82 research outputs found
Morehshin Allahyari : Material Speculation
"MATERIAL SPECULATION presents radical propositions for 3D Printing that inspect petropolitical and poetic relationships between 3D Printing, Plastic, Oil, Terrorism, and Technocapitalism. Allahyari addresses complex contemporary cultural and political dynamics with the sophistication and nuance it deserves, weaving multiple dynamics together for a holistic image of contemporary relations with objecthood and ideology. " -- Publisher's website
The Public Health Response to COVID-19 in the Northeast Region of Missouri
The Public Health Response to COVID-19 in the Northeast Region of Missouri documents efforts by Northeast Missouriâs local public health agencies along with other stakeholders to leverage their partnerships, resources, and expertise to respond to COVID-19. Along with professional stakeholder accounts, the report includes residentsâ perspectives and experiences during the COVID-19 response. Professional and resident findings helped identify lessons that could strengthen the public health systemâs ability to continue responding to COVID-19 and face future crisis with greater resources, coordination, equitable strategies, modernized infrastructure and public trust. The findings in this report center on the period of the pandemic from March 2020 through May 2021, before the proliferation of the Delta and Omicron variants.
The Public Health Response to COVID-19 in the Northeast Region of Missouri along with The Public Health Response to COVID-19 in the Southwest Region of Missouri and The Public Health Response to COVID-19 in the St. Louis Region of Missouri are part of a series of regional reports that were used to inform the state-level recommendations in the report Missouriâs Public Health Response to COVID-19: Key Findings and Recommendations for State Action and Investment
The Oldest Paleo-Sal Forest ? Reconstruction of Myanmar Eocene vegetation
International audienceLes formations gĂ©ologiques mio-pliocĂšnes de Birmanie ont livrĂ© de nombreux restes vĂ©gĂ©taux qui permettent aujourdâhui une bonne reconstitution de la diversitĂ© ligneuse de cette pĂ©riode. Bien quâabondants les dĂ©pĂŽts plus anciens nâont pour lâinstant fait lâobjet que de peu dâĂ©tudes palĂ©obotaniques. Depuis une dizaine dâannĂ©es de trĂšs nombreux Ă©chantillons de bois fossiles ont pu ĂȘtre rĂ©coltĂ©s dans le cadre de plusieurs missions palĂ©ontologiques franco-birmanes. LâĂ©tude et la description dâune quarantaine de ces restes provenant de diffĂ©rents sites appartenant Ă la Formation Pondaung nous permettent aujourdâhui de proposer une reconstitution de lâenvironnement forestier pour lâEocĂšne moyen. Ainsi, les Ă©chantillons de bois fossile ont Ă©tĂ© rattachĂ©s Ă des familles botaniques modernes : Caesalpinaceae, Moraceae, Combretaceae, Sapindaceae, Malvaceae, Dipterocarpaceae, Theaceae et 5 nouvelles espĂšces ont pu ĂȘtre dĂ©crites. Les bois fossiles dĂ©crits ont Ă©tĂ© rapprochĂ©s dâespĂšces actuelles. Ces derniĂšres composent aujourdâhui diffĂ©rents Ă©cotones des forĂȘts de Sal Sud-Est asiatiques modernes, reflĂ©tant ainsi un climat probablement plus sec que ce qui avait Ă©tĂ© envisagĂ© par le passĂ©. En complĂ©ment de cette approche floristique une Ă©tude statistique des caractĂšres anatomiques du bois telle que proposĂ©e par Wiemann et al. (1998) nous permet de proposer une reconstitution de certains paramĂštres climatiques
The Oldest Paleo-Sal Forest ? Reconstruction of Myanmar Eocene vegetation
