154 research outputs found

    Russian Language for Specific Purposes: Business Communication for Bilingual Learners. From General Concepts to Practical Applications

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    The study is focused on revealing and analysis of external influences that affect the process of teaching the Russian language for specific purposes - business/professional communication to bilingual learners. The analysis is correlated with the description of external factors that cause a shift of emphasis from teaching the language of profession to teaching business communication. This comprehensive analysis makes it possible to build a uniform teaching course model based on a holistic approach. The study defines the general strategy of training, formulates tasks and outlines approaches to their solution, as well as delineates the contours of a branched out multi-component practical training course

    From correlation to causation: the cruciality of a collectivity in the context of collective action

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    This paper discusses a longitudinal field study on collective action which aims to move beyond student samples and enhance mundane realism. First we provide a historical overview of the literature on the what (i.e., antecedents of collective action) and the how (i.e., the methods employed) of the social psychology of protest. This historical overview is substantiated with meta-analytical evidence on how these antecedents and methods changed over time. After the historical overview, we provide an empirical illustration of a longitudinal field study in a natural setting―a newly-built Dutch neighbourhood. We assessed changes in informal embeddedness, efficacy, identification, emotions, and grievances over time. Between t0 and t1 the residents protested against the plan to allow a mosque to carrying out their services in a community building in the neighbourhood. We examined the antecedents of protest before [t0] and after [t1] the protests, and whether residents participated or not. We show how a larger social network functions as a catalyst in steering protest participation. Our longitudinal field study replicates basic findings from experimental and survey research. However, it also shows that one antecedent in particular, which is hard to manipulate in the lab (i.e., the size of someone’s social network), proved to be of great importance. We suggest that in overcoming our most pertinent challenge―causality―we should not only remain in our laboratories but also go out and examine real-life situations with people situated in real-life social networks

    Application of probability methods to research of one type of exotic options in diffusion model (B, S)- of the financial market

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    The decision of optimum hedging problem for the European options of purchase and sale of the exotic type when possible payments on options are limited by the set value is resulted. The formulas defining costs of options and also evolution in time of portfolios and capitals, i. e. hedging strategy and corresponding to them are obtained. Some properties of decisions are investigated

    The Famenian reservoir limestones on core petrophysical and electron spin resonance data (Southern slope of South-Tatarian Arc)

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    This paper presents core data on the composition and reservoir properties of the Famenian carbonate rocks in typical well section on the southern slope of South-Tatarian Arc. The core data include structures, minerals, reservoir properties measurements from previous studies and geochemical signs, just received by method of electron spin resonance (ESR). Investigated intervals of 16 and 6 m thicknesses belong to the Famenian stage. The thickest interval is composed of grainstones and packstones. The second interval is composed of mainly packstones. The granulated fossils predominate in the studied limestones. Porous space is controlled by primary structure and also by leaching processes, secondary calcite mineralization and stylolites. The interval of 16 m concludes four layers on thin sections data and reservoir properties. The interval of 6 m belongs to one layer. ESR data have been obtained on 22 samples collected with step 0.6-1.2 m along the section. ESR spectra are characterized by narrow lines, pointing on marine genesis of carbonates. Paramagnetic centers of Mn2+ and SO2- have been observed as typical labels of rocks due by processes of carbonate sedimentation. A symbate behavior of Mn2+ and SO2- contents along the section correlates with reservoir characteristics increasing. A diverse behavior of Mn2+ and SO2- contents corresponds to reservoir characteristics decreasing. It can be explained by the unaltered carbonates in the first case and the altered carbonates in the second case because of the leaching, secondary crystallization, adding of the paramagnetic ions and redistribution of paramagnetic centers in new formed mineral phases

    The Tournesian reservoir limestones on core petrophysical and geochemical data (Southern slope of South-Tatarian Arc)

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    This paper presents core data on the composition and reservoir properties of the Tourneisian carbonate rocks in typical well section on the southern slope of South-Tatarian Arc. The core data include structures, minerals, reservoir properties measurements from previous studies and geochemical signs, just received by method of electron spin resonance (ESR). Investigated interval of 12 m thickness belongs to an upper part of the Tourneisian stage. It is composed of two layers: upper grainstone layer (5 m) and lower packstone layer (7 m). The granulated fossils predominate in the studied limestones. A porous space is controlled by primary structures and also by leaching processes, a secondary calcite mineralization and stylolites. ESR data have been obtained on 21 samples collected with a step 0.4-0.6 m along the section. ESR spectra are characterized by narrow lines, pointing on a marine genesis of the carbonates. Paramagnetic centers of Mn 2+ and SO 2- have been observed as typical features of the rocks due by primary processes of carbonate sedimentation. A spatial distribution of limestones types, its geochemical and reservoir signatures is explained by the sedimentary succession of progradation type. The calcite mineralization and a distribution of Mn 2+ and SO 2- paramagnetic ions have been determined along the section profile simultaneously with reservoir zoning due by facies and a history of hydrocarbons

