The effects of farmer attitudes and farm management practices on soil quality: a study in Cherokee County, Iowa

This study seeks to relate farmer attitudes, perceptions, and management characteristics to field soil quality and laboratory fertility indicators. Farmer interviews were conducted to document recent practices on the farm as well as farmer attitudes about farming. To obtain soil quality measures, both the Natural Resource Conservation Service\u27s field soil quality kit and laboratory tests were employed. Sites from the eastern half of Cherokee County, Iowa, were selected.;Key considerations of this study included farmer practices of renting versus owning land and organic or synthetic nitrogen application. Additional farmer data, including attitudes about farming, are used in this analysis.;In our study, farmers with longer farming experience had access to larger acreages. Also farmers with larger farms tended to adopt no till systems. When asked how they would change their operation if provided with unlimited resources, farmers who make decisions based upon simplicity and economics are more likely to continue their operation as is, while those who use experience, trial and error, as well as experimentation as their primary decision making tools are more likely to scale back their operations.;It was observed that ownership was not directly an influencing factor in shaping soil quality. However, some of the farmers\u27 traits and attributes led to management activities that significantly impacted selected soil quality and fertility indices. The use of organic and inorganic amendments had not led to significantly different potassium or phosphorus levels in the fields. Fields of farmers with large acreages had lower microbial respiration and higher pH. The no-till systems adopted by farmers with large acreages were associated with soils with higher bulk density. Farmers who viewed farming as only labor or management had fields with higher bulk densities and nitrate levels than those who viewed farming as a multifaceted profession. Additionally, farmers who enjoyed farming had fields with lower bulk densities than those who farmed simply to make a living

Soils of the Central Nebraska Loess Hills and Central Loess Plains

Understanding soil systems that characterize a region is critical to natural resource management. However, the knowledge gained through intensive study of local soil systems, which takes place annually as part of collegiate soil judging contests, is often poorly preserved for future use. In this study, field descriptions and laboratory data for 16 soil profiles described for the 2019 Region 5 Soil Judging Contest were used to characterize the soil system of the Central Nebraska Loess Hills and Central Loess Plains. Three landscape components of this soil system were analyzed: the loess uplands and rainwater basins, the transitional zone, and bottomlands. Rainwater basins exhibit increasing clay, clay films, and melanization compared to surrounding uplands. The transitional zone between the upland and bottomlands exhibits fining and aging of parent material with increasing elevation, resulting in increased prevalence of clay films, lower pH relative to parent material, and melanization. The bottomlands exhibited subtle variations in texture of the alluvium resulting in differences in expression of melanization, effervescence, pH, and redoximorphic features. Patterns observed within this soil system are well explained by existing pedogenic theories and demonstrate the unique interplay between soil-forming factors characteristic of this region of the Great Plains

The Possible Application of Ketamine in the Treatment of Depression in Alzheimer\u27s Disease

Depression is a leading cause of disability globally, with a prevalence of 3.8% among the whole population, 5% of the adult population, and 5.7% of the elderly population over 60 years of age. There is evidence that depression is linked to certain neurodegenerative diseases, one being Alzheimer\u27s disease (AD). The efficacy of conventional antidepressants to treat depression in AD is conflicting, especially regarding selective serotonin reuptake inhibitors (SSRIs). A recent systemic review and meta-analysis of 25 randomized controlled trials including fourteen antidepressant medications showed no high efficacy in treating AD patients\u27 symptoms. However, ketamine, a nonselective N-methyl-D-aspartate (NMDA) receptor antagonist, can mediate a wide range of pharmacological effects, including neuroprotection, anti-inflammatory and anticancer properties, multimodal analgesia, and treatment of depression, suicidal attempts, and status epilepticus. Esketamine, which is ketamine formulated as a nasal spray, was approved by the Federal Drug Administration (FDA) in March 2019 as an adjuvant drug to treat treatment-resistant depression. NMDA receptor antagonists treat AD through offsetting AD-related pathological stimulation of subtypes of glutamate receptors in the central nervous system. Recent clinical findings suggest that ketamine may provide neuroprotection and reduce neuropsychiatric symptoms associated with AD. In the present investigation, we evaluate the potential role of ketamine and its postulated mechanism in AD management

Alexa?: Possibilities of Voice Assistant Technology and Artificial Intelligence in the Classroom

The following paper represents the combined effort of 10 educators exploring the experience and use of voice assistant technology in classrooms. This reflection and study of our classrooms looks to better understand both our use of technology and students’ use of technology in very specific ways. Is there a place for voice assistant technology in our classrooms? What benefits are there? What obstacles exist? We tell our stories and experiences here with the intent to provide context and continue the discussion among more of our colleagues

A Cytochrome b561 with Ferric Reductase Activity from the Parasitic Blood Fluke, Schistosoma japonicum

Parasites acquire their food from their hosts, either by feeding directly on tissues of the host, or by competing for ingested food. Adult schistosomes live within the vasculature of humans and rely on the blood cells and plasma they ingest and dissolved solutes they derive across their body surface, the tegument, for their nutrition. Schistosomes require host trace elements, notably iron, which is used as a co-factor in many biological reactions. Iron is especially important for schistosomes, for it has a significant role in egg formation and embryogenesis. In human tissues, iron predominates in the trivalent (ferric) form; however, it is the divalent (ferrous) form that is used as an essential co-factor for multiple biomolecules and enzymes. In order to be acquired from the host environment, the valency of iron must be modified to render it suitable for transport across the parasite membrane. This paper describes the molecular characterisation of a schistosome molecule that is crucial for bringing about this change in iron. Schistosoma japonicum Cytb561 is the first ferric reductase characterised in any parasitic helminth and emphasises the importance of iron, and other divalent cations, in these organisms

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention

OBJECTIVES: This multicenter pragmatic investigation assessed outcomes following clinical implementation of CYP2C19 genotype-guided antiplatelet therapy after percutaneous coronary intervention (PCI). BACKGROUND: CYP2C19 loss-of-function alleles impair clopidogrel effectiveness after PCI. METHODS: After clinical genotyping, each institution recommended alternative antiplatelet therapy (prasugrel, ticagrelor) in PCI patients with a loss-of-function allele. Major adverse cardiovascular events (defined as myocardial infarction, stroke, or death) within 12 months of PCI were compared between patients with a loss-of-function allele prescribed clopidogrel versus alternative therapy. Risk was also compared between patients without a loss-of-function allele and loss-of-function allele carriers prescribed alternative therapy. Cox regression was performed, adjusting for group differences with inverse probability of treatment weights. RESULTS: Among 1,815 patients, 572 (31.5%) had a loss-of-function allele. The risk for major adverse cardiovascular events was significantly higher in patients with a loss-of-function allele prescribed clopidogrel versus alternative therapy (23.4 vs. 8.7 per 100 patient-years; adjusted hazard ratio: 2.26; 95% confidence interval: 1.18 to 4.32; p = 0.013). Similar results were observed among 1,210 patients with acute coronary syndromes at the time of PCI (adjusted hazard ratio: 2.87; 95% confidence interval: 1.35 to 6.09; p = 0.013). There was no difference in major adverse cardiovascular events between patients without a loss-of-function allele and loss-of-function allele carriers prescribed alternative therapy (adjusted hazard ratio: 1.14; 95% confidence interval: 0.69 to 1.88; p = 0.60). CONCLUSIONS: These data from real-world observations demonstrate a higher risk for cardiovascular events in patients with a CYP2C19 loss-of-function allele if clopidogrel versus alternative therapy is prescribed. A future randomized study of genotype-guided antiplatelet therapy may be of value