Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine

[This corrects the article DOI: 10.1186/s13054-016-1208-6.]

Hindcast tidal inlet of Ameland storms: January and March 2007

During the storm season from October 2006 untill April 2007 several severe storms occurred at the North Sea. Three storm periods are selected to study the realiability of the SWAN wave model by means of a hindcast. The objective of this hindcast is to gain insight into the performance of the SWAN model, especially under storm conditions for the Hydraulic Boundary Conditions with particular emphasis upon the strengths and weaknesses of the model. The three selected stormperiods (11 and 12 January 2007, 17 and 18 January 2007 and 17 and 18 March 2007) can be described as regular western storms with wind directions varying from the southwest to the northwest and with moderate waterlevels. For these storm periods, measurements from twelve locations using the measurement network at the Tidal inlet of Ameland are used. At the start of this study, the measured wave conditions are validated agian by a consistency check. In order to prevent a selection of spurious measurements for the comparison of measured and modelled waves, all suspicious measurements are excluded from the hindcast selection. The selection of hindcasting moments is based on three different hypotheses. These hypotheses were formulated using the expected behaviour of SWAN during wind growth at shallow water, current conditions and triad interactions. In totally 31 moments are simulated (representing one third of the storms) with the current version of SWAN. The analysis of the differences between the modelled and measured wave parameters and wave spectra shows that for typical Wadden Sea conditions (wind growth over shallow water) SWAN seriously underestimates the significant wave heights. The wave period is well simulated by SWAN. The largest underestimation is observed at the buoy locations at the shallow locations. In the table below the averaged deviation (sigma factor) of SWAN in relation to the measurements is given for different areas.SB

Operations Eclipse Sequencing in Multipurpose Dam Planning

Policy Analysi

Laboratory evolution of a glucose-phosphorylation-deficient, arabinose-fermenting S. cerevisiae strain reveals mutations in GAL2 that enable glucose-insensitive l-arabinose uptake

Cas9-assisted genome editing was used to construct an engineered glucose-phosphorylation-negative S. cerevisiae strain, expressing the Lactobacillus plantaruml-arabinose pathway and the Penicillium chrysogenum transporter PcAraT. This strain, which showed a growth rate of 0.26 h−1 on l-arabinose in aerobic batch cultures, was subsequently evolved for anaerobic growth on l-arabinose in the presence of d-glucose and d-xylose. In four strains isolated from two independent evolution experiments the galactose-transporter gene GAL2 had been duplicated, with all alleles encoding Gal2N376T or Gal2N376I substitutions. In one strain, a single GAL2 allele additionally encoded a Gal2T89I substitution, which was subsequently also detected in the independently evolved strain IMS0010. In 14C-sugar-transport assays, Gal2N376S, Gal2N376T and Gal2N376I substitutions showed a much lower glucose sensitivity of l-arabinose transport and a much higher Km for d-glucose transport than wild-type Gal2. Introduction of the Gal2N376I substitution in a non-evolved strain enabled growth on l-arabinose in the presence of d-glucose. Gal2N376T, T89I and Gal2T89I variants showed a lower Km for l-arabinose and a higher Km for d-glucose than wild-type Gal2, while reverting Gal2N376T, T89I to Gal2N376 in an evolved strain negatively affected anaerobic growth on l-arabinose. This study indicates that optimal conversion of mixed-sugar feedstocks may require complex ‘transporter landscapes’, consisting of sugar transporters with complementary kinetic and regulatory properties.BT/Industrial Microbiolog

Future material requirements for global sustainable offshore wind energy development

Offshore wind energy (OWE) is a cornerstone of future clean energy development. Yet, research into global OWE material demand has generally been limited to few materials and/or low technological resolution. In this study, we assess the primary raw material demand and secondary material supply of global OWE. It includes a wide assortment of materials, including bulk materials, rare earth elements, key metals, and other materials for manufacturing offshore wind turbines and foundations. Our OWE development scenarios consider important drivers such as growing wind turbine size, introducing new technologies, moving further to deep waters, and wind turbine lifetime extension. We show that the exploitation of OWE will require large quantities of raw materials from 2020 to 2040: 129–235 million tonnes (Mt) of steel, 8.2–14.6 Mt of iron, 3.8–25.9 Mt of concrete, 0.5–1.0 Mt of copper and 0.3–0.5 Mt of aluminium. Substantial amounts of rare earth elements will be required towards 2040, with up to 16, 13, 31 and 20 fold expansions in the current Neodymium (Nd), Dysprosium (Dy), Praseodymium (Pr) and Terbium (Tb) demand, respectively. Closed-loop recycling of end-of-life wind turbines could supply a maximum 3% and 12% of total material demand for OWE from 2020 to 2030, and 2030 to 2040, respectively. Moreover, a potential lifetime extension of wind turbines from 20 to 25 years would help to reduce material requirements by 7–10%. This study provides a basis for better understanding future OWE material requirements and, therefore, for optimizing future OWE developments in the ongoing energy transition.Wind EnergyDC systems, Energy conversion & Storag

