On the evolution of the entropy and pressure profiles in X-ray luminous galaxy clusters at z > 0.4

Galaxy clusters are the most recent products of hierarchical accretion over cosmological scales. The gas accreted from the cosmic field is thermalized inside the cluster halo. Gas entropy and pressure are expected to have a self-similar behaviour with their radial distribution following a power law and a generalized Navarro-Frenk-White profile, respectively. This has been shown also in many different hydrodynamical simulations. We derive the spatially-resolved thermodynamical properties of 47 X-ray galaxy clusters observed with Chandra in the redshift range 0.4 < z < 1.2, the largest sample investigated so far in this redshift range with X-rays spectroscopy, with a particular care in reconstructing the gas entropy and pressure radial profiles. We search for deviation from the self-similar behaviour and look for possible evolution with redshift. The entropy and pressure profiles lie very close to the baseline prediction from gravitational structure formation. We show that these profiles deviate from the baseline prediction as function of redshift, in particular at z > 0.75, where, in the central regions, we observe higher values of the entropy (by a factor of 2.2) and systematically lower estimates (by a factor of 2.5) of the pressure. The effective polytropic index, which retains informations about the thermal distribution of the gas, shows a slight linear positive evolution with the redshift and the concentration of the dark matter distribution. A prevalence of non-cool-core, disturbed systems, as we observe at higher redshifts, can explain such behaviours.Comment: 14 pages, 18 figures, accepted for publication by A&

Stylish UV-C lamp for disinfecting household objects

In this study, UV-C device proved to be a valuable tool for disinfecting household items and enhancing safety for everyday healt

Contributions of implicit memory strategies to the rehabilitation of an amnesic patient: case report

Even severe amnesic patients usually are able to learn new information using implicit memory strategies. In the present study we describe our experience in the rehabilitation of an amnesic patient who had suffered cerebral anoxia. He was taught to use a computer text editor, enabling him to sheltered work. The training program lasted 14 weeks and was based on errorless learning and drilling practice techniques. The patient succeeded in all tasks, even though he could not remember accurately the training sessions. These results meet previous studies which point out that interaction between implicit and residual explicit memory can provide a basis new learning in amnesic patients. The domain-specific knowledge acquisition is demonstrating effectiveness in neuropsychological rehabilitation of brain injured patients.Mesmo pacientes severamente amnésticos são capazes de aprender informações novas, apoiados em estratégias de memória implícita. No presente estudo descrevemos uma experiência de reabilitação neuropsicológica, em que um paciente amnéstico, portador de lesão cerebral por anóxia, foi submetido a treino para uso de computador, visando sua capacitação semi-profissional. O treinamento teve duração de 14 semanas, e as técnicas de ensino utilizadas foram a prática repetitiva e a aprendizagem sem erros. O paciente obteve sucesso na realização das tarefas propostas, aprendendo a operar um editor de textos e mantendo o aprendizado após a passagem do tempo. Apesar disso, lembrava-se apenas vagamente da situação de aprendizagem. O presente estudo corrobora trabalhos anteriores que observam a interação entre mecanismos de memória implícita e resíduos de memória explícita operando na aquisição de conhecimentos em pacientes amnésticos. A aprendizagem de conhecimentos específicos vem se mostrando eficiente para a reabilitação de pacientes que sofreram lesões cerebrais.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de PsicobiologiaUNIFESP, EPM, Depto. de PsicobiologiaSciEL

Safer school with near-UV technology: novel applications for environmental hygiene

Systems capable of disinfecting air and surfaces could reduce the risk of infectious diseases transmission. Aim: to evalu-ate the effectiveness of near-UV LED ceiling lamps, with a wavelength of 405 nm, in improving environmental hygiene. Between November and December 2020, we conducted an experimental study having a pre-post design in a kindergarten room in Siena where 4 ceiling lamps with 405 nm LED technology were installed. Twice per day, sampling was performed before (T0) and after treatment with near-UV (T1). We used between 8 and 12 pairs of contact plates to sample at various random spots each day. Air samplings were also performed. The plates were incubated at 22 and 36 degrees C. Significance was set at 95% (p &lt; 0.05). The mean level of Colony Forming Unit (CFU) at T(0) was 249 (95% CI 193.1 - 305.0) at 36 degrees C and 535.2 (374.3 - 696.1) at 22 degrees C. The reduction was significant at T(1): by 65% at 36 degrees C and, 72% at 22 degrees C. Also, for air contamination: 95.3% (98.4 &amp; mdash;92.3). A dose threshold of about 5 J/cm2 was identified to have an 80% CFU abatement and remains nearly constant. The advantage of being able to use this technology in the presence of people is very important in the context of controlling environmental contamination. © 2023, The Author(s)

