2,630 research outputs found
Ultracompact X-ray Binaries in Globular Clusters: Variability of the Optical Counterpart of X1832-330 in NGC 6652
Evidence is emerging that the luminous X-ray sources in the cores of globular
clusters may often consist of, or perhaps even as a class be dominated by,
ultracompact (P < 1 hr) binary stars. To the two such systems already known, in
NGC 6624 and NGC 6712, we now add evidence for two more. We detect large
amplitude variability in the candidate optical counterpart for the X-ray source
in the core of NGC 6652. Although the available observations are relatively
brief, the existing Hubble Space Telescope data indicate a strong 43.6 min
periodic modulation of the visible flux of semi-amplitude 30%. Further,
although the orbital period of the source in NGC 1851 is not yet explicitly
measured, we demonstrate that previous correlations of optical luminosity with
X-ray luminosity and accretion disk size, strengthened by recent data, strongly
imply that the period of that system is also less than 1 hr. Thus currently
there is evidence that 4 of the 7 globular cluster X-ray sources with
constrained periods are ultracompact, a fraction far greater than that found in
X-ray binaries the field.Comment: 10 pages including 2 figures and 1 table. Accepted for publication in
The Astrophysical Journal Letter
Comparative population structure of <i>Plasmodium malariae</i> and <i>Plasmodium falciparum</i> under different transmission settings in Malawi
<b>Background:</b> Described here is the first population genetic study of Plasmodium malariae, the causative agent of quartan malaria. Although not as deadly as Plasmodium falciparum, P. malariae is more common than previously thought, and is frequently in sympatry and co-infection with P. falciparum, making its study increasingly important. This study compares the population parameters of the two species in two districts of Malawi with different malaria transmission patterns - one seasonal, one perennial - to explore the effects of transmission on population structures.
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<b>Methods:</b> Six species-specific microsatellite markers were used to analyse 257 P. malariae samples and 257 P. falciparum samples matched for age, gender and village of residence. Allele sizes were scored to within 2 bp for each locus and haplotypes were constructed from dominant alleles in multiple infections. Analysis of multiplicity of infection (MOI), population differentiation, clustering of haplotypes and linkage disequilibrium was performed for both species. Regression analyses were used to determine association of MOI measurements with clinical malaria parameters.
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<b>Results:</b> Multiple-genotype infections within each species were common in both districts, accounting for 86.0% of P. falciparum and 73.2% of P. malariae infections and did not differ significantly with transmission setting. Mean MOI of P. falciparum was increased under perennial transmission compared with seasonal (3.14 vs 2.59, p = 0.008) and was greater in children compared with adults. In contrast, P. malariae mean MOI was similar between transmission settings (2.12 vs 2.11) and there was no difference between children and adults. Population differentiation showed no significant differences between villages or districts for either species. There was no evidence of geographical clustering of haplotypes. Linkage disequilibrium amongst loci was found only for P. falciparum samples from the seasonal transmission setting.
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<b>Conclusions:</b> The extent of similarity between P. falciparum and P. malariae population structure described by the high level of multiple infection, the lack of significant population differentiation or haplotype clustering and lack of linkage disequilibrium is surprising given the differences in the biological features of these species that suggest a reduced potential for out-crossing and transmission in P. malariae. The absence of a rise in P. malariae MOI with increased transmission or a reduction in MOI with age could be explained by differences in the duration of infection or degree of immunity compared to P. falciparum
Renovating Pastures with Glyphosate Tolerant Soybeans
Pasture renovation is expensive because of lost production, costs for eliminating existing vegetation by tillage or herbicides, and direct replanting costs. Reducing costs, reducing risk of failure, and producing income from pasture land during renovation can significantly increase the profitability of improving pastures
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Sensitivity of terrestrial precipitation trends to the structural evolution of sea surface temperatures
Pronounced intermodel differences in the projected response of land surface precipitation (LSP) to future anthropogenic forcing remain in the Coupled Model Intercomparison Project Phase 5 model integrations. A large fraction of the intermodel spread in projected LSP trends is demonstrated here to be associated with systematic differences in simulated sea surface temperature (SST) trends, especially the representation of changes in (i) the interhemispheric SST gradient and (ii) the tropical Pacific SSTs. By contrast, intermodel differences in global mean SST, representative of differing global climate sensitivities, exert limited systematic influence on LSP patterns. These results highlight the importance to regional terrestrial precipitation changes of properly simulating the spatial distribution of large-scale, remote changes as reflected in the SST response to increasing greenhouse gases. Moreover, they provide guidance regarding which region-specific precipitation projections may be potentially better constrained for use in climate change impact assessments
Infrared Candidates for the Intense Galactic X-ray Source GX 17+2
We present new astrometric solutions and infrared Hubble Space Telescope
observations of GX 17+2 (X1813-140), one of the brightest X-ray sources on the
celestial sphere. Despite 30 years of intensive study, and the existence of a
strong radio counterpart with a sub-arcsecond position, the object remains
optically unidentified. The observed X-ray characteristics strongly suggest
that it is a so-called "Z-source," the rare but important category that
includes Sco X-1 and Cyg X-2. Use of the USNO-A2.0 catalog enables us to
measure the position of optical and infrared objects near the radio source to
sub-arcsecond precision within the International Celestial Reference Frame, for
direct comparison with the radio position, which we also recompute using modern
calibrators. With high confidence we eliminate the V~17.5 star NP Ser, often
listed as the probable optical counterpart of the X-ray source, as a candidate.
