Biomechanical analysis of a cranial Patient Specific Implant on the interface with the bone using the Finite Element Method

- New advance technologies based on reverse engineering , design and additive manufacturing, have expanded design capabilities for biomedical applications to include Patient Specific Implants (PSI). This change in design paradigms needs advanced tools to assess the mechanical performance of the product, and simulate the impact on the patient. In this work, we perform a structural analysis on the interface of a cranial PSI under static loading conditions. Based on those simulations, we have identified the regions with high stress and strain and checked the failure criteria both in the implant and the skull. We evaluate the quality of the design of the implant and determine their response given different materials, in order to ensure optimality of the final product to be manufactured

Revista de Vertebrados de la Estación Biológica de Doñana

Descripción de un nuevo género y de una nueva especie Iberocypris palaciosi N.GEN.N.SO (Pisces, cyprinidae).Resultados de los censos d e aves acuáticas en Andalucía Occidental durante el invierno1978-79Interacciones en la alimentación de las larvas de dos especies de tritones. (Triturus marmoratus y Triturus boscai).Utilización del espacio en una comunidad de lacertidos del matorral mediterráneo en la Reserva Biológica de DoñanaMorfología dentaria de las liebres europeas (Lagomorpha, leporidae).El conejo, Oryctolagus cuniculus en Andalucía Occidental: Parámetros corporales y curva de crecimientoObservaciones de foca monje (Monachus monachus Herm.) en las costas del sureste de la Península Ibérica.Presencia de pejerrey Atherina (Hepsetia) boyeri, Risso 1810; Pisces ( Atherinidae) en la laguna de Zoñar (Córdoba, SO de España).Nuevas citas de la "loina" Chondrostoma (Machaerochilus) toxostoma arrigonis Stein. (pisces, cyprinidae) en EspañaRelativa subalimentación de Falco naumanni durante el periodo no reproductor en el valle del GuadalquivirComadrejas alimentandose de carroña.Agrupamientos de Alytes cisternasii bajo el mismo refugioDescripción de un nuevo género de quiróptero neotropical de la familia MolossidaeAlgunas notas sobre Platalea leucorodia en GaliciaInicidencia del murciélago hematófago Desmodus rotundus sobre los indígenas Yanomani de VenezuelaRitmo de actividad de algunos ratones de los llanos de Apure (Venezuela)Presencia del topillo campesino ibérico, Microtus arvalis asturianus Miller, 1908 en la meseta del DueroFalco columbarius EsmerejónCiconia ciconia CigüeñaNycticorax nycticorax MartinetePeer reviewe

First modern human settlement recorded in the Iberian hinterland occurred during Heinrich Stadial 2 within harsh environmental conditions

As the south-westernmost region of Europe, the Iberian Peninsula stands as a key area for understanding the process of modern human dispersal into Eurasia. However, the precise timing, ecological setting and cultural context of this process remains controversial concerning its spatiotemporal distribution within the different regions of the peninsula. While traditional models assumed that the whole Iberian hinterland was avoided by modern humans due to ecological factors until the retreat of the Last Glacial Maximum, recent research has demonstrated that hunter-gatherers entered the Iberian interior at least during Solutrean times. We provide a multi-proxy geoarchaeological, chronometric and paleoecological study on human–environment interactions based on the key site of Peña Capón (Guadalajara, Spain). Results show (1) that this site hosts the oldest modern human presence recorded to date in central Iberia, associated to pre-Solutrean cultural traditions around 26, 000 years ago, and (2) that this presence occurred during Heinrich Stadial 2 within harsh environmental conditions. These findings demonstrate that this area of the Iberian hinterland was recurrently occupied regardless of climate and environmental variability, thus challenging the widely accepted hypothesis that ecological risk hampered the human settlement of the Iberian interior highlands since the first arrival of modern humans to Southwest Europe. © 2021, The Author(s)

First modern human settlement recorded in the Iberian hinterland occurred during Heinrich Stadial 2 within harsh environmental conditions

As the south-westernmost region of Europe, the Iberian Peninsula stands as a key area for understanding the process of modern human dispersal into Eurasia. However, the precise timing, ecological setting and cultural context of this process remains controversial concerning its spatiotemporal distribution within the different regions of the peninsula. While traditional models assumed that the whole Iberian hinterland was avoided by modern humans due to ecological factors until the retreat of the Last Glacial Maximum, recent research has demonstrated that hunter-gatherers entered the Iberian interior at least during Solutrean times. We provide a multi-proxy geoarchaeological, chronometric and paleoecological study on human?environment interactions based on the key site of Peña Capón (Guadalajara, Spain). Results show (1) that this site hosts the oldest modern human presence recorded to date in central Iberia, associated to pre-Solutrean cultural traditions around 26,000 years ago, and (2) that this presence occurred during Heinrich Stadial 2 within harsh environmental conditions. These findings demonstrate that this area of the Iberian hinterland was recurrently occupied regardless of climate and environmental variability, thus challenging the widely accepted hypothesis that ecological risk hampered the human settlement of the Iberian interior highlands since the first arrival of modern humans to Southwest Europe.Tis research was carried out in the context of the ERC MULTIPALEOIBERIA project, funded by the European Research Council (ERC-2018-STG-805478), and the PALEOINTERIOR project, funded by the Spanish Ministry of Science and Innovation (HAR2017-82483-C3-3-P)

