Oil Displacement Efficiency and Performance Evaluation of Composite Ion Profile Control Agents Prepared with Oilfield Sewage

According to the demand of development in Daqing oil field, in order to reduce sewage discharge and save clean water, most of the polymer injection stations have switched to polymer solution diluted by sewage. Considering the present development trend of the oil field and requirement in terms of cost control, we should further deepen the research of formulas for all kinds of chemical sewage. Performance evaluating experiments on the long-term stability, the anti-shear property, the compatibility with initial rock debris and alkali ternary combination system of profile control agents, as well as the test for the efficiency of core displacement physical simulation of profile control and oil displacement evaluation are carried in this paper, which are intended for the composite ion profile control system that are prepared with oilfield sewage. In this paper, the long-term stable composite ion profile control agents formular prepared with oilfield sewage have been determined; the profile control effect of composite ion profile control agents prepared with sewage for cores with different permeability have been presented, and the rules of composite ion profile control agents prepared with sewage on oil displacement effect at different injection time and injection rate have been studied.Research shows that the long-term heat stability, anti-shear property, compatibility with initial rock debris and alkali ternary combination system of composite ion profile control agents prepared with sewage are well, as well as the core plugging effect and anti-corrosion performance. Oil displacement results are obviously different when profile control agents are injected at different time. Injecting profile control agents before polymer flooding works best, medium term secondly, and late stage thirdly. At the same time, the enhanced recovery rate increases with increased profile control agents injection. While the increase of enhanced oil recovery rate becomes slower when the profile control agents injection reach 0.1 PV. After profile control measures are taken, the average injection pressure and starting pressure has risen respectively by 2.7 Mpa and 2.6 Mpa; the water absorbing capacity of high permeable formation has been under control; the water absorbing capacity of low permeable formation has been strengthened; the absorbing water thickness of all wells have been increased; the breakthrough of flooded fluid in certain direction have been solved, which leads to more even polymer forward.Key words: Oil displacement effect evaluation; Performance evaluation; Composite ion profile control agents; Oil produced water preparing polymer

mmBody Benchmark: 3D Body Reconstruction Dataset and Analysis for Millimeter Wave Radar

Millimeter Wave (mmWave) Radar is gaining popularity as it can work in adverse environments like smoke, rain, snow, poor lighting, etc. Prior work has explored the possibility of reconstructing 3D skeletons or meshes from the noisy and sparse mmWave Radar signals. However, it is unclear how accurately we can reconstruct the 3D body from the mmWave signals across scenes and how it performs compared with cameras, which are important aspects needed to be considered when either using mmWave radars alone or combining them with cameras. To answer these questions, an automatic 3D body annotation system is first designed and built up with multiple sensors to collect a large-scale dataset. The dataset consists of synchronized and calibrated mmWave radar point clouds and RGB(D) images in different scenes and skeleton/mesh annotations for humans in the scenes. With this dataset, we train state-of-the-art methods with inputs from different sensors and test them in various scenarios. The results demonstrate that 1) despite the noise and sparsity of the generated point clouds, the mmWave radar can achieve better reconstruction accuracy than the RGB camera but worse than the depth camera; 2) the reconstruction from the mmWave radar is affected by adverse weather conditions moderately while the RGB(D) camera is severely affected. Further, analysis of the dataset and the results shadow insights on improving the reconstruction from the mmWave radar and the combination of signals from different sensors.Comment: ACM Multimedia 2022, Project Page: https://chen3110.github.io/mmbody/index.htm

Prediction of regulatory motifs from human Chip-sequencing data using a deep learning framework