Naar een kloppend hart: Gebruik en waardering van de buitenruimte in Hart van Zuid

Onderzoek naar het gebruik en de waardering van de buitenruimte in Hart van Zuid. In opdracht van de Gemeente Rotterdam, Projectbureau het Hart van Zuid.UrbanismArchitectur

Description of the multi-approach gravity field models from Swarm GPS data

Although the knowledge of the gravity of the Earth has improved considerably with CHAMP, GRACE, and GOCE (see appendices for a list of abbreviations) satellite missions, the geophysical community has identified the need for the continued monitoring of the time-variable component with the purpose of estimating the hydrological and glaciological yearly cycles and long-term trends. Currently, the GRACE-FO satellites are the sole dedicated provider of these data, while previously the GRACE mission fulfilled that role for 15 years. There is a data gap spanning from July 2017 to May 2018 between the end of the GRACE mission and start the of GRACE-FO, while the Swarm satellites have collected gravimetric data with their GPS receivers since December 2013. We present high-quality gravity field models (GFMs) from Swarm data that constitute an alternative and independent source of gravimetric data, which could help alleviate the consequences of the 10-month gap between GRACE and GRACE-FO, as well as the short gaps in the existing GRACE and GRACE-FO monthly time series. The geodetic community has realized that the combination of different gravity field solutions is superior to any individual model and set up the Combination Service of Time-variable Gravity Fields (COST-G) under the umbrella of the International Gravity Field Service (IGFS), part of the International Association of Geodesy (IAG). We exploit this fact and deliver the highest-quality monthly GFMs, resulting from the combination of four different gravity field estimation approaches. All solutions are unconstrained and estimated independently from month to month. We tested the added value of including kinematic baselines (KBs) in our estimation of GFMs and conclude that there is no significant improvement. The non-gravitational accelerations measured by the accelerometer on board Swarm C were also included in our processing to determine if this would improve the quality of the GFMs, but we observed that is only the case when the amplitude of the non-gravitational accelerations is higher than during the current quiet period in solar activity Using GRACE data for comparison, we demonstrate that the geophysical signal in the Swarm GFMs is largely restricted to spherical harmonic degrees below 12. A 750 km smoothing radius is suitable to retrieve the temporal variations in Earth's gravity field over land areas since mid-2015 with roughly 4 cm equivalent water height (EWH) agreement with respect to GRACE. Over ocean areas, we illustrate that a more intense smoothing with 3000 km radius is necessary to resolve large-scale gravity variations, which agree with GRACE roughly at the level of 1 cm EWH, while at these spatial scales the GRACE observes variations with amplitudes between 0.3 and 1 cm EWH. The agreement with GRACE and GRACE-FO over nine selected large basins under analysis is 0.91 cm, 0.76 cm yr-1, and 0.79 in terms of temporal mean, trend, and correlation coefficient, respectively. The Swarm monthly models are distributed on a quarterly basis at ESA's Earth Swarm Data Access (at https://swarm-diss.eo.esa.int/, last access: 5 June 2020, follow Level2longterm and then EGF) and at the International Centre for Global Earth Models (http://icgem.gfz-potsdam.de/series/02_COST-G/Swarm, last access: 5 June 2020), as well as identified with the DOI https://doi.org/10.5880/ICGEM.2019.006 (Encarnacao et al., 2019). Astrodynamics & Space Mission

Mechanism of assembly of an elongation-competent SARS-CoV-2 replication transcription complex

Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.BN/Martin Depken LabBN/BionanoscienceBN/Nynke Dekker La

The American Egypt : a record of travel in Yucatan /

Includes index.Mode of access: Internet