2,554 research outputs found

    The Death Knell For the Death Penalty and the Significance of Global Realism to its Abolition from Glossip v. Gross to Brumfield v. Cain

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    Objectives For the last decade a host of different projects have been launched to allow persons who are concerned about their hearing status to quickly and at a low cost test their hearing ability. Most often, this is carried out without collecting complementary information that could be correlated with hearing impairment. In this two-part study we first, present the development and validation of a novel Internet-based hearing test, and second, report on the associations between this test and phonological representation, quality of life and self-reported hearing difficulties. Design Cross-sectional study. Setting An opportunity sample of participants was recruited at the Stockholm central station for the first study. All parts of the second study were conducted via the Internet, with testing and self-report forms adapted for online use. Participants The first part of the study was carried out in direct contact with the participants, and participants from the second study were recruited by means of advertisements in newspapers and on webpages. The only exclusion criterion was that participants had to be over 18 years old. Most participants were between 60 and 69 years old. There were almost an equal number of men and women (total n=316). Outcome measures 48 participants failed the Internet-based hearing screening test. The group failing the test reported more problems on the Amsterdam Inventory of Auditory Disability. In addition, they were found to have diminished phonological representational skills. However, no difference in quality of life was found. Conclusions Almost one in five participants was in need of contacting their local hearing clinic. This group had more complaints regarding tinnitus and hyperacusis, rated their own hearing as worse than those who passed, and had a poorer capability of generating accurate phonological representations. This study suggests that it is feasible to screen for hearing status online, and obtain valid data

    Physical contact in physical education, sports coaching and the preschool – a scoping review

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    Physical contact between adults and children in educational setting has been a well debated subject in research over the past 20 years. Although physical contact is often regarded as an important pedagogical tool, it has given rise to an increased awareness amongst sports coaches, physical education and preschool teachers about the possible negative consequences of its use in these settings. The aim of this article is to map the current literature on physical contact in physical education, sports coaching and the preschool and identify research gaps by means of a scoping review, i.e. after 20 years of research in the field of intergenerational touch what can be said to be known in the field and what possible gaps are there in the research? The research questions are: (i) Which journals, countries, settings, theories and methods are represented in the research field? (ii) Which central themes and knowledge gaps can be identified? The results show that the research field has expanded significantly in the last 20 years, both in terms of the number of published articles, the number of countries represented in the research and the number of journals in which articles on the topic have been published. The central themes identified in the articles included in the review cover the following topics: fears related to physical contact, resistance, cultural differences, the functions and needs of physical contact and the professional identity of sports coaches, physical education and preschool teachers. It is concluded that studies that could lead the research field forward would ideally focus on intersectionality, or how practitioners’ fears of physical contact impact their pedagogical work with students.Physical contact in physical education, sports coaching and the preschool – a scoping reviewpublishedVersio

    Increased T cell breadth and antibody response elicited in prime-boost regimen by viral vector encoded homologous SIV Gag/Env in outbred CD1 mice

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    BACKGROUND: A major obstacle for the development of HIV vaccines is the virus’ worldwide sequence diversity. Nevertheless, the presence of T cell epitopes within conserved regions of the virus’ structural Gag protein and conserved structures in the envelope (env) sequence raises the possibility that cross-reactive responses may be induced by vaccination. In this study, the aim was to investigate the importance of antigenic match on immunodominance and breadth of obtainable T cell responses. METHODS: Outbred CD1 mice were immunized with either heterologous (SIVmac239 and HIV-1 clade B consensus) or homologous (SIVmac239) gag sequences using adenovirus (Ad5) and MVA vectors. Env (SIVmac239) was co-encoded in the vectors to study the induction of antibodies, which is a primary target of current HIV vaccine designs. All three vaccines were designed as virus-encoded virus-like particle vaccines. Antibody responses were analysed by ELISA, avidity ELISA, and neutralization assay. T cell responses were determined by intracellular cytokine staining of splenocytes. RESULTS: The homologous Env/Gag prime-boost regimen induced higher Env binding antibodies, and induced stronger and broader Gag specific CD8+ T cell responses than the homologous Env/heterologous Gag prime-boost regimen. Homologous Env/heterologous Gag immunization resulted in selective boosting of Env specific CD8+ T cell responses and consequently a paradoxical decreased recognition of variant sequences including conserved elements of p24 Gag. CONCLUSIONS: These results contrast with related studies using Env or Gag as the sole antigen and suggest that prime-boost immunizations based on homologous SIVmac239 Gag inserts is an efficient component of genetic VLP vaccines—both for induction of potent antibody responses and cross-reactive CD8+ T cell responses

