Análise da variabilidade do IRI obtido por vários perfilómetros

A irregularidade longitudinal, caracterizada habitualmente pelo Índice Internacional de Irregularidade (IRI – International Roughness Index), é um dos parâmetros de estado dos pavimentos rodoviários cuja variabilidade pode ter consequências relevantes nas estratégias de reabilitação e, consequentemente, nos custos e na sua vida de serviço. Por esta razão, este artigo tem por principal objectivo proporcionar às entidades referidas informação útil no que respeita à variabilidade do IRI, calculado a partir de dados obtidos por vários perfilómetros. Assim, foram seleccionados cinco veículos do tipo”multifunções”, que pertencem quer a empresas de consultadoria quer a instituições de investigação, e três trechos de estrada com camadas de desgaste em betão betuminoso drenante, betão betuminosos rugoso e betão betuminoso “convencional”. Cada veículo percorreu cinco vezes cada trecho nos dois sentidos de tráfego. O espaçamento adoptado para o cálculo do IRI foi de 100 m. A média e o desvio padrão foram os parâmetros usados para estudar a variabilidade dos resultados. De uma forma geral verificou-se que o valor do desvio padrão do IRI é 20 a 30% do valor da média

Stability of Fried Olive and Sunflower Oils Enriched with Thymbra capitata Essential Oil

The stability of olive and sunflower oils for domestic uses after frying cow steak or only heating were evaluated in the presence or absence of the carvacrol-rich essential oil of Thymbra capitata. The treatments consisted of sunflower and olive oils either enriched with 200 mg/l of T. capitata oil or without it, heating at 180°C for 20 min, or frying 100 g cow steak at the same temperature and for the same period of time. In all assays, acid, peroxide, and p-anisidine values were followed over time. The fatty acid profile was estimated before heating or frying as well as at the end of the experiment. The results showed that the type of fat as well as the type of treatment (frying or heating) was determinant for the acid, peroxide, and p-anisidine values found. The presence of the essential oil also demonstrated to affect those values depending on the type of the oil as well as on the type of the treatment (frying or heating). In contrast, the fatty acid profile did not change greatly

Antioxidant activity of thymbra capitata essential oil in meat-treated oil

Several synthetic antioxidants such as butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), and tertiary butyl hydroquinone (TBHQ), have been used to preserve meat. Nevertheless they are considered toxic and to have carcinogenic effects. Natural products, such as those present in essential oils, have been the target of studies as alternative antioxidants, showing promising results. In addition, these natural compounds have the advantage of having consumer's acceptance. Thymbra capitata is a perennial, herbaceous shrub commonly used as a spicy herb. The essential oils isolated from this plant showed antimicrobial and antioxidant activities. The main goal of the present work was to evaluate the capacity of T. capitata oil to prevent lipid oxidation in bovine meat. Different concentrations of essential oil (0, 50, 75 and 100 mg/5 g of meat) were used in two types of bovine meat samples purchased in the local market. The protein content of both types of meat samples was 21%, and lipid content ranged from 9% to 15%. After covering with the oil, the two types of meat samples were stored at -17 degrees C, for one month. After 1 day, 15 days and 30 days, meat samples were taken and cooked at 85 degrees C for 90 min. The samples were then submitted to the TBARS modified method, for antioxidant activity evaluation. The essential oil was able to prevent meat oxidation even after one month of storage and showed a dose-dependent activity

Microarray in clinical practice – utility vs complexity. Mixed phenotype of duplication 15q11.2q13.1 and deletion 16p11.2

Introduction: There’s a consensus to perform chromosomal microarray technique as first-tier clinical diagnostic test for individuals with developmental disabilities. However, given the complexity of clinical presentations, often several diagnostic methods are held before conducting microarray. Method: We report the case of a 5 year-old boy referred to Medical Genetics due to short stature, developmental disabilities and facial dysmorphic features. He was born from eutocic delivery after an uneventful pregnancy. He had psychomotor milestones delayed like sitting at 9 months and walking at 24 months, holding an immature broad-based gait. There was history of learning difficulties from both parents, and the mother has also short stature. On examination it was noted some facial dysmorphic features like high forehead, conical canines and rarefaction of the distal portion of the eyebrows. Due to the history of an episode of transient ataxia, and suspicion of an inherited metabolic disorder, he had already performed various analytical and imaging screenings, all normal. Results: Chromosomal microarray analysis revealed two pathogenic Copy Number Variants (CNV’s): 16p11.2 deletion and 15q11.2q13.1 duplication. The 15q11q13 microduplication syndrome (OMIM # 608636) is a very rare clinical entity with about 30 reported cases with maternal origin, and it is characterized by neurobehavioral disorder, hypotonia, cognitive impairment, epilepsy and short stature. The 16p11.2 microdeletion syndrome (OMIM # 613444) is also a rare clinical entity, with high penetrance, associated with obesity and developmental disabilities. Discussion: Despite the unquestionable utility of microarray, the correlation of the CNV's with the phenotype is often difficult by the rarity of these new microdeletion/duplication clinical entities. In this case the interpretation has increased difficulty because of the simultaneous existence of two distinct clinical entities. Segregation studies, which in the first step include parental analysis, are essential for genetic counseling and determining the risk of recurrence but also for a more accurate correlation genotype-phenotype

Potential toxic elements in stream sediments, soils and waters in an abandoned radium mine (central Portugal)

The Alto da Várzea radium mine (AV) exploited ore and U-bearing minerals, such as autunite and torbernite. The mine was exploited underground from 1911 to 1922, closed in 1946 without restoration, and actually a commercial area is deployed. Stream sediments, soils and water samples were collected between 2008 and 2009. Stream sediments are mainly contaminated in As, Th, U and W, which is related to the AV radium mine. The PTEs, As, Co, Cr, Sr, Th, U, W, Zn, and electrical conductivity reached the highest values in soils collected inside the mine influence. Soils are contaminated with As and U and must not be used for any purpose. Most waters have pH values ranging from 4.3 to 6.8 and are poorly mineralized (EC = 41-186 µS/cm; TDS = 33-172 mg/L). Groundwater contains the highest Cu, Cr and Pb contents. Arsenic occurs predominantly as H2(AsO4)- and H(AsO4)2-. Waters are saturated in goethite, haematite and some of them also in lepidocrocite and ferrihydrite, which adsorbs As (V). Lead is divalent in waters collected during the warm season, being mobile in these waters. Thorium occurs mainly as Th(OH)3(CO3)-, Th(OH)2(CO3) and Th(OH)2(CO3) 22- , which increase water Th contents. Uranium occurs predominantly as UO2CO3, but CaUO2(CO3) 32- and CaUO2(CO3)3 also occur, decreasing its mobility in water. The waters are contaminated in NO2-, Mn, Cu, As, Pb and U and must not be used for human consumption and in agricultural activities. The water contamination is mainly associated with the old radium mine and human activities. A restoration of the mining area with PTE monitoring is necessary to avoid a public hazard.Thanks are due to Prof. Joao Coutinho for the determination of organic matter and cation exchange capacity in samples of stream sediments and soils and A. Rodrigues for the water analyses, EDM for some information on the Alto da Varzea mine area. This study had the support of Portuguese Fundacao para a Ciencia e Tecnologia (FCT), through the strategic projects UID/GEO/04035/2013 and UID/MAR/04292/2013 (MARE).info:eu-repo/semantics/publishedVersio