power of only 6 mW inside the fiber, a backward-wave conversion efficiency of 0.45% has been observed, which is in reasonable agreement with theoretical predictions

    Analytical model for residual bond strength of corroded reinforcement in concrete structures

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    Bond strength deterioration in corrosion-damaged reinforced concrete structures significantly affects serviceability and load-carrying capacity in their remaining service life. This paper presents a new analytical model for predicting the cracking development in the surrounding concrete and the residual bond strength of rebar in concrete structures due to reinforcement corrosion. The proposed analytical method adopts the thick-walled cylinder model for the cover concrete and considers the realistic properties of the corrosion-induced cracked concrete such as anisotropic behavior, residual tensile strength, and reduced tensile stiffness. As corrosion progresses, three phases for bond strength evolution associated with concrete cracking development are defined and the corresponding corrosion levels in each phase are determined. By using the constructed new governing equation, the crack width growth in the concrete cover and the radial bursting pressure at the bond interface are evaluated. The ultimate bond strength is then estimated from the contributions of adhesion, confinement, and corrosion pressure as a function of corrosion level. Finally, the effectiveness of the proposed analytical model is demonstrated by comparing the predicted results with experimental data available, and the results show that the proposed model is useful for predicting the bond strength evolution of the corroded rebar in concrete structures

    Do adults with high functioning autism or Asperger Syndrome differ in empathy and emotion recognition?

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    The present study examined whether adults with high functioning autism (HFA) showed greater difficulties in (i) their self-reported ability to empathise with others and/or (ii) their ability to read mental states in others’ eyes than adults with Asperger syndrome (AS). The Empathy Quotient (EQ) and ‘Reading the Mind in the Eyes’ Test (Eyes Test) were compared in 43 adults with AS and 43 adults with HFA. No significant difference was observed on EQ score between groups, while adults with AS performed significantly better on the Eyes Test than those with HFA. This suggests that adults with HFA may need more support, particularly in mentalizing and complex emotion recognition, and raises questions about the existence of subgroups within autism spectrum conditions
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