13 research outputs found
The Socioeconomic Impacts of the Upper Atmosphere Effects on LEO Satellites, Communication and Navigation Systems
Predicting the Effect of Surface Texture on the Qualitative Form of Prehension
Reach-to-grasp movements change quantitatively in a lawful (i.e. predictable) manner with changes in object properties. We explored whether altering object texture would produce qualitative changes in the form of the precontact movement patterns. Twelve participants reached to lift objects from a tabletop. Nine objects were produced, each with one of three grip surface textures (high-friction, medium-friction and low-friction) and one of three widths (50 mm, 70 mm and 90 mm). Each object was placed at three distances (100 mm, 300 mm and 500 mm), representing a total of 27 trial conditions. We observed two distinct movement patterns across all trials—participants either: (i) brought their arm to a stop, secured the object and lifted it from the tabletop; or (ii) grasped the object ‘on-the-fly’, so it was secured in the hand while the arm was moving. A majority of grasps were on-the-fly when the texture was high-friction and none when the object was low-friction, with medium-friction producing an intermediate proportion. Previous research has shown that the probability of on-the-fly behaviour is a function of grasp surface accuracy constraints. A finger friction rig was used to calculate the coefficients of friction for the objects and these calculations showed that the area available for a stable grasp (the ‘functional grasp surface size’) increased with surface friction coefficient. Thus, knowledge of functional grasp surface size is required to predict the probability of observing a given qualitative form of grasping in human prehensile behaviour
A many-analysts approach to the relation between religiosity and well-being
The relation between religiosity and well-being is one of the most researched topics in the psychology of religion, yet the directionality and robustness of the effect remains debated. Here, we adopted a many-analysts approach to assess the robustness of this relation based on a new cross-cultural dataset (N=10,535 participants from 24 countries). We recruited 120 analysis teams to investigate (1) whether religious people self-report higher well-being, and (2) whether the relation between religiosity and self-reported well-being depends on perceived cultural norms of religion (i.e., whether it is considered normal and desirable to be religious in a given country). In a two-stage procedure, the teams first created an analysis plan and then executed their planned analysis on the data. For the first research question, all but 3 teams reported positive effect sizes with credible/confidence intervals excluding zero (median reported β=0.120). For the second research question, this was the case for 65% of the teams (median reported β=0.039). While most teams applied (multilevel) linear regression models, there was considerable variability in the choice of items used to construct the independent variables, the dependent variable, and the included covariates
A Many-analysts Approach to the Relation Between Religiosity and Well-being
The relation between religiosity and well-being is one of the most researched topics in the psychology of religion, yet the directionality and robustness of the effect remains debated. Here, we adopted a many-analysts approach to assess the robustness of this relation based on a new cross-cultural dataset (N = 10, 535 participants from 24 countries). We recruited 120 analysis teams to investigate (1) whether religious people self-report higher well-being, and (2) whether the relation between religiosity and self-reported well-being depends on perceived cultural norms of religion (i.e., whether it is considered normal and desirable to be religious in a given country). In a two-stage procedure, the teams first created an analysis plan and then executed their planned analysis on the data. For the first research question, all but 3 teams reported positive effect sizes with credible/confidence intervals excluding zero (median reported β = 0.120). For the second research question, this was the case for 65% of the teams (median reported β = 0.039). While most teams applied (multilevel) linear regression models, there was considerable variability in the choice of items used to construct the independent variables, the dependent variable, and the included covariates
Structural Analysis of the Caenorhabditis elegans Dauer Larval Anterior Sensilla by Focused Ion Beam-Scanning Electron Microscopy
At the end of the first larval stage, the nematode Caenorhabditis elegans developing in harsh environmental conditions is able to choose an alternative developmental path called the dauer diapause. Dauer larvae exhibit different physiology and behaviors from non-dauer larvae. Using focused ion beam-scanning electron microscopy (FIB-SEM), we volumetrically reconstructed the anterior sensory apparatus of C. elegans dauer larvae with unprecedented precision. We provide a detailed description of some neurons, focusing on structural details that were unknown or unresolved by previously published studies. They include the following: (1) dauer-specific branches of the IL2 sensory neurons project into the periphery of anterior sensilla and motor or putative sensory neurons at the sub-lateral cords; (2) ciliated endings of URX sensory neurons are supported by both ILso and AMso socket cells near the amphid openings; (3) variability in amphid sensory dendrites among dauers; and (4) somatic RIP interneurons maintain their projection into the pharyngeal nervous system. Our results support the notion that dauer larvae structurally expand their sensory system to facilitate searching for more favorable environments
Proportion of ‘on-the-fly’ movements as a function of surface texture.
