1,785 research outputs found

    Bayesian Sequential Track Formation

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    This paper presents a theoretical framework for track building in multiple-target scenarios from the Bayesian point of view. It is assumed that the number of targets is fixed and known. We propose two optimal methods for building tracks sequentially. The first one uses the labelling of the current multitarget state estimate that minimizes the mean-square labeled optimal subpatternassignment error. This method requires knowledge of the posterior density of the vector-valued state. The second assigns the labeling that maximizes the probability that the current multi-targetstate estimate is optimally linked with the available tracks at the previous time step. In this case, we only require knowledge of the random finite-set posterior density without labels

    Testicular fusocellular rhabdomyosarcoma as a metastasis of elbow sclerosing rhabdomyosarcoma: A clinicopathologic, immunohistochemical and molecular study of one case

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    Sclerosing rhabdomyosarcoma (SRMS) is an infrequent variant of rhabdomyosarcoma characterized by extensive intercellular hyaline fibrosis. We report the case of a 37 year-old male with a 9 Ă— 6 cm SRMS on the right elbow. Histologically, the tumor showed an abundant extracellular hyaline matrix with extratumoral vascular emboli and microscopic foci of fusocellular embryonal rhabdomyosarcoma (FRMS) separated by a fibrotic band from the sclerosing areas. One year later the patient presented with a right intratesticular tumor of 1.2 Ă— 0.8 cm, which was reported as pure FRMS. Immunohistochemically, SRMS was positive only for MyoD1 and Vimentin and negative for Myogenin and Desmin. Both the elbow emboli with the extratumoral foci of FRMS and the intratesticular tumor were positive for Myogenin, MyoD1, Vimentin and Desmin. Using fluorescent in situ hybridization (FISH), the SRMS and the FRMS tumor cells of the elbow and the FRMS tumor cells of the testis were found to be negative for FOXO1A translocation in chromosome 13. PCR chimeric transcriptional products PAX3-FKHR and PAX7-FKHR were not found. Six months following testicular resection, the patient died of multiple metastases in the mediastinum, lung and right thigh

    Initiation codon selection is accomplished by a scanning mechanism without crucial initiation factors in sindbis virus subgenomic mRNA

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    Translation initiation of alphavirus subgenomic mRNA (sgmRNA) can occur in the absence of several initiation factors (eIFs) in infected cells; however, the precise translation mechanism is still poorly understood. In this study, we have examined the mechanism of initiation and AUG selection in Sindbis virus (SINV) sgmRNA. Our present findings suggest that sgmRNA is translated via a scanning mechanism, since the presence of a hairpin structure before the initiation codon hampers protein synthesis directed by this mRNA. In addition, translation is partially recovered when an in-frame AUG codon is placed upstream of this hairpin. This scanning process takes place without the participation of eIF4A and active eIF2. These results, combined with our findings through modifying the SINV sgmRNA leader sequence, do not support the possibility of a direct initiation from the start codon without previous scanning, or a shunting mechanism. Moreover, studies carried out with sgmRNAs containing two alternative AUG codons within a good context for translation reveal differences in AUG selection which are dependent on the cellular context and the phosphorylation state of eIF2α. Thus, initiation at the additional AUG is strictly dependent on active eIF2, whereas the genuine AUG codon can start translation following eIF2α inactivation. Collectively, our results suggest that SINV sgmRNA is translated by a scanning mechanism without the potential participation of crucial eIFs. A model is presented that explains the mechanism of initiation of mRNAs bearing two alternative initiation codonsThis work was supported by a DGICYT (Dirección General de Investigación Científica y Técnica. Ministerio de Economía y Competitividad, Spain) grant BFU2012-31861. M.G.-M. is holder of a FPI (Formación de Personal Investigador) fellowship. The Institutional Grant awarded to the Centro de Biología Molecular “Severo Ochoa” (CSIC-UAM) by the Fundación Ramón Areces is acknowledge