    Institutional Dynamics in a Re-ordering World

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    The chapters in this volume point to a profound re-definition of structuring frames for action and of normative and cognitive reference sets. All chapters, individually and as a whole, document in other words significant institutional transformation. The transnationalization of our world, sometimes hastily labeled “globalization”, is not only – and far from it – about flows of goods, capital or people. Nor is transnationalization simply a discourse even though it does have important discursive dimensions. Our transnationalizing world is a re-ordering world, a world where institutional rules of the game are in serious transition. Furthermore, the chapters in this volume clearly suggest – and many mundane contemporary experiences confirm it – that the impact of re-ordering processes is significant and consequential for our everyday lives. [First paragraph

    Welfare of Atlantic salmon in closed and open systems

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    Akvakultur Ă€r den snabbast vĂ€xande animalieproduktionen i vĂ€rlden. År 2016 producerades 80 miljoner ton matfisk varav atlantlax utgjorde 4 %. Norge Ă€r vĂ€rldens största laxproducent och producerar ca 1,2 miljoner ton matfisk per Ă„r. Den stora ökningen har delvis lett till ett ökat intresse för fiskars vĂ€lfĂ€rd. Syftet med litteraturstudien Ă€r att identifiera fyra relevanta vĂ€lfĂ€rdsindikatorer och jĂ€mföra dess implikation hos atlantlax i tvĂ„ olika produktionssystem; recirkulerande akvakultursystem (RAS) och kasse. För att kunna mĂ€ta vĂ€lfĂ€rd behövs en definition samt vĂ€lfĂ€rdsindikatorer som kan mĂ€ta hur fiskens vĂ€lfĂ€rdsbehov tillgodoses. Fyra vĂ€lfĂ€rdsindikatorer har undersökts; dödlighet, tillvĂ€xt, temperatur och densitet. I jĂ€mförelse med kasse var tillvĂ€xten högre i RAS och temperaturen kunde lĂ€ttare anpassas efter laxens behov. Dödligheten och densiteten var dĂ€remot högre i RAS vilket kan anses vara negativt för fiskens vĂ€lfĂ€rd. NĂ€r det gĂ€ller huruvida vĂ€lfĂ€rdsbehoven har tillgodosetts i de tvĂ„ systemen uppfyllde RAS temperatur och tillvĂ€xt i högre grad Ă€n kasse medan kasse var bĂ€ttre lĂ€mpat för laxen gĂ€llande dödlighet och densitet. Valet av indikatorer och studier kan ha pĂ„verkat det slutliga utfallet och det Ă€r dĂ€rmed svĂ„rt att avgöra vilket system som faktiskt erbjuder bĂ€sta vĂ€lfĂ€rden för atlantlaxen. Min hypotes om att kasse skulle uppfylla vĂ€lfĂ€rdsbehoven i högre grad Ă€n RAS stĂ€mde dĂ€rmed delvis.Aquaculture is globally the fastest growing animal production sector. It is important to study the fish welfare in the production. The main purpose with this litterature review is to adress four important welfare indicators of Atlantic salmon, and compare the welfare in two different production systems; recirculating aquaculture systems (RAS) and net-pens. In order to measure welfere, a definition is needed and welfare indicators that can assess the welfare of the fish. Four indicators was chosen; mortality, growth, temperature and stocking density. Growth was better in RAS as well as the ability to optimize the water temperature. Mortality and stocking density was also higher in RAS which could inply lower welfare in RAS compared to net-pens. About the fulfillment of the welfare needs in the two systems, RAS was better suited for the salmon in the aspect of growth and temperature while net-pen was better in the aspect of mortality and stocking density. My hypothesis that net-pens would be better suited for fish welfare was partly correct

