Modellizzare lo sviluppo territoriale “dal basso” entro il quadro della ricerca educativa sostenibile: Un contributo a più voci riguardo ai processi trasformativi, innovativi e partecipativi che rispondono a esigenze socioculturali di tipo locale e ai bisogni speciali

This paper joins together different educational research approaches, which highlight the relevance of educational research as a stimulus to bottom-up transformative processes, and as a tool to make them valuable at the local (territorial) and global (national, European) level. Each approach is dedicated to a single region or administrative district of Italy, within which their cases unfold (namely: Apulia, Lombardy, and Trento). Moreover, as made apparent by the joint diagram, they all share assumptions with regards to the ontology of the macrolevel, which constitute the bases for their comparability. The final section subsumes individual results by projecting them against a theo-retical background that stresses on the role of bottom-up processes as fos-terers of transformative resilience; the latter allows for adaptation without depletion of contextual elements, nor the avoidance of selective pressures. As such, educational research qualifies as one of the cornerstones of sus-tainable development.Questo articolo unisce differenti approcci per la ricerca educativa che sot-tolineano la rilevanza della stessa come stimolo per i processi trasformativi bottom-up e, parimenti, come strumento per valorizzarli a livello locale (territorio) e globale (nazione, UE). Ciascun approccio è dedicato a una singola regione o suddivisione amministrativa italiana, entro cui hanno luogo i casi studiati (Lombardia, Puglia, Trento). Inoltre, come si può evincere dallo schema collettivo, condividono tutti e tre degli assunti di base sulla suddivisione ontologica del macrolivello di analisi: tale elemento condiviso costituisce il fondamento della loro comparabilità. La sezione finale riassume i risultati individuali ponendoli nel contesto teorico dell'importanza dei processi bottom-up come chiavi della resilienza trasformativa; quest'ultima, infatti, risulta da un processo di adattamento che non esaurisce gli elementi contestuali né evita di misurarsi con le pressioni selettive. In quanto tale, la ricerca educativa si qualifica come uno dei capisaldi dello sviluppo sostenibile.  

acne ra 1 2 a novel uv selective face cream for patients with acne efficacy and tolerability results of a randomized placebo controlled clinical study

SummaryBackground General skincare measures such as the use of moisturisers and products containing adequate photoprotection are important components of acne patients' management to complement the pharmacological regimen. Acne RA-1,2 is a novel dermato-cosmetic product which contains selective photofilters and active ingredients against the multifactorial pathophysiology of acne. Objectives To evaluate the tolerability of Acne RA-1,2 and its effect on the clinical signs of acne. Methods This double-blind, placebo-controlled study randomized 40 adult patients with 10-25 comedones per half face to once-daily application of Acne RA-1,2 or placebo for 8 weeks. Evaluations after 4 and 8 weeks included the number of comedones, transepidermal water loss (TEWL), sebum production, and tolerability. Results In the Acne RA-1,2 group, there was a significant 35% decrease in the mean number of comedones from 26 at baseline to 17 at Week 8 (P<.001), a 7% significant reduction in TEWL (9.32 to 8.66 g/h/m2; P<.001), and a 24% significant reduction in sebum production (154.8 to 117.6 μg/cm2; P<.001). The reductions in TEWL and sebum production were significantly greater than those in the placebo group at Weeks 4 and 8 (P<0.05). There were no adverse events. Conclusions Acne RA-1,2 was well tolerated and effective at reducing comedones and sebum production and improving epidermal barrier function. These results suggest that Acne RA-1,2 is useful against acne-prone facial skin, particularly as it targets sebum production, which topical pharmacological acne therapies do not address

Non-wage benefits, corporate ownership and firm performance in post-communist economies: evidence from Ukraine

International audienceThe economic reforms in the transition economies of Central and Eastern Europe have fundamentally reshaped ownership and governance of economic production, notably through the privatization of former state-owned enterprises. These reforms were expected to transform management practices by displacing ‘cradle-to-grave’ welfare arrangements administered by state-owned enterprises. Using data drawn from two large samples of Ukrainian establishments, we investigate, in two different time points, the relationship between non-wage benefits and firm performance during the period of transition to a market economy (1994–2004). We found that non-wage benefits continued to be a critical feature of HRM practices in Ukraine during this period, and were positively associated with firm performance