Our HST NICMOS observations show two faint objects within our 0.5" radius 90%
confidence error circle. Even the brighter of the two, Star A, is far fainter
than expected (H~19.8), given multiple estimates of the extinction in this
field and our previous understanding of Z sources, but it becomes the best
candidate for the counterpart of GX 17+2. The probability of a chance
coincidence of an unrelated faint object on the radio position is high.
However, if the true counterpart is not Star A, it is fainter still, and our
conclusion that the optical counterpart is surprisingly underluminous is but
strengthened.Comment: 15 pages including 3 figures and 3 tables. Accepted for publication
in The Astrophysical Journa
The promise and peril of intensive-site-based ecological research: insights from the Hubbard Brook ecosystem study
Abstract.
Ecological research is increasingly concentrated at particular locations or sites. This trend reflects a variety of advantages of intensive, site-based research, but also raises important questions about the nature of such spatially delimited research: how well does site based research represent broader areas, and does it constrain scientific discovery?We provide an overview of these issues with a particular focus on one prominent intensive research site: the Hubbard Brook Experimental Forest (HBEF), New Hampshire, USA. Among the key features of intensive sites are: long-term, archived data sets that provide a context for new discoveries and the elucidation of ecological mechanisms; the capacity to constrain inputs and parameters, and to validate models of complex ecological processes; and the intellectual cross-fertilization among disciplines in ecological and environmental sciences. The feasibility of scaling up ecological observations from intensive sites depends upon both the phenomenon of interest and the characteristics of the site. An evaluation of deviation metrics for the HBEF illustrates that, in some respects, including sensitivity and recovery of streams and trees from acid deposition, this site is representative of the Northern Forest region, of which HBEF is a part. However, the mountainous terrain and lack of significant agricultural legacy make the HBEF among the least disturbed sites in the Northern Forest region. Its relatively cool, wet climate contributes to high stream flow compared to other sites. These similarities and differences between the HBEF and the region can profoundly influence ecological patterns and processes and potentially limit the generality of observations at this and other intensive sites. Indeed, the difficulty of scaling up may be greatest for ecological phenomena that are sensitive to historical disturbance and that exhibit the greatest spatiotemporal variation, such as denitrification in soils and the dynamics of bird communities. Our research shows that end member sites for some processes often provide important insights into the behavior of inherently heterogeneous ecological processes. In the current era of rapid environmental and biological change, key ecological responses at intensive sites will reflect both specific local drivers and regional trends
Geochemical Logging in the Cajon Pass Drill Hole and Its Application to a New, Oxide, Igneous Rock Classification Scheme
A new elemental oxide classification scheme for crystalline rocks is developed and applied to geochemical well logs from the Cajon Pass drill hole. This classification scheme takes advantage of measurements of elements taken by a geochemical logging tool string. It uses K_2O versus SiO_2/Al_2O_3 to distinguish between granites, granodiorites, tonalites, syenites, monzonites, diorites, and gabbros. Oxide measurements from cores are used to calibrate the elemental abundances determined from the well logs. From these logs, a detailed lithologic column of the core is generated. The lithologic column derived from the well log classification scheme is compared with a lithologic column constructed from core samples and well cuttings. In the upper 1295 m of the well, agreement between the two columns is good. Discrepancies occur from 1295 to 2073 m and are believed to be caused by the occurrence of rock types not distinguished by the classification scheme and/or the occurrence of secondary minerals. Despite these discrepancies, the well log-based classification scheme helps to distinguish changes in rock type and shows potential as an aid to the construction of lithologic columns in boreholes of crystalline rocks
Monoamine Oxidase is a Major Determinant of Redox Balance in Human Atrial Myocardium and is Associated With Postoperative Atrial Fibrillation
BACKGROUND:
Onset of postoperative atrial fibrillation (POAF) is a common and costly complication of heart surgery despite major improvements in surgical technique and quality of patient care. The etiology of POAF, and the ability of clinicians to identify and therapeutically target high-risk patients, remains elusive.
