Resonant generation and refraction of dispersive shock waves in one-dimensional nonlinear Schrödinger flows

In the Thesis, two important theoretical problems arising in the theory of one-dimensional defocusing nonlinear Schrödinger (NLS) flows are investigated analytically and numerically: (i) the resonant generation of dispersive shock waves (DSWs) in one-dimensional NLS flow past a broad repulsive penetrable barrier; and (ii) the interaction of counter-propagating DSW and a simple rarefaction wave (RW), which is referred to as the DSW refraction problem. The first problem is motivated by the recent experimental observations of dark soliton radiation in a cigar-shaped BEC by sweeping through it a localised repulsive potential; the second problem represents a dispersive-hydrodynamic counterpart of the classical gas-dynamics problem of the shock wave refraction on a RW, and, apart from its theoretical significance could also find applications in superfluid dynamics. Both problems also naturally arise in nonlinear optics, where the NLS equation is a standard mathematical model and the `superfluid dynamics of light' can be used for an all-optical modelling of BEC flows. The main results of the Thesis are as follows: (i) In the problem of the transcritical flow of a BEC through a wide repulsive penetrable barrier an asymptotic analytical description of the arising wave pattern is developed using the combination of the localised ``hydraulic'' solution of the 1D Gross-Pitaevskii (GP) equation with repulsion (the defocusing NLS equation with an added external potential) and the appropriate exact solutions of the Whitham-NLS modulation equations describing the resolution of the upstream and downstream discontinuities through DSWs. We show that the downstream DSW effectively represents the train of dark solitons, which can be associated with the excitations observed experimentally by Engels and Atherton (2008). (ii) The refraction of a DSW due to its head-on collision with the centred RW is considered in the frameworks of two one-dimensional defocusing NLS models: the standard cubic NLS equation and the NLS equation with saturable nonlinearity, the latter being a standard model for the light propagation through photorefractive optical crystals. For the cubic nonlinearity case we present a full asymptotic description of the DSW refraction by constructing appropriate exact solutions of the Whitham modulation equations in Riemann invariants. For the NLS equation with saturable nonlinearity, whose modulation system does not possess Riemann invariants, we take advantage of the recently developed method for the DSW description in non-integrable dispersive systems to obtain key parameters of the DSW refraction. In both problems, we undertake a detailed analysis of the flow structure for different parametric regimes and calculate physical quantities characterising the output flows in terms of relevant input parameters. Our modulation theory analytical results are supported by direct numerical simulations of the corresponding full dispersive initial value problems (IVP)

Adopsi Inovasi Media Sosial Mahasiswa Jurusan Ilmu Komunikasi FDK UIN Suska Riau (Studi Kasus Konsentrasi Public Relations)

Penelitian ini bertujuan untuk mengetahui adopsi inovasi media sosial mahasiswa Konsentrasi Public Relations Jurusan Ilmu Komunikasi Fakultas Dakwah dan Komunikasi UIN Sultan Syarif Kasim Riau. Dengan pendekatan kuantitatif menggunakan metode survei deskriptif secara online terhadap 100 mahasiswa semester 5 yang terdaftar pada kelas e-learning UIN Suska, diperoleh temuan bahwa adopsi inovasi media sosial sebagian besar didominasi oleh penggunaan jejaring sosial khususnya Facebook, Twitter dan Instagram. Sedangkan Blog, Youtube dan Kaskus masih sedikit diadopsi oleh mahasiswa. Dalam komunikasi inovasi media sosial, peran dosen sebagai sumber pengetahuan dan persuasi masih rendah. Komunikator inovasi sebagian besar berasal dari jejaring pertemanan. Adopter media sosial sebagian besar tetap terus melanjutkan adopsi karena dinilai bermanfaat bagi eksistensi diri dan pendukung studi

