155 research outputs found

    Comparative Analysis of Machine Learning Techniques for Predicting Air Pollution

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    The modern and motorized way of life has cultured air pollution.  Air pollution has become the biggest rival of robust living. This situation is becoming more lethal in developing countries and so in Pakistan.  Hence, this inquiry was carried out to propose an architecture design that could make real-time prediction of air pollution with another purpose of scanning the frequently adopted algorithm in past investigations. In addition, it was also intended to narrate the toxic effects of air pollution on human health. So, this research was carried out on a large dataset of Seoul as an adequate dataset of Pakistan was not attainable. The dataset consisted of three years (2017-2019) including 647,512 instances and 11 attributes. The four distinctive algorithms termed Random Forest, Linear Regression, Decision Tree and XGBoosting were employed. It was inferred that XGB is more promising and feasible in predicting concentration level of NO2, O3, SO2, PM10, PM2.5 and CO with the lowest RMSE and MAE values of 0.0111, 0.0262, 0.0168, 49.64, 41.68 and 0.1856 and 0.0067, 0.0096, 0.0017, 12.28, 7.63 and 0.0982 respectively. Furthermore, it was found out as well that the Random Forest was preferred mostly in the previous studies related to air pollution prophecy while many probes supported that air pollution is very detrimental to human health especially long-lasting exposure causes lung cancer, respiratory and cardiovascular diseases

    Evaluation of erectile dysfunction with color Doppler sonography

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    Objective: To assess the role of Color Doppler Sonography in the evaluation of erectile dysfunction.Methods: A cross-sectional study was conducted at the Radiology Department, Aga Khan University Hospital Karachi from 5-6-2002 to 2-9-2003. All consecutive patients presenting with erectile dysfunction and undergoing penile color Doppler evaluation with injection PGE1 20 mcg were included in this study.Results: A total of 70 patients with an age range of 24-70 years (mean 41 +/- 12.25 years) were included in the study. A normal response was noted in 45 (psychogenic) cases. Vasculogenic causes were observed in 23 patients, 12 with arterial insufficiency and 11 with venous leak. Peyronie\u27s disease was diagnosed in 2 patients.CONCLUSION: Color Doppler evaluation of erectile dysfunction is an effective method for differentiating psychogenic and vasculogenic causes of erectile dysfunction

    Efficacy of mannan-oligosaccharide and live yeast feed additives on performance, rumen morphology, serum biochemical parameters and muscle morphometric characteristics in buffalo calves

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    The objective of the current study was to assess the effect of dietary supplementations of mannan-oligosaccharide, live yeast, and a combination of these two additives on growth performance, histo-morphology of the rumen, and muscle morphometric attributes in buffalo calves. A total of twenty buffalo calves (average weight of 25 kg) having 3 months of age were distributed according to a complete randomized design. All animals were individually stalled in the shed and were fed ad-libitum. Experimental animals were divided into four groups for 67 days: Control group(without the inclusion of dietary supplementation); MOS group (Mannan oligosaccharide 5 g/clave/day; Yeast group (Live yeast 2g/calve/day) and Mixed group (MOS + Live Yeast 2.5g + 1g )/calve/day. Experimental results revealed that combined supplementation of MOS and Yeast and MOS alone resulted in an increased number of short-chain fatty acids in the rumen as well as ruminal pH (P<0.05). Results showed a significant improvement in average daily gain and FCR of MOS and Mixed supplemented groups (P<0.05). Histomorphological evaluation of rumen mucosal epithelium showed a significant improvement in the mixed-supplemented group (P<0.05) as compared to the yeast-supplemented and control groups. Muscle quality parameters such as meat texture showed significant improvement in MOS and mix-supplemented groups. Histological examination of longissimus dorsi muscle cross-section showed a significantly higher(P<0.05) muscle fiber and muscle fascicle diameter in both MOS and mix-supplemented calves groups. In conclusion, the results of this experiment revealed that the dietary addition of MOS, Live yeast, and their combination have positive effects on growth performance, rumen histology indices, and muscle morphometric features in buffalo calves.Comment: Pages 13, 4 figure

    Influence of β-galacto-oligosaccharide on growth performance and components of intestinal barrier in broilers during heat stress

