Andinismo: desafío para la prensa nacional

Tesis (Periodista)La montaña no perdona. Todo accidente es gatillado por el hombre, no por la montaña o por el clima como erróneamente se cree. Cualquier error puede significar la diferencia entre la vida y la muerte, sin embargo, no siempre se tiene en cuenta este factor. Todos en alguna etapa de nuestras vidas hemos tenido una aproximación a la montaña. Durante una excursión cuando niños, al caminar por un sendero al interior de un parque en vacaciones, ¿pero se toma conciencia de los riesgos que se corren si no se tiene conocimiento de las normas mínimas de seguridad? Terrenos escarpados, sequedad ambiental. Fuerte oscilación térmica, viento, son sólo algunos de los factores característicos de los terrenos cordilleranos. No es necesario subir el Aconcagua para tener un accidente. El mayor número de accidentes, extravíos, fracturas y lesiones derivadas de hipotermia, deshidratación o insolación se da en quienes se aventuran por primera vez en terrenos desconocido con mínima experiencia y precario o nulo equipo. Es habitual leer en la prensa "Andinista extraviado", pero ¿era realmente un andinista o sólo un osado e irresponsable excursionista? Los accidentes más frecuentes se dan en zonas de baja dificultad técnica tales como los senderos de parques nacionales, como la Campana; volcanes, como el Villarrica; cerros cercanos a centros urbanos, como el Provincia, en Santiago. La prensa no hace diferencia entre excursionistas y andinistas, ni se toma el tiempo de profundizar en las causas que provocaron un accidente o extravío. Deja al "cerro" como al malo de la película, obviando la irresponsabilidad de quien es el protagonista y gatillador de este incidente: el hombre. "la montaña se devoró otra andinista", "El clima fue implacable", son sólo algunos de los ejemplos más comunes aparecidos en la prensa nacional, haciendo alusión a accidentes ocurridos en la cordillera. Si se hace un seguimiento de ellos, el 98%1 de ellos corresponden a fallas humanas

Estudos de Cultura Material aplicados à coleção de telegrafia do Museu Correios

Cultural material methods analysis for the study of the Museu Correios telegraphic historical collections of museological objects, to verify its application as a tool for museum documentation and information. The methodology employed was based on documentary analysis, developing a comparison between the models held from pre-established parameters. It was verified that, from the six models studied, none of them is totally applicable to science and technology collections, with necessary changes to its application in this kind of collections and museums, especially to telecommunication museums.Análise de métodos da cultura material para estudo dos objetos museológicos do acervo histórico de telegrafia do Museu Correios, de forma a verificar sua aplicação como ferramenta para a Documentação e Informação em Museus. A metodologia utilizada foi baseada na análise documentária, realizando a comparação entre os modelos a partir de parâmetros pré-estabelecidos. Verificou-se que dos seis modelos estudados, nenhum é totalmente aplicável à coleções de ciência e tecnologia, sendo necessárias adaptações para aplicação no acervo dos museus de ciência e tecnologia, em especial de telecomunicações

Comparación entre dos técnicas de toma de injerto conectivo en cirugía de cobertura radicular.

Objective: To compare root coverage surgery results using subepithelial connective tissue graft (SCGT) and de-epithelialized gingival graft (DGG) in Miller Class I and II gingival recessions. Material and Methods: A review of the literature published in the last 5 years, with articles selected from PubMed and Google Scholar databases, using the search key " de epithelialized gingival graft AND subepithelial connective tissue graft.” Results: A total of 250 articles were obtained. 245 publications were excluded through a manual filter because they were duplicated or did not meet the established criteria, obtaining 5 articles included in this review.  Conclusion: Both harvesting techniques offer satisfactory results of coverage of root recessions. However, there is not enough evidence to state that one technique is superior to the other.Objetivo: Comparar los resultados de la cirugía de cobertura radicular utilizando injerto de tejido conectivo subepitelial (SCGT) e injerto gingival desepitelizado (DGG) en recesiones gingivales clase I y II de Miller. Materiales y métodos: Se realizó una revisión de la literatura de articulos publicados en los últimos 5 años en las bases de datos PubMed y Google Scholar, se utilizó la llave de búsqueda “de epithelialized gingival graft AND subepithelial connective tissue graft”. Resultados: Se obtuvo un total de 250 artículos. De los que, mediante un filtro manual, se excluyeron 245 publicaciones por encontrarse duplicadas o no cumplir con los criterios previamente descritos, obteniéndose, finalmente, 5 artículos incluidos en esta revisión.Conclusión: Ambos procedimientos ofrecen resultados satisfactorios frente a la cobertura de recesiones radiculares. Sin embargo, no existe suficiente evidencia para afirmar que una técnica es superior a la otra

The resolution of acute inflammation induced by cyclic AMP is dependent on annexin A1

Annexin A1 (AnxA1) is a glucocorticoid-regulated protein known for its anti-inflammatory and pro-resolving effects. We have shown previously that the cAMP-enhancing compounds rolipram (ROL; a PDE4 inhibitor) and Bt2cAMP (a cAMP mimetic) drive caspase-dependent resolution of neutrophilic inflammation. In this follow-up study, we investigated whether AnxA1 could be involved in the pro-resolving properties of these compounds using a model of LPS-induced inflammation in BALB/c mice. The treatment with ROL or Bt2cAMP at the peak of inflammation shortened resolution intervals, improved resolution indices, and increased AnxA1 expression. In vitro studies showed that ROL and Bt2cAMP induced AnxA1 expression and phosphorylation, and this effect was prevented by PKA inhibitors, suggesting the involvement of PKA in ROL-induced AnxA1 expression. Akin to these in vitro findings, H89 prevented ROL- and Bt2cAMP-induced resolution of inflammation, and it was associated with decreased levels of intact AnxA1. Moreover, two different strategies to block the AnxA1 pathway (by using N-t-Boc-Met-Leu-Phe, a nonselective AnxA1 receptor antagonist, or by using an anti-AnxA1 neutralizing antiserum) prevented ROL- and Bt2cAMP-induced resolution and neutrophil apoptosis. Likewise, the ability of ROL or Bt2cAMP to induce neutrophil apoptosis was impaired in AnxA-knock-out mice. Finally, in in vitro settings, ROL and Bt2cAMP overrode the survival-inducing effect of LPS in human neutrophils in an AnxA1-dependent manner. Our results show that AnxA1 is at least one of the endogenous determinants mediating the pro-resolving properties of cAMP-elevating agents and cAMP-mimetic drug

Cardiopatía chagásica en la primera región de Chile. Estudio clínico, epidemiológico y parasitológico

705 inhabitants of rural towns in northern Chile were surveyed to study chagasic infection and cardiac involvement. Clinical evaluation, electrocardiogram, indirect hemagglutination test and xenodiagnosis for reactors were employed. Culture of positive xenodiagnosis was done to identify different zymodemes and schizodemes of T cruzi, T spinolai was not found in this area implying the absence of a wild cycle. Triotomines were not found over 3000 m high. Four cases of Z2b T cruzi strains were found. Simultaneous infection by Z1 and Z2b strains was found in the same bug obtained from houses. Overall human infection rate was 10%, and 69% of them showed altered electrocardiograms. Therefore, a lower infection rate but greater evidence of cardiac involvement is found in northern Chile compared to other areas in the country