Low-level accretion in neutron-star X-ray binaries

We search the literature for reports on the spectral properties of neutron-star low-mass X-ray binaries when they have accretion luminosities between 1E34 and 1E36 ergs/s. We found that in this luminosity range the photon index (obtained from fitting a simple absorbed power-law in the 0.5-10 keV range) increases with decreasing 0.5-10 keV X-ray luminosity (i.e., the spectrum softens). Such behaviour has been reported before for individual sources, but here we demonstrate that very likely most (if not all) neutron-star systems behave in a similar manner and possibly even follow a universal relation. When comparing the neutron-star systems with black-hole systems, it is clear that most black-hole binaries have significantly harder spectra at luminosities of 1E34 - 1E35 erg/s. Despite a limited number of data points, there are indications that these spectral differences also extend to the 1E35 - 1E36 erg/s range. This observed difference between the neutron-star binaries and black-hole ones suggests that the spectral properties (between 0.5-10 keV) at 1E34 - 1E35 erg/s can be used to tentatively determine the nature of the accretor in unclassified X-ray binaries. We discuss our results in the context of properties of the accretion flow at low luminosities and we suggest that the observed spectral differences likely arise from the neutron-star surface becoming dominantly visible in the X-ray spectra. We also suggest that both the thermal component and the non-thermal component might be caused by low-level accretion onto the neutron-star surface for luminosities below a few times 1E34 erg/s.Comment: Accepted for publication in MNRA

The optical counterpart of the bright X-ray transient Swift J1745-26

We present a 30-day monitoring campaign of the optical counterpart of the bright X-ray transient Swift J1745-26, starting only 19 minutes after the discovery of the source. We observe the system peaking at i' ~17.6 on day 6 (MJD 56192) to then decay at a rate of ~0.04 mag/day. We show that the optical peak occurs at least 3 days later than the hard X-ray (15-50 keV) flux peak. Our measurements result in an outburst amplitude greater than 4.3 magnitudes, which favours an orbital period < 21 h and a companion star with a spectral type later than ~ A0. Spectroscopic observations taken with the GTC-10.4 m telescope reveal a broad (FWHM ~ 1100 km/s), double-peaked H_alpha emission line from which we constrain the radial velocity semi-amplitude of the donor to be K_2 > 250 km/s. The breadth of the line and the observed optical and X-ray fluxes suggest that Swift J1745-26 is a new black hole candidate located closer than ~7 kpc.Comment: 5 pages, 4 figures, accepted for publication in MNRA

Promoter Variation and Expression Levels of Inflammatory Genes IL1A, IL1B, IL6 and TNF in Blood of Spinocerebellar Ataxia Type 3 (SCA3) Patients

Age at onset in spinocerebellar ataxia type 3 (SCA3/MJD) is incompletely explained by the size of the CAG tract at the ATXN3 gene, implying the existence of genetic modifiers. A role of inflammation in SCA3 has been postulated, involving altered cytokines levels; promoter variants leading to alterations in cytokines expression could influence onset. Using blood from 86 SCA3 patients and 106 controls, this work aimed to analyse promoter variation of four cytokines (IL1A, IL1B, IL6 and TNF) and to investigate the association between variants detected and their transcript levels, evaluated by quantitative PCR. Moreover, the effect of APOE isoforms, known to modulate cytokines, was investigated. Correlations between cytokine variants and onset were tested; the cumulative modifier effects of cytokines and APOE were analysed. Patients carrying the IL6*C allele had a significant earlier onset (4 years in average) than patients carrying the G allele, in agreement with lower mRNA levels produced by IL6*C carriers. The presence of APOE*ɛ2 allele seems to anticipate onset in average 10 years in patients carrying the IL6*C allele; a larger number of patients will be needed to confirm this result. These results highlight the pertinence of conducting further research on the role of cytokines as SCA3 modulators, pointing to the presence of shared mechanisms involving IL6 and APOE

Hβ\beta spectroscopy of the high-inclination black hole transient Swift J1357.2-0933 during quiescence