    ΠœΠ•Π’ΠžΠ”Π« ΠžΠ¦Π•ΠΠšΠ˜ ЦВЕВА Π’Π˜Π. ΠžΠ‘Π—ΠžΠ 

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    Current article discusses methods for evaluating the color of wines based on the principles of visual tasting and spectrophotometric measurement. A particular attention has been paid to the chromatic profile of wines including the color intensity (I) and the color tint (T), the proportion of red coloration (dA), the contributions of red (D420), yellow (D520) and blue (D620) colors to the total wine color, the color hue (tg Ξ±), and the yellowness index (G). The existing approaches to the instrumental color assessment are largely based on the determination of the estimated indicators and considering the optical densities at the wavelengths of 420, 520 and 620 nm. It has been demonstrated that the main weaknesses of these methods are their modest informative value, the complexity of application and the inconsistency of the interpretation. The illumination and human perception have a significant impact on the visual assessment of the wine, while the lack of the standard color classification, terminology and definitions make it impossible to compare the results obtained in various studies. An alternative method to define and describe the color of food products, including wines, is a three-chromatic model CIELab, which can reproduce not only the color using a common set of coordinates with the help of a color converter, but also can assess the colorimetric difference between the samples. This is of interest, since the application of the system described above will help standardize the results of the optical and sensory analysis methods. The practical application of this method may be promising from the viewpoint of visual tasting indicators’ standardization and the reproduction of products with declared characteristics.Β Β Β Β Β Β Β Β  Keywords: wine, chromatic properties, color intensity, color tonality, CIELab spaceDOI: http://dx.doi.org/10.15826/analitika.2019.23.2.003(Russian)N.S. Anikina, S.N. Cherviak, N.V. GnilomedovaΒ All-Russian National Research Institute of Viniculture and Winemaking "Magarach" of RAS , Kirova Str, 31, Yalta, 298600, Republic of Crimea, Russian FederationРассмотрСны ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹ ΠΎΡ†Π΅Π½ΠΊΠΈ Ρ†Π²Π΅Ρ‚Π° Π²ΠΈΠ½ Π½Π° основС ΠΏΡ€ΠΈΠ½Ρ†ΠΈΠΏΠΎΠ² органолСптичСского Π°Π½Π°Π»ΠΈΠ·Π° ΠΈ оптичСской спСктроскопии. ОсобоС Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ ΡƒΠ΄Π΅Π»Π΅Π½ΠΎ показатСлям хроматичСских характСристик Π²ΠΈΠ½: ΠΎΡ‚Ρ‚Π΅Π½ΠΎΠΊ (T) ΠΈ ΠΈΠ½Ρ‚Π΅Π½ΡΠΈΠ²Π½ΠΎΡΡ‚ΡŒ (I) Ρ†Π²Π΅Ρ‚Π°, доля красной окраски (dA), Π΄ΠΎΠ»ΠΈ красных (D420), ΠΆΠ΅Π»Ρ‚Ρ‹Ρ… (D520) ΠΈ синих (D620) ΠΏΠΈΠ³ΠΌΠ΅Π½Ρ‚ΠΎΠ², ΡƒΠ³Π»ΠΎΠ²ΠΎΠΉ ΠΎΡ‚Ρ‚Π΅Π½ΠΎΠΊ Ρ†Π²Π΅Ρ‚Π° (tg Ξ±), ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΡŒ ΠΆΠ΅Π»Ρ‚ΠΈΠ·Π½Ρ‹ (G). Π‘ΡƒΡ‰Π΅ΡΡ‚Π²ΡƒΡŽΡ‰ΠΈΠ΅ ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Ρ‹ ΠΊ ΠΈΠ½ΡΡ‚Ρ€ΡƒΠΌΠ΅Π½Ρ‚Π°Π»ΡŒΠ½ΠΎΠΉ ΠΎΡ†Π΅Π½ΠΊΠ΅ Ρ†Π²Π΅Ρ‚Π° прСимущСствСнно ΠΎΡΠ½ΠΎΠ²Ρ‹Π²Π°ΡŽΡ‚ΡΡ Π½Π° ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΠΈ расчСтных ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»Π΅ΠΉ с ΡƒΡ‡Π΅Ρ‚ΠΎΠΌ Π·Π½Π°Ρ‡Π΅Π½ΠΈΠΉ оптичСской плотности ΠΏΡ€ΠΈ Π΄Π»ΠΈΠ½Π°Ρ… Π²ΠΎΠ»Π½ 420, 520 ΠΈ 620 Π½ΠΌ. Показано, Ρ‡Ρ‚ΠΎ основными ΠΈΡ… нСдостатками ΡΠ²Π»ΡΡŽΡ‚ΡΡ ΠΌΠ°Π»ΠΎΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ, ΡΠ»ΠΎΠΆΠ½ΠΎΡΡ‚ΡŒ ΠΏΡ€ΠΈΠΊΠ»Π°Π΄Π½ΠΎΠ³ΠΎ использования, ΠΏΡ€ΠΎΡ‚ΠΈΠ²ΠΎΡ€Π΅Ρ‡ΠΈΠ²ΠΎΡΡ‚ΡŒ Π² ΠΈΠ½Ρ‚Π΅Ρ€ΠΏΡ€Π΅Ρ‚Π°Ρ†ΠΈΠΈ. Π—Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ΅ влияниС Π½Π° Π²ΠΈΠ·ΡƒΠ°Π»ΡŒΠ½ΡƒΡŽ ΠΎΡ†Π΅Π½ΠΊΡƒ Π²ΠΈΠ½ ΠΎΠΊΠ°Π·Ρ‹Π²Π°ΡŽΡ‚ освСщСниС ΠΈ восприятиС Ρ‡Π΅Π»ΠΎΠ²Π΅ΠΊΠ°; отсутствиС общСпринятой классификации Ρ†Π²Π΅Ρ‚Π°, пСрСчня Ρ‚Π΅Ρ€ΠΌΠΈΠ½ΠΎΠ² ΠΈ понятий для Π΅Π³ΠΎ описания Π½Π΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡŽΡ‚ ΡΠΎΠΏΠΎΡΡ‚Π°Π²Π»ΡΡ‚ΡŒ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹, ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Π΅ Π² Ρ€Π°Π·Π½Ρ‹Ρ… исслСдованиях. Одним ΠΈΠ· Π°Π»ΡŒΡ‚Π΅Ρ€Π½Π°Ρ‚ΠΈΠ²Π½Ρ‹Ρ… способов характСристики ΠΈ описания Ρ†Π²Π΅Ρ‚Π° ΠΏΠΈΡ‰Π΅Π²Ρ‹Ρ… ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ‚ΠΎΠ², Π² Ρ‚ΠΎΠΌ числС Π²ΠΈΠ½, являСтся трихроматичСская модСль CIELab, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡŽΡ‰Π°Ρ Π½Π΅ Ρ‚ΠΎΠ»ΡŒΠΊΠΎ Π²ΠΎΡΠΏΡ€ΠΎΠΈΠ·Π²ΠΎΠ΄ΠΈΡ‚ΡŒ Ρ†Π²Π΅Ρ‚ ΠΏΠΎ установлСнным ΠΊΠΎΠΎΡ€Π΄ΠΈΠ½Π°Ρ‚Π°ΠΌ с ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ ΠΊΠΎΠ½Π²Π΅Ρ€Ρ‚Π΅Ρ€Π° Ρ†Π²Π΅Ρ‚Π°, Π½ΠΎ ΠΈ ΠΎΡ†Π΅Π½ΠΈΠ²Π°Ρ‚ΡŒ ΠΊΠΎΠ»ΠΎΡ€ΠΈΠΌΠ΅Ρ‚Ρ€ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ Ρ€Π°Π·Π½ΠΈΡ†Ρƒ ΠΌΠ΅ΠΆΠ΄Ρƒ ΠΎΠ±Ρ€Π°Π·Ρ†Π°ΠΌΠΈ. Π­Ρ‚ΠΎ прСдставляСт интСрСс, Ρ‚Π°ΠΊ ΠΊΠ°ΠΊ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ Π΄Π°Π½Π½ΠΎΠΉ систСмы ΠΏΠΎΠΌΠΎΠΆΠ΅Ρ‚ ΡƒΠ½ΠΈΡ„ΠΈΡ†ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ оптичСского ΠΈ органолСптичСского Π°Π½Π°Π»ΠΈΠ·ΠΎΠ². ΠŸΡ€Π°ΠΊΡ‚ΠΈΡ‡Π΅ΡΠΊΠΎΠ΅ использованиС ΠΌΠ΅Ρ‚ΠΎΠ΄Π° ΠΌΠΎΠΆΠ΅Ρ‚ Π±Ρ‹Ρ‚ΡŒ пСрспСктивным с Ρ‚ΠΎΡ‡ΠΊΠΈ зрСния стандартизации органолСптичСских ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»Π΅ΠΉ ΠΈ воспроизвСдСния ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ†ΠΈΠΈ с заявлСнными характСристиками.ΠšΠ»ΡŽΡ‡Π΅Π²Ρ‹Π΅ слова: Π²ΠΈΠ½ΠΎ, оптичСскиС ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ, ΠΈΠ½Ρ‚Π΅Π½ΡΠΈΠ²Π½ΠΎΡΡ‚ΡŒ ΠΈ ΠΎΡ‚Ρ‚Π΅Π½ΠΎΠΊ Ρ†Π²Π΅Ρ‚Π°, модСль CIELabDOI: http://dx.doi.org/10.15826/analitika.2019.23.2.00