Refraction of dispersive shock waves

We study a dispersive counterpart of the classical gas dynamics problem of the interaction of a shock wave with a counter-propagating simple rarefaction wave, often referred to as the shock wave refraction. The refraction of a one-dimensional dispersive shock wave (DSW) due to its head-on collision with the centred rarefaction wave (RW) is considered in the framework of the defocusing nonlinear Schrödinger (NLS) equation. For the integrable cubic nonlinearity case we present a full asymptotic description of the DSW refraction by constructing appropriate exact solutions of the Whitham modulation equations in Riemann invariants. For the NLS equation with saturable nonlinearity, whose modulation system does not possess Riemann invariants, we take advantage of the recently developed method for the DSW description in non-integrable dispersive systems to obtain main physical parameters of the DSW refraction. The key features of the DSW-RW interaction predicted by our modulation theory analysis are confirmed by direct numerical solutions of the full dispersive problem

The iPlant Collaborative: Cyberinfrastructure for Enabling Data to Discovery for the Life Sciences

The iPlant Collaborative provides life science research communities access to comprehensive, scalable, and cohesive computational infrastructure for data management; identity management; collaboration tools; and cloud, high-performance, high-throughput computing. iPlant provides training, learning material, and best practice resources to help all researchers make the best use of their data, expand their computational skill set, and effectively manage their data and computation when working as distributed teams. iPlant's platform permits researchers to easily deposit and share their data and deploy new computational tools and analysis workflows, allowing the broader community to easily use and reuse those data and computational analyses

Modelling full waveform Lidar data on forest structures at plot level : a sensitivity analysis of forest and sensor main characteristics on full-waveform simulated data

[Departement_IRSTEA]Territoires [TR1_IRSTEA]SYNERGIE [Axe_IRSTEA]TETIS-ATTOSSilviLaser, La Grande Motte, FRA, 28-/09/2015 - 30/09/2015International audienceA new approach for LIDAR altimetry mission for biomass applications (tree height measurement) is explored based on low emitted laser energy at high repetition frequency. Low energy approach drastical ly reduces the laser induced risks. Altimetry performances meet preliminary science requirements . The proposed instrument design is compatible with a space mission

FGF signalling through RAS/MAPK and PI3K pathways regulates cell movement and gene expression in the chicken primitive streak without affecting E-cadherin expression

<p>Abstract</p> <p>Background</p> <p>FGF signalling regulates numerous aspects of early embryo development. During gastrulation in amniotes, epiblast cells undergo an epithelial to mesenchymal transition (EMT) in the primitive streak to form the mesoderm and endoderm. In mice lacking FGFR1, epiblast cells in the primitive streak fail to downregulate E-cadherin and undergo EMT, and cell migration is inhibited. This study investigated how FGF signalling regulates cell movement and gene expression in the primitive streak of chicken embryos.</p> <p>Results</p> <p>We find that pharmacological inhibition of FGFR activity blocks migration of cells through the primitive streak of chicken embryos without apparent alterations in the level or intracellular localization of E-cadherin. E-cadherin protein is localized to the periphery of epiblast, primitive streak and some mesodermal cells. FGFR inhibition leads to downregulation of a large number of regulatory genes in the preingression epiblast adjacent to the primitive streak, the primitive streak and the newly formed mesoderm. This includes members of the FGF, NOTCH, EPH, PDGF, and canonical and non-canonical WNT pathways, negative modulators of these pathways, and a large number of transcriptional regulatory genes. <it>SNAI2 </it>expression in the primitive streak and mesoderm is not altered by FGFR inhibition, but is downregulated only in the preingression epiblast region with no significant effect on E-cadherin. Furthermore, over expression of SNAIL has no discernable effect on E-cadherin protein levels or localization in epiblast, primitive streak or mesodermal cells. FGFR activity modulates distinct downstream pathways including RAS/MAPK and PI3K/AKT. Pharmacological inhibition of MEK or AKT indicate that these downstream effectors control discrete and overlapping groups of genes during gastrulation. FGFR activity regulates components of several pathways known to be required for cell migration through the streak or in the mesoderm, including RHOA, the non-canonical WNT pathway, PDGF signalling and the cell adhesion protein N-cadherin.</p> <p>Conclusions</p> <p>In chicken embryos, FGF signalling regulates cell movement through the primitive streak by mechanisms that appear to be independent of changes in E-cadherin expression or protein localization. The positive and negative effects on large groups of genes by pharmacological inhibition of FGF signalling, including major signalling pathways and transcription factor families, indicates that the FGF pathway is a focal point of regulation during gastrulation in chicken.</p

