Morehshin Allahyari : Material Speculation

"MATERIAL SPECULATION presents radical propositions for 3D Printing that inspect petropolitical and poetic relationships between 3D Printing, Plastic, Oil, Terrorism, and Technocapitalism. Allahyari addresses complex contemporary cultural and political dynamics with the sophistication and nuance it deserves, weaving multiple dynamics together for a holistic image of contemporary relations with objecthood and ideology. " -- Publisher's website

The Public Health Response to COVID-19 in the Northeast Region of Missouri

The Public Health Response to COVID-19 in the Northeast Region of Missouri documents efforts by Northeast Missouri’s local public health agencies along with other stakeholders to leverage their partnerships, resources, and expertise to respond to COVID-19. Along with professional stakeholder accounts, the report includes residents’ perspectives and experiences during the COVID-19 response. Professional and resident findings helped identify lessons that could strengthen the public health system’s ability to continue responding to COVID-19 and face future crisis with greater resources, coordination, equitable strategies, modernized infrastructure and public trust. The findings in this report center on the period of the pandemic from March 2020 through May 2021, before the proliferation of the Delta and Omicron variants. The Public Health Response to COVID-19 in the Northeast Region of Missouri along with The Public Health Response to COVID-19 in the Southwest Region of Missouri and The Public Health Response to COVID-19 in the St. Louis Region of Missouri are part of a series of regional reports that were used to inform the state-level recommendations in the report Missouri’s Public Health Response to COVID-19: Key Findings and Recommendations for State Action and Investment

The Oldest Paleo-Sal Forest ? Reconstruction of Myanmar Eocene vegetation

International audienceLes formations géologiques mio-pliocènes de Birmanie ont livré de nombreux restes végétaux qui permettent aujourd’hui une bonne reconstitution de la diversité ligneuse de cette période. Bien qu’abondants les dépôts plus anciens n’ont pour l’instant fait l’objet que de peu d’études paléobotaniques. Depuis une dizaine d’années de très nombreux échantillons de bois fossiles ont pu être récoltés dans le cadre de plusieurs missions paléontologiques franco-birmanes. L’étude et la description d’une quarantaine de ces restes provenant de différents sites appartenant à la Formation Pondaung nous permettent aujourd’hui de proposer une reconstitution de l’environnement forestier pour l’Eocène moyen. Ainsi, les échantillons de bois fossile ont été rattachés à des familles botaniques modernes : Caesalpinaceae, Moraceae, Combretaceae, Sapindaceae, Malvaceae, Dipterocarpaceae, Theaceae et 5 nouvelles espèces ont pu être décrites. Les bois fossiles décrits ont été rapprochés d’espèces actuelles. Ces dernières composent aujourd’hui différents écotones des forêts de Sal Sud-Est asiatiques modernes, reflétant ainsi un climat probablement plus sec que ce qui avait été envisagé par le passé. En complément de cette approche floristique une étude statistique des caractères anatomiques du bois telle que proposée par Wiemann et al. (1998) nous permet de proposer une reconstitution de certains paramètres climatiques

The Oldest Paleo-Sal Forest ? Reconstruction of Myanmar Eocene vegetation

International audienceLes formations géologiques mio-pliocènes de Birmanie ont livré de nombreux restes végétaux qui permettent aujourd’hui une bonne reconstitution de la diversité ligneuse de cette période. Bien qu’abondants les dépôts plus anciens n’ont pour l’instant fait l’objet que de peu d’études paléobotaniques. Depuis une dizaine d’années de très nombreux échantillons de bois fossiles ont pu être récoltés dans le cadre de plusieurs missions paléontologiques franco-birmanes. L’étude et la description d’une quarantaine de ces restes provenant de différents sites appartenant à la Formation Pondaung nous permettent aujourd’hui de proposer une reconstitution de l’environnement forestier pour l’Eocène moyen. Ainsi, les échantillons de bois fossile ont été rattachés à des familles botaniques modernes : Caesalpinaceae, Moraceae, Combretaceae, Sapindaceae, Malvaceae, Dipterocarpaceae, Theaceae et 5 nouvelles espèces ont pu être décrites. Les bois fossiles décrits ont été rapprochés d’espèces actuelles. Ces dernières composent aujourd’hui différents écotones des forêts de Sal Sud-Est asiatiques modernes, reflétant ainsi un climat probablement plus sec que ce qui avait été envisagé par le passé. En complément de cette approche floristique une étude statistique des caractères anatomiques du bois telle que proposée par Wiemann et al. (1998) nous permet de proposer une reconstitution de certains paramètres climatiques

Bois fossile et mousson asiatique

International audienc

Bois fossile et mousson asiatique

International audienc

A Palladium-Catalyzed Oxa-(4+4)-Cycloaddition Strategy Towards Oxazocine Scaffolds

International audienceA Pd-catalyzed oxa-(4+4)-cycloaddition between 1-azadienes and (2-hydroxymethyl)allyl carbonates is described. Aurone-derived azadienes furnished polycyclic 1,5-oxazocines in good yields. Interestingly, linear azadienes have also been involved and yielded monocyclic heterocycles with complete regioselectivity. DFT calculations were carried out to gain insight on this observation

Naturally improving the natural cytotoxicity of natural killer (NK) cells

International audienceThe innate lymphocyte lineage natural killer (NK) is now the target of multiple clinical applications, although none has received an agreement from any regulatory agency yet. Transplant of naïve NK cells has not proven efficient enough in the vast majority of clinical trials. Hence, new protocols wish to improve their medical use by producing them from stem cells and/or modifying them by genetic engineering. These techniques have given interesting results but these improvements often hide that natural killers are mainly that: natural. We discuss here different ways to take advantage of NK physiology to improve their clinical activity without the need of additional modifications except for in vitro activation and expansion and allograft in patients. Some of these tactics include combination with monoclonal antibodies (mAb), drugs that change metabolism and engraftment of specific NK subsets with particular activity. Finally, we propose to use specific NK cell subsets found in certain patients that show increase activity against a specific disease, including the use of NK cells derived from patients

Naturally improving the natural cytotoxicity of natural killer (NK) cells

International audienceThe innate lymphocyte lineage natural killer (NK) is now the target of multiple clinical applications, although none has received an agreement from any regulatory agency yet. Transplant of naïve NK cells has not proven efficient enough in the vast majority of clinical trials. Hence, new protocols wish to improve their medical use by producing them from stem cells and/or modifying them by genetic engineering. These techniques have given interesting results but these improvements often hide that natural killers are mainly that: natural. We discuss here different ways to take advantage of NK physiology to improve their clinical activity without the need of additional modifications except for in vitro activation and expansion and allograft in patients. Some of these tactics include combination with monoclonal antibodies (mAb), drugs that change metabolism and engraftment of specific NK subsets with particular activity. Finally, we propose to use specific NK cell subsets found in certain patients that show increase activity against a specific disease, including the use of NK cells derived from patients