Individual specialization, learning and information transfer in social hymenopterans: experiments, ideas and hypotheses

Peer reviewe

Pengaruh Model Pembelajaran Kooperatif Tipe Group Investigation terhadap Hasil Belajar Siswa pada Pembelajaran Tematik di Sekolah Dasar

Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan model pembelajaran kooperatif tipe group investigation terhadap hasil belajar siswa pada tema daerah tempat tinggalku di SD Swasta Advent Timbang Deli Medan kelas IV pada tahun 2020/2021. Jenis Penelitian ini adalah kuantitatif dengan menggunakan metode deskriptip analitik. Populasi dalam penelitian ini seluruh siswa kelas IV yang diteliti satu kelas berjumlah 35 siswa. Pengambilan sampel dengan menggunakan sampling jenuh. Berdasarkan hasil penelitian ini menunjukan bahwa hasil belajar siswa dengan menggunakan model pembelajaran kooperatif tipe group investigation termasuksud kategori sangat baik dengan rata-rata 87,23. Hasil penelitian ini menunjukan bahwa hasil pengujian korelasi dapat dilihat pada nilai koefisien korelasi sebesar 0,640 artinya rhitung (0,640) > rtabel (0,361) maka ha diterima maka terdapat pengaruh yang kuat antara model pembelajaran kooperatif tipe group investigation terhadap hasil belajar siswa pada tema daerah tempat tinggalku di kelas IV SD Swasta Advent Timbang Deli Medan dapat juga dilihat dari hasil pengujian uji-t dimana thitung > ttabel yaitu 4,786 > 1,703 sehingga menyatakan bawah hipotesis Ha diterim

Design of terrace drainage networks using UAV-based high-resolution topographic data

Hillslope viticulture has a long history in Mediterranean Europe, and still holds important cultural and economic value. Steep hillsides have widely been levelled by terraces, in order to control surface water flow and facilitate cultivation. However, under unsustainable management and growing rainfall aggressiveness, terraced vineyards have become one of the most erosion-prone agricultural landscapes. The Valcamonica valley in Lombardy (Italy) presents a typical example of an ancient wine production region where rural land abandonment has previously caused widespread degradation of the traditional terracing systems. Recently, a local revival of wine production led to restoration plans of the terraces and their drainage functioning, to safeguard productivity and hydrogeologic safety. In this study, an Unmanned Aerial Vehicle (UAV) survey was carried out to reconstruct an accurate and precise 3D terrain model of a Valcamonica vineyard. through photogrammetry. The resulting high-resolution topographic data allowed insights of surface flow-induced soil erosion patterns based on the Relative Path Impact Index (RPII). Three diverse drainage networks were designed and digitally implemented, allowing scenario analysis of the costs and benefits in terms of potential erosion mitigation. The presented methodology could likely improve the time-efficiency and cost-effectiveness of similar restoration plans in degraded landscapes

3D-printed microfluidics integrated with optical nanostructured porous aptasensors for protein detection

Microfluidic integration of biosensors enables improved biosensing performance and sophisticated lab-on-a-chip platform design for numerous applications. While soft lithography and polydimethylsiloxane (PDMS)-based microfluidics are still considered the gold standard, 3D-printing has emerged as a promising fabrication alternative for microfluidic systems. Herein, a 3D-printed polyacrylate-based microfluidic platform is integrated for the first time with a label-free porous silicon (PSi)–based optical aptasensor via a facile bonding method. The latter utilizes a UV-curable adhesive as an intermediate layer, while preserving the delicate nanostructure of the porous regions within the microchannels. As a proof-of-concept, a generic model aptasensor for label-free detection of his-tagged proteins is constructed, characterized, and compared to non-microfluidic and PDMS-based microfluidic setups. Detection of the target protein is carried out by real-time monitoring reflectivity changes of the PSi, induced by the target binding to the immobilized aptamers within the porous nanostructure. The microfluidic integrated aptasensor has been successfully used for detection of a model target protein, in the range 0.25 to 18 μM, with a good selectivity and an improved limit of detection, when compared to a non-microfluidic biosensing platform (0.04 μM vs. 2.7 μM, respectively). Furthermore, a superior performance of the 3D-printed microfluidic aptasensor is obtained, compared to a conventional PDMS-based microfluidic platform with similar dimensions. Graphical abstract: [Figure not available: see fulltext.]. © 2021, The Author(s)