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    This study aimed to investigate the influence of β-galacto-oligosaccharides (β-GOS) on growth performance, organ development and intestinal microarchitecture of broilers during heat stress. Day-old chicks (n = 125) were divided into five groups. The control or thermoneutral zone group (TNZ) was raised under standard management until the 35th day. Four groups were exposed to cyclic heat stress (35 °C 8 h/d) from the 22nd to the 35th day. The TNZ and heat stress control (HSCT) groups were fed a corn-based diet and HS + 0.1% β-GOS; HS + 0.2% β-GOS; and HS + 0.5% β-GOS were fed a corn-based diet supplemented with β-GOS (0.1%, 0.2%, and 0.5%), respectively. Exposure to heat stress reduced feed consumption, feed efficiency and the relative weight of the liver, bursa of Fabricius, and small intestine, compared with the TNZ group. Morphometric evaluation of the small intestine revealed reduced villus surface area, villus height to crypt depth ratio (VH : CD) and intraepithelial lymphocytes (IELs) in all segments, and reduced acidic goblet cells (AGCs) in the ileum of the HSCT group compared with the TNZ group. Compared with the HSCT group, dietary β-GOS (0.2% and 0.5%) improved the feed efficiency and relative weight of the small intestine. Furthermore, dietary β-GOS (0.1%) increased villus surface area in the duodenum and IEL count in the small intestine compared with the HSCT group. Dietary β-GOS 0.5% increased villi surface area (VSA) in the jejunum and ileum, whereas the IEL count in the small intestine and acidic goblet cells (AGCs) in the jejunum and ileum were reduced compared with the HSCT group. In conclusion, dietary supplementation of β-GOS (0.2% and 0.5%) improved the growth performance and intestinal microarchitecture of broilers during heat exposure, along with partial immune stimulation. Keywords: Feed efficiency, goblet cell, intraepithelial lymphocytes, mucosal architecture, prebiotics, poultry, villus morphometr

    Electrochemical Insight into the Use of Microbial Fuel Cells for Bioelectricity Generation and Wastewater Treatment

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    Microbial fuel cell (MFC) technology is anticipated to be a practical alternative to the activated sludge technique for treating domestic and industrial effluents. The relevant literature mainly focuses on developing the systems and materials for maximum power output, whereas understanding the fundamental electrochemical characteristics is inadequate. This experimental study uses a double-chamber MFC having graphite electrodes and an anion-exchange membrane to investigate the electrochemical process limitations and the potential of bioelectricity generation and dairy effluent treatment. The results revealed an 81% reduction in the chemical oxygen demand (COD) in 10 days of cell operation, with an initial COD loading of 4520 mg/L. The third day recorded the highest open circuit voltage of 396 mV, and the maximum power density of 36.39 mW/m2 was achieved at a current density of 0.30 A/m2. The electrochemical impedance spectroscopy analysis disclosed that the activation polarization of the aerated cathode was the primary factor causing the cell’s resistance, followed by the ohmic and anodic activation overpotentials

    AI-driven optimization of ethanol-powered internal combustion engines in alignment with multiple SDGs: A sustainable energy transition

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    With the escalating requirement for global sustainable energy solutions and the complexities linked with the complete transition to new technologies, internal combustion engines (ICEs) powered with biofuels like ethanol are gaining significance over time. However, problems linked to the performance and emissions of such ICEs necessitate accurate prediction and optimization. The study employed the integration of artificial neural networks (ANN) and multi-level historical design of response surface methodology (RSM) to address these challenges in alignment with the Sustainable Development Goals (SDGs). A single-cylinder spark ignition (SI) engine powered with ethanol-gasoline blends at different loads and speeds was used to gather data. Among six initially trained ANN models, the most efficient model with a regression coefficient (R2) of 0.9952 (training), 0.98579 (validation), 0.98847 (testing), and 0.99307 (overall) was employed to predict outputs such as brake power, brake specific fuel consumption (BSFC), brake thermal energy (BTE), concentration of carbon dioxide (CO2), carbon monoxide (CO), hydrocarbons (HC), and oxides of nitrogen NOx. Predicted outputs were optimized by incorporating RSM. On implementing optimized conditions, it was observed that BP and BTE increased by 19.9%, and 29.8%, respectively. Additionally, CO, and HC emissions experienced substantial reductions of 28.1%, and 40.6%, respectively. This research can help engine producers and researchers make refined decisions and achieve improved performance and emissions. The study directly supports SDG 7, SDG 9, SDG 12, SDG 13, and SGD 17, which call for achieving affordable, clean energy, sustainable industrialization, responsible consumption, and production, taking action on climate change, and partnership to advance the SDGs as a whole respectively

