Multi-project scheduling with 2-stage decomposition

A non-preemptive, zero time lag multi-project scheduling problem with multiple modes and limited renewable and nonrenewable resources is considered. A 2-stage decomposition approach is adopted to formulate the problem as a hierarchy of 0-1 mathematical programming models. At stage one, each project is reduced to a macro-activity with macro-modes resulting in a single project network where the objective is the maximization of the net present value and the cash flows are positive. For setting the time horizon three different methods are developed and tested. A genetic algorithm approach is designed for this problem, which is also employed to generate a starting solution for the exact solution procedure. Using the starting times and the resource profiles obtained in stage one each project is scheduled at stage two for minimum makespan. The result of the first stage is subjected to a post-processing procedure to distribute the remaining resource capacities. Three new test problem sets are generated with 81, 84 and 27 problems each and three different configurations of solution procedures are tested

Multi-project scheduling with two-stage decomposition

We consider a non-preemptive, zero time lag multi-project scheduling problem with multiple modes and limited renewable and nonrenewable resources. A 2-stage decomposition approach is adopted to formulate the problem as a hierarchy of 0-1 mathematical programming models. In stage one; each project is reduced to a macro-activity with macro-modes. The macro-activities are combined into a single macro-activity network over which the macro-activity scheduling problem (MP) is defined, where the objective is the maximization of the net present value with positive cash flows and the renewable resource requirements are time-dependent. An exact solution procedure and a genetic algorithm (GA) approach are proposed for solving the MP. A GA is also employed to generate an initial solution for the exact solution procedure. The first stage terminates with a post-processing procedure to distribute the remaining resource capacities. Using the start times and the resource profiles obtained in stage one, each project is scheduled in stage two for minimum makespan. Three new test problem sets are generated with 81, 84 and 27 problems each, and three different configurations of solution procedures are tested

Recent Advances in Health Biotechnology During Pandemic

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in 2019, cut the epoch that will make profound fluctuates in the history of the world in social, economic, and scientific fields. Urgent needs in public health have brought with them innovative approaches, including diagnosis, prevention, and treatment. To exceed the coronavirus disease 2019 (COVID-19) pandemic, various scientific authorities in the world have procreated advances in real time polymerase chain reaction (RT-PCR) based diagnostic tests, rapid diagnostic kits, the development of vaccines for immunization, and the purposing pharmaceuticals for treatment. Diagnosis, treatment, and immunization approaches put for- ward by scientific communities are cross-fed from the accrued knowledge of multidisciplinary sciences in health biotechnology. So much so that the pandemic, urgently prioritized in the world, is not only viral infections but also has been the pulsion in the development of novel approaches in many fields such as diagnosis, treatment, translational medicine, virology, mi- crobiology, immunology, functional nano- and bio-materials, bioinformatics, molecular biol- ogy, genetics, tissue engineering, biomedical devices, and artificial intelligence technologies. In this review, the effects of the COVID-19 pandemic on the development of various scientific areas of health biotechnology are discussed

Investigation of thermal and hydraulic performance of evaporative cooler with thermoelectric cooling cabinet

