Patient-reported outcomes of palatal donor site healing using four different wound dressing modalities following free epithelialized mucosal grafts: A four-arm randomized controlled clinical trial

BackgroundThe aim of this study was to compare the effects of four different commonly used wound dressings in improving patient reported outcomes (PROMS) after free epithelialized mucosal grafts (FEGs) harvesting.MethodsFollowing 72 FEGs harvesting from 72 patients, patients were assigned into four groups. Control: collagen plug + sutures (CPS); test: collagen plug with cyano-acrylate (CPC), platelet rich fibrin (PRF) + sutures, or palatal stent only (PS). Patients were observed for 14 days, with evaluation of pain level utilizing the visual analog scale, number of analgesics consumed, need for additional analgesics, amount of swelling, amount of bleeding, activity tolerance, and willingness for retreatment.ResultsCompared to the control group all test groups indicated significant lower pain perception (P  0.05).ConclusionsAll interventions significantly decreased pain perception compared to a hemostatic collagen sponge alone over the palatal donor site after FEG surgery. In the first few days after surgery, the use of a palatal stent seemed to be associated with less overall pain, pain pills consumed, and higher willingness of doing the same procedure again.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/175775/1/jper10994.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/175775/2/jper10994_am.pd