1,228 research outputs found

    Microdeformation in Vredefort rocks; evidence for shock metamorphism

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    Planar microdeformations in quartz from basement or collar rocks of the Vredefort Dome have been cited for years as the main microtextural evidence for shock metamorphism in this structure. In addition, Schreyer describes feldspar recrystallization in rocks from the center of the Dome as the result of transformation of diaplectic glass, and Lilly reported the sighting of mosaicism in quartz. These textural observations are widely believed to indicate either an impact or an internally produced shock origin for the Vredefort Dome. Two types of (mostly sub) planar microdeformations are displayed in quartz grains from Vredefort rocks: (1) fluid inclusion trails, and (2) straight optical discontinuities that sometimes resemble lamellae. Both types occur as single features or as single or multiple sets in quartz grains. Besides qualitative descriptions of cleavage and recrystallization in feldspar and kinkbands in mica, no further microtextural evidence for shock metamorphism at Vredefort has been reported to date. Some 150 thin sections of Vredefort basement rocks were re-examined for potential shock and other deformation effects in all rock-forming minerals. This included petrographic study of two drill cores from the immediate vicinity of the center of the Dome. Observations recorded throughout the granitic core are given along with conclusions

    Oligodendroglioma cells lack glutamine synthetase and are auxotrophic for glutamine, but do not depend on glutamine anaplerosis for growth

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    In cells derived from several types of cancer, a transcriptional program drives high consumption of glutamine (Gln), which is used for anaplerosis, leading to a metabolic addiction for the amino acid. Low or absent expression of Glutamine Synthetase (GS), the only enzyme that catalyzes de novo Gln synthesis, has been considered a marker of Gln-addicted cancers. In this study, two human cell lines derived from brain tumors with oligodendroglioma features, HOG and Hs683, have been shown to be GS-negative. Viability of both lines depends from extracellular Gln with EC of 0.175 ± 0.056 mM (Hs683) and 0.086 ± 0.043 mM (HOG), thus suggesting that small amounts of extracellular Gln are sufficient for OD cell growth. Gln starvation does not significantly affect the cell content of anaplerotic substrates, which, consistently, are not able to rescue cell growth, but causes hindrance of the Wnt/β-catenin pathway and protein synthesis attenuation, which is mitigated by transient GS expression. Gln transport inhibitors cause partial depletion of intracellular Gln and cell growth inhibition, but do not lower cell viability. Therefore, GS-negative human oligodendroglioma cells are Gln-auxotrophic but do not use the amino acid for anaplerosis and, hence, are not Gln addicted, exhibiting only limited Gln requirements for survival and growth

    A comprehensive study of noble gases and nitrogen in Hypatia, a diamond-rich pebble from SW Egypt

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    This is a follow-up study of a work by Kramers et al. (2013) on an unusual diamond-rich rock found in the SW side of the Libyan Desert Glass strewn field. This pebble, called Hypatia, is composed of almost pure carbon. Transmission Electron Microscopy and X-ray diffraction results reveal that Hypatia is made of defect-rich diamond containing lonsdaleite and deformation bands. These characteristics are compatible with an impact origin on Earth and/or in space. We analyzed concentrations and isotopic compositions of all five noble gases and nitrogen in several mg sized Hypatia samples. These data confirm that Hypatia is extra-terrestrial. The sample is rich in trapped noble gases with an isotopic composition close to the meteoritic Q component. 40Ar/36Ar ratios in individual steps are as low as 0.4. Concentrations of cosmic-ray produced 21Ne correspond to a nominal cosmic-ray exposure age of ca. 0.1 Myr if produced in a typical m-sized meteoroid. Such an atypically low nominal exposure age suggests high shielding in a considerably larger body. In addition to the Xe-Q composition, an excess of radiogenic 129Xe (from the decay of extinct 129I) is observed (129Xe/132Xe = 1.18 +/- 0.03). Two N components are present, an isotopically heavy component ({\delta}15N = +20 permil) released at low temp. and a major light component ({\delta}15N = -110 permil) at higher temp. This disequilibrium in N suggests that the diamonds in Hypatia were formed in space. Our data are broadly consistent with concentrations and isotopic compositions of noble gases in at least three different types of carbon-rich meteoritic materials. However, Hypatia does not seem to be related to any of these materials, but may have sampled a similar cosmochemical reservoir. Our study does not confirm the presence of exotic noble gases that led Kramers et al. to propose that Hypatia is a remnant of a comet that impacted the Earth

