Great Expectations: New Organizational Models for Overworked Liaisons Based on the UNCG Libraries Liaison Collections Responsibilities Task Force

Liaisons (subject specialists) keep getting busier. Research instruction, embedding in classes, outreach, collection development, weeding, assessing teaching and collections, promoting scholarly communication issues, and creating online learning objects are all potentially part of what a liaison is expected to do nowadays. So we hope every liaison is very interested—and very good—at all those responsibilities. Is that realistic? And does a liaison have time for all those things? At University of North Caroline at Greensboro (UNCG), library administrators decided it is time to examine how liaisons are organized to manage all of these competing responsibilities. The library formed a Liaison Collection Responsibilities Task Force to benchmark how other libraries might be handling the complexities of liaison responsibilities in innovative ways and to recommend several possible new organizational models for the collection development and public services work of liaisons. Members of the task force will review their benchmark findings and invite the audience to provide their own examples. Then we will present our recommendations for new organization models. Some recommendations will reflect incremental changes; others will be radical. We will ask the audience for feedback on the recommendations and suggestions for other models

Wound care challenges in children and adults with spina bifida: An open-cohort study

Skin breakdown is a frequent concern for individuals with spina bifida. We explored wound incidence in patients with spina bifida and how it varies across a person\u27s life span and functional neurologic level. We examined the settings in which skin breakdown most commonly occurred, looking for evidence of chronic, non-healing wounds. We also sought to develop criteria to improve wound monitoring. We identified reported wound episodes in an open-cohort study over a 13-year period, examining the hospital and outpatient clinical records of spina bifida patients at Children\u27s National Medical Center (CNMC). Current age, age at wound presentation, sex, weight, functional neurologic level, wound location, setting in which the wound was acquired, the development of a chronic wound, and presence of a shunt were recorded. Of the 376 patients in our clinical population, 123 (average age: 18.8 years, range: infancy–56 years) developed a total of 375 wounds; the majority of patients who developed one wound went on to develop one or more additional wounds, and 20 patients developed chronic wounds. Our data suggest that age bracket (adolescents), wheelchair use, and bare feet, as well as possibly obesity and reduced executive functioning, are key risk factors for wound development. These findings have led to a focused effort to increase wound education and prevention. In addition we report on our early experience using a wound care specialist to champion this initiative

Вивчення кварк-глюонної плазми хіггсового механізму порушення електрослабкої симетрії

Вже багато років наукове оточення всього світу хвилює питання звідки бере свій початок стандартна теорія походження матерії

Testing Longitudinal Relationships Between Binge Drinking, Marijuana Use, and Depressive Symptoms and Moderation by Sex

Both substance use and depression are common in adolescence and often comorbid. Past research has produced conflicting results on whether there is a temporal relationship and if so, in which direction it operates and how it may vary by sex. We examined the longitudinal associations between substance use frequency and depressive symptoms from adolescence into young adulthood, and whether the associations were moderated by sex

(1-Bromo­naphthalen-2-yl)acetonitrile

The title compound, C12H8BrN, was prepared as a starting material for a Suzuki cross-coupling reaction with a pinacol ester. The torsion angle about the ring–methylene C—C bond is 30.7 (3)°, such that the N atom is displaced by 1.174 (4) Å from the plane of the naphthalene ring system

Brief of Intellectual Property Law Scholars As Amici Curiae in Support of Neither Party, WesternGeco LLC v. Ion Geophysical Corp., No. 16-1011, US Supreme Court

This amici curiae brief was filed on behalf of Intellectual Property Law Scholars in WesternGeco LLC v. Ion Geophysical Corp. in the U.S. Supreme Court. The question presented is: Whether the U.S. Court of Appeals for the Federal Circuit erred in holding that lost profits arising from prohibited combinations occurring outside of the United States are categorically unavailable in cases in which patent infringement is proven under 35 U.S.C. § 271(f). In RJR Nabisco, Inc. v. European Community, 136 S. Ct. 2090 (2016), the Supreme Court articulated a two-step method for assessing the extraterritorial reach of a US statute: 1. A court should determine whether the presumption against extraterritoriality has been rebutted—that is, whether the statute gives a clear, affirmative indication that it applies extraterritorially. If the presumption is rebutted, the statute may have extraterritorial reach. 2. But even if the presumption has not been rebutted, a court should look at the focus of the statute. If the conduct relevant to the statute\u27s focus occurred in the United States, then the case involves a permissible domestic application even if other conduct occurred abroad; but if the conduct relevant to the focus occurred in a foreign country, then the case involves an impermissible extraterritorial application regardless of any other conduct that occurred in U.S. territory. The brief of amici curiae makes the follow points: 1. The Supreme Court has not squarely answered the question as to whether the presumption against extraterritoriality applies separately to remedial provisions of a statute generally (here whether it applies to § 284). We argue it does. 2. We argue that the territorial reach § 284 necessarily depends the relevant provision of § 271 used to find liability. Here, under § 271(f), the presumption is rebutted (though it would not be generally for a case under § 271(a), with NTP v. Research in Motion may be a counter-example when one looks at the focus at step 2)). 3. We also argue that the Court should offer more guidance as to what happens even if the RJR test is satisfied. RJR Nabisco seems to operate in binary fashion -- either the statute has extraterritorial reach or it doesn\u27t. But Microsoft Corp. v. AT&T Corp., and earlier Supreme Court decision also interpreting 35 U.S.C. § 271(f), suggests that the presumption may still have a role in interpreting a statute. We offer two suggestions on how the presumption should operate in this context. First, courts should seriously and formally consider issues of comity and potential conflicts with foreign law in assessing whether to apply U.S. law extraterritorially. Second, that territoriality should remain relevant in assessments of proximate cause