    Reação adaptativa do sistema simpÑtico de adrenalina de meninas em atividade física

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    The study of the functional state of the sympatho-adrenal system in girls of 11-16 years old undergoing graduated physical activity was performed on the basis of excretion rates of epinephrine, norepinephrine, dopamine and DOPA. As a functional test, a graduated cycloergometric load of 50% of the individually determined PWC170 was used. The results obtained made it possible to establish the heterochronic nature of the maturation of the hormonal and mediator links of the sympathetic adrenal system. The highest reactivity of the adrenal link of SAS is observed in girls of 12 years old, the lowest – in senior schoolgirls (15-16 years old). In girls of 12-13 years old, the reaction of urgent adaptation to the graduated physical activity is carried out against a background of high excretion of epinephrine (E), norepinephrine (NE), but without sufficient replenishment of the reserve capabilities of SAS, which is confirmed by minimal shifts in the excretion of dopamine (DA) and DOPA in these age groups. At 14-16 years, moderate shifts of E and NE as a reaction to activity are noted against the background of a significant increase in the excretion of precursors, which characterizes the SAS response to the functional test as more saving, with increasing reserve capacities.El estudio del estado funcional del sistema simpato-adrenal en niΓ±as de 11-16 aΓ±os sometidas a actividad fΓ­sica graduada se realizΓ³ sobre la base de las tasas de excreciΓ³n de epinefrina, norepinefrina, dopamina y DOPA. Como prueba funcional, se utilizΓ³ una carga cicloergomΓ©trica graduada del 50% de la PWC170 determinada individualmente. Los resultados obtenidos permitieron establecer la naturaleza heterΓ³crona de la maduraciΓ³n de los enlaces hormonales y mediadores del sistema adrenal simpΓ‘tico. La mayor reactividad del enlace suprarrenal de SAS se observa en niΓ±as de 12 aΓ±os, la mΓ‘s baja - en niΓ±as de escuela secundaria (15-16 aΓ±os). En niΓ±as de 12-13 aΓ±os de edad, la reacciΓ³n de adaptaciΓ³n urgente a la actividad fΓ­sica gradual se lleva a cabo en un contexto de alta excreciΓ³n de epinefrina (E), norepinefrina (NE), pero sin un reabastecimiento suficiente de las capacidades de reserva de SAS. que se confirma por cambios mΓ­nimos en la excreciΓ³n de dopamina (DA) y DOPA en estos grupos de edad. A los 14-16 aΓ±os, se observan cambios moderados de E y NE como reacciΓ³n a la actividad en el contexto de un aumento significativo en la excreciΓ³n de precursores, que caracteriza la respuesta SAS a la prueba funcional como mΓ‘s ahorro, con el aumento de la capacidad de reserva.O estudo do estado funcional das raparigas do sistema simpΓ‘tico-envelhecido 11-16 anos, submetidos a actividade fΓ­sica realizada classificados com base em taxas de excreção de epinefrina, norepinefrina, dopamina e DOPA. Como teste funcional, utilizou-se uma carga cicloergomΓ©trica graduada de 50% do PWC170 individualmente determinado. Os resultados obtidos permitiram estabelecer a natureza heterocrΓ΄nica da maturação dos laΓ§os hormonais e mediadores do sistema adrenal simpΓ‘tico. A reatividade mais alta do elo adrenal de SAS observa-se em meninas de 12 anos, o mais baixo - em meninas de escola secundΓ‘ria (15-16 anos). Em raparigas com idades entre 12-13, reacção urgente de adaptação gradual da actividade fΓ­sica ocorre em um contexto de elevada excreção de adrenalina (E), norepinefrina (NE), mas sem capacidades de reabastecimento suficientes Reserva SAS. o que Γ© confirmado por alteraçáes mΓ­nimas na excreção de dopamina (DA) e DOPA nestes grupos etΓ‘rios. Aos 14-16 anos, E e NE variaçáes moderadas em resposta Γ  actividade no contexto de um aumento significativo da excreção de precursores, o que caracteriza a resposta SAS para um teste funcional, mais economia, com o aumento observado a capacidade de reserva

