1,653 research outputs found

    Introducing “CORA,” the Community of Online Research Assignments Repository

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    This session will introduce CORA (Community of Online Research Assignments), a pilot open access educational resource developed for faculty and librarians in higher education. Librarians at Loyola Marymount University (LMU) received a Statewide California Electronic Library Consortium (SCELC) Project Initiatives Fund grant to create an online open access repository of user contributed research and information literacy assignments targeted to SCELC institutions. This session will cover the timeline of events during the first year of development, ending with a demo of the live online prototype. LMU faculty provided input on the characteristics of effective research assignments and the desired features in a searchable open access repository. The Cherry Hill Company was contracted to build and host a live prototype of the CORA website using Drupal, an open source content management platform . The current collection of research assignments will be extended and enriched by user contributed assignments, building a community of faculty and librarians sharing their knowledge of pedagogy, information literacy, research and writing within the landscape of higher education. All teaching resources contributed to this collection are released under an intellectual property license that permits their free use and re-purposing by other educators, allowing the assignments to be enhanced by user feedback in order to build a rich corpus of best practices. A live demo of CORA will highlight policies and procedures for acceptable use along with search capabilities, sample assignments, and teaching resources. CORA promotes and encourages the sharing of success and lessons learned so its entire community can benefit

    The Third sector in France and the Labour Market Policy

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    In France, like in other Western European countries, the third sector has been on a steady increase during the last decade as the results of the Johns Hopkins comparative project shows it. Today nonprofit organisations play also an increasing role in labour market policies. In a country with a corporatist welfare state, the access to the labour-market represents the key for social rights

    Three-loop QCD corrections and b-quark decays

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    We present three-loop (NNNLO) corrections to the heavy-to-heavy quark transitions in the limit of equal initial and final quark masses. In analogy with the previously found NNLO corrections, the bulk of the result is due to the beta_0^2 alpha_s^3 corrections. The remaining genuine three-loop effects for the semileptonic b --> c decays are estimated to increase the decay amplitude by 0.2(2)%. The perturbative series for the heavy-heavy axial current converges very well.Comment: 5 page

    Universal Fluctuations in Correlated Systems

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    The probability density function (PDF) of a global measure in a large class of highly correlated systems has been suggested to be of the same functional form. Here, we identify the analytical form of the PDF of one such measure, the order parameter in the low temperature phase of the 2D-XY model. We demonstrate that this function describes the fluctuations of global quantities in other correlated, equilibrium and non-equilibrium systems. These include a coupled rotor model, Ising and percolation models, models of forest fires, sand-piles, avalanches and granular media in a self organized critical state. We discuss the relationship with both Gaussian and extremal statistics.Comment: 4 pages, 2 figure

    Identification of Domains of the HPV11 E1 Protein Required for DNA Replication in Vitro

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    AbstractThe HPV E1 and E2 proteins along with cellular factors, are required for replication of the viral genome. In this study we show that in vitro synthesized HPV11 E1 can support DNA replication in a cell-free system and is able to cooperate with E2 to recruit the host polymerase α primase to the HPV origin in vitro. Deletion analysis revealed that the N-terminal 166 amino acids of E1, which encompass a nuclear localization signal and a cyclin E-binding motif, are dispensable for E1-dependent DNA replication and for recruitment of pol α primase to the origin in vitro. A shorter E1 protein lacking the N-terminal 190 amino acids supported cell-free DNA replication at less than 25% the efficiency of wild-type E1 and was active in the pol α primase recruitment assay. An even shorter E1 protein lacking a functional DNA-binding domain due to a truncation of the N-terminal 352 amino acids was inactive in both assays despite the fact that it retains the ability to associate with E2 or pol α primase in the absence of ori DNA. We provide additional functional evidence that E1 interacts with pol α primase through the p70 subunit of the complex by showing that p70 can be recruited to the HPV origin by E1 and E2 in vitro, that the domain of E1 (amino acids 353–649) that binds to pol α primase in vitro is the same as that needed for interaction with p70 in the yeast two-hybrid system, and that exogenously added p70 competes with the interaction between E1 and pol α primase and inhibits E1-dependent cell-free DNA replication. On the basis of these results and the observation that pol α primase competes with the interaction between E1 and E2 in solution, we propose that these three proteins assemble at the origin in a stepwise process during which E1, following its interaction with E2, must bind to DNA prior to interacting with pol α primase

    Finite size scaling in the 2D XY-model and generalized universality

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    In recent works (BHP), a generalized universality has been proposed, linking phenomena as dissimilar as 2D magnetism and turbulence. To test these ideas, we performed a MC study of the 2D XY-model. We found that the shape of the probability distribution function for the magnetization M is non Gaussian and independent of the system size --in the range of the lattice sizes studied-- below the Kosterlitz-Thoules temperature. However, the shape of these distributions does depend on the temperature, contrarily to the BHP's claim. This behavior is successfully explained by using an extended finite-size scaling analysis and the existence of bounds for M.Comment: 7 pages, 5 figures. Submitted to Phys. Rev. Lett. Details of changes: 1. We emphasized in the abstract the range of validity of our results. 2. In the last paragraph the temperature dependence of the PDF was slightly re-formulate

    Constraints on Low-Mass WIMP Interactions on 19F from PICASSO

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    Recent results from the PICASSO dark matter search experiment at SNOLAB are reported. These results were obtained using a subset of 10 detectors with a total target mass of 0.72 kg of 19F and an exposure of 114 kgd. The low backgrounds in PICASSO allow recoil energy thresholds as low as 1.7 keV to be obtained which results in an increased sensitivity to interactions from Weakly Interacting Massive Particles (WIMPs) with masses below 10 GeV/c^2. No dark matter signal was found. Best exclusion limits in the spin dependent sector were obtained for WIMP masses of 20 GeV/c^2 with a cross section on protons of sigma_p^SD = 0.032 pb (90% C.L.). In the spin independent sector close to the low mass region of 7 GeV/c2 favoured by CoGeNT and DAMA/LIBRA, cross sections larger than sigma_p^SI = 1.41x10^-4 pb (90% C.L.) are excluded.Comment: 23 pages, 7 figures, to be published in Phys. Lett.

    Background Rejection in the DMTPC Dark Matter Search Using Charge Signals

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    The Dark Matter Time Projection Chamber (DMTPC) collaboration is developing low-pressure gas TPC detectors for measuring WIMP-nucleon interactions. Optical readout with CCD cameras allows for the detection for the daily modulation in the direction of the dark matter wind, while several charge readout channels allow for the measurement of additional recoil properties. In this article, we show that the addition of the charge readout analysis to the CCD allows us too obtain a statistics-limited 90% C.L. upper limit on the e−e^- rejection factor of 5.6×10−65.6\times10^{-6} for recoils with energies between 40 and 200 keVee_{\mathrm{ee}}. In addition, requiring coincidence between charge signals and light in the CCD reduces CCD-specific backgrounds by more than two orders of magnitude.Comment: 8 pages, 6 figures. For proceedings of DPF 2011 conferenc

    1/f Noise and Extreme Value Statistics

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    We study the finite-size scaling of the roughness of signals in systems displaying Gaussian 1/f power spectra. It is found that one of the extreme value distributions (Gumbel distribution) emerges as the scaling function when the boundary conditions are periodic. We provide a realistic example of periodic 1/f noise, and demonstrate by simulations that the Gumbel distribution is a good approximation for the case of nonperiodic boundary conditions as well. Experiments on voltage fluctuations in GaAs films are analyzed and excellent agreement is found with the theory.Comment: 4 pages, 4 postscript figures, RevTe
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