Stati limite ultimi per spalle da ponte

Nonostante la risposta dinamica delle spalle possa influenzare la prestazione di un ponte, la valutazione di questo effetto è complicata per l’elevatissima domanda computazionale dei modelli numerici completi, che includano esplicitamente nel modello strutturale la spalla e il terreno che interagisce con essa. In questa nota si fornisce un contributo alla definizione di un approccio semplificato di analisi basato sulla simulazione del comportamento delle spalle tramite macro-elementi, focalizzando in particolare l’attenzione sulle condizioni ultime dell’insieme spalla-terreno. Tramite l’applicazione dei teoremi di estremo dell’analisi limite, attraverso il metodo degli elementi finiti con mesh adattiva, si individuano i potenziali meccanismi plastici del sistema spalla-terreno, considerando anche meccanismi combinati in cui i pali di fondazione della spalla possano raggiungere la propria resistenza insieme al terreno. Si propone quindi un modello per la previsione della resistenza ultima delle spalle in condizioni di carico multi-assiali, identificato tramite la calibrazione di un numero limitato di parametri costitutivi. È mostrato come gli effetti inerziali associati all’azione sismica possano essere incorporati nel modello tramite una contrazione e rotazione della superficie che rappresenta le condizioni ultime della spalla, definita nello spazio delle forze. La superficie così definita si presta a essere inclusa in una rappresentazione generale della risposta sismica di una spalla attraverso la definizione di un macro-elemento per le spalle, ma è anche utilizzabile più immediatamente come uno strumento di verifica della resistenza delle spalle in un approccio alla progettazione sismica in termini di forze statiche equivalenti

Control of Ground Movements for a Multi-Level-Anchored, Diaphragm Wall During Excavation

An excavation up to 23m deep for the Dana Farber research tower in the Longwood medical area of Boston, was supported by a permanent perimeter diaphragm wall extending into the underlying conglomerate and up to 6 levels of prestressed tiebacks anchored in the rock. The lateral earth support system was very successful in limiting wall deflections to less than ±15mm on each of the four sides of the excavation. However, ground surface settlements up to 65mm occurred on two sides and were attributed to ground losses that occurred when tiebacks were installed through overpressured sand layers at depths of 15-18m. Finite element simulations are able to describe consistently the effects of the different excavation and support sequences on each side of the project using backfigured soil properties, while surface settlements can be explained by including local ground losses within the analyses

A multiaxial inertial macroelement for bridge abutments

This paper proposes a multiaxial macroelement for bridge abutments that can be included in the global structuralmodel of a bridge to carry out nonlinear dynamic analyses with very much smaller computational effort than can be achieved using continuum representations of embankment and foundation soil behaviour. The proposed macroelement derives a constitutive force–displacement relationship within a rigorous thermodynamic framework and includes important features of non-linearity and directional coupling in characterizing the interactions of the abutment with the soil. In a dynamic analysis, the frequency-dependent response of the system is simulated through the combination of the macroelement with appropriate participating masses. The calibration procedure of the macroelement is based on the assessment of its ultimate capacity and of its response at small displacements, and it is shown that these ingredients can be derived through standardised procedures. In the paper, the macroelement response is validated against the results of fully coupled continuum numerical analyses for a reference soil–abutment system, under both static and seismic loading conditions. We show that the two models achieve similar predictions of maximum and permanent abutment deformations (less than 10–14% difference, respectively) for a suite of three-axis seismic loading events

Bearing Capacity of Spatially Random Cohesive Soil Using Numerical Limit Analyses

This paper describes a probabilistic study of the two dimensional bearing capacity of a vertically loaded strip footing on spatially random, cohesive soil using Numerical Limit Analyses (NLA‐CD). The analyses uses a Cholesky Decomposition (CD) technique with mid‐point discretization to represent the spatial variation in undrained shear strength within finite element meshes for both upper and lower bound analyses, and assumes an isotropic correlation length. Monte Carlo simulations are then used to interpret the bearing capacity for selected ranges of the coefficient of variation in undrained shear strength and the ratio of correlation length to footing width. The results are compared directly with data from a very similar study by Griffiths et al. in which bearing capacity realizations were computed using a method of Local Average Subdivision (LAS) in a conventional displacement‐based Finite Element Method (FEM‐LAS). These comparisons show the same qualitative features, but suggest that the published FEM calculations tend to overestimate the probability of failure at large correlation lengths. The NLA method offers a more convenient and computationally efficient approach for evaluating effects of variability in soil strength properties in geotechnical stability calculations

Ground Heave Due to Jet Grouting Near an Existing Structure

Renovations of the MBTA Copley Station in Boston included construction of a new elevator shaft to improve disabled access to the existing Green Line station. The site is immediately adjacent to the Eastern façade of the historic Old South Church. The construction work required excavation support including a perimeter secant pile wall and a jet-grouted base plug. Significant ground and structural movements were observed during jet grouting, mainly associated with soil displacements during grout injection. A three dimensional numerical model was developed, using the Plaxis 3D Foundation™ program, in order to test the hypothesis that the observed movements of the structure could be associated with the installation of the jet grout piles. The amount of volume expansion associated with installation of jet grout piles is estimated based by calibrating the model to measured ground movements. The finite element model results give a consistent explanation for the observed pattern of movements, including the heave of the church wall and lateral displacements at inclinometers located within the vicinity of the structure, measured at the time when damage occurred. The model assumes there is a vertical line of weakness in the masonry, representative of a pre-existing structural crack, as observed by structural investigations; and hence, confirms the underlying mechanical hypothesis for the source of ground movements