    Bayesian Road Estimation Using Onboard Sensors

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    This paper describes an algorithm for estimating the road ahead of a host vehicle based on the measurements from several onboard sensors: a camera, a radar, wheel speed sensors,and an inertial measurement unit.We propose a novel road model that is able to describe the road ahead with higher accuracy than the usual polynomial model. We also develop a Bayesian fusionsystem that uses the following information from the surroundings: lane marking measurements obtained by the camera and leading vehicle and stationary object measurements obtained bya radar–camera fusion system. The performance of our fusion algorithm is evaluated in several drive tests. As expected, the more information we use, the better the performance is.Index Terms—Camera, information fusion, radar, road geometry,unscented Kalman filter (UKF)

    Analysis of air mass dependence of three photovoltaic arrays

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    The solar spectrum, which is also could be described by air mass factor, has a significant relationship with the performance of photovoltaic modules. The air mass dependence has been investigated by a theoretical method as well as an actual case of three different photovoltaic arrays: polycrystalline silicon, amorphous silicon and cadmium telluride, at the EUIT AgrĂ­cola-UPM (Madrid, Spain, 40.4426oN, 3.7295oW). The calculating results show that: AM dependence of poly-Si array is positive because an elevating AM-value indicates a red shift and poly-Si module is more red sensitive; On the contrary, as a-Si module and CdTe module are more blue sensitive, their AM dependences are negative. Furthermore, the outdoor AM dependences of three arrays are corresponding to the calculating results although the thermal annealing effect could be superimposed on spectral effect in the case of a-Si. Keywords: PV system, spectral response, polycrystalline silicon, a-Si, CdT

    Early degradation of PV modules and guaranty conditions

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    CIEMAT PVLabDER has largely increased its demand on testing and characterizing PV plants, according to the fast growth of PV installed capacity in Spain. One of the topics in which manufacturers, promoters, and owners of the plants are more interested in, is the possible degradation of PV modules and its relationship to guarantee contracts, as it is related to subsidies. This paper presents some findings in campaigns of PV plants evaluation carried out during last years. This evaluation usually consists of visual inspection, I-V curve measurement in the fields (the whole plant or selected areas), thermal evaluation by IR imaging, and, in some cases, measurement of the I-V characteristic and thermal behaviour of selected modules in the plant, chosen by the laboratory. It must be noticed that new defects that grow when the module is into operation may appear in modules initially free of them (named as hidden manufacturing defects). Usually some of these hidden defects that only appear in normal operation are not detected in reliability tests (EN61215 or EN 61646) [4][5] due to the different operational conditions of the module in the standard tests and in the field (serial-parallel connection of many PV modules, power inverter influence, over voltage on wires, etc.

    Early degradation of PV modules and guaranty conditions

    Get PDF
    CIEMAT PVLabDER has largely increased its demand on testing and characterizing PV plants, according to the fast growth of PV installed capacity in Spain. One of the topics in which manufacturers, promoters, and owners of the plants are more interested in, is the possible degradation of PV modules and its relationship to guarantee contracts, as it is related to subsidies. This paper presents some findings in campaigns of PV plants evaluation carried out during last years. This evaluation usually consists of visual inspection, I-V curve measurement in the fields (the whole plant or selected areas), thermal evaluation by IR imaging, and, in some cases, measurement of the I-V characteristic and thermal behaviour of selected modules in the plant, chosen by the laboratory. It must be noticed that new defects that grow when the module is into operation may appear in modules initially free of them (named as hidden manufacturing defects). Usually some of these hidden defects that only appear in normal operation are not detected in reliability tests (EN61215 or EN 61646) [4][5] due to the different operational conditions of the module in the standard tests and in the field (serial-parallel connection of many PV modules, power inverter influence, over voltage on wires, etc.

    Influence of initial power stabilization over crystalline-Si photovoltaic modules maximum power

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    Measurements that suppliers offer in specification sheets are not always close to the actual power measured in independent laboratories such as CIEMAT. Independent measurements tend to be lower than those printed on the label sometimes even lower than the allowed tolerance indicated by the manufacturer on the same label. Furthermore, a potentially significant power reduction has been reported when Standard EN50380 (which requires photovoltaic (PV) modules to be exposed to more than 20 kWh/m2 of sunlight prior to taking the measurements that appear on the label) is followed. This is the initial power stabilization and this work studies the power stabilization that tends to appear in crystalline PV modules. Crystalline PV modules usually decrease in power around 1%, but decreases >4% have also been reported. These power losses are only detected after the mentioned power stabilizatio
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