Bu tez çalışması Pamukkale Üniversitesi Bilimsel Araştırma Projeleri tarafından 2018FEBE030 nolu proje ile desteklenmiştir.Artan enerji maliyetleri ve çevreye duyarlılık düşünüldüğünde, çevre dostu ve yüksek enerji verimliliğine sahip tasarımlar ve ürünler büyük önem kazanmıştır. Bu çalışmada, buharlaşmalı soğutma ve termoelektrik soğutma prensiplerini barındıran çevre dostu ürünün 3B tasarımı, ısıl ve hidrolik performanslarının incelenmesi gerçekleştirilmiştir. Sıcak yüzeyden ısının atılma mekanizmasına ve konumuna göre 3 farklı prototip elde edilmiş ve deneysel çalışmalar ASHRAE standartlarına uygun test odasında 38°C, %20 nem kondisyon değerlerinde gerçekleştirilmiştir. Yapılan deneysel çalışmalar neticesinde termoelektrik dolabın buharlaşmalı soğutucu çalışmasına olumsuz bir etkisi olmadığı gözlemlenmiştir. Deneyler sonucunda dolap içi sıcaklıkları su soğutmalı sistemde 5°C, hava soğutmalı sistemlerde ise sıcak kanatçık çevre ortamındayken 22°C, buharlaşmalı soğutucu içerisindeyken 17°C’ye kadar düşmüştür.Considering rising energy costs and environmental awareness, environmentally friendly and high energy efficient designs and products have gained great importance. In this study, environment-friendly 3D product design including evaporative cooling and thermoelectric cooling principles, investigation thermal and hydraulic performance has been achieved. In addition, 3 different prototypes were obtained according to the location and mechanism of heat rejection from the hot side and experimental studies were carried out in the test room in accordance with ASHRAE (American Society of Heating Refrigerating and Air Conditioning Engineers) standards at 38°C, %20 humidity. As a result of the experimental studies, it was observed that thermoelectric cabinet had no negative effect on evaporative cooler operation. As a result of the experiments, the in thermoelectric cabinet temperatures were reduced to 5°C in the water-cooled system. The thermoelectric cabinet temperature was measured at 22°C with hot heat sink in ambient conditions and 17°C with hot heat sink in evaporative cooler

Ömer Fevzi Atabek & eğitim yaşantısı

Ankara : İhsan Doğramacı Bilkent Üniversitesi İktisadi, İdari ve Sosyal Bilimler Fakültesi, Tarih Bölümü, 2014.This work is a student project of the The Department of History, Faculty of Economics, Administrative and Social Sciences, İhsan Doğramacı Bilkent University.by Ünsal, Mehmet Süha

Turkish validity and reliability of the Sexual Complaints Screener for Women

OBJECTIVE: The Sexual Complaints Screener for Women (SCS-W) is a brief, practical and up-to-date scale which assesses sexual problems parallel with the current diagnostic manuals. The SCS-W consists of 10 questions which assess a variety of sexual dysfunctions and potential distress experienced at the time of and the last six months leading to the evaluation. This study aims to assess the validity and reliability parameters of the Turkish version of the SCS-W. METHODS: Cross-sectional study included 352 women between the ages of 18 and 25 who voluntarily completed the survey, 316 of which were included in the analysis. Data was collected through specific questionnaires including the Female Sexual Function Index, the Short Form Health Survey (SF-36), the Turkish translation of SCS-W, and a sociodemographic form. The Cronbach Alpha Test was used to calculate the internal consistency and the Pearson Correlation Test was used for total score correlations as well as to determine cross-validity. An explanatory factor analysis was applied to identify the validity of the scale. RESULTS: The average age of participants in the study was 21.17 ± 1.87. The Cronbach alpha internal consistency coefficient of the scale was 0.895, and the correlation coefficient for most of the items was found to be higher than 0.50. Correlation analysis between the SCS-W and the FSFI total score and subscales were statistically significant. CONCLUSION: The SCS-W has credible psychometric values for validity and reliability to screen and evaluate sexual complaints. To sum up, the SCS-W is a practical assessment tool with the considerable advantages of delivering cost-effective evaluation of female sexual problems in clinical settings, research, and daily practice

Turkish validity and reliability of the sexual complaints screener for men

OBJECTIVE: To evaluate the validity and reliability parameters of the Turkish version of the Sexual Complaints Screener for Men (SCS-M) which is a promising brief measure to assess sexual problems in daily practice. METHODS: A cross-sectional study was conducted online. Data was collected through an online validated and content specific questionnaire via self-reporting. In total, 230 male participants between the ages of 18 and 25 submitted the questionnaire. SCS-M was translated into Turkish and applied with the International Index of Erectile Function, the Short Form Health Survey (SF-36). The p-value was evaluated statistically significant at p < 0.05. RESULTS: The average age of participants was 21.89 ± 2.08. The Cronbach alpha internal consistency coefficient of the scale was 0.818. Correlation analysis between SCS-M, IIEF and IIEF sub-scales were statistically significant. CONCLUSION: Turkish version of the SCS-M presented good psychometric parameters. SCS-M is a valid and reliable measure for the screening and evaluation of sexual complaints. It was additionally identified as a valuable contributor to the short measures in assessing male sexual problems in research and clinical practice