International audienceLes formations gĂ©ologiques mio-pliocĂšnes de Birmanie ont livrĂ© de nombreux restes vĂ©gĂ©taux qui permettent aujourdâhui une bonne reconstitution de la diversitĂ© ligneuse de cette pĂ©riode. Bien quâabondants les dĂ©pĂŽts plus anciens nâont pour lâinstant fait lâobjet que de peu dâĂ©tudes palĂ©obotaniques. Depuis une dizaine dâannĂ©es de trĂšs nombreux Ă©chantillons de bois fossiles ont pu ĂȘtre rĂ©coltĂ©s dans le cadre de plusieurs missions palĂ©ontologiques franco-birmanes. LâĂ©tude et la description dâune quarantaine de ces restes provenant de diffĂ©rents sites appartenant Ă la Formation Pondaung nous permettent aujourdâhui de proposer une reconstitution de lâenvironnement forestier pour lâEocĂšne moyen. Ainsi, les Ă©chantillons de bois fossile ont Ă©tĂ© rattachĂ©s Ă des familles botaniques modernes : Caesalpinaceae, Moraceae, Combretaceae, Sapindaceae, Malvaceae, Dipterocarpaceae, Theaceae et 5 nouvelles espĂšces ont pu ĂȘtre dĂ©crites. Les bois fossiles dĂ©crits ont Ă©tĂ© rapprochĂ©s dâespĂšces actuelles. Ces derniĂšres composent aujourdâhui diffĂ©rents Ă©cotones des forĂȘts de Sal Sud-Est asiatiques modernes, reflĂ©tant ainsi un climat probablement plus sec que ce qui avait Ă©tĂ© envisagĂ© par le passĂ©. En complĂ©ment de cette approche floristique une Ă©tude statistique des caractĂšres anatomiques du bois telle que proposĂ©e par Wiemann et al. (1998) nous permet de proposer une reconstitution de certains paramĂštres climatiques
A Palladium-Catalyzed Oxa-(4+4)-Cycloaddition Strategy Towards Oxazocine Scaffolds
International audienceA Pd-catalyzed oxa-(4+4)-cycloaddition between 1-azadienes and (2-hydroxymethyl)allyl carbonates is described. Aurone-derived azadienes furnished polycyclic 1,5-oxazocines in good yields. Interestingly, linear azadienes have also been involved and yielded monocyclic heterocycles with complete regioselectivity. DFT calculations were carried out to gain insight on this observation
Naturally improving the natural cytotoxicity of natural killer (NK) cells
International audienceThe innate lymphocyte lineage natural killer (NK) is now the target of multiple clinical applications, although none has received an agreement from any regulatory agency yet. Transplant of naĂŻve NK cells has not proven efficient enough in the vast majority of clinical trials. Hence, new protocols wish to improve their medical use by producing them from stem cells and/or modifying them by genetic engineering. These techniques have given interesting results but these improvements often hide that natural killers are mainly that: natural. We discuss here different ways to take advantage of NK physiology to improve their clinical activity without the need of additional modifications except for in vitro activation and expansion and allograft in patients. Some of these tactics include combination with monoclonal antibodies (mAb), drugs that change metabolism and engraftment of specific NK subsets with particular activity. Finally, we propose to use specific NK cell subsets found in certain patients that show increase activity against a specific disease, including the use of NK cells derived from patients
Naturally improving the natural cytotoxicity of natural killer (NK) cells
International audienceThe innate lymphocyte lineage natural killer (NK) is now the target of multiple clinical applications, although none has received an agreement from any regulatory agency yet. Transplant of naĂŻve NK cells has not proven efficient enough in the vast majority of clinical trials. Hence, new protocols wish to improve their medical use by producing them from stem cells and/or modifying them by genetic engineering. These techniques have given interesting results but these improvements often hide that natural killers are mainly that: natural. We discuss here different ways to take advantage of NK physiology to improve their clinical activity without the need of additional modifications except for in vitro activation and expansion and allograft in patients. Some of these tactics include combination with monoclonal antibodies (mAb), drugs that change metabolism and engraftment of specific NK subsets with particular activity. Finally, we propose to use specific NK cell subsets found in certain patients that show increase activity against a specific disease, including the use of NK cells derived from patients
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