3D-printed microfluidics integrated with optical nanostructured porous aptasensors for protein detection

Microfluidic integration of biosensors enables improved biosensing performance and sophisticated lab-on-a-chip platform design for numerous applications. While soft lithography and polydimethylsiloxane (PDMS)-based microfluidics are still considered the gold standard, 3D-printing has emerged as a promising fabrication alternative for microfluidic systems. Herein, a 3D-printed polyacrylate-based microfluidic platform is integrated for the first time with a label-free porous silicon (PSi)–based optical aptasensor via a facile bonding method. The latter utilizes a UV-curable adhesive as an intermediate layer, while preserving the delicate nanostructure of the porous regions within the microchannels. As a proof-of-concept, a generic model aptasensor for label-free detection of his-tagged proteins is constructed, characterized, and compared to non-microfluidic and PDMS-based microfluidic setups. Detection of the target protein is carried out by real-time monitoring reflectivity changes of the PSi, induced by the target binding to the immobilized aptamers within the porous nanostructure. The microfluidic integrated aptasensor has been successfully used for detection of a model target protein, in the range 0.25 to 18 μM, with a good selectivity and an improved limit of detection, when compared to a non-microfluidic biosensing platform (0.04 μM vs. 2.7 μM, respectively). Furthermore, a superior performance of the 3D-printed microfluidic aptasensor is obtained, compared to a conventional PDMS-based microfluidic platform with similar dimensions. Graphical abstract: [Figure not available: see fulltext.]. © 2021, The Author(s)

Pengaruh Pengelolaan Kelas Terhadap Keaktifan Belajar Peserta Didik Kelas IV SD Negeri 068006 Simalingkar

Penelitian ini bermaksud untuk mengetahui pengaruh pengelolaan kelas terhadap keaktifan belajar peserta didik kelas IV SD N 068006 Simalingkar Tahun Pembelajaran 2022/2023. Metode yang dipakai dalam penelitian ini ialah metode expost facto, populasi dari penelitian ini keseluruhan peserta didik dengan jumlah 181 yang terbagi dalam 6 ruangan.  Sampel dalam penelitian ini memakai purposive sampel dan yang dipilih ialah peserta didik kelas IV dengan jumlah 30 peserta didik. Hasil penelitian ini menunjukkan pengelolaan kelas di kelas IV SD Negeri 068006 Simalingkar tergolong dalam tingkat sedang pada persentase 70% dankeaktifan belajar peserta didik juga berada pada tingkat sedang pada persentase 67 %. Dari hasil uji korelasi sebesar 0.612 yang artinya rhitung (0.612) ≥ rtabel (0.361) maka Ha diterima. Maka terdapat pengaruh yang kuat antara pengelolaan kelas terhadap kekatifan belajar peserta didik. Dari hasil penelitian uji-T dimana thitung ≥ ttabel yaitu 4,098 ≥ 2,048 maka dapat dinyatakan bahwa Ha diterima. Hal ini menunjukkan bahwa adanya pengaruh positif dan signiifikan dari pengelolaan kelas terhadap kekatifan belajar peserta didik kelas IV SD N 068006 Simalingkar tahun pembelajaran 2022/2023

Lung ultrasound predicts clinical course but not outcome in COVID-19 ICU patients: a retrospective single-center analysis

