Mujeres que inspiran…Grandes historias de guerreras

Recopilación de historias propias o contadas por terceros de mujeres que han superado retos, dificultades, competencias y cómo han conseguido lograr hazañas inspiradoras.Collection of own or told stories by third parties of women who have overcome challenges, difficulties, competencies and how they have managed to achieve inspiring feats.Yamel Rodríguez -- Iber James Quiñones -- Diana Yamileth Velasquez Maldonado -- Nidia Karina Mora Londoño -- Aura María Rosero -- Catherine Caicedo -- David Alejandro Mera Benavides -- Elizabeth Cárdenas Berrío -- Jhon Jairo Leal F. -- Miguel Ángel Solís -- Milton Cesar Mera Osorio -- Elizabeth González Londoño -- Lorena Villegas -- Ana María Cortés Rosero -- Jhonathan Paul Obando Vera -- María Elena Realpe Delgado -- Carolina Medina Alcalde -- Yaneth Ariasna34 página

The U.S.-Mexico Border Infectious Disease Surveillance Project: Establishing Binational Border Surveillance

In 1997, the Centers for Disease Control and Prevention, the Mexican Secretariat of Health, and border health officials began the development of the Border Infectious Disease Surveillance (BIDS) project, a surveillance system for infectious diseases along the U.S.-Mexico border. During a 3-year period, a binational team implemented an active, sentinel surveillance system for hepatitis and febrile exanthems at 13 clinical sites. The network developed surveillance protocols, trained nine surveillance coordinators, established serologic testing at four Mexican border laboratories, and created agreements for data sharing and notification of selected diseases and outbreaks. BIDS facilitated investigations of dengue fever in Texas-Tamaulipas and measles in California–Baja California. BIDS demonstrates that a binational effort with local, state, and federal participation can create a regional surveillance system that crosses an international border. Reducing administrative, infrastructure, and political barriers to cross-border public health collaboration will enhance the effectiveness of disease prevention projects such as BIDS

Estudio de ecosistemas terrestres y acuáticos ubicados en el parque nacional natural cueva de los guácharos (acevedo, huila)

Los estudios realizados durante el tiempo en el que se realizó la salida de campo de la asignatura Ecología Regional Continental del 3 al 17 de septiembre de 2010 permitieron determinar ciertas características y estados de calidad en los sistemas acuáticos y vegetales (bosque subandino) del Parque Nacional Natural Cueva de los Güácharos(PNNCG). Para el estudio limnológico se realizaron muestreos en varios ecosistemas acuáticos: Laguna Encantada, Quebrada Chánchiras, Quebrada La Lindosa, Cascada Cristales, Rí­o Suaza, Cueva de los Guacharos y Cueva del Indio. Se tomaron muestras a de variales fisicoquímicas y de comunidades biológicas (perifiton, plancton, macroinvertebrados). Las aguas de la región son de temperaturas medias y se mineralizan al pasar por el sistema de cuevas; son ligeramente alcalinas y bajas en nutrientes (oligotróficas) y transportan bajas a moderadas cantidades de sólidos suspendidos. Los datos fisicoquímicos que caracterizan a los ecosistemas acuáticos del PNNCG corresponden a sistemas típicos neotropicales, con baja intervención humana y condiciones propias de ambientes cársticos. La materia orgánica aportada por la vegetación riparia y por las macrófitas sustenta diferentes órdenes de macroinvertebrados, siendo los más representativos Diptera, Ephemeroptera, Hemíptera y Trichoptera. El bosque subandino estudiado se encuentra en proceso de desarrollo debido a que presenta una mayor cantidad de arboles del conjunto del futuro; no obstante, el conjunto del presente, aunque en una menor proporción, se encuentra bien establecido. Esto también se puede observar en los mapas de cobertura vegetal del estrato arbóreo, donde el dosel es continuo y solamente se interrumpe por los disturbios ocasionados por la muerte y caída de árboles del conjunto del presente, lo que genera claros en el bosque y permite que los arboles del conjunto del futuro desarrollen su cobertura

Differential clinical characteristics and prognosis of intraventricular conduction defects in patients with chronic heart failure