    Acetone-Gasoline Blend as an Alternative Fuel in SI Engines: A Novel Comparison of Performance, Emission, and Lube Oil Degradation

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    The disproportionate use of petroleum products and stringent exhaust emissions has emphasized the need for alternative green fuels. Although several studies have been conducted to ascertain the performance of acetone-gasoline blends in spark-ignition (SI) engines, limited work has been done to determine the influence of fuel on lubricant oil deterioration. The current study fills the gap through lubricant oil testing by running the engine for 120 h on pure gasoline (G) and gasoline with 10% by volume acetone (A10). Compared to gasoline, A10 produced better results in 11.74 and 12.05% higher brake power (BP) and brake thermal efficiency (BTE), respectively, at a 6.72% lower brake-specific fuel consumption (BSFC). The blended fuel A10 produced 56.54, 33.67, and 50% lower CO, CO2, and HC emissions. However, gasoline remained competitive due to lower oil deterioration than A10. The flash-point and kinematic viscosity, compared to fresh oil, decreased by 19.63 and 27.43% for G and 15.73 and 20.57% for A10, respectively. Similarly, G and A10 showed a decrease in total base number (TBN) by 17.98 and 31.46%, respectively. However, A10 is more detrimental to lubricating oil due to a 12, 5, 15, and 30% increase in metallic particles like aluminum, chromium, copper, and iron, respectively, compared to fresh oil. Performance additives like calcium and phosphorous in lubricant oil for A10 decreased by 10.04 and 4.04% in comparison to gasoline, respectively. The concentration of zinc was found to be 18.78% higher in A10 when compared with gasoline. A higher proportion of water molecules and metal particles were found in lubricant oil for A10

    IN VITRO SHOOT REGENERATION FROM COTYLEDON AND HYPOCOTYL EXPLANTS OF DAHLIA CULTIVARS

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    Different exotic dahlia cultivars namely Double Decorative and Double Giant were explored for shoot regeneration using cotyledon leaf and hypocotyl explants on MS medium supplemented with combinations of plant growth regulators (PGRs) viz. NAA and BA (A medium) and BA and IAA (B medium). Callus induction and shoot regeneration was found directly proportional while root formation was inversely proportionate to the addition of PGRs in the media. Maximum response for callus induction (60%) and shoot regeneration (13%) was found in cotyledon leaf and hypocotyl explants, respectively, on medium containing 3 mgL -1 each of NAA and BA. Significant genotypic variation was observed and cultivar Double Giant was found better for callus induction and organogenesis at both media types. Indirect shoot regeneration could be helpful for mass propagation of elite plant material and enhancing diversity in the ornamental plants

    SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs

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    The present study describes the synthesis of a series of 22 chalcone analogs. These compounds were evaluated as potential human MAO-A and MAO-B inhibitors. The compounds showed varied selectivity against the two isoforms. The IC50 values were found to be in the micromolar to submicromolar range. The Ki values of compound 16 were determined to be 0.047 and 0.020 μM for the inhibition of MAO-A and MAO-B, respectively. Dialysis of enzyme-inhibitor mixtures indicated a reversible competitive mode of inhibition. Most of the synthesized chalcone analogs showed a better selectivity toward MAO-B. However, introducing of 2,4,6-trimethoxy substituents on ring B shifted the selectivity toward MAO-A. In addition, we investigated the molecular mechanism of MAO-B inhibition by selected chalcone analogs. Our results revealed that these selected chalcone analogs increased dopamine levels in the rat hepatoma (H4IIE) cells and decreased the relative mRNA expression of the MAO-B enzyme.This work was supported by internal grants from the Office of Academic Research, Qatar University, Doha, Qatar under Grants [# QUUG-CPH-15/16–7 and QUUG-CPH-2017–5]. The publication of this article was funded by the Qatar National Library, Doha, Qatar. The experiments dealing with the testing of the compounds in vitro were supported by the National Institutes on Alcohol Abuse and Alcoholism under Grant Number R01AA019458 (Y.S.). We are grateful to Professor Neal Castagnoli Jr. Professor Emeritus, Virginia Tech for providing the MMTP substrate. The biological section of this study was funded in part by the National Research Foundation of South Africa under Grant [number (UID) 85642, 96180]. The Grantholders acknowledge that opinions, findings and conclusions or recommendations expressed in any publication generated by the NRF supported research are that of the authors and that the NRF accepts no liability whatsoever in this regard.Scopu
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