Long-term health outcomes of allogeneic hematopoietic stem cell transplantation

BackgroundFifty years of hematopoietic cell transplantation (HCT) has ushered in an exciting era of cellular therapy and has led to enormous progress in improving the outcomes of patients with both malignant and non-malignant hematologic disease. As the survival of transplanted patients has increased, so has the recognition of long-term complications related to this therapy.PurposeThe goal of this review is to highlight some of the most common long-term complications of HCT.Data sourcesTo this end, we have conducted a review of the published literature on the long-term complications of HCT encompassing the past 50 years.Study selectionWe have endeavored to include long-term complications reported in research articles, case series and case reports, reviews, and abstracts. We have focused primarily on adult allogeneic HCT, but have included some data from studies of pediatric allogeneic HCT as well. We have also prioritized the literature published in the last 15 years.Data extractionKey data supporting the onset and prevalence of the most common long-term complications was extracted.LimitationsWhile the list of long-term complications extracted and reported was comprehensive, it was not exhaustive.ConclusionsWe have endeavored to highlight some of the most common long-term complications of HCT, the recognition and management of which constitutes an important part of HCT survivorship care

Live Attenuated Varicella-Zoster Vaccine in Hematopoietic Stem Cell Transplantation Recipients

AbstractHematopoietic stem cell transplantation (HSCT) recipients are at risk for varicella-zoster virus (VZV) reactivation. Vaccination may help restore VZV immunity; however, the available live attenuated VZV vaccine (Zostavax) is contraindicated in immunocompromised hosts. We report our experience with using a single dose of VZV vaccine in 110 adult autologous and allogeneic HSCT recipients who were about 2 years after transplantation, free of graft-versus-host disease, and not receiving immunosuppression. One hundred eight vaccine recipients (98.2%) had no clinically apparent adverse events with a median follow-up period of 9.5 months (interquartile range, 6 to 16; range, 2 to 28). Two vaccine recipients (1.8%) developed a skin rash (one zoster-like rash with associated pain, one varicella-like) within 42 days post-vaccination that resolved with antiviral therapy. We could not confirm if these rashes were due to vaccine (Oka) or wild-type VZV. No other possible cases of VZV reactivation have occurred with about 1178 months of follow-up. Live attenuated zoster vaccine appears generally safe in this population when vaccinated as noted; the overall vaccination risk needs to be weighed against the risk of wild-type VZV disease in this high-risk population

Maxillofacial brown tumours: Series of 5 cases.

OBJECTIVES: Brown tumours are benign bone tumours secondary to hyperparathyroidism. The authors describe the various clinical features, diagnostic methods and treatment modalities for maxillofacial brown tumours. MATERIAL AND METHODS: This multicentre retrospective study comprised 5 patients (four women and one man, between the ages of 29 and 70 years) with one or several maxillofacial brown tumours observed over a 16-year period from January 2000 to December 2016. RESULTS: Four patients presented secondary hyperparathyroidism in a context of chronic renal failure, one patient presented primary hyperparathyroidism due to parathyroid adenoma. Three patients presented a mandibular brown tumour, and two patients presented a maxillary brown tumour. The diagnosis was based on histological examination and laboratory tests. Brown tumours were treated either surgically or conservatively. A favourable outcome was observed in all cases. CONCLUSION: Brown tumours are rare lesions. This diagnosis must be considered in a context of giant cell tumour associated with hyperparathyroidism. Brown tumours should be treated conservatively