BACKGROUND Point-of-care lung ultrasound (LU) is an established tool in the first assessment of patients with coronavirus disease (COVID-19). Purpose of this study was to evaluate the value of lung ultrasound in COVID-19 intensive care unit (ICU) patients in predicting clinical course and outcome. METHODS We analyzed lung ultrasound score (LUS) of all COVID-19 patients admitted from March 2020 to December 2020 to the Internal Intensive Care Unit, Ludwig-Maximilians-University (LMU) of Munich. LU was performed according to a standardized protocol at ICU admission and in case of clinical deterioration with the need for intubation. A normal lung scores 0 points, the worst LUS has 24 points. Patients were stratified in a low (0-12 points) and a high (13-24 points) lung ultrasound score group. RESULTS The study included 42 patients, 69% of them male. The most common comorbidities were hypertension (81%) and obesity (57%). The values of pH (7.42 ± 0.09 vs 7.35 ± 0.1; p = 0.047) and paO2 (107 80-130 vs 80 66-93 mmHg; p = 0.034) were significantly reduced in patients of the high LUS group. Furthermore, the duration of ventilation (12.5 8.3-25 vs 36.5 9.8-70 days; p = 0.029) was significantly prolonged in this group. Patchy subpleural thickening (n = 38; 90.5{\%}) and subpleural consolidations (n = 23; 54.8{\%}) were present in most patients. Pleural effusion was rare (n = 4; 9.5{\%}). The median total LUS was 11.9 ± 3.9 points. In case of clinical deterioration with the need for intubation, LUS worsened significantly compared to baseline LU. Twelve patients died during the ICU stay (29{\%}). There was no difference in survival in both LUS groups (75{\%} vs 66.7{\%}, p = 0.559). CONCLUSIONS LU can be a useful monitoring tool to predict clinical course but not outcome of COVID-19 ICU patients and can early recognize possible deteriorations

The effect of connective tissue graft or a collagen matrix on epithelial differentiation around teeth and implants: a preclinical study in minipigs.

OBJECTIVES This study aimed to histologically evaluate the healing at 8 weeks after coronally advanced flap (CAF) with either a superficial (SCTG) or deep palatal connective tissue graft (DCTG), or a collagen matrix (CM) to cover recession defects at teeth and implants. MATERIAL AND METHODS One mandibular side of 6 miniature pigs received each 3 titanium implants 12 weeks after extraction. Eight weeks later, recession defects were created around implants and contralateral premolars and 4 weeks later randomly subjected to CAF + SCTG, CAF + DCTG, or CAF + CM. After 8 weeks, block biopsies were histologically analyzed. RESULTS For the primary outcome, i.e., keratinization of the epithelium, all teeth and implants exhibited a keratinized epithelium with no histological differences among them also not in terms of statistically significant differences in length (SCTG 0.86 ± 0.92 mm, DCTG 1.13 ± 0.62 mm, and Cm, 1.44 ± 0.76 mm). Pocket formation was histologically seen at all teeth, around most implants with SCTG and DCTG, however not in the CM implant group. The connective tissue grafts showed hardly signs of degradation, whereas the CM was partly degraded and integrated in connective tissue. The mean gain in gingival height was similar in all experimental groups (SCTG 3.89 ± 0.80 mm, DCTG 4.01 ± 1.40 mm, CM 4.21 ± 0.64 mm). Statistically significant differences were found in the height of the junctional epithelium between the control teeth and the connective tissue groups (p = 0.009 and 0.044). CONCLUSIONS In this animal model, the use of either a superficial or deep connective tissue graft or a collagen membrane did not seem to have any impact on the epithelial keratinization around both teeth and implants. All procedures (CAF + SCTG/DCTG/CM) resulted in a long JE that was even longer at implants. CLINICAL RELEVANCE Deep/superficial palatal connective tissue graft yielded similar keratinization around teeth/implants. Given the absence of pocket formation and inflammatory processes at implants when using a CM, CAF + CM might bear potential clinical benefits