Does Inflexible Attention Undermine the Benefits of Cognitive Reappraisal? A Multi-method Study of Adolescents With Anxiety

Several models suggest that anxious individuals suffer from deficits in emotion regulation. However, cognitive reappraisal has shown to effectively reduce anxiety. Deficits in attentional control have been theorized as a possible underlying mechanism of emotion regulation and may moderate the association between cognitive reappraisal and anxiety. Therefore, the present study examined the moderating role of attentional control on the effects of cognitive reappraisal on anxiety symptomology via multiple methodologies in a sample of adolescents. Community dwelling adolescents (N=51) completed measures of anxiety symptoms, the habitual use of cognitive reappraisal, an attention disengagement eye tracking task, and an 8-day Ecological Momentary Assessment (EMA) protocol that measured hourly peak and current ratings of nervousness. Multiple moderation models were fit to examine study hypotheses. Contrary to expectation, neither of the hypotheses were supported and cognitive reappraisal was found to be unrelated to self-reported anxiety symptoms and ratings of nervousness in daily life. However, slower disengagement from disgusted faces significantly predicted increased anxiety symptoms. Interestingly, slower disengagement from sad faces significantly predicted less change in peak to current nervousness. Results suggest that an attention disengagement task may be used as a preventative or screening measure for those who have subthreshold levels of anxiety

Number of books at home as an indicator of socioeconomic status : Examining its extensions and their incremental validity for academic achievement

The present study investigates the incremental validity of the traditional books-at-home measure and selected extensions (i.e., number of children’s books and number of ebooks) for explaining students’ academic achievement as measured by their academic language comprehension. Using multiple linear regressions, we additionally explore the role of the source of information (i.e., whether information is given by parents or children). Based on cross-sectional data of a German sample of 2353 elementary school children from Grades 2 through 4, we found that parents’ information on the number of books and children’s books contributed to students’ academic language comprehension over and above parental occupation and education. Children’s information on the number of books did not further increase the amount of explained variance, and the effects were smaller than those for parents’ information. Yet, when investigated separately, both parents’ and children’s information on the number of books and children’s books at home predicted students’ academic language comprehension and mediated the relationship between more distal structural features of socioeconomic status (i.e., parents’ occupational status and education) and the outcome variable. No effect emerged for the number of ebooks. Our findings point to the robustness of the traditional books-at-home measure when used in parent questionnaires

Number of books at home as an indicator of socioeconomic status: Examining its extensions and their incremental validity for academic achievement

The present study investigates the incremental validity of the traditional books-at-home measure and selected extensions (i.e., number of children’s books and number of ebooks) for explaining students’ academic achievement as measured by their academic language comprehension. Using multiple linear regressions, we additionally explore the role of the source of information (i.e., whether information is given by parents or children). Based on cross-sectional data of a German sample of 2353 elementary school children from Grades 2 through 4, we found that parents’ information on the number of books and children’s books contributed to students’ academic language comprehension over and above parental occupation and education. Children’s information on the number of books did not further increase the amount of explained variance, and the effects were smaller than those for parents’ information. Yet, when investigated separately, both parents’ and children’s information on the number of books and children’s books at home predicted students’ academic language comprehension and mediated the relationship between more distal structural features of socioeconomic status (i.e., parents’ occupational status and education) and the outcome variable. No effect emerged for the number of ebooks. Our findings point to the robustness of the traditional books-at-home measure when used in parent questionnaires.Peer Reviewe

Ants inhabiting stumps on clearcuts in managed forest in western Poland

We studied ant communities living in stumps left on clearcuts. The clearcuts were located in a managed forest in western Poland. Depending on the study site, 10-80% of the stumps were inhabited by ant colonies. Lasius platythorax was the dominant of the community. We found the diameter of the stump to be positively related with the occurrence of some ant species. In general, oak and pine stumps were inhabited in a similar proportion. Formica fusca, however, showed a distinct preference for oaks. All species avoided each other with exception of F. fusca which preferred all species other than L. platythorax. We did not find the presence of red wood ants to significantly affect the occurrence of ant colonies in these stumps. The results of our investigations indicate that stumps left on clearcuts are convenient nest site for ants. Leaving stumps affects positively the growth of the L. platythorax population

The Role of −786T/C Polymorphism in the Endothelial Nitric Oxide Synthase Gene in Males with Clinical and Biochemical Features of the Metabolic Syndrome