    Integrating a Global Induction Mechanism into a Sequent Calculus

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    Most interesting proofs in mathematics contain an inductive argument which requires an extension of the LK-calculus to formalize. The most commonly used calculi for induction contain a separate rule or axiom which reduces the valid proof theoretic properties of the calculus. To the best of our knowledge, there are no such calculi which allow cut-elimination to a normal form with the subformula property, i.e. every formula occurring in the proof is a subformula of the end sequent. Proof schemata are a variant of LK-proofs able to simulate induction by linking proofs together. There exists a schematic normal form which has comparable proof theoretic behaviour to normal forms with the subformula property. However, a calculus for the construction of proof schemata does not exist. In this paper, we introduce a calculus for proof schemata and prove soundness and completeness with respect to a fragment of the inductive arguments formalizable in Peano arithmetic.Comment: 16 page

    Spatiotemporal Coherent Control of Light through a Multiple Scattering Medium with the Multispectral Transmission Matrix

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    We report the broadband characterization of the propagation of light through a multiple scattering medium by means of its multispectral transmission matrix. Using a single spatial light modulator, our approach enables the full control of both the spatial and spectral properties of an ultrashort pulse transmitted through the medium. We demonstrate spatiotemporal focusing of the pulse at any arbitrary position and time with any desired spectral shape. Our approach opens new perspectives for fundamental studies of light-matter interaction in disordered media, and has potential applications in sensing, coherent control, and imaging

    Acrylamide levels in cooked rice, tomato sauces and some fast food on the Italian market

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    This study reports the results of evaluation of acrylamide levels in some foods that are common on the Italian market. Three foods commonly found in the national diet (rice, tomato sauce and fast food), were examined with the gas chromatograph (GC)/mass spectrometer (MS) analytical method. Results show that rice differs from risotto with respect to acrylamide levels: values of less than 50 \u3bcg/kg, for boiled rice, increase to 113 \u3bcg/kg when various ingredients are added to produce risotto. Similar results were found for tomato sauce on the Italian market: acrylamide values were less than 50 \u3bcg/kg for simple tomato sauce, to 124 \u3bcg/kg when other ingredients such as olives and capers were added. Fast foods (e.g., fried potatoes) contained the highest observed acrylamide levels, probably from cooking methods and acrylamide-rich precursors. For two fried potatoes of the same type, very differentiated values resulted (136 and 294 \u3bcg/kg)

    Measurement of the plasma astrophysical S factor for the 3He(D, p)4He reaction in exploding molecular clusters

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    The plasma astrophysical S factor for the 3He(D, p)4He fusion reaction was measured for the first time at temperatures of few keV, using the interaction of intense ultrafast laser pulses with molecular deuterium clusters mixed with 3He atoms. Different proportions of D2 and 3He or CD4 and 3He were mixed in the gas jet target in order to allow the measurement of the cross-section for the 3He(D, p)4He reaction. The yield of 14.7 MeV protons from the 3He(D, p)4He reaction was measured in order to extract the astrophysical S factor at low energies. Our result is in agreement with other S factor parameterizations found in the literature

    Focusing in Asynchronous Games

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    Game semantics provides an interactive point of view on proofs, which enables one to describe precisely their dynamical behavior during cut elimination, by considering formulas as games on which proofs induce strategies. We are specifically interested here in relating two such semantics of linear logic, of very different flavor, which both take in account concurrent features of the proofs: asynchronous games and concurrent games. Interestingly, we show that associating a concurrent strategy to an asynchronous strategy can be seen as a semantical counterpart of the focusing property of linear logic
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