Microbial abundance and community composition in biofilms on in-pipe sensors in a drinking water distribution system

Collecting biofilm samples from drinking water distribution systems (DWDSs) is challenging due to limited access to the pipes during regular operations. We report here the analysis of microbial communities in biofilm and water samples collected from sensors installed in a DWDS where monochloramine is used as a residual disinfectant. A total of 52 biofilm samples and 14 bulk water samples were collected from 17 pipe sections representing different water ages. Prokaryotic genome copies (bacterial and archaeal 16S rRNA genes, Mycobacterium spp., ammonia-oxidizing bacteria (AOB), and cyanobacteria) were quantified with droplet digital PCR, which revealed the abundance of these genes in both biofilm and water samples. Prokaryotic 16S rRNA gene sequencing analysis was carried out for a subset of the samples (12 samples from four sites). Mycobacterium and AOB species were dominant in the DWDS sections with low water age and sufficient residual monochloramine, whereas Nitrospira species (nitrite-oxidizing bacteria) dominated in the sections with higher water age and depleted monochloramine level, suggesting the occurrence of nitrification in the studied DWDS. The present study provides novel information on the abundance and identity of prokaryotes in biofilms and water in a full-scale operational DWDS.Collecting biofilm samples from drinking water distribution systems (DWDSs) is challenging due to limited access to the pipes during regular operations. We report here the analysis of microbial communities in biofilm and water samples collected from sensors installed in a DWDS where monochloramine is used as a residual disinfectant. A total of 52 biofilm samples and 14 bulk water samples were collected from 17 pipe sections representing different water ages. Prokaryotic genome copies (bacterial and archaeal 16S rRNA genes, Mycobacterium spp., ammonia-oxidizing bacteria (AOB), and cyanobacteria) were quantified with droplet digital PCR, which revealed the abundance of these genes in both biofilm and water samples. Prokaryotic 16S rRNA gene sequencing analysis was carried out for a subset of the samples (12 samples from four sites). Mycobacterium and AOB species were dominant in the DWDS sections with low water age and sufficient residual monochloramine, whereas Nitrospira species (nitrite-oxidizing bacteria) dominated in the sections with higher water age and depleted monochloramine level, suggesting the occurrence of nitrification in the studied DWDS. The present study provides novel information on the abundance and identity of prokaryotes in biofilms and water in a full-scale operational DWDSFil: Kitajima, Masaaki. Hokkaido University; Japón. Singapore-MIT Alliance for Research and Technology; SingapurFil: Cruz, Mercedes Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Investigaciones para la Industria Química. Universidad Nacional de Salta. Facultad de Ingeniería. Instituto de Investigaciones para la Industria Química; Argentina. Nanyang Technological University; SingapurFil: Williams, Rohan Benjamin Hugh. National University of Singapore; SingapurFil: Wuertz, Stefan. National University of Singapore; Singapur. Nanyang Technological University; SingapurFil: Whittle, Andrew J.. Singapore-MIT Alliance for Research and Technology; Singapur. Massachusetts Institute of Technology; Estados Unido

\u3cem\u3eHubble Space Telescope\u3c/em\u3e/Faint Object Spectrograph Spectroscopy of Spatially Resolved Narrow-Line Regions in the Seyfert 2 Galaxies NGC 2110 and NGC 5929

We present the results of UV and optical Hubble Space Telescope/Faint Object Spectrograph spectroscopy of bright, extranuclear regions of line emission in the Seyfert galaxies NGC 2110 and NGC 5929. We have obtained spectra of the brightest region of the ``nuclear jet\u27\u27 of NGC 2110 (75 pc from the nucleus) and of the southwest emission-line cloud of NGC 5929 (90 pc from the nucleus), in the G130H (1090-1605 Å), G190H (1570-2310 Å), G400H (3235-4780 Å), and G570H (4570-6820 Å) configurations. The observed line ratios are compared with the predictions of the two component (matter- and ionization-bounded, MB-IB), central source photoionization models of Binette, Wilson, {\amp} Storchi-Bergmann and of the fast, photoionizing (``autoionizing\u27\u27) shock models of Dopita {\amp} Sutherland. In both objects, the significant reddening inferred from the Balmer line ratios and/or its uncertainty limit the utility of the ultraviolet carbon lines C IV λ1549 and C III] λ1909 for discrimination between the central source and shock-induced photoionization mechanisms. In NGC 2110, shock+precursor models with a shock velocity of ~=400 km s-1 provide a better match to the data than the MB-IB models. However, given the simplifying assumptions made in the latter models, photoionization by a central source cannot be ruled out. We investigate whether photoionizing shocks in the emission-line region of NGC 2110 can power the extended, soft X-ray emission north of the nucleus and find that shock velocities higher than 500 km s-1 are required. In NGC 5929, the MB-IB models have problems reproducing the strengths of the neon lines, while shock+precursor models with a velocity ~=300 km s-1 provide a good match to the data. For both galaxies, the emission-line powers and volumes of the ionized gas inferred from observations imply that both the preshock density (n0) and magnetic parameter (B0/n1/20) must be relatively high (n0\u3e10 cm-3 B0/n1/20~=4 μG cm3/2) for the photoionizing shock models to be viable. Based on observations with the NASA/ESA Hubble Space Telescope obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555