Combined inguinal hernia in the elderly. Portraying the progression of hernia disease

Introduction: Identification of a combined hernia is a common occurrence in the course of inguinal hernia repair. This type of protrusion disease seems to affect the elderly, in particular. Very few investigations have been carried out to ascertain the structural changes that occur in the groin affected by this clinical condition. Method: Analysis of intraoperative findings of combined inguinal hernias evidenced in the elderly, from the most recent 100 groin hernia repair procedures carried out by a single operator, represents the basis of the article. Protrusions that presumably represent the forerunner of this type of hernia were also analyzed: double ipsilateral inguinal hernias composed of a direct and an indirect protrusion. The gross anatomical, as well as histological, modifications occurring during the development of combined protrusions were also evaluated. Results: Combined hernia was the most frequent protrusion in patients over 65 years, accounting for 36% of the total in this patient group. In the same patient cohort, double inguinal hernia further involves 22% of elderly subjects. Macroscopically, progressive disruption of the inguinal back wall and degenerative reabsorption of the inferior epigastric vessels were evidenced. Histologically, inflammatory infiltrate, significant nerve and vascular injuries, along with severe muscle degeneration were recognized. Conclusions: The results seem to confirm that inguinal hernia is an unremitting progressive disease caused by chronic compressive structural damage. Combined hernias represent a frequent clinical condition in the elderly consequent to long-term degenerative damage. Therapy of combined protrusions must consider the impact of visceral vector forces

Intermittent dislocation flow in viscoplastic deformation

The viscoplastic deformation (creep) of crystalline materials under constant stress involves the motion of a large number of interacting dislocations. Analytical methods and sophisticated `dislocation-dynamics' simulations have proved very effective in the study of dislocation patterning, and have led to macroscopic constitutive laws of plastic deformation. Yet, a statistical analysis of the dynamics of an assembly of interacting dislocations has not hitherto been performed. Here we report acoustic emission measurements on stressed ice single crystals, the results of which indicate that dislocations move in a scale-free intermittent fashion. This result is confirmed by numerical simulations of a model of interacting dislocations that successfully reproduces the main features of the experiment. We find that dislocations generate a slowly evolving configuration landscape which coexists with rapid collective rearrangements. These rearrangements involve a comparatively small fraction of the dislocations and lead to an intermittent behavior of the net plastic response. This basic dynamical picture appears to be a generic feature in the deformation of many other materials. Moreover, it should provide a framework for discussing fundamental aspects of plasticity, that goes beyond standard mean-field approaches that see plastic deformation as a smooth laminar flow

Internalized Transphobia, Resilience, and Mental Health: Applying the Psychological Mediation Framework to Italian Transgender Individuals

Transgender and gender nonconforming (TGNC) people are a highly-stigmatized population. For this reason, they might internalize society’s normative gender attitudes and develop negative mental health outcomes. As an extension of the minority stress model, the psychological mediation framework sheds light on psychological processes through which anti-transgender discrimination might affect mental health. Within this framework, the current study aimed at assessing in 149 TGNC Italian individuals the role of internalized transphobia as a mediator between anti-transgender discrimination and mental health, considering resilience as the individual-level coping mechanism buffering this relationship. The results suggest that both indicators of internalized transphobia (i.e., shame and alienation) mediate the relationship between anti-transgender discrimination and depression, while only alienation mediates the relationship between anti-transgender discrimination and anxiety. Furthermore, the results suggest that the indirect relation between anti-transgender discrimination and anxiety through alienation is conditional on low and moderate levels of resilience. Findings have important implications for clinical practice and psycho-social interventions to reduce stigma and stress caused by interpersonal and individual stigma

Transannular patching is a valid alternative for tetralogy of Fallot and complete atrioventricular septal defect repair