More than skin deep: Functional genomic basis for resistance to Amphibian Chytridiomycosis

The amphibian-killing chytrid fungus Batrachochytriumdendrobatidis (Bd) is one of themost generalist pathogens known, capable of infecting hundreds of species globally and causing widespread population declines and extinctions. However, some host species are seemingly unaffected by Bd, tolerating or clearing infections without clinical signs of disease. Variation in host immune responses is commonly evoked for these resistant or tolerant species, yet to date,we have nodirect comparisonof amphibian species responses to infection at the level of gene expression. In this study,we challenged four CentralAmerican frog species that vary in Bd susceptibility, with a sympatric virulent strain of the pathogen. We compared skin and spleen orthologous gene expression using differential expression tests and coexpression gene network analyses.Wefound that resistant species have reduced skin inflammatory responses andincreased expressionofgenes involved inskin integrity. Incontrast, onlyhighly susceptible species exhibited suppressionof splenic T-cell genes. We conclude that resistance to chytridiomycosis may be related to a species’ ability to escape the immunosuppressive activity of the fungus. Moreover, our results indicate that within-species differences in splenic proteolytic enzyme gene expression may contribute to intraspecific variation in survival. This first comparison of amphibian functional immunogenomic architecture in response to Bd provides insights into key genetic mechanisms underlying variation in disease outcomes among amphibian species

Decreasing body size is associated with reduced calving probability in critically endangered North Atlantic right whales

Funding: This work was supported by the Office of Naval Research (grant nos. N000142012697 and N000142112096) and the Strategic Environmental Research and Development Program (grant nos. RC20-1097, RC20-7188 and RC21-3091). Photogrammetry was supported by NOAA grant no. NA14OAR4320158 to Woods Hole Oceanographic Institution, and by NOAA's Southwest Fisheries Science Center.Body size is key to many life-history processes, including reproduction. Across species, climate change and other stressors have caused reductions in the body size to which animals can grow, called asymptotic size, with consequences for demography. A reduction in mean asymptotic length was documented for critically endangered North Atlantic right whales, in parallel with declines in health and vital rates resulting from human activities and environmental changes. Here, we tested whether smaller body size was associated with lower reproductive output, using a state-space model for individual health, survival and reproduction that quantifies the mechanistic links between these processes. Body size (as represented by the cube of length) was strongly associated with a female's calving probability at each reproductive opportunity. This relationship explained 62% of the variation in calving among reproductive females, along with their decreasing health (20%). The effects of decreasing mean body size on reproductive performance are another concerning indication of the worsening prospects for this species and many others affected by environmental change, requiring a focus of conservation and management interventions on improving conditions that affect reproduction as well as reducing mortality.Peer reviewe

International observational atopic dermatitis cohort to follow natural history and treatment course: TARGET-DERM AD study design and rationale

INTRODUCTION: As new topical and systemic treatments become available for atopic dermatitis (AD), there is a need to understand how treatments are being used in routine clinical practice, their comparative effectiveness and their long-term safety in diverse clinical settings. METHODS AND ANALYSIS: The TARGET-DERM AD cohort is a longitudinal, observational study of patients with AD of all ages, designed to provide practical information on long-term effectiveness and safety unobtainable in traditional registration trials. Patients with physician-diagnosed AD receiving prescription treatment (topical or systemic) will be enrolled at academic and community clinical centres. Up to 3 years of retrospective medical records, 5 years of prospective medical records, and optional biological samples and patient-reported outcomes will be collected. The primary aims include characterisation of AD treatment regimens, evaluation of response to therapy, and description of adverse events. ETHICS AND DISSEMINATION: TARGET-DERM has been approved by a central IRB (Copernicus Group IRB, 5000 Centregreen Way Suite 200, Cary, North Carolina 27513) as well as local and institutional IRBs. No additional Ethics Committee reviews. Results will be reviewed by a publications committee and submitted to peer-reviewed journals. TRIAL REGISTRATION NUMBER: NCT03661866, pre-results

The Mysticism Scale as Measure for Subjective Spirituality: New Results with Hood's M-Scale and the Development of a Short Form

Streib H, Klein C, Keller B, Hood RW. The Mysticism Scale as Measure for Subjective Spirituality: New Results with Hood's M-Scale and the Development of a Short Form. In: Ai AL, Harris KA, Wink P, Paloutzian R, eds. Assessing Spirituality and Religion in a Diversified World: Beyond the Mainstream Perspective. New York: Springer; 2021: 45.In this chapter, we suggest the use of Hood’s Mysticism Scale (M-scale) for a differential assessment of subjective spirituality. We base this view on the conceptualization of mysticism and its relation to spirituality, and on the definition of spirituality as individualized experience-orientated religiosity. This perspective was empirically tested in the Bielefeld-based Cross-cultural Study on Spirituality, which explored in comprehensive semantic analyses how participants in the USA and Germany define spirituality and revealed that more spiritual than religious people preferably associate spirituality with experiences of all-connectedness, search for a higher self, existential truth, and humanistic morality. Moreover, structural equations modeling based on this and other recent data sets reveal that the M-scale and its factors have considerable effects on self-rated spirituality. Thus, we recommend the M-scale as measure for subjective spirituality, which avoids the widespread problem of many extant measures that assess spirituality primarily in terms of either (Christian) religiosity or psychosocial well-being. The M-scale may be very useful in research that intends to assess the subjective spirituality of a diversity of participants who might affiliate with various religious traditions and worldviews, including the non-religious, atheists, and non-theists. Besides the well-established 32-item version of the M-scale, the chapter additionally presents an economic 8-item short form of the M-scale and its psychometric properties