193 research outputs found

    The Man Who Married a Dumb Wife (November 19, 1954)

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    Program for The Man Who Married a Dumb Wife (November 19, 1954)

    Le Jongleur de Notre Dame (The Juggler of Our Lady)

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    This is a limited edition of the french-language version of The Juggler of Our Lady by Anatole France (1844-1924). The story was adapted from a medieval poem by the Nobel-winning writer in 1890 and published as a book in 1906. The manuscript includes illustrations and calligraphy by Henri Malteste (1881-1961) or “Malateste.https://ecommons.udayton.edu/ul_rare_books/1014/thumbnail.jp

    Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome associated with COVID-19: An Emulated Target Trial Analysis.

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    RATIONALE: Whether COVID patients may benefit from extracorporeal membrane oxygenation (ECMO) compared with conventional invasive mechanical ventilation (IMV) remains unknown. OBJECTIVES: To estimate the effect of ECMO on 90-Day mortality vs IMV only Methods: Among 4,244 critically ill adult patients with COVID-19 included in a multicenter cohort study, we emulated a target trial comparing the treatment strategies of initiating ECMO vs. no ECMO within 7 days of IMV in patients with severe acute respiratory distress syndrome (PaO2/FiO2 <80 or PaCO2 ≥60 mmHg). We controlled for confounding using a multivariable Cox model based on predefined variables. MAIN RESULTS: 1,235 patients met the full eligibility criteria for the emulated trial, among whom 164 patients initiated ECMO. The ECMO strategy had a higher survival probability at Day-7 from the onset of eligibility criteria (87% vs 83%, risk difference: 4%, 95% CI 0;9%) which decreased during follow-up (survival at Day-90: 63% vs 65%, risk difference: -2%, 95% CI -10;5%). However, ECMO was associated with higher survival when performed in high-volume ECMO centers or in regions where a specific ECMO network organization was set up to handle high demand, and when initiated within the first 4 days of MV and in profoundly hypoxemic patients. CONCLUSIONS: In an emulated trial based on a nationwide COVID-19 cohort, we found differential survival over time of an ECMO compared with a no-ECMO strategy. However, ECMO was consistently associated with better outcomes when performed in high-volume centers and in regions with ECMO capacities specifically organized to handle high demand. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/)

    [Obra selecta]

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    Tít. de la portada : Para el caminoAnatole France es el seud. de Jackes Anatole ThibaultProbablemente imp. ca. 1901-1940Probablemente imp. entre 1900-1940Antep. con tít. : Para el caminoCada contiene con port. propiaContiene: Baltasar ; La reseda del cura ; El señor Pigeonneau ; La hija de Lilith ; Loeta Acilia ; El huevo rojo ; Abej

    Crainqueville ; Putois ; Riquet y otros ralatos edificantes

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    Título: O gato magro

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    Marca tipográfica del editor en la portadaMarca tip. do ed. na portPortada de serie antes de la anteportadaAntepPort. de serie antes da ante

    Le vovre de mon ami

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    237 tr. ; 19 cm

    Yocasta ; El gato flaco : novela

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    Anatole France es seud. de Jacques Anatole ThibaultJuan Pueyo ejerce como impresor ca. 1912-1936Contiene: Yocasta (1-153 p.) ; El gato flaco (155-283 p.
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