Swift J1357.2-0933 is a transient low-mass X-ray binary hosting a stellar-mass black hole. The source exhibits optical dips and very broad emission lines during both outburst and quiescence, which are thought to be the result of a high orbital inclination. We present phase-resolved spectroscopy obtained with the 10.4m Gran Telescopio Canarias (GTC). The spectra focus on the $\rm{H}\beta$ spectral region during X-ray quiescence. The emission line is exceptionally broad (full width at half maximum, FWHM > 4000 \AA), in agreement with previous studies focused on $\rm{H}\alpha$. A two-Gaussian fit to the prominent double-peaked profile reveals a periodic variability in the centroid position of the line. We also produced a diagnostic diagram aimed at constraining additional orbital parameters. Together, they allow us to independently confirm the orbital period of the system using a new dataset obtained five years after the previous outburst. However, our estimates for both the systemic velocity and the radial velocity semi-amplitude of the black hole reveal larger values than those found in previous studies. We argue that this could be explained by the precession of the disc and the presence of a hotspot. We found evidence of a narrow inner core in the double-peaked H$\beta$ emission profile. We studied its evolution across the orbit, finding that it is likely to result from the occultation of inner material by the outer rim bulge, further supporting the high orbital inclination hypothesis.Comment: 6 pages, 4 figure

The 1989 and 2015 outbursts of V404 Cygni: a global study of wind-related optical features

The black hole transient V404 Cygni exhibited a bright outburst in June 2015 that was intensively followed over a wide range of wavelengths. Our team obtained high time resolution optical spectroscopy (~90 s), which included a detailed coverage of the most active phase of the event. We present a database consisting of 651 optical spectra obtained during this event, that we combine with 58 spectra gathered during the fainter December 2015 sequel outburst, as well as with 57 spectra from the 1989 event. We previously reported the discovery of wind-related features (P-Cygni and broad-wing line profiles) during both 2015 outbursts. Here, we build diagnostic diagrams that enable us to study the evolution of typical emission line parameters, such as line fluxes and equivalent widths, and develop a technique to systematically detect outflow signatures. We find that these are present throughout the outburst, even at very low optical fluxes, and that both types of outflow features are observed simultaneously in some spectra, confirming the idea of a common origin. We also show that the nebular phases depict loop patterns in many diagnostic diagrams, while P-Cygni profiles are highly variable on time-scales of minutes. The comparison between the three outbursts reveals that the spectra obtained during June and December 2015 share many similarities, while those from 1989 exhibit narrower emission lines and lower wind terminal velocities. The diagnostic diagrams presented in this work have been produced using standard measurement techniques and thus may be applied to other active low-mass X-ray binaries.Comment: Accepted for publication in MNRAS. 23 pages paper, plus a 9 pages appendix with extra tables and figures. 18 figures are included in the paper and 8 in the appendi

Importance of tissue sampling, laboratory methods, and patient characteristics for detection of Pneumocystis in autopsied lungs of non-immunosuppressed individuals

To understand the epidemiological significance of Pneumocystis detection in a lung tissue sample of non-immunosuppressed individuals, we examined sampling procedures, laboratory methodology, and patient characteristics of autopsy series reported in the literature. Number of tissue specimens, DNA-extraction procedures, age and underlying diagnosis highly influence yield and are critical to understand yield differences of Pneumocystis among reports of pulmonary colonization in immunocompetent individuals.publishersversionpublishe

Soft-state optical spectroscopy of the black hole MAXI J1305-704

The X-ray dipper MAXI J1305-704 is a dynamically confirmed black hole (BH) X-ray binary discovered a decade ago. While its only outburst has been studied in detail in X-rays, follow-up at other wavelengths has been scarce. We report here the results from an optical spectroscopy campaign across the outburst of MAXI J1305-704. We analysed two epochs of data obtained by the Magellan Clay Telescope during two consecutive nights, when the source was in a soft X-ray spectral state. We identified typical emission lines from outbursting low-mass X-ray binaries, such as the hydrogen Balmer series, He II 4686 angstrom and the Bowen blend. We focused our analysis on the prominent H alpha line, which exhibits asymmetric emission and variable absorption components. We applied both traditional analytical methods and machine-learning techniques in order to explore the association of the absorption features with outflowing phenomena, and we conclude that they are best explained by broad absorption. This result is consistent with reports from other outbursting BHs, where optical outflows have predominantly been observed in the hard state. Further observations at different X-ray states are key to properly test whether this behaviour is universal and to determine the implications for the disc wind physics