ANÁLISE DAS ESTRATÉGIAS DIGITAIS ELABORADAS PELA REDE MAGAZINE LUIZA DIANTE DO CENÁRIO DE PANDEMIA (COVID-19).

O presente artigo tem como objetivo principal analisar as estratégias digitais elaboradas pela rede Magazine Luiza diante do cenário de pandemia (COVID-19). Para execução deste artigo, se fez necessário a utilização do método qualitativo-descritivo-exploratório, com bases em pesquisas bibliográficas na área de gestão de marketing e uma pesquisa documental nos resultados divulgados pela própria companhia. Após realizar uma análise dos dados levantados, verificou-se a importância das estratégias elaboradas no ambiente digital e a utilização de um portal de serviços eletrônicos. Desse modo, a utilização das tecnologias da informação e da comunicação impõe novas estratégias para expansão e ampliação de serviços e produtos

Cálculo diferencial e integral evoluindo a inteligência computacional Mediante a linguagem Python de programação: Differential and integral calculus evolving computational intelligence through the Python programming language

A proeminente relevância do Cálculo Diferencial e Integral, na Ciência e na Tecnologia, foram delineadas neste artigo. Explanados computacionalmente, Limites, de Derivadas e de Integrais, foram desenvolvidos em PYTHON, criando uma interface que favorece o processo de ensino-aprendizagem, com característica multidisciplinar. Três estudos estão dispostos no artigo, comprovando a aplicabilidade da estratégia em resultados, analíticos e gráficos, com altíssimo grau de precisão e acurácia.    &nbsp

Educomunicação, Transformação Social e Desenvolvimento Sustentável

Esta publicação apresenta os principais trabalhos dos GTs do II Congresso Internacional de Comunicação e Educação nos temas Transformação social, com os artigos que abordam principalmente Educomunicação e/ou Mídia-Educação, no contexto de políticas de diversidade, inclusão e equidade; e, em Desenvolvimento Sustentável os artigos que abordam os avanços da relação comunicação/educação no contexto da educação ambiental e desenvolvimento sustentável

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others

Formação continuada de professores: quando a experiência e os saberes docentes se limitam à vivência

O artigo discute as noções de experiência e saberes docentes, presentes em artigos sobre formação continuada de professores de Educação Física. Para tanto, identifica a referência teórica mais recorrente no tratamento dessas noções e com ela dialoga a partir das categorias de vivência e experiência presentes em W. Benjamin e T. Adorno. A atual valorização dos saberes da experiência e do protagonismo do professor questiona a racionalidade instrumental, mas preserva a hipertrofia dos meios e dos procedimentos, agora vistos como singulares, intuitivos e provenientes do próprio fazer profissional. O que é chamado de experiência e o saber que dela advém permanecem orientados e limitados à direta utilidade para uma práxis imediata

Detection of QTL associated with rust resistance using IBD-based methodologies in exogamic Eucalyptus spp. populations

In Brazil the rust caused by Puccinia psidii Winter stands out as the most important disease of eucalyptus. The use of resistant genotypes is the main control method, which makes the detection of markers linked to rust resistance essential to the selection of resistant genotypes. In this study, an F1 progeny of 131 plants from interspecific crossings of Eucalyptus was used to identify markers linked to resistance genes for this pathogen. An integrated map was constructed for linkage group three based on microsatellite markers. For QTL mapping two methodologies based on alleles identical-by-descent (IBD) were used: single marker analysis of Haseman and Elston and the interval mapping procedure of Fulker and Cardon. Both methods showed significant association for the Embra 125 marker.The QTL that explained 42 % of the phenotypic variation was mapped to 0.02 cM of this marker by the Fulker and Cardon. Marker Embra 125 has potential use in assisted selection, thus increasing the efficiency of the selection of resistant genotypes

Chemical Composition, Antimicrobial Properties of Siparuna guianensis Essential Oil and a Molecular Docking and Dynamics Molecular Study of its Major Chemical Constituent

