Minimally Invasive Urological Interventions in Outpatient Clinic on the Example of Prostate Biopsy

One of the main directions of improving medical care was the introduction of inpatient forms of medical care for patients who do not require round-the-clock supervision.Aim of the research: to prove the effectiveness and economic feasibility of minimally invasive procedures in outpatient conditions.Materials and methods. The study included 3524 patients in the period from 2010 to 2017, who underwent transrectal prostate biopsy on the basis of the Department of urology of polyclinic No. 195 of the Western district of Moscow. For comparison, the patients were taken, who underwent a biopsy of the prostate gland at the base hospital No. 31, No. 51, No. 17.Results. The average number of biopsies performed in hospital No. 31, No. 51 and No. 17 for the year amounted to 344 biopsies, and the average detectability of prostate cancer was 142 (41.3 %). The average number of biopsies per year in the urology department of the branch number 2 GP No. 195 amounted to 440.5, and the average detectability of prostate cancer – 152.8 (34.7 %). Thus, with comparable inpatient detection of prostate cancer in one large outpatient urology center, an average of 28 % more biopsies are performed (440.5 versus 344) than in 3 hospitals over a comparable period of time.Conclusions. Inpatient technologies can reduce the burden on hospitals. The development of hospital-replacing forms is determined by the need of the population and for efficient use of financial and technical resources of health care

AUTOMATING THE PROCESS OF PREPARING THE SCHOOL TIMETABLE

This paper presents a development that optimizes the process of educational scheduling by creating algorithms that automatically distribute the load of the educational process and take into account all the preferences of teachers. One of the currently popular platforms for deploying these developments is the google tables platform for creating google tables and creating code based on google app script. The peculiarity of the system implemented with the help of this platform is the ease of use and minimization of resources spent on software storage, which greatly simplifies interaction with the system. Purpose – create a tool for drawing up a study schedule, interacting with a database created in Google Tables, interacting with participants of an educational institution online, which saves personal time of teachers and employees of the dean’s office. Method or methodology of the work: the article discusses a way to optimize the creation of a weekly schedule, taking into account the convenience of the teacher in the distribution of pairs and taking into account the load of the educational process by creating algorithms based on Google app script. For implementation, online tables are used that are accessible to all teachers and employees of the dean’s office, updated in real time, Tables created in Google and the google app script programming language. Result: a unique tool has been developed that implements the functions of adding, storing, interacting and round-the-clock access to training schedule data. Scope of application of the results: the curriculum, stored in online tables and updated by the dean’s office staff, should be used for monitoring by each teacher, keeping track of their time of couples in educational institutions

Thiophenyl-substituted triazolyl-thione l-alanine: asymmetric synthesis, aggregation and biological properties

In this work, we report the asymmetric synthesis and characterization of an artificial amino acid based on triazolyl-thione L-alanine, which was modified with a thiophenyl-substituted moiety, as well as in vitro studies of its nucleic acid-binding ability. We found, by dynamic light scattering studies, that the synthetic amino acid was able to form supramolecular aggregates having a hydrodynamic diameter higher than 200 nm. Furthermore, we demonstrated, by UV and CD experiments, that the heteroaromatic amino acid, whose enzymatic stability was demonstrated by HPLC analysis also after 24 h of incubation in human serum, was able to bind a RNA complex, which is a feature of biomedical interest in view of innovative antiviral strategies based on modulation of RNA-RNA molecular recognition

Ararat1: a new Middle Palaeolithic cave in Ararat Depression, Armenia.

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Thin-film solar cells on perlite glass-ceramic substrates

For the first time, thin-film CIGS solar cells have been fabricated by co-evaporation on specially developed non-conducting perlite (an aluminum potassium sodium silicate natural mineral of volcanic origin) glass-ceramic substrates to develop a fully integrated photovoltaic and building element. Such glass-ceramic material can meet the physical requirements to solar cells substrates as well as the cost goals. The preliminary data presented show that CIGS solar cells deposited on ceramic substrates can exhibit efficiency higher than 10%

Developing a framework for Pleistocene hominin occupations, lake level change and landscape dynamics in the Ararat Depression, Southern Caucasus.

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