Prediction and interpretation of the performance of a deep excavation in Berlin sand

This paper describes the application of a generalized effective stress soil model, MIT‐S1, within a commercial finite element program, for simulating the performance of the support system for the 20m deep excavation of the M1 pit adjacent to the main station “Hauptbahnhof” in Berlin. The M1 pit was excavated underwater and supported by a perimeter diaphragm wall with a single row of prestressed anchors. Parameters for the soil model were based on an extensive program of laboratory tests on the local Berlin Sands. This calibration process highlights the practical difficulties in both measurements of critical state soil properties and in model parameter selection. The predictions of excavation performance are strongly affected by vertical profiles of two key state parameters, the initial earth pressure ratio, K0, and the in‐situ void ratio, e0. These are estimated from field dynamic penetration test data and geological history. The results show good agreement between computed and measured wall deflections and tie‐back forces for three instrumented sections. Much larger wall deflections were measured at a fourth section and may be due to spatial variability in sand properties that has not been considered in the current analyses. The results of this study highlight the importance of basic state parameter information for successful application of advanced soil models.National Science Foundation (U.S.) (Wester Europe program grant INT-0089508)German Academic Exchange Service (DAAD

Mesoscale properties of clay aggregates from potential of mean force representation of interactions between nanoplatelets

Face-to-face and edge-to-edge free energy interactions of Wyoming Na-montmorillonite platelets were studied by calculating potential of mean force along their center to center reaction coordinate using explicit solvent (i.e., water) molecular dynamics and free energy perturbation methods. Using a series of configurations, the Gay-Berne potential was parametrized and used to examine the meso-scale aggregation and properties of platelets that are initially random oriented under isothermal-isobaric conditions. Aggregates of clay were defined by geometrical analysis of face-to-face proximity of platelets with size distribution described by a log-normal function. The isotropy of the microstructure was assessed by computing a scalar order parameter. The number of platelets per aggregate and anisotropy of the microstructure both increases with platelet plan area. The system becomes more ordered and aggregate size increases with increasing pressure until maximum ordered state at confining pressure of 50 atm. Further increase of pressure slides platelets relative to each other leading to smaller aggregate size. The results show aggregate size of (3–8) platelets for sodium-smectite in agreement with experiments (3–10). The geometrical arrangement of aggregates affects mechanical properties of the system. The elastic properties of the meso-scale aggregate assembly are reported and compared with nanoindentation experiments. It is found that the elastic properties at this scale are close to the cubic systems. The elastic stiffness and anisotropy of the assembly increases with the size of the platelets and the level of external pressure.National Science Foundation (U.S.) (Extreme Science and Engineering Discovery Environment (XSEDE) and Texas Advanced Computing Center Grant TG-DMR100028)X-Shale Hub at MITSingapore-MIT Alliance for Research and Technolog

Neuroblastoma patient outcomes, tumor differentiation, and ERK activation are correlated with expression levels of the ubiquitin ligase UBE4B.

BackgroundUBE4B is an E3/E4 ubiquitin ligase whose gene is located in chromosome 1p36.22. We analyzed the associations of UBE4B gene and protein expression with neuroblastoma patient outcomes and with tumor prognostic features and histology.MethodsWe evaluated the association of UBE4B gene expression with neuroblastoma patient outcomes using the R2 Platform. We screened neuroblastoma tumor samples for UBE4B protein expression using immunohistochemistry. FISH for UBE4B and 1p36 deletion was performed on tumor samples. We then evaluated UBE4B expression for associations with prognostic factors and with levels of phosphorylated ERK in neuroblastoma tumors and cell lines.ResultsLow UBE4B gene expression is associated with poor outcomes in patients with neuroblastoma and with worse outcomes in all patient subgroups. UBE4B protein expression was associated with neuroblastoma tumor differentiation, and decreased UBE4B protein levels were associated with high-risk features. UBE4B protein levels were also associated with levels of phosphorylated ERK.ConclusionsWe have demonstrated associations between UBE4B gene expression and neuroblastoma patient outcomes and prognostic features. Reduced UBE4B protein expression in neuroblastoma tumors was associated with high-risk features, a lack of differentiation, and with ERK activation. These results suggest UBE4B may contribute to the poor prognosis of neuroblastoma tumors with 1p36 deletions and that UBE4B expression may mediate neuroblastoma differentiation