Dye Solar Cells: Basic and Photon Management Strategies

Since the introduction and development of the dye-sensitized solar cell (DSC) several efforts have been made to optimize the materials involved in the photo-electrochemical process and to improve the light conversion efficiency of the device , by exploiting a low cost production process based on simple fabrication methods, similar to those used in printing processes

PRODUÇÃO DE VERMICOMPOSTO A PARTIR DA CRIAÇÃO DE MINHOCAS Eisenia foetida COMO ALTERNATIVA DE PRODUÇÃO PARA AGRICULTURA FAMILIAR

ABSTRACT: The use of vermicompost is one of the alternatives that can assist in the minimization of chemical inputs in crop production and stimulate the agroecological transition in family farming. This study aims since 2007, developing and disseminating low-cost technologies for waste recycling plant by raising earthworms (Eisenia foetida) which can be used in agroforestry systems (AFS) of the farmers in Marabá and region. The activities developed in the course of Agronomy, Federal University of Pará (UFPA) - University Campus in Marabá and in the research projects and development fostered further research and extension of this work, they being: the implementation and monitoring of earthworm experiment on the campus of UFPA, another at the Federation of Family Farming Cooperatives of southern Pará (FECAT), and in the Settlements of the region, as well as distribution headquarters for the formation of earthworm in the settlements and distribution of vermicompost. The results of this project that articulated the activities of teaching and research-extension involving teachers, students and technicians with family farmers, can be highlighted: field days and lectures for the diffusion of technology, distribution of arrays of worms and deployment of five earthworm with high production of earthworms and vermicompost.   KEYWORDS: earthworm, family farming, organic inputs.RESUMO: A utilização de vermicomposto é uma das alternativas que podem auxiliar na minimização por insumos químicos na produção vegetal e estimular a transição agroecológica na agricultura familiar. Este trabalho tem como objetivos desde 2007, desenvolver e difundir tecnologias de baixo custo para a reciclagem de resíduos vegetais através da criação de minhocas (Eisenia foetida) que possam ser utilizados nos sistemas agroflorestais (SAF) dos agricultores familiares de Marabá e região. As atividades desenvolvidas no curso de Agronomia da Universidade Federal do Pará (UFPA) - Campus Universitário de Marabá e nos projetos de pesquisa e desenvolvimento fomentaram as ações de pesquisa e extensão deste trabalho, sendo elas: a implantação e acompanhamento de minhocário experimental no campus da UFPA, outro na Federação das Cooperativas da Agricultura Familiar do Sul do Pará (FECAT), e em Assentamentos da região, bem como distribuição de matrizes para a formação de minhocários nos assentamentos e distribuição do vermicomposto. Como resultados desse projeto que articulou as atividades ensino-pesquisa-extensão envolvendo docentes, discentes e técnicos junto a agricultores familiares, podem-se destacar: dias de campo e palestras para a difusão da tecnologia, distribuição de matrizes de minhocas e a implantação de cinco minhocários com alta produção de minhocas e vermicomposto. PALAVRAS-CHAVE: agricultura familiar, minhocário, insumos biológicos

Low-temperature stability and sensing performance of mid-infrared bloch surface waves on a one-dimensional photonic crystal

The growing need for new and reliable surface sensing methods is arousing interest in the electromagnetic excitations of ultrathin films, i.e., to generate electromagnetic field distributions that resonantly interact with the most significant quasi-particles of condensed matter. In such a context, Bloch surface waves turned out to be a valid alternative to surface plasmon polaritons to implement high-sensitivity sensors in the visible spectral range. Only in the last few years, however, has their use been extended to infrared wavelengths, which represent a powerful tool for detecting and recognizing molecular species and crystalline structures. In this work, we demonstrate, by means of high-resolution reflectivity measurements, that a one-dimensional photonic crystal can sustain Bloch surface waves in the infrared spectral range from room temperature down to 10 K. To the best of our knowledge, this is the first demonstration of infrared Bloch surface waves at cryogenic temperatures. Furthermore, by exploiting the enhancement of the surface state and the high brilliance of infrared synchrotron radiation, we demonstrate that the proposed BSW-based sensor has a sensitivity on the order of 2.9 cm–1 for each nanometer-thick ice layer grown on its surface below 150 K. In conclusion, we believe that Bloch surface wave-based sensors are a valid new class of surface mode-based sensors for applications in materials science

Body mass index in HER2-negative metastatic breast cancer treated with first-line paclitaxel and bevacizumab