The identification of transcription factor binding sites and cis-regulatory motifs is a frontier whereupon the rules governing protein-DNA binding are being revealed. Here, we developed a new method (DEep Sequence and Shape mOtif or DESSO) for cis-regulatory motif prediction using deep neural networks and the binomial distribution model. DESSO outperformed existing tools, including DeepBind, in predicting motifs in 690 human ENCODE ChIP-sequencing datasets. Furthermore, the deep-learning framework of DESSO expanded motif discovery beyond the state-of-the-art by allowing the identification of known and new protein-protein-DNA tethering interactions in human transcription factors (TFs). Specifically, 61 putative tethering interactions were identified among the 100 TFs expressed in the K562 cell line. In this work, the power of DESSO was further expanded by integrating the detection of DNA shape features. We found that shape information has strong predictive power for TF-DNA binding and provides new putative shape motif information for human TFs. Thus, DESSO improves in the identification and structural analysis of TF binding sites, by integrating the complexities of DNA binding into a deep-learning framework

Irisin attenuates pyroptosis in high glucose-induced pancreatic beta cells via the miR-133a-3p/FOXO1 axis

Introduction: Irisin is closely related to type 2 diabetes mellitus (T2DM) and other metabolic diseases. It can improve the homeostasis of T2DM. MiR-133a-3p is decreased in the peripheral blood of patients with T2DM. Forkhead box protein O1 (FOXO1) is widely expressed in beta-cells and affects the occurrence of diabetes through transcriptional regulation and signalling pathway regulation. Material and methods: The miR-133a-3p inhibitor was constructed to verify the effect of irisin on pyroptosis through miR-133a-3p. Next, we predicted the presence of targeted binding sequences between FOXO1 and miR-133a-3p by bioinformatics software, which was then confirmed with a double fluorescence assay. Finally, the FOXO1 overexpression vector was used to further verify the effect of irisin through the miR-133a-3p/FOXO1 axis. Results: We first observed that irisin inhibited the protein levels of N-terminal gasdermin D (GSDMD-N) and cleaved caspase-1 and the secretion of interleukins (IL): IL-1beta and IL-18 in Min6 cells treated with high glucoes (HG). Irisin inhibited pyroptosis of Min6 cells treated with HG by reinforcing miR-133a-3p. Then, FOXO1 was validated to be the target gene of miR-133a. Both miR-133a-3p inhibitor and overexpression of FOXO1 restrained the force of irisin on pyroptosis in HG-induced Min6 cells. Conclusion: We explored the protective effect of irisin on HG-induced pyroptosis of islet b-cells in vitro and explained its mechanism of inhibiting pyroptosis through the miR-133a-3p/FOXO1 axis, to provide a theoretical basis for finding new molecular targets to delay beta-cell failure and the treatment of T2DM

The Aroma Composition of Baby Ginger Paocai

The purpose of this study was to analyze the volatile compounds in baby ginger paocai and the fresh baby ginger and identify the key aroma components that contribute to the flavor of baby ginger paocai. A total of 86 volatile compounds from the two baby ginger samples were quantified; these compounds were extracted by headspace solid-phase microextraction (HS-SPME) and analyzed by gas chromatography–mass spectrometry (GC-MS). The aroma composition of baby ginger paocai was different from that of fresh baby ginger. Baby ginger paocai was characterized by the presence of aroma-active compounds which varied in concentration from 0.03 to 28.14%. Geranyl acetate was the aroma component with the highest relative content in baby ginger paocai. β-myrcene, eucalyptol, trans-β-ocimene, Z-ocimene, linalool, decanal, cis-citral, geraniol, geranyl acetate, curcumene, and β-bisabolene contributed to the overall aroma of the product of baby ginger paocai which had gone through a moderate fermentation process

