231 research outputs found

    Morpho/Proteomic Comparative between High Grade Pleomorphic Sarcoma and Metastasis Diagnosed in an Old Captive Common Hippo

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    Old age is a risk factor for cancer development in humans and animals, and studies have shown that tumors in animals are acceptable models for studying human cancers, considering the similarities between their factors. This work was conducted in a 53-year-old captive female common hippo (Hippopotamus amphibious) with a left leg tumor and metastatic mass. Histopathological and immunohistochemical analyses were carried out with a final diagnosis of a high grade pleomorphic sarcoma. A proteomic study using mass spectrometry was added in order to identify further aspects of the primary tumor and metastasis which could improve our understanding, and each tissue showed a proteomic profile indicative of its pathologic state with significant differences between healthy tissue, primary and metastatic tumors. Low levels of beta-actin in primary tumors were identified, and this may be associated with a possible consequence of cytoskeleton dynamic modification. In metastatic tissue, these dynamics may be affected by the presence of HSP chaperone 60.FAPESP: 2012/02514-9Univ Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, BR-04039032 Diadema, SP, BrazilUniv Fed Sao Paulo, Escola Paulista Med, BR-04023062 Sao Paulo, SP, BrazilAC Camargo Canc Ctr, Dept Patol, BR-01509010 Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, BR-04039032 Diadema, SP, BrazilUniv Fed Sao Paulo, Escola Paulista Med, BR-04023062 Sao Paulo, SP, BrazilWeb of Scienc

    Controle biológico de alguns fitopatógenos do solo no tomateiro.

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    Objetivando avaliar o comportamento do antagônico trichoderma spp. à Fusarium oxysporum, Sclerotium rolfsii e Rhizoctonia solani, "in vitro" no laboratório do EMBRAPA/CPATSA

    Cross sections relevant to gamma-ray line emission in solar flares:3^3He-induced reactions on 16^{16}O nuclei

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    Gamma-ray production cross sections have been measured for gamma-ray lines copiously emitted in the 3^3He bombardment of 16^{16}O nuclei: the 937, 1042 and 1081 keV lines of 18^{18}F and the 1887 keV line of 18^{18}Ne. Four Ge detectors with BGO shielding for Compton suppression were used to measure the angular distributions of the gamma-rays. The excitation functions have been obtained for 3^3He bombarding energies from 3.7 to 36 MeV. Total cross sections are tabulated for calculations relevant to gamma-ray astronomy. The importance of these lines as diagnosis for the presence and properties of accelerated 3^3He in solar flares is discussed in light of the measured cross sections.Comment: Phys. Rev. C68 (2003) 0258XX, in pres

    A new experiment for the determination of the 18F(p,alpha) reaction rate at nova temperatures

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    The 18F(p,alpha) reaction was recognized as one of the most important for gamma ray astronomy in novae as it governs the early 511 keV emission. However, its rate remains largely uncertain at nova temperatures. A direct measurement of the cross section over the full range of nova energies is impossible because of its vanishing value at low energy and of the short 18F lifetime. Therefore, in order to better constrain this reaction rate, we have performed an indirect experiment taking advantage of the availability of a high purity and intense radioactive 18F beam at the Louvain La Neuve RIB facility. We present here the first results of the data analysis and discuss the consequences.Comment: Contribution to the Classical Novae Explosions conference, Sitges, Spain, 20-24 May 2002, 5 pages, 3 figure

    Efeitos do anelamento como retardante de crescimento em Botryodiplodia theobromae-II.

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    Foi observado que a prática do anelamento pode ser adotada desde que a proteção dos ferimentos seja de imediato e periódicamente

    Botryodiplodia theobromae Lat. em mangueira do vale Sao Francisco, IV.Protecao de pomares.

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    Este trabalho objetivou definir um manejo efetivo de proteção para que este venha a ser incluído num cronograma de rotina anual e adotados por todos os mangicultores da região.Suplemento
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