The evidence emerged from the TOURANDOT trial encourages evaluating the role of anthropometric determinants on treatment outcomes in HER2-negative metastatic breast cancer patients treated with bevacizumab-including regimens. We thus analyzed data from a subgroup of these patients from a larger cohort previously assessed for treatment outcomes. Patients were included in the present analysis if body mass index values had been recorded at baseline. Clinical benefit rates, progression free survival and overall survival were assessed for the overall study population and subgroups defined upon molecular subtype. One hundred ninety six patients were included (N:196). Body mass index showed no impact on clinical benefit rates in the overall study sample and in the luminal cancer subset (p = 0.12 and p = 0.79, respectively), but did so in the triple negative subgroup, with higher rates in patients with body mass index ≥25 (p = 0.03). In the overall study sample, body mass index did no impact progression free or overall survival (p = 0.33 and p = 0.67, respectively). Conversely, in triple negative patients, progression free survival was significantly longer with body mass index ≥25 (6 vs 14 months, p = 0.04). In this subset, overall survival was more favorable (25 vs 19 months, p = 0.02). The impact of the molecular subtype was confirmed in multivariate models including the length of progression free survival, and number of metastatic sites (p &lt; 0.0001). Further studies are warranted to confirm our findings in more adequately sized, ad hoc, prospective studies

DISTRIBUIÇÃO DE FUNGOS MICORRÍZICOS NOS ASSENTAMENTOS PALMARES E ARARAS

RESUMEN: Hongos micorrizógenos arbusculares (HMA) pueden ser importantes para la nutrición de las plantas, especialmente en suelos de baja fertilidad y alta acidez, como es el caso de los suelos amazónicos. En este contexto, este estudio tuvo como objetivo difundir el uso de hongos formadores de micorrizas para la producción de plántulas de árboles forestales para su uso en sistemas agroforestales en los asentamientos de Pará sureste La obra se llevó a cabo entre marzo y diciembre 2009, a través de una cultura de la trampa con Brachiaria brizantha para la multiplicación de hongos y la producción del inoculo que se distribuirán de la demanda identificada en los proyectos de asentamiento en las zonas rurales (AP) en el suroeste de Pará. Se cumplieron los catorce (14) familias de P. A. Palmares y siete (7) en P. A. Araras, donde distribuyeron un total de tres mil y ochenta dosis (3080) de las diferentes culturas. Así se hizo evidente que hay interés en los agricultores a mejorar sus sistemas de cultivo a través de esta innovadora tecnología que podría ayudar a la sostenibilidad de los sistemas de producción familiar.   PALAVRAS CLAVES: Suministros biológicos, agricultura familiar, sistema de cultivo.RESUMO: Os fungos micorrízicos arbusculares (FMAs) podem ser importantes para a nutrição das plantas, sobretudo em solos de baixa fertilidade e alta acidez, como é o caso dos solos da Amazônia. Diante deste contexto, este trabalho teve como objetivo à difusão da utilização de fungos micorrízicos arbusculares para a produção de mudas de essências florestais para serem empregados em sistemas agroflorestais nos assentamentos da região sudeste do Pará. O trabalho foi conduzido no período entre Março e Dezembro de 2009, através de cultivo armadilha com Brachiaria brizantha para multiplicação dos fungos e produção do inoculante a ser distribuído a partir da demanda identificada em projetos de assentamentos rurais (PAs) na região do sudeste paraense. Foram atendidas quatorze (14) famílias do P. A. Palmares e sete (7) no P. A. Araras, onde foram distribuídas um total de três mil e oitenta (3080) doses de inoculante para diversas culturas. Assim, foi verificado que existe interesse dos agricultores em melhorarem seus sistemas de cultivos através dessa tecnologia inovadora que pode corroborar para sustentabilidade dos sistemas de produção familiares. PALAVRAS-CHAVE: Insumos biológicos, agricultura familiar, sistema de cultivo

Demographic, tumor and clinical features of clinical trials versus clinical practice patients with HER2-positive early breast cancer: results of a prospective study

Several randomized clinical trials (RCTs) have demonstrated the efficacy of trastuzumab-based adjuvant therapy in HER2-positive breast cancer (BC). However, RCT patients may not invariably be representative of patients routinely seen in clinical practice (CP). To address this issue, we compared the clinical and tumor features of RCT and CP patients with HER2-positive BC