The essential oil of Siparuna guianensis was obtained by hydrodistillation. The identification of the chemical compounds was performed by gas chromatography coupled with mass spectrometry (GC/MS). Antimicrobial activity was investigated for four microorganisms: Streptococcus mutans (ATCC 3440), Enterococcus faecalis (ATCC 4083), Escherichia coli (ATCC 25922), and Candida albicans (ATCC-10231). The studies of doping and molecular dynamics were performed with the molecule that presented the highest concentration of drug–target proteins, 1IYL (C. albicans), 1C14 (E. coli), 2WE5 (E. faecalis), and 4TQX (S. mutans). The main compounds identified were: Curzerene (7.1%), γ-Elemene (7.04%), Germacrene D (7.61%), trans-β-Elemenone (11.78%), and Atractylone (18.65%). Gram positive bacteria and fungi were the most susceptible to the effects of the essential oil. The results obtained in the simulation showed that the major compound atractylone interacts with the catalytic sites of the target proteins, forming energetically favourable systems and remaining stable during the period of molecular dynamics

Antimicrobial, cytotoxic activity of the syzygium aromaticum essential oil, molecular docking and dynamics molecular studies of its major chemical constituent

Lambda Alpha International (1427204); Montana Tech (1662230);Federal University of Para. Faculty of Food Engineering. Program of Post-Graduation in Food Science and Technology. Belém, PA, Brazil.Federal University of Para. Laboratory of Preparation and Computation of Nanomaterials. Belém, PA, Brazil.Federal University of Pará. Faculty of Dentistry. Cell Culture Laboratory. Belém, PA, Brazil.Federal University of Para. Program of Post-Graduation in Natural Resources Engineering. Belém, PA, Brazil.Federal University of Pará. Faculty of Dentistry. Cell Culture Laboratory. Belém, PA, Brazil.Federal University of Para. Program of Post-Graduation in Chemistry. Belém, PA, Brazil.Federal University of Pará. Faculty of Dentistry. Cell Culture Laboratory. Belém, PA, Brazil.Federal University of Pará. Faculty of Dentistry. Cell Culture Laboratory. Belém, PA, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.University Center of Pará State. Belém, PA, Brazil.Federal University of Pará. Faculty of Dentistry. Cell Culture Laboratory. Belém, PA, Brazil.Federal University of Para. Laboratory of Preparation and Computation of Nanomaterials. Belém, PA, Brazil.Federal University of Para. Faculty of Food Engineering. Program of Post-Graduation in Food Science and Technology. Belém, PA, Brazil.The objective of the present work was to analyze the cytotoxic, antimicrobial activity and the action mechanism of the major component in of the Syzygium aromaticum essential oil obtained by supercritical CO 2 . In this work, gingival fibroblasts were exposed to the essential oil in different concentrations for one hour: 5 μL/ml, 7.5 μL/ml and 10 μL/ml. Culture medium was used as control. Cytotoxicity analysis was performed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT ® ) method. The susceptibility was evaluated on three microorganisms Candida albicans, Escherichia coli and Staphylococcus aureus. The statistical analyses showed significant difference in cell viability for the concentration of 10 μL/mL, as compared to the control group. As a result, the plant extract had no cytotoxicity at concentrations below 10 μL/mL in human gingival fibroblasts. The interaction mode of eugenol, the major compound and main component responsible for the biological activity of the essential oil was evaluated. The molecular docking of eugenol with important proteins of the metabolic pathway of the microorganisms C. albicans, E. coli and S. aureus were performed. The results demonstrated that the compound is capable of interacting with catalytic residues of the enzymes and forming an energetically favorable system with such proteins. The results of binding free energy obtained demonstrate this capacity. For the eugenol-N-myristoyltransferase (C. albicans) system, the value of ∆G bind was −19.01 kcal/mol, for Enoyl reductase (E. Coli) ∆G bind was equal to −11.31 kcal/mol and for SarA (S. aureus) ∆G bind was −13.58 kcal/mol