A Survey on Transferability of Adversarial Examples across Deep Neural Networks

The emergence of Deep Neural Networks (DNNs) has revolutionized various domains, enabling the resolution of complex tasks spanning image recognition, natural language processing, and scientific problem-solving. However, this progress has also exposed a concerning vulnerability: adversarial examples. These crafted inputs, imperceptible to humans, can manipulate machine learning models into making erroneous predictions, raising concerns for safety-critical applications. An intriguing property of this phenomenon is the transferability of adversarial examples, where perturbations crafted for one model can deceive another, often with a different architecture. This intriguing property enables "black-box" attacks, circumventing the need for detailed knowledge of the target model. This survey explores the landscape of the adversarial transferability of adversarial examples. We categorize existing methodologies to enhance adversarial transferability and discuss the fundamental principles guiding each approach. While the predominant body of research primarily concentrates on image classification, we also extend our discussion to encompass other vision tasks and beyond. Challenges and future prospects are discussed, highlighting the importance of fortifying DNNs against adversarial vulnerabilities in an evolving landscape

Exploring the differential stages of the pigment metabolism by pre-harvest bagging and post-harvest ethylene de-greening of Eureka lemon peel

Pre-harvest bagging or post-harvest ethylene treatments on lemons are commonly applied to change the surface color from green to favorable yellow. In this study, the differential mechanisms of the pigment metabolism by the two treatments were investigated by pigments contents and related genetic expression. The results showed that both treatments reduced the number of chloroplasts and the content of chlorophyll. The differential expression of PSY1 and PSY2 were observed, causing the different accumulation of the main carotenoid phytoene content. The differential expression of NYC resulted in altered contents of chlorophyll a and chlorophyll b, and further led to the difference in a* value. More interestingly, the degradation of chlorophyll uncovered the color of carotenoids, leading to the color changed from green to yellow

Aggregation-Induced Emission (AIE), Life and Health

Light has profoundly impacted modern medicine and healthcare, with numerous luminescent agents and imaging techniques currently being used to assess health and treat diseases. As an emerging concept in luminescence, aggregation-induced emission (AIE) has shown great potential in biological applications due to its advantages in terms of brightness, biocompatibility, photostability, and positive correlation with concentration. This review provides a comprehensive summary of AIE luminogens applied in imaging of biological structure and dynamic physiological processes, disease diagnosis and treatment, and detection and monitoring of specific analytes, followed by representative works. Discussions on critical issues and perspectives on future directions are also included. This review aims to stimulate the interest of researchers from different fields, including chemistry, biology, materials science, medicine, etc., thus promoting the development of AIE in the fields of life and health

Concentration effects in solid-state CD spectra of chiral atropisomeric compounds

Atropisomerism is one of the basic concepts in stereochemistry. Chiral crystals of stereochemically labile atropisomers that originated from Mirror Symmetry Breaking (MSB) can only be characterized by solid-state chiroptical techniques. Herein, solid-state circular dichroism and UV-Vis spectra of six atropisomeric compounds (most of them were obtained from MSB) have been studied. A concentration effect including a wavelength shift and inverse concentration-dependence has been found and preliminarily explained by the absorption flattening effect, scattering effect and the torsion in the molecular structures.National Natural Science Foundation of China[20973136, 20974028, 20732004]; Natural Science Foundation of Fujian Province[2010J01048

Dropping Shock Characteristics of the Suspension Cushioning System with Critical Components

Dimensionless dropping shock dynamic equations of suspension nonlinear packaging system with critical components were obtained. The numerical results of shock response were gained using Runge-Kutta method. To evaluate the dropping shock characteristics of critical components, the dropping damage boundary curve was established, where the system parameter and the dimensionless shock velocity were selected as two coordinate parameters. Then, the frequency ratio and the system damping ratio were taken as third basic parameters of the dropping damage boundary surface, respectively. To study dynamic properties of the suspension system with critical components, the shock response acceleration, shock response displacements, and dropping damage boundary were analyzed. Based on the numerical results, the effects of the relevant parameters on dropping shock response and damage boundary of critical component were investigated. It is demonstrated that both a higher frequency ratio and a system damping ratio in the specific range can exert a positive effect on the product protection and should be selected in design process of the suspension system. Furthermore, with the decrease of suspension angle, the acceleration response peak decreases, the displacement response peak increases, and the safety zone enlarges