Impact of Spirituality on Stress: With the Special Reference of Engineering Students of Indian Institute of Technology

Spirituality is to ‘know’ who you are and the knowledge of yourself understanding the highest spiritual qualities and attributes which are love, peace, purity and bliss. Spirituality is a resilient and controversial variable that has evidenced an ability to help people better cope with stress.  This empirical research paper attempts to identify the relation between spirituality and stress in the student life. In student life, meaning of the spirituality is different and beyond from the prayer, religion, etc., this paper covered the factors which affect the students and engender the stress.  Four types of indicators are used for measurement of stress such as behavioural indicators, emotional indicator, sleep indicator and personal habits of students. Hypothesis said there is no relation between spirituality, stress and academic life of students. Spirituality is high then stress will be low or if spirituality is low then stress will be high. Data is collected through the questionnaire based on spirituality index and stress index. 75 students have taken as participants to find out the level of spirituality and stress in scale and correlation is used for determine the relation between spirituality and stress. The result showed that there is negative correlation (r = -0.519) between the stress and spirituality of engineering students. Stress indicators showed that emotional indicators and physical indicators are high in girls than boys. Keywords: Spirituality, faith, stress, supreme power, engineering students

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Study of microvascular blood flow modulated by electroosmosis

An analytical study of microvascular non-Newtonian blood flow is conducted incorporating the electro-osmosis phenomenon. Blood is considered as a Bingham rheological aqueous ionic solution. An externally applied static axial electrical field is imposed on the system. The Poisson-Boltzmann equation for electrical potential distribution is implemented to accommodate the electrical double layer (EDL) in the microvascular regime. With long wavelength, lubrication and Debye-Hückel approximations, the boundary value problem is rendered non-dimensional. Analytical solutions are derived for the axial velocity, volumetric flow rate, pressure gradient, volumetric flow rate, averaged volumetric flow rate along one time-period, pressure rise along one wavelength and stream function. A plug width is featured in the solutions. Via symbolic software (MathematicaTM), graphical plots are generated for the influence of Bingham plug flow width parameter, electrical Debye length (thickness) and Helmholtz-Smoluchowski velocity (maximum electro-osmotic velocity) on the key hydrodynamic variables. An increase in plug flow width is observed to accelerate the axial flow, enhance volumetric flow rate and has a varied influence on the pressure rise depending on whether the flow is in the free pumping or pumping region. Increasing electrical Debye length consistently enhances axial flow, volumetric flow rate and also pressure rise (at any value of volumetric flow rate)

High-resolution CT phenotypes in pulmonary sarcoidosis: a multinational Delphi consensus study

One view of sarcoidosis is that the term covers many different diseases. However, no classification framework exists for the future exploration of pathogenetic pathways, genetic or trigger predilections, patterns of lung function impairment, or treatment separations, or for the development of diagnostic algorithms or relevant outcome measures. We aimed to establish agreement on high-resolution CT (HRCT) phenotypic separations in sarcoidosis to anchor future CT research through a multinational two-round Delphi consensus process. Delphi participants included members of the Fleischner Society and the World Association of Sarcoidosis and other Granulomatous Disorders, as well as members' nominees. 146 individuals (98 chest physicians, 48 thoracic radiologists) from 28 countries took part, 144 of whom completed both Delphi rounds. After rating of 35 Delphi statements on a five-point Likert scale, consensus was achieved for 22 (63%) statements. There was 97% agreement on the existence of distinct HRCT phenotypes, with seven HRCT phenotypes that were categorised by participants as non-fibrotic or likely to be fibrotic. The international consensus reached in this Delphi exercise justifies the formulation of a CT classification as a basis for the possible definition of separate diseases. Further refinement of phenotypes with rapidly achievable CT studies is now needed to underpin the development of a formal classification of sarcoidosis