METHODS AND RESULTS:
Myocardial tissue dissected from right atrial appendage (RAA) was obtained from 244 patients undergoing cardiac surgery. Reactive oxygen species (ROS) generation from multiple sources was assessed in this tissue, along with total glutathione (GSHt) and its related enzymes GSH-peroxidase (GPx) and GSH-reductase (GR). Monoamine oxidase (MAO) and NADPH oxidase were observed to generate ROS at rates 10-fold greater than intact, coupled mitochondria. POAF risk was significantly associated with MAO activity (Quartile 1 [Q1]: adjusted relative risk [ARR]=1.0; Q2: ARR=1.8, 95% confidence interval [CI]=0.84 to 4.0; Q3: ARR=2.1, 95% CI=0.99 to 4.3; Q4: ARR=3.8, 95% CI=1.9 to 7.5; adjusted Ptrend=0.009). In contrast, myocardial GSHt was inversely associated with POAF (Quartile 1 [Q1]: adjusted relative risk [ARR]=1.0; Q2: ARR=0.93, 95% confidence interval [CI]=0.60 to 1.4; Q3: ARR=0.62, 95% CI=0.36 to 1.1; Q4: ARR=0.56, 95% CI=0.34 to 0.93; adjusted Ptrend=0.014). GPx also was significantly associated with POAF; however, a linear trend for risk was not observed across increasing levels of the enzyme. GR was not associated with POAF risk.
CONCLUSIONS:
Our results show that MAO is an important determinant of redox balance in human atrial myocardium, and that this enzyme, in addition to GSHt and GPx, is associated with an increased risk for POAF. Further investigation is needed to validate MAO as a predictive biomarker for POAF, and to explore this enzyme's potential role in arrhythmogenesis
LASE Measurements of Water Vapor, Aerosol, and Cloud Distributions in Saharan Air Layers and Tropical Disturbances
LASE (Lidar Atmospheric Sensing Experiment) onboard the NASA DC-8 was used to measure high resolution profiles of water vapor and aerosols, and cloud distributions in 14 flights over the eastern Atlantic region during the NAMMA (NASA African Monsoon Multidisciplinary Analyses) field experiment, which was conducted from August 15 to September 12, 2006. These measurements were made in conjunction with flights designed to study African Easterly Waves (AEW), Tropical Disturbances (TD), and Saharan Aerosol Layers (SALs) as well as flights performed in clear air and convective regions. As a consequence of their unique radiative properties and dynamics, SAL layers have a significant influence in the development of organized convection associated with TD. Interactions of the SAL with tropical air during early stages of the development of TD were observed. These LASE measurements represent the first simultaneous water vapor and aerosol lidar measurements to study the SAL and its impact on TDs and hurricanes. Seven AEWs were studied and four of these evolved into tropical storms and three did not. Three out of the four tropical storms evolved into hurricanes
The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting
Background: Chronic obstructive pulmonary disease (COPD) is a known predictor of decreased long-term survival after coronary artery bypass grafting (CABG). Differences in survival by race have not been examined.
Methods: A retrospective cohort study was conducted of CABG patients between 2002 and 2011. Long-term survival was compared in patients with and without COPD and stratified by race. Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model.
Results: A total of 984 (20%) patients had COPD (black n = 182; white n = 802) at the time of CABG (N = 4,801). The median follow-up for study participants was 4.4 years. COPD was observed to be a statistically significant predictor of decreased survival independent of race following CABG (no COPD: HR = 1.0; white COPD: adjusted HR = 1.9, 95% CI = 1.7–2.3; black COPD: adjusted HR = 1.6, 95% CI = 1.1–2.2).
Conclusion: Contrary to the expected increased risk of mortality among black COPD patients in the general population, a similar survival disadvantage was not observed in our CABG population
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