Objective: We report our experience with repair of tetralogy of Fallot associated with complete atrioventricular septal defect, addressing in particular the need for a pulmonary valve in the right ventricular outflow tract. Methods: Between 1992 and 2006, 33 children with tetralogy of Fallot and complete atrioventricular septal defect were admitted; 26 had Down’s syndrome (79%). Thirty-two children had complete repair (18 primary, 14 staged); of the 15 who received initial palliation, 1 died before complete repair. Right ventricular outflow tract obstruction was relieved by transannular patch in 14 cases (42%), infundibular patch with preservation of the pulmonary valve in 7 (21%), and right ventricle–to–pulmonary artery conduit in 11 (33%). Results: There were no hospital deaths. Actuarial survival was 96% 3.9% at 5 years and 85.9 1.1% at 10 years. Multivariate analysis showed that type of relief of right ventricular outflow tract obstruction did not influence survival (P ¼ .16), nor did the choice to use a valved conduit (P ¼ .82). Primary correction (P ¼ .05) and lower weight at repair (P ¼ .05) were associated with higher probability of survival. Mean follow-up was 69.3 5.9 months (range 0.2–282 months). There were 2 late deaths. Overall freedom from reoperation was 69% at 5 years and 38%at 10 years. Right ventricular outflow tract reconstruction without use of a valved conduit allowed a significantly higher freedom from reinterventions (P<.05). Conclusions: Tetralogy of Fallot associated with complete atrioventricular septal defect can be corrected at low risk with favorable intermediate survival. Use of right ventricle–to–pulmonary artery conduit can be avoided in two thirds of patients with no impact on survival, possibly improving overall freedom from reintervention

Transannular patching is a valid alternative for tetralogy of Fallot and complete atrioventricular septal defect repair

Objective: We report our experience with repair of tetralogy of Fallot associated with complete atrioventricular septal defect, addressing in particular the need for a pulmonary valve in the right ventricular outflow tract. Methods: Between 1992 and 2006, 33 children with tetralogy of Fallot and complete atrioventricular septal defect were admitted; 26 had Down’s syndrome (79%). Thirty-two children had complete repair (18 primary, 14 staged); of the 15 who received initial palliation, 1 died before complete repair. Right ventricular outflow tract obstruction was relieved by transannular patch in 14 cases (42%), infundibular patch with preservation of the pulmonary valve in 7 (21%), and right ventricle–to–pulmonary artery conduit in 11 (33%). Results: There were no hospital deaths. Actuarial survival was 96% 3.9% at 5 years and 85.9 1.1% at 10 years. Multivariate analysis showed that type of relief of right ventricular outflow tract obstruction did not influence survival (P ¼ .16), nor did the choice to use a valved conduit (P ¼ .82). Primary correction (P ¼ .05) and lower weight at repair (P ¼ .05) were associated with higher probability of survival. Mean follow-up was 69.3 5.9 months (range 0.2–282 months). There were 2 late deaths. Overall freedom from reoperation was 69% at 5 years and 38%at 10 years. Right ventricular outflow tract reconstruction without use of a valved conduit allowed a significantly higher freedom from reinterventions (P<.05). Conclusions: Tetralogy of Fallot associated with complete atrioventricular septal defect can be corrected at low risk with favorable intermediate survival. Use of right ventricle–to–pulmonary artery conduit can be avoided in two thirds of patients with no impact on survival, possibly improving overall freedom from reintervention

Online sexual activities in Italian older adults: The role of gender, sexual orientation, and permissiveness

Introduction Online sexual activities (OSAs) are sexual behaviors involving online sexual content and stimuli and are categorized into non-arousal (N-OSAs), solitary arousal (S-OSAs), and partnered arousal activities (P-OSAs). As such activities in older age remain largely underexamined, this study aimed to explore OSAs in a sample of Italian older adults, analyzing their associations with gender and sexual orientation, considering sexual permissiveness as a moderator. Methods One hundred and fourteen cisgender participants (85 men and 29 women) aged from 52 to 79 years old (M = 62.57, SD = 6.19) were recruited between September 2019 and January 2020 to participate in an online cross-sectional survey on OSAs. Results A total of 58.1% of participants had engaged in S-OSAs at least 2–3 times during the previous month, while a lower percentage of participants had engaged in N-OSAs (38.6%) and P-OSAs (29.9%) at least 2–3 times during the previous month. Men were more likely to be engaged in S-OSAs than women. Being non-heterosexual was associated with an increase in engagement in N-OSAs and S-OSAs, but not in P-OSAs. Sexual permissiveness was significantly associated with N-OSAs and S-OSAs, but not with P-OSAs, and did not moderate either the relationship of gender with OSAs or that of sexual orientation with OSAs. Conclusions This study sheds light on the need to include online resources in sexual health educational programs addressed at older people, as well as in training programs addressed at healthcare professionals and social workers working with this population