Background. Extensive evidence, arising from models of endothelial nitric oxide synthase gene (NOS3)-knockout mice supports the role of endothelial malfunction in the pathogenesis of the metabolic syndrome (MS). Aims. The aim of this study was to evaluate the role of −786T/C polymorphism in the etiology of MS and assess previously reported interaction with cigarette smoking. Methods. Based on International Diabetes Federation 2005 criteria, we recruited randomly 152 subjects with MS and 75 subjects without MS. Results. Allelic and genotype frequencies did not differ significantly between both groups. Total cholesterol level (CHOLT) and intima-media thickness of carotid arteries were significantly higher in −786CC homozygotes, in comparison with −786TC and −786TT patients. Regarding current smoking status, −786C allele was associated with higher CHOLT than −786T allele. Conclusion. Our study indicates the putative role of −786T/C polymorphism in the development of hypercholesterolemia, in patients with MS, which might be enhanced by cigarette smoking

Lehrerurteile, soziale Herkunft der Schülerinnen und Schülern und Lernfortschritte in der Grundschule : eine länderübergreifende Perspektive

This study takes a cross-country perspective to examine whether inaccurate teacher judgements of students’ math skills correlate with student social origin and whether such bias is associated with math achievement in primary school. We focus on England, Germany, and the US because these countries differ in the teachers’ growth mindsets, accountability, the use of standardised tests, and the extent of ability grouping. The data stem from three large-scale surveys, the Millennium Cohort Study for England, the National Educational Panel Study for Germany, and the Early Childhood Longitudinal Study, Kindergarten Class of 2010–11 for the US. At the beginning of primary education, teacher judgements were not entirely consistent with student scores in standardised tests. In England and Germany, teachers underrated students with low-educated parents and overrated those with high-educated parents. In the US, no such differences were found. In all three countries, overrated (or underrated) students performed better (worse) later on. In England and, to a lesser extent, in Germany, we found evidence that biased teacher judgements contribute - over the course of primary school - to widening inequalities in value-added achievement by parental education. Such effects were negligible in the US. Our findings suggest that a cross-country perspective is essential to better understand contextual factors’ role in systematic bias in teacher judgements and its relevance for educational achievement. This study can be seen as a starting point for future research to investigate the mechanisms of such contextual effects more thoroughly

Covered with Writing... – Products on a Paper Base From the Archaeological Research at the Former Gestapo Headquarters in Anstadt Avenue in Łódź

During the archaeological research conducted in 2019 under the project “The Former Headquarters of the Gestapo and the Communist Provincial Office of Public Security in Anstadt Avenue in Łódź. Interdisciplinary Site Research” under the supervision of Dr Olgierd Ławrynowicz, an object filled with products on a paper base and bookbinding materials was found in one of the excavations. This paper attempts to clarify the chronology of paper products and to identify their type (typescripts, prints of monetary value, books, bookbinding materials, arrangement drawings, other paper products) and the material used. The visible content was identified using basic research methods and digital photographic documentation of it was made to preserve it

Antidepressant- and anxiolytic-like effects of new dual 5-HT_{1A} and 5-HT_{7} antagonists in animal models

The aim of this study was to further characterize pharmacological properties of two phenylpiperazine derivatives: 1-{2-[2-(2,6-dimethlphenoxy)ethoxy]ethyl}-4-(2-methoxyphenyl)piperazynine hydrochloride (HBK-14) and 2-[2-(2-chloro-6-methylphenoxy)ethoxy]ethyl-4-(2- methoxyphenyl)piperazynine dihydrochloride (HBK-15) in radioligand binding and functional in vitro assays as well as in vivo models. Antidepressant-like properties were investigated in the forced swim test (FST) in mice and rats. Anxiolytic-like activity was evaluated in the four-plate test in mice and elevated plus maze test (EPM) in rats. Imipramine and escitalopram were used as reference drugs in the FST, and diazepam was used as a standard anxiolytic drug in animal models of anxiety. Our results indicate that HBK-14 and HBK-15 possess high or moderate affinity for serotonergic 5-HT2, adrenergic α1, and dopaminergic D2 receptors as well as being full 5-HT1A and 5-HT7 receptor antagonists. We also present their potent antidepressant-like activity (HBK-14-FST mice: 2.5 and 5 mg/kg; FST rats: 5 mg/kg) and (HBK-15-FST mice: 1.25, 2.5 and 5 mg/kg; FST rats: 1.25 and 2.5 mg/kg). We show that HBK-14 (four-plate test: 2.5 and 5 mg/kg; EPM: 2.5 mg/kg) and HBK-15 (four-plate test: 2.5 and 5 mg/kg; EPM: 5 mg/kg) possess anxiolytic-like properties. Among the two, HBK-15 has stronger antidepressant-like properties, and HBK-14 displays greater anxiolytic-like activity. Lastly, we demonstrate the involvement of serotonergic system, particularly 5-HT1A receptor, in the antidepressant- and anxiolytic-like actions of investigated compounds