<p>The mean coefficient of static friction was 1.31, 0.76 and 0.44 for the high, medium and low friction object surface textures respectively (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032770#s2" target="_blank">Methods</a>).</p
Object geometric properties friction-dependant functional grip area.
<p><i>Upper</i> Geometric variation in stimulus sizes: Grip surface width ‘A’, the distance between the spherical surface centre-points ‘B’ and support base width ‘C’ were varied as discussed in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032770#s2" target="_blank">Method</a> section. <i>Lower a)</i> Manually securing an object requires the frictional force to be greater than the tangential component of object weight at the interface between fingertip and object. A curved surface results in a normal reaction force direction (R<sub>N</sub>) unique to the point at which the object is grasped. Fearing <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032770#pone.0032770-Fearing1" target="_blank">[14]</a> demonstrated that, for a stable grasp, the grip conditions should satisfy: tan<sup>−1</sup>|F<sub>t</sub>|/F<sub>n</sub>−1μ or μF<sub>n</sub>>|F<sub>t</sub>|. For a stable lift, fingertip force should be applied within an angle of φ<sub>s</sub> relative to the normal reaction force (R<sub>N</sub>), where: φ<sub>s</sub> = tan<sup>−1</sup>μ<sub>s</sub>. Extending this relationship in the direction of all tangential friction force directions generates a cone of friction of half-angle φ<sub>s</sub> and cone angle ψ where: ψ = 2 φ<sub>s</sub>. <i>b)</i> As force is applied to the curved surface at a distance d<sub>LIM</sub> from the centreline of the radius, then the force is at an angle α to the surface normal. When α = φ<sub>s</sub> the force lies at the limit of the cone of friction. An increase in d results in the force lying outside the cone of friction and unstable grasp. Thus φ<sub>s</sub>, and d<sub>LIM</sub> are linked to the coefficient of static friction μ<sub>s</sub> such that an increase in μ<sub>s</sub> extends the functional area which can be grasped to achieve a stable grasp.</p
Kinematic profiles for stop and ‘on-the-fly’ prehension movements.
<p><i>Upper</i> A velocity profile typical of a stop movement: 1, the hand is in the transport phase with the wrist IRED reaching peak velocity. 2, as the hand and fingers approach the object the hand velocity drops below the threshold velocity (Vth) and remains below threshold velocity or stops for a period (T<sub>DW</sub>). 3, upon successful application of the grip, both the wrist and object markers move in unison as part of a second distinct movement. 4, movement complete – hand and object velocity tends to zero. Time to Peak Speed (tPS) is defined as the time between the wrist marker moving above Vth and achieving peak speed. Movement time is defined as the time elapsed between the wrist marker achieving Vth and the object marker achieving Vth, here represented in the stop movement scenario. <i>Lower</i> A velocity profile typical of a ‘fly-through’ movement: 1, the hand is in transport phase toward the object. 2, as the fingers contact the object, the wrist IRED velocity is maintained above the threshold velocity (Vth) as the object is gripped. 3, the hand and object continue to move in unison while the wrist IRED velocity remains above the threshold velocity. 4, movement complete, hand and object velocity tends to zero. Movement time is defined as the time elapsed between the wrist marker achieving Vth and the object marker achieving Vth, here represented in the fly-through movement scenario.</p
Shifts in gender equality and suicide: A panel study of changes over time in 87 countries
A Quality Assessment of the ARM-Net Registry Design and Data Collection
Background: Registries are important in rare disease research. The Anorectal Malformation Network (ARM-Net) registry is a well-established European patient registry collecting demographic, clinical, and functional outcome data. We assessed the quality of this registry through review of the structure, data elements, collected data, and user experience. Material and methods: Design and data elements were assessed for completeness, consistency, usefulness, accuracy, validity, and comparability. An intra- and inter-user variability study was conducted through monitoring and re-registration of patients. User experience was assessed via a questionnaire on registration, design of registry, and satisfaction. Results: We evaluated 119 data elements, of which 107 were utilized and comprised 42 string and 65 numeric elements. A minority (37.0%) of the 2278 included records had complete data, though this improved to 83.5% when follow-up elements were excluded. Intra-observer variability demonstrated 11.7% incongruence, while inter-observer variability was 14.7%. Users were predominantly pediatric surgeons and typically registered patients within 11–30 min. Users did not experience any significant difficulties with data entry and were generally satisfied with the registry, but preferred more longitudinal data and patient-reported outcomes. Conclusions: The ARM-Net registry presents one of the largest ARM cohorts. Although its collected data are valuable, they are susceptible to error and user variability. Continuous evaluations are required to maintain relevant and high-quality data and to achieve long-term sustainability. With the recommendations resulting from this study, we call for rare disease patient registries to take example and aim to continuously improve their data quality to enhance the small, but impactful, field of rare disease research. Level of Evidence: V