    Eta-mesic nuclei in relativistic mean-field theory

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    With the eta-nucleon (eta N) interaction Lagrangian deduced from chiral perturbation theory, we study the possible eta-mesic nuclei in the framework of relativistic mean-field theory. The eta single-particle energies are sensitive to the eta N scattering length, and increase monotonically with the nucleon number A. If the scattering length is in the range of a^{eta N}=0.75-1.05 fm and the imaginary potential V_{0}-15 MeV, some discrete states of C, O and Ne eta bound states should be identified in experiments. However, when the scattering length a^{eta N} 30 MeV, no discrete eta meson bound states could be observed in experiments.Comment: 6 page

    Dynamics of hormones influencing the power exchange at women with obesity at decrease in weight of the body

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    Work purpose: to study level of hormones influencing appetite and a power exchange at women with obesity initially and after decrease in weight of a body against reception sibutramini. Materials and methods: in research 56 women are included in middle age 42,9 (36,8; 49,3) years, IMT 34,6 (29,8; 37,3) kg/sq.m. To all patients clinical, laboratory and tool examination was conducted. Hormonal research, included: definition serotonini, leptini, ghrelini, endotelina-1, growth hormone. Results: at women with obesity the giperleptinemiya, the raised level serotonini, endotelina-1 is revealed. Decrease in weight of a body against reception sibutramini was accompanied by decrease in level leptin, ghrelin, endotelina-1, serotonin. Conclusions: in patients with obesity have significantly increased levels of leptin, serotonin, ghrelin compared with women of normal weight. Weight reduction of 5% from initial led to a significant improvement in levels of endothelin-1, adiponectin. The use of sibutramine do not have a negative impact on the level of endothelin-1 and adiponectin and more effectively in patients with a BUI of less than 35 kg/m2. Slow weight loss is associated with high levels of leptin, ghrelin, serotonin.ЦСль Ρ€Π°Π±ΠΎΡ‚Ρ‹: ΠΈΠ·ΡƒΡ‡ΠΈΡ‚ΡŒ ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ Π³ΠΎΡ€ΠΌΠΎΠ½ΠΎΠ², Π²Π»ΠΈΡΡŽΡ‰ΠΈΡ… Π½Π° Π°ΠΏΠΏΠ΅Ρ‚ΠΈΡ‚ ΠΈ энСргообмСн, Ρƒ ΠΆΠ΅Π½Ρ‰ΠΈΠ½ с ΠΎΠΆΠΈΡ€Π΅Π½ΠΈΠ΅ΠΌ исходно ΠΈ послС сниТСния массы Ρ‚Π΅Π»Π° Π½Π° Ρ„ΠΎΠ½Π΅ ΠΏΡ€ΠΈΠ΅ΠΌΠ° сибутрамина. ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹: Π² исслСдованиС Π²ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΎ 56 ΠΆΠ΅Π½Ρ‰ΠΈΠ½ Π² возрастС 42,9 (36,8;49,3) Π»Π΅Ρ‚, с ИМВ 34,6 (29,8:37,3) ΠΊΠ³/ΠΌ2. ВсСм ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΊΠ°ΠΌ ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΎΡΡŒ клиничСскоС, Π»Π°Π±ΠΎΡ€Π°Ρ‚ΠΎΡ€Π½ΠΎΠ΅ ΠΈ ΠΈΠ½ΡΡ‚Ρ€ΡƒΠΌΠ΅Π½Ρ‚Π°Π»ΡŒΠ½ΠΎΠ΅ обслСдованиС. Π“ΠΎΡ€ΠΌΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ΅ исслСдованиС Π²ΠΊΠ»ΡŽΡ‡Π°Π»ΠΎ ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ сСротонина, Π»Π΅ΠΏΡ‚ΠΈΠ½Π°, Π³Ρ€Π΅Π»ΠΈΠ½Π°, эндотСлина-1, Π³ΠΎΡ€ΠΌΠΎΠ½Π° роста. Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹: Ρƒ ΠΆΠ΅Π½Ρ‰ΠΈΠ½ с ΠΎΠΆΠΈΡ€Π΅Π½ΠΈΠ΅ΠΌ выявлСна гипСрлСптинСмия, ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½Π½Ρ‹ΠΉ ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ сСротонина, эндотСлина-1. УмСньшСниС массы Ρ‚Π΅Π»Π° Π½Π° Ρ„ΠΎΠ½Π΅ ΠΏΡ€ΠΈΠ΅ΠΌΠ° сибутрамина ΡΠΎΠΏΡ€ΠΎΠ²ΠΎΠΆΠ΄Π°Π»ΠΎΡΡŒ сниТСниСм уровня Π»Π΅ΠΏΡ‚ΠΈΠ½Π°, Π³Ρ€Π΅Π»ΠΈΠ½Π°, эндотСлина-1, сСротонина. Π’Ρ‹Π²ΠΎΠ΄Ρ‹: Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ с ΠΎΠΆΠΈΡ€Π΅Π½ΠΈΠ΅ΠΌ ΠΈΠΌΠ΅ΡŽΡ‚ΡΡ Π·Π½Π°Ρ‡ΠΈΠΌΠΎ ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½Π½Ρ‹Π΅ ΡƒΡ€ΠΎΠ²Π½ΠΈ Π»Π΅ΠΏΡ‚ΠΈΠ½Π°, сСротонина, Π³Ρ€Π΅Π»ΠΈΠ½Π° ΠΏΠΎ ΡΡ€Π°Π²Π½Π΅Π½ΠΈΡŽ с ΠΆΠ΅Π½Ρ‰ΠΈΠ½Π°ΠΌΠΈ Π½ΠΎΡ€ΠΌΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ вСса. УмСньшСниС вСса Π½Π° 5% ΠΎΡ‚ исходного ΠΏΡ€ΠΈΠ²Π΅Π»ΠΎ ΠΊ достовСрному ΡƒΠ»ΡƒΡ‡ΡˆΠ΅Π½ΠΈΡŽ ΡƒΡ€ΠΎΠ²Π½Π΅ΠΉ эндотСлина-1, Π°Π΄ΠΈΠΏΠΎΠ½Π΅ΠΊΡ‚ΠΈΠ½Π°. ΠŸΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ сибутрамина Π½Π΅ ΠΎΠΊΠ°Π·Ρ‹Π²Π°Π΅Ρ‚ Π½Π΅Π³Π°Ρ‚ΠΈΠ²Π½ΠΎΠ³ΠΎ влияния Π½Π° ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ эндотСлина-1 ΠΈ Π°Π΄ΠΈΠΏΠΎΠ½Π΅ΠΊΡ‚ΠΈΠ½Π° ΠΈ Π±ΠΎΠ»Π΅Π΅ эффСктивно Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ с ИМВ ΠΌΠ΅Π½Π΅Π΅ 35 ΠΊΠ³/ΠΌ2. МСдлСнноС сниТСниС массы Ρ‚Π΅Π»Π° связано с высоким ΡƒΡ€ΠΎΠ²Π½Π΅ΠΌ Π»Π΅ΠΏΡ‚ΠΈΠ½Π°, Π³Ρ€Π΅Π»ΠΈΠ½Π°, сСротонина

    Effect of Neuropeptide Y on Action Potential Generation in Working Cardiomyocytes of the Right Atrium in Rat Heart

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    Β© 2018, Springer Science+Business Media, LLC, part of Springer Nature. We studied the effect of neuropeptide Y in concentrations of 10β€”8-10β€”6 M on electrical activity of adult rat right atrial cardiomyocytes with preserved spontaneous activity. Neuropeptide Y was found to modulate the amplitude-time parameters of action potential: in concentrations of 10β€”7 and 10β€”6 M it reduced the membrane potential, increased the amplitude of action potential and duration of the repolarization phase, and reduced the frequency of action potential generation. In concentration of 10β€”6 M, neuropeptide Y produced stronger effect on the analyzed parameters, while in concentration of 10β€”8 M it produced no significant changes
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