The Role of −786T/C Polymorphism in the Endothelial Nitric Oxide Synthase Gene in Males with Clinical and Biochemical Features of the Metabolic Syndrome

Background. Extensive evidence, arising from models of endothelial nitric oxide synthase gene (NOS3)-knockout mice supports the role of endothelial malfunction in the pathogenesis of the metabolic syndrome (MS). Aims. The aim of this study was to evaluate the role of −786T/C polymorphism in the etiology of MS and assess previously reported interaction with cigarette smoking. Methods. Based on International Diabetes Federation 2005 criteria, we recruited randomly 152 subjects with MS and 75 subjects without MS. Results. Allelic and genotype frequencies did not differ significantly between both groups. Total cholesterol level (CHOLT) and intima-media thickness of carotid arteries were significantly higher in −786CC homozygotes, in comparison with −786TC and −786TT patients. Regarding current smoking status, −786C allele was associated with higher CHOLT than −786T allele. Conclusion. Our study indicates the putative role of −786T/C polymorphism in the development of hypercholesterolemia, in patients with MS, which might be enhanced by cigarette smoking

Chemically homogenous compounds with antagonistic properties at all α1\alpha_{1}-adrenoceptor subtypes but not β1\beta_{1}-adrenoceptor attenuate adrenaline-induced arrhythmia in rats

Studies proved that among all α1-adrenoceptors, cardiac myocytes functionally express only α1A- and α1B-subtype. Scientists indicated that α1A-subtype blockade might be beneficial in restoring normal heart rhythm. Therefore, we aimed to determine the role of α1-adrenoceptors subtypes (i.e. α1A and α1B) in antiarrhythmic effect of six structurally similar derivatives of 2-methoxyphenylpiperazine. We compared the activity of studied compounds with carvedilol, which is β1- and α1-adrenoceptors blocker with antioxidant properties.To evaluate the affinity for adrenergic receptors, we used radioligand methods. We investigated selectivity at α1-adrenoceptors subtypes using functional bioassays. We tested antiarrhythmic activity in adrenaline-induced (20 µg/kg i.v.), calcium chloride-induced (140 and 25 mg/kg i.v.) and barium chloride-induced (32 and 10 mg/kg i.v.) arrhythmia models in rats. We also evaluated the influence of studied compounds on blood pressure in rats, as well as lipid peroxidation. All studied compounds showed high affinity towards α1-adrenoceptors but no affinity for β1 receptors. Biofunctional studies revealed that the tested compounds blocked α1A- stronger than α1B-adrenoceptors, but except for HBK-19 they antagonized α1A-adrenoceptor weaker than α1D-subtype. HBK-19 showed the greatest difference in pA2 values - it blocked α1A-adrenoceptors around sevenfold stronger than α1B subtype. All compounds showed prophylactic antiarrhythmic properties in adrenaline-induced arrhythmia, but only the activity of HBK-16, HBK-17, HBK-18 and HBK-19 (ED50=0.18-0.21) was comparable to that of carvedilol (ED50=0.36). All compounds reduced mortality in adrenaline-induced arrhythmia. HBK-16, HBK-17, HBK-18 and HBK-19 showed therapeutic antiarrhythmic properties in adrenaline-induced arrhythmia. None of the compounds showed activity in calcium chloride- or barium chloride-induced arrhythmias. HBK-16, HBK-17, HBK-18 and HBK-19 decreased heart rhythm at ED84. All compounds significantly lowered blood pressure in normotensive rats. HBK-18 showed the strongest hypotensive properties (the lowest active dose: 0.01 mg/kg). HBK-19 was the only compound in the group, which did not show hypotensive effect at antiarrhythmic doses. HBK-16, HBK-17, HBK-18, HBK-19 showed weak antioxidant properties.Our results indicate that the studied 2-methoxyphenylpiperazine derivatives that possessed stronger α1A-adrenolytic properties (i.e. HBK-16, HBK-17, HBK-18 and HBK-19) were the most compounds in adrenaline-induced arrhythmia. Thus, we suggest that the potent blockade of α1A-receptor subtype is essential to attenuate adrenaline-induced arrhythmia