Intraventricular conduction defects (IVCDs) can impair prognosis of heart failure (HF), but their specific impact is not well established. This study aimed to analyse the clinical profile and outcomes of HF patients with LBBB, right bundle branch block (RBBB), left anterior fascicular block (LAFB), and no IVCDs. Clinical variables and outcomes after a median follow-up of 21 months were analysed in 1762 patients with chronic HF and LBBB (n = 532), RBBB (n = 134), LAFB (n = 154), and no IVCDs (n = 942). LBBB was associated with more marked LV dilation, depressed LVEF, and mitral valve regurgitation. Patients with RBBB presented overt signs of congestive HF and depressed right ventricular motion. The LAFB group presented intermediate clinical characteristics, and patients with no IVCDs were more often women with less enlarged left ventricles and less depressed LVEF. Death occurred in 332 patients (interannual mortality = 10.8%): cardiovascular in 257, extravascular in 61, and of unknown origin in 14 patients. Cardiac death occurred in 230 (pump failure in 171 and sudden death in 59). An adjusted Cox model showed higher risk of cardiac death and pump failure death in the LBBB and RBBB than in the LAFB and the no IVCD groups. LBBB and RBBB are associated with different clinical profiles and both are independent predictors of increased risk of cardiac death in patients with HF. A more favourable prognosis was observed in patients with LAFB and in those free of IVCDs. Further research in HF patients with RBBB is warranted

Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

Across multiancestry groups, we analyzed Human Leukocyte Antigen (HLA) associations in over 176,000 individuals with Parkinson’s disease (PD) and Alzheimer’s disease (AD) versus controls. We demonstrate that the two diseases share the same protective association at the HLA locus. HLA-specific fine-mapping showed that hierarchical protective effects of HLA-DRB1*04 subtypes best accounted for the association, strongest with HLA-DRB1*04:04 and HLA-DRB1*04:07, and intermediary with HLA-DRB1*04:01 and HLA-DRB1*04:03. The same signal was associated with decreased neurofibrillary tangles in postmortem brains and was associated with reduced tau levels in cerebrospinal fluid and to a lower extent with increased Aβ42. Protective HLA-DRB1*04 subtypes strongly bound the aggregation-prone tau PHF6 sequence, however only when acetylated at a lysine (K311), a common posttranslational modification central to tau aggregation. An HLA-DRB1*04-mediated adaptive immune response decreases PD and AD risks, potentially by acting against tau, offering the possibility of therapeutic avenues

Uso del aceite de neem (azadirachta indica a. juss) como alternativa agroecológica en el control de mastitis subclínica en bovinos en el municipio Acosta, estado Falcón

The research was carried out in the production unit Tacarigua, located in El Mene de San Lorenzo, Acosta municipality, Falcón State. The experimental design was completely randomized, with four treatments and four replications. The treatments were: neem oil 5%, neem oil 10%, neem oil 15% and control, Iodine solution. For analyzing the differences on the prevalence of subclinical mastitis, a proportion comparison test was conducted using the program SAS (2001). There were no significant differences among the neem oil treatments with the control treatment, demonstrating the potentiality of neem oil for the control of subclinical mastitis. as a substitute of chemical agents, aggressive to human health and the environment; which are tradicionally used as postmilking disinfectantsLa investigación se realizó en la unidad de producción Tacarigua, ubicada en El Mene de San Lorenzo, municipio Acosta, estado Falcón. El diseño experimental empleado fue completamente aleatorizado, con cuatro tratamientos y cinco réplicas, los tratamientos fueron: Aceite de neem al 5%, Aceite de neem al 10%, Aceite de neem al 15% y como tratamiento control, solución yodada. Para analizar las diferencias en las prevalencias de mastitis subclínicas, se utilizó la prueba de comparación de proporciones empleando el programa SAS (2001). Los resultados indican que no se presentaron diferencias significativas entre los tratamientos de neem y el tratamiento tradicional, la solución yodada, lo que demuestra el potencial del aceite de neem para el control de la mastitis subclínica como sustituto de agentes químicos agresivos a la salud del hombre y el ambiente en general, que son tradicionalmente usados comodesinfectantes postordeño

USE OF NEEM OIL (AZADIRACHTA INDICA A. JUSS) AS AGRO-ECOLOGICAL ALTERNATIVE IN THE CONTROL OF SUBCLINICAL MASTITIS IN CATTLE IN THE MUNICIPALITY ACOSTA, ESTADO FALCÓN

The research was carried out in the production unit Tacarigua, located in El Mene de San Lorenzo, Acosta municipality, Falcón State. The experimental design was completely randomized, with four treatments and four replications. The treatments were: neem oil 5%, neem oil 10%, neem oil 15% and control, Iodine solution. For analyzing the differences on the prevalence of subclinical mastitis, a proportion comparison test was conducted using the program SAS (2001). There were no significant differences among the neem oil treatments with the control treatment, demonstrating the potentiality of neem oil for the control of subclinical mastitis. as a substitute of chemical agents, aggressive to human health and the environment; which are tradicionally used as post milking disinfectant

Propuesta de un plan de mercadeo para la comercialización de árboles de Costa Rica en peligro de extinción para el vivero forestal El Guardián del Bosque

Seminario de graduación (licenciatura en dirección de empresas)UCR::Vicerrectoría de Docencia::Ciencias Sociales::Facultad de Ciencias Económicas::Escuela de Administración de Negocio