    Fasta körspÄr till framtiden

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    Uppsatsen har skrivits pĂ„ uppdrag av Lena Holm och Johan Arvidsson. Denna studie Ă€r en del av deras stora forskningsprojekt ”Fasta körspĂ„r- skördepotential och effekt pĂ„ markstruktur” med ett lĂ„ngliggande försök som startades Ă„r 2010. Bakgrunden till denna studie Ă€r att klimatet stĂ€ndigt förĂ€ndras och jordens medeltemperatur stiger, vilket leder till brist pĂ„ vatten i stora omrĂ„den i vĂ€rlden. Det förĂ€ndrade klimatet har lett till ett allt mer extremt tillstĂ„nd med kraftiga regn och extrem torka runt om i vĂ€rlden. Med dagens moderna odlingsmetoder kan odling i allt mer utsatta omrĂ„den existera Ă€ven i framtiden, men det krĂ€ver en förĂ€ndring och en ökad kunskap kring olika tekniker. NĂ€r regnet blir allt mer extremt mĂ„ste det ocksĂ„ till ett odlingssystem som Ă€r mer anpassat efter dessa extrema mĂ€ngder nederbörd. Det kan vara genom till exempel bĂ€ttre förmĂ„ga att infiltrera de stora mĂ€ngderna vatten under kortare tid Ă€n idag. I stora odlingslĂ€nder som Australien i vĂ€rlden blir reducerad bearbetning eller "no-till" (direktsĂ„dd) allt vanligare dĂ„ kostnaderna stĂ€ndigt jagas samtidigt som detta lett till ett mer hĂ„llbart sĂ€tt att bruka jorden pĂ„. Dagens maskiner Ă€r allt oftare utrustade med GPSteknik som hjĂ€lper lantbrukare i vĂ€rlden att bruka jorden pĂ„ ett mer effektivt och resurssparande sĂ€tt. Med tekniken kan överlappet minskas, vilket ger en positiv effekt i form av minskade insatser sĂ„ som diesel utsĂ€de och vĂ€xtnĂ€ring. GPS-tekniken har lett till att man pĂ„ stora brukningsarealer provat att centrera körspĂ„ren för att minimera den trafikerade ytan pĂ„ fĂ€ltet och dĂ€r igenom reducera packningsskadornas omfattning. Syftet med studien var att undersöka om markstrukturen pĂ„verkades positivt av att körspĂ„ren koncentrerades i jĂ€mförelse med om marken trafikerades slumpmĂ€ssigt. Den syftade ocksĂ„ till att jĂ€mföra effekterna mellan olika bearbetningsmetoder. De parametrar som undersöktes i studien Ă€r skrymdensitet och infiltration. Studiens avgrĂ€nsningar var att prover endast togs ut ur matjordslagret pĂ„ 10 till 15 cm djup. Endast ett försök under ett Ă„r ingĂ„r. Skördeeffekter behandlades inte i denna studie. I resultatet av studien framkom att det fanns skillnader mellan olika bearbetningsmetoder, bĂ„de för skrymdensitet och infiltration. Det fanns nĂ„gra behandlingar som skiljer sig signifikant frĂ„n de andra. Tydligt framkom att direktsĂ„dd gav en högre skrymdensitet, vilket tyder pĂ„ en mer kompakt jord. Inga signifikanta skillnader kunde urskiljas mellan den konventionella trafikeringsmetoden och fasta körspĂ„rs spĂ„rfria yta. För infiltrationsresultaten visade det att det fanns signifikanta skillnader mellan de olika bearbetningsmetoderna. Konventionellt trafikerad direktsĂ„dd var den bearbetningsmetoden som skiljde sig signifikant genom de mycket lĂ„ga vĂ€rdena för infiltration. Dock fanns det inga signifikanta skillnader mellan de olika trafikeringsmetoderna. I diskussionen jĂ€mfördes resultaten med riktvĂ€rden. För skrymdensitet lĂ„g alla resultatsvĂ€rden bra till i förhĂ„llande till riktvĂ€rdena. För infiltration var variationen större, frĂ„n 1,3 cm till 10,2 cm/timme. Men trots det var alla vĂ€rden Ă€ven hĂ€r inom ramen för riktvĂ€rdena. Infiltration och skrymdensitet Ă€r tvĂ„ parametrar som pĂ„verkar varandra mycket. Om jorden Ă€r kompakt kommer den heller inte att infiltrera tillfredstĂ€llande och om jorden inte infiltrerat vattnet kommer grödorna att ta skada vilket Ă€ven sker nĂ€r jorden Ă€r för kompakt dĂ„ bland annat rottillvĂ€xten hĂ€mmas och grödan pĂ„verkas negativt.This essay is written at the request of Lena Holm and Johan Arvidsson. The study is a part of their major research project “Control traffic- harvest potential and effects on soil structure” with long-term trails that stated up in year 2010. The background of this study is that the climate is changing constantly and the global temperature increases. The result of this is less water in some parts of the world (too dry) and at the same time water flooding in another part of the world. Rainfall becomes more heavy when it comes. Modern tillage methods (without plow) are increasing in the world. The cropping system must be prepared for the future climate to infiltrate a lot of rain water and at the same time take care of the soil water. In bigger countries as Australia, no-till is a common tillage system. Today itÂŽs important to look after the costs relative to input materials like diesel, nutrients and manpower. GPS has taken the world further, to help minimize these costs in terms of overlapping. The “controlled traffic farming” is one way in the direction with permanent trumlines every year. Through this the traffic area decreases and minimizes the risk of soil compaction from modern heavy machines. The aim of the study was to investigate if the soil structure were influenced positively if the tramlines were fixed compared with conventional trafficking (CTF). It also intended to consider if there is any differences between different cultivation methods. The studied parameters were bulk density and infiltration in the profile (10-15cm deep). The result showed that there were differences between tillage methods both for bulk density and infiltration. In the conventional traffic, no-till has the highest bulk density, which means that it is very compact. In general the no-till treatments were more compact than the other treatments. There were no significant differences between tillage methods and traffic models. The infiltration result shows that there were significant differences between the different tillage methods. The conventional no-till system has the significantly lowest infiltrations capacity. But there is not differences between tillage methods and traffic methods. The discussion part of the essay compares the results with benchmark values (a indicator value). This shows that all of the results from the study are within the frame, none of them are too high or too low. The bulk density results are all within the frame of value. The infiltration value has greater variety, from 1,3 - 10,2 cm/hour. Even though, they were all within the frame. The infiltration and the bulk density interact. If the soil is compact it will not infiltrate. If the water stays on the surface, it will destroy the crop in flooding. And if the soil is too compact the root growth will be inhibited which then inhibits the plant

