A Knowledge Engineering Environment for P&S with Timelines

This paper presents some of the features of a knowledge engineering environment, called KEE N, created to support a timeline based planning based on the A PSI-T RF modeling assumptions. A key feature of the environment is the integration of typical tools for knowledge based modeling and refining with services for validation and verification specialized to planning with timelines

A TGA-based Method for Safety Critical Plan Execution

Safety critical planning and execution is a crucial issue in autonomous systems. This paper proposes a methodology for controller synthesis suitable for timeline-based planning and demonstrates its effectiveness in a space domain where robustness of execution is a crucial property. The proposed approach uses Timed Game Automata (TGA) for formal modeling and the UPPAAL-TIGA model checker for controllers synthesis. An experimental evaluation is performed using a real-world control system

Enriching APSI with Validation Capabilities: the KEEN environment and its use in Robotics

This paper presents the KnowledgE ENgineering (KEEN) design support system in which Validation and Verification (V&V) methods are used to strengthen onground development of software for plan-based autonomy. In particular, the paper describes a collection of verification methods, based on Timed Game Automata (TGA), deployed for the design and development of timeline-based Planning and Scheduling (P&S) applications within the APSI-TRF framework. The KEENs V&V functionalities are illustrated describing software development to synthesize plans for a planetary rover

USING VALIDATION AND VERIFICATION TECHNIQUES FOR ROBUST PLAN EXECUTION

This paper describes the exploitation of a Validation and Verification technique aiming at enriching the support capabilities of the KnowledgE ENgineering (KEEN) software environment. In particular, the work reports on the formal synthesis of a plan controller associated to a flexible temporal plan. The controller synthesis exploits Timed Game Automata (TGA) for formal modeling and UPPAAL-TIGA as a model checker. The paper introduces a detailed experimental analysis on a real-world case study demonstrating the viability of the approach. In particular, it is shown how the controller synthesis overhead is compatible with the performance expected from a short horizon planner

Riduzione delle emissioni di ammoniaca nell’agricoltura mediterranea attraverso tecniche innovative di fertirrigazione con liquami (LIFE16 ENV/ES/000400)

Esta publicación ha sido elaborada como resultado de los trabajos realizados dentro del proyecto LIFE ARIMEDA: Reducción de emisiones de amoníaco en la agricultura mediterránea a través de técnicas innovadoras de fertirrigación con purín (LIFE16 ENV/ES/000400). El proyecto LIFE ARIMEDA ha recibido fondos del Programa LIFE de la Unión Europea.Publishe

An integrated modelling approach for R5-X4 mutation and HAART therapy assessment

We have modelled the within-patient evolutionary process during HIV infection using different methodologies. New viral strains arise during the course of HIV infection. These multiple strains of the virus are able to use different coreceptors, in particular the CCR5 and the CXCR4 (R5 and X4 phenotypes, respectively)influence the progression of the disease to the AIDS phase. We present a model of HIV early infection and CTLs response which describes the dynamics of R5 quasispecies, specifying the R5 to X4 switch and effects of immune response. We illustrate dynamics of HIV multiple strains in the presence of multidrug HAART therapy. The HAART combined with X4 strain blocker drugs might help to reduce infectivity and lead to slower progression of disease. On the methodology side, our model represents a paradigm of integrating formal methods and mathematical models as a general framework to study HIV multiple strains during disease progression, and will inch towards providing help in selecting among vaccines and drug therapies. The results presented here are one of the rare cases of methodological cross comparison (stochastic and deterministic) and a novel implementation of model checking in therapy validation