J-PLUS DR3: Galaxy-Star-Quasar classification

The Javalambre Photometric Local Universe Survey (J-PLUS) is a 12-band photometric survey using the 83-cm JAST telescope. Data Release 3 includes 47.4 million sources (29.8 million with $r \le 21$) on 3192 deg$^2$ (2881 deg$^2$ after masking). J-PLUS DR3 only provides star-galaxy classification so that quasars are not identified from the other sources. Given the size of the dataset, machine learning methods could provide a valid alternative classification and a solution to the classification of quasars. Our objective is to classify J-PLUS DR3 sources into galaxies, stars and quasars, outperforming the available classifiers in each class. We use an automated machine learning tool called {\tt TPOT} to find an optimized pipeline to perform the classification. The supervised machine learning algorithms are trained on the crossmatch with SDSS DR12, LAMOST DR7 and \textit{Gaia} DR3. We checked that the training set of about 570 thousand galaxies, one million stars and 220 thousand quasars is both representative and pure to a good degree. We considered 37 features: besides the twelve photometric bands with their errors, six colors, four morphological parameters, galactic extinction with its error and the PSF relative to the corresponding pointing. After exploring numerous pipeline possibilities through the TPOT genetic algorithm, we found that XGBoost provides the best performance: the AUC for galaxies, stars and quasars is above 0.99 and the average precision is above 0.99 for galaxies and stars and 0.94 for quasars. XGBoost outperforms the star-galaxy classifiers already provided in J-PLUS DR3 and also efficiently classifies quasars. We also found that photometry was very important in the classification of quasars, showing the relevance of narrow-band photometry.Comment: 14 pages, 17 figure

Research priorities for maintaining biodiversity’s contributions to people in Latin America

Maintaining biodiversity is crucial for ensuring human well-being. The authors participated in a workshop held in Palenque, Mexico, in August 2018, that brought together 30 mostly early-career scientists working in different disciplines (natural, social and economic sciences) with the aim of identifying research priorities for studying the contributions of biodiversity to people and how these contributions might be impacted by environmental change. Five main groups of questions emerged: (1) Enhancing the quantity, quality, and availability of biodiversity data; (2) Integrating different knowledge systems; (3) Improved methods for integrating diverse data; (4) Fundamental questions in ecology and evolution; and (5) Multi-level governance across boundaries. We discuss the need for increased capacity building and investment in research programmes to address these challenges

Bronchoscopist's perception of the quality of the single-use bronchoscope (Ambu aScope4™) in selected bronchoscopies: a multicenter study in 21 Spanish pulmonology services

Background: The disposable bronchoscope is an excellent alternative to face the problem of SARS-CoV-2 and other cross infections, but the bronchoscopist’s perception of its quality has not been evaluated. Methods: To evaluate the quality of the Ambu-aScope4 disposable bronchoscope, we carried out a cross-sectional study in 21 Spanish pulmonology services. We use a standardized questionnaire completed by the bronchoscopists at the end of each bronchoscopy. The variables were described with absolute and relative frequencies, measures of cen‑ tral tendency and dispersion depending on their nature. The existence of learning curves was evaluated by CUSUM analysis. Results: The most frequent indications in 300 included bronchoscopies was bronchial aspiration in 69.3% and the median duration of these was 9.1 min. The route of entry was nasal in 47.2% and oral in 34.1%. The average score for ease of use, image, and aspiration quality was 80/100. All the planned techniques were performed in 94.9% and the bronchoscopist was satisfed in 96.6% of the bronchoscopies. They highlighted the portability and immediacy of the aScope4TM to start the procedure in 99.3%, the possibility of taking and storing images in 99.3%. The CUSUM analysis showed average scores>70/100 from the frst procedure and from the 9th procedure more than 80% of the scores exceeded the 80/100 score

Bronchoscopist's perception of the quality of the single-use bronchoscope (Ambu aScope4™) in selected bronchoscopies : a multicenter study in 21 Spanish pulmonology services

Background: The disposable bronchoscope is an excellent alternative to face the problem of SARS-CoV-2 and other cross infections, but the bronchoscopist's perception of its quality has not been evaluated. Methods: To evaluate the quality of the Ambu-aScope4 disposable bronchoscope, we carried out a cross-sectional study in 21 Spanish pulmonology services. We use a standardized questionnaire completed by the bronchoscopists at the end of each bronchoscopy. The variables were described with absolute and relative frequencies, measures of central tendency and dispersion depending on their nature. The existence of learning curves was evaluated by CUSUM analysis. Results: The most frequent indications in 300 included bronchoscopies was bronchial aspiration in 69.3% and the median duration of these was 9.1 min. The route of entry was nasal in 47.2% and oral in 34.1%. The average score for ease of use, image, and aspiration quality was 80/100. All the planned techniques were performed in 94.9% and the bronchoscopist was satisfied in 96.6% of the bronchoscopies. They highlighted the portability and immediacy of the aScope4TM to start the procedure in 99.3%, the possibility of taking and storing images in 99.3%. The CUSUM analysis showed average scores > 70/100 from the first procedure and from the 9th procedure more than 80% of the scores exceeded the 80/100 score. Conclusions: The aScope4™ scored well for ease of use, imaging, and aspiration. We found a learning curve with excellent scores from the 9th procedure. Bronchoscopists highlighted its portability, immediacy of use and the possibility of taking and storing images