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

Background Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We aimed to assess the effects of early administration of tranexamic acid on death, hysterectomy, and other relevant outcomes in women with post-partum haemorrhage. Methods In this randomised, double-blind, placebo-controlled trial, we recruited women aged 16 years and older with a clinical diagnosis of post-partum haemorrhage after a vaginal birth or caesarean section from 193 hospitals in 21 countries. We randomly assigned women to receive either 1 g intravenous tranexamic acid or matching placebo in addition to usual care. If bleeding continued after 30 min, or stopped and restarted within 24 h of the first dose, a second dose of 1 g of tranexamic acid or placebo could be given. Patients were assigned by selection of a numbered treatment pack from a box containing eight numbered packs that were identical apart from the pack number. Participants, care givers, and those assessing outcomes were masked to allocation. We originally planned to enrol 15 000 women with a composite primary endpoint of death from all-causes or hysterectomy within 42 days of giving birth. However, during the trial it became apparent that the decision to conduct a hysterectomy was often made at the same time as randomisation. Although tranexamic acid could influence the risk of death in these cases, it could not affect the risk of hysterectomy. We therefore increased the sample size from 15 000 to 20 000 women in order to estimate the effect of tranexamic acid on the risk of death from post-partum haemorrhage. All analyses were done on an intention-to-treat basis. This trial is registered with ISRCTN76912190 (Dec 8, 2008); ClinicalTrials.gov, number NCT00872469; and PACTR201007000192283. Findings Between March, 2010, and April, 2016, 20 060 women were enrolled and randomly assigned to receive tranexamic acid (n=10 051) or placebo (n=10 009), of whom 10 036 and 9985, respectively, were included in the analysis. Death due to bleeding was significantly reduced in women given tranexamic acid (155 [1·5%] of 10 036 patients vs 191 [1·9%] of 9985 in the placebo group, risk ratio [RR] 0·81, 95% CI 0·65–1·00; p=0·045), especially in women given treatment within 3 h of giving birth (89 [1·2%] in the tranexamic acid group vs 127 [1·7%] in the placebo group, RR 0·69, 95% CI 0·52–0·91; p=0·008). All other causes of death did not differ significantly by group. Hysterectomy was not reduced with tranexamic acid (358 [3·6%] patients in the tranexamic acid group vs 351 [3·5%] in the placebo group, RR 1·02, 95% CI 0·88–1·07; p=0·84). The composite primary endpoint of death from all causes or hysterectomy was not reduced with tranexamic acid (534 [5·3%] deaths or hysterectomies in the tranexamic acid group vs 546 [5·5%] in the placebo group, RR 0·97, 95% CI 0·87-1·09; p=0·65). Adverse events (including thromboembolic events) did not differ significantly in the tranexamic acid versus placebo group. Interpretation Tranexamic acid reduces death due to bleeding in women with post-partum haemorrhage with no adverse effects. When used as a treatment for postpartum haemorrhage, tranexamic acid should be given as soon as possible after bleeding onset. Funding London School of Hygiene & Tropical Medicine, Pfizer, UK Department of Health, Wellcome Trust, and Bill & Melinda Gates Foundation

The ‘dark bronchus’ sign: HRCT diagnosis of Pneumocystis carinii pneumonia

We report the importance of the ‘dark bronchus’ sign in the diagnosis of uniform, diffuse ground glass opacification on high resolution computerized tomography (HRCT). This sign is useful to identify diffuse ground glass opacity on HRCT in cases of Pneumocystis carinii pneumonia who may present with a normal or equivocal chest radiograph in the early course of disease

The &#x2032;dark bronchus&#x2032; sign: HRCT diagnosis of <i> Pneumocystis carinii </i> pneumonia

We report the importance of the &#x2032;dark bronchus&#x2032; sign in the diagnosis of uniform, diffuse ground glass opacification on high resolution computerized tomography (HRCT). This sign is useful to identify diffuse ground glass opacity on HRCT in cases of <i> Pneumocystis carinii </i> pneumonia who may present with a normal or equivocal chest radiograph in the early course of disease

Peristaltic pumping through porous medium in presence of electric double layer

The present paper investigates the peristaltic flow of Newtonian fluids through the porous medium. The effects of electroosmosis mechanism on peristaltic pumping are also considered. An analytical solution is obtained under lubrication approach. Poisson Boltzmann equations are also simplified using Debye linearization. The effects of permeability parameter, electrical double layer thickness and electro-osmotic parameter on the flow characteristics, pressure distribution and shear stress distributions are computed. Numerical computations reveal that electroosmosis and permeability play vital role in peristaltic pumping. The findings of present study may be applicable in biomedical engineering and chemical engineering where peristaltic micropumps may be designed