    Betydelsen av bÀrbara elektroniska hjÀlpmedel för barn med kognitiv funktionsnedsÀttning och deras familjer

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    The aim of this study was to describe how families with children, having cognitive disabilities, interacted with portable electronic assistive devices in their daily life. More specifically, its aim was to study the needs for families when they decided to use electronic assistive devices as assistance in their everyday lives, what everyday function they added value to and if they had the same meaning for children and parents. The study was based on ten interviews with family members from four families, where the children had began to use Handi or iPhone as cognitive assistance. Categories were identified and from those, eight themes were created that played important roles in the everyday lives of the families. The analyses were based on the indivduals’ experiences of their portable electronic assistive devices. The teoretical perspective is Salutogenetic perspectiv and KASAM. The interwied parents expected the electronic assisitive devices to strengthen the children's sense of coherence and increase their participation, autonomy and equality to children of the same age. The parents expressed that assistive devices were a resource for both the children and themselves as they made the children more independent, having taking over the role of everyday reminding. That resulted in lower stress levels, less anxiety and less conflicts in the families. The family situation as a whole developed in a positive direction. There was a high degree of agreement among the children and parents regarding the importance of the electronic assistive devices. This study gives a clear indication that children®s needs can not be classified by just looking at age or development, they have to be seen in their context, the family. The needs of the whole family has to be considered in order to promote the wellbeing and development of the children
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