2,594 research outputs found

    Behavior of cell aggregates under force-controlled compression

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    In this paper we study the mechanical behavior of multicellular aggregates under compressive loads and subsequent releases. Some analytical properties of the solution are discussed and numerical results are presented for a compressive test under constant force imposed on a cylindrical specimen. The case of a cycle of compressions at constant force and releases is also considered. We show that a steady state configuration able to bear the load is achieved. The analytical determination of the steady state value allows to obtain mechanical parameters of the cellular structure that are not estimable from creep tests at constant stres

    The dynamics of grouping-induced biases in apparent numerosity revealed by a continuous tracking technique

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    Connecting pairs of items causes robust underestimation of the numerosity of an ensemble, presumably by invoking grouping mechanisms. Here we asked whether this underestimation in numerosity judgments could be revealed and further explored by continuous tracking, a newly developed technique that allows for fast and efficient data acquisition and monitors the dynamics of the responses. Participants continuously reproduced the perceived numerosity of a cloud of dots by moving a cursor along a number line, while the number of dots and the proportion connected by lines varied over time following two independent random walks. The technique was robust and efficient, and correlated well with results obtained with a standard psychophysics task. Connecting objects with lines caused an underestimation of approximately 15% during tracking, agreeing with previous studies. The response to the lines was slower than the response to the physical numerosity, with a delay of approximately 150 ms, suggesting that this extra time is necessary for processing the grouping effect

    MOS CCDs for the wide field imager on the XEUS spacecraft

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    In recent years the XEUS mission concept has evolved and has been the subject of several industrial studies. The mission concept has now matured to the point that it could be proposed for a Phase A study and subsequent flight programme. The key feature of XEUS will be its X-ray optic with collecting area ~30-100x that of XMM. The mission is envisaged at an orbit around the L2 point in space, and is formed from two spacecraft; one for the mirrors, and the other for the focal plane detectors. With a focal length of 50m, the plate scale of the optic is 6.5x that of XMM, which using existing focal plane technology will reduce the effective field of view to a few arc minutes. Cryogenic instrumentation, with detector sizes of a few mm can only be used for narrow field studies of target objects, and a wide field instrument is under consideration using a DEPFET pixel array to image out to a diameter of 5 arcminutes, requiring an array of dimension 70mm. It is envisaged to extend this field of view possibly out to 15 arcminutes through the use of an outer detection ring comprised of MOS CCD

    Ideal observer analysis for continuous tracking experiments

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    Continuous tracking is a newly developed technique that allows fast and efficient data acquisition by asking participants to “track” a stimulus varying in some property (usually position in space). Tracking is a promising paradigm for the investigation of dynamic features of perception and could be particularly well suited for testing ecologically relevant situations difficult to study with classical psychophysical paradigms. The high rate of data collection may be useful in studies on clinical populations and children, who are unable to undergo long testing sessions. In this study, we designed tracking experiments with two novel stimulus features, numerosity and size, proving the feasibility of the technique outside standard object tracking. We went on to develop an ideal observer model that characterizes the results in terms of efficiency of conversion of stimulus strength into responses, and identification of early and late noise sources. Our ideal observer closely modeled results from human participants, providing a generalized framework for the interpretation of tracking data. The proposed model allows to use the tracking paradigm in various perceptual domains, and to study the divergence of human participants from ideal behavior

    Parents on the Same Page:A Mixed-Methods Investigation of the Acceptability and Appropriateness of Tuning in to Kids Together

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    In this study, we examined the acceptability and appropriateness of Tuning in to Kids Together (TIK-Together) from the perspective of program facilitators. TIK-Together is newly a modified version of Tuning in to Kids that specifically focuses on the coparenting relationship (i.e., how parents work together to raise their children) and requires parents to both attend sessions. Through a mixed-method design, Australian facilitators who participated in the TIK-Together pilot study provided their perspectives on the acceptability (i.e., affective attitudes, burden, program benefits) and appropriateness of the program in their communities. It is essential to involve stakeholders, such as program facilitators, in pilot studies as they can provide valuable feedback from their first-hand experience with the program. Facilitators reported that TIK-Together was enjoyable and rewarding, and although delivery was straightforward, additional preparation time was required to manage program materials. Facilitators observed several program benefits, including coparents becoming more aligned and collaborative in their approach to parenting. Certain program components were particularly helpful for parents, including activities that were experiential, interactive, and reflective. Overall, facilitators deemed TIK-Together appropriate for their communities; however, it is not suitable for parents who are uncomfortable or unwilling to work alongside each other in sessions. Given the increased focus on a coparent approach to parenting interventions, the findings provide important insights for researchers and practitioners.</p

    Numerical analysis of deep-seated mass movements in the Magura Nappe; Flysch Belt of the Western Carpathians (Czech Republic)

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    Deep-seated slope failures are common features in the mountains of the Raca Unit, Magura Nappe of the Flysch Belt of Western Carpathians. Since they represent very complicated system, understanding of their evolution and triggers still remains unclear. We tried to provide a back-analysis of their development by using a finite difference code (FDM) of continua (Flac 4.0). We confirmed that such large mass movements could be triggered by water saturation of the bedrock in the three particular geological and geomorphic settings. Such situation could have been caused by heavy rainfalls in humid phases of the Holocene or permafrost melting in Late Glacial. The effects of faulting, very deep weathering of the bedrock, low geotechnical parameters of smectite-rich material and the local slope geometry have also been accounted for in numerical models, as well as the other triggering factors of slope instability. FDM modelled shear zones are in agreement with observations

    Silicon photomultiplier arrays - a novel photon detector for a high resolution tracker produced at FBK-irst, Italy

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    A silicon photomultiplier (SiPM) array has been developed at FBK-irst having 32 channels and a dimension of 8.0 x 1.1 mm^2. Each 250 um wide channel is subdivided into 5 x 22 rectangularly arranged pixels. These sensors are developed to read out a modular high resolution scintillating fiber tracker. Key properties like breakdown voltage, gain and photon detection efficiency (PDE) are found to be homogeneous over all 32 channels of an SiPM array. This could make scintillating fiber trackers with SiPM array readout a promising alternative to available tracker technologies, if noise properties and the PDE are improved

    SiPM and front-end electronics development for Cherenkov light detection

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    The Italian Institute of Nuclear Physics (INFN) is involved in the development of a demonstrator for a SiPM-based camera for the Cherenkov Telescope Array (CTA) experiment, with a pixel size of 6Ă—\times6 mm2^2. The camera houses about two thousands electronics channels and is both light and compact. In this framework, a R&D program for the development of SiPMs suitable for Cherenkov light detection (so called NUV SiPMs) is ongoing. Different photosensors have been produced at Fondazione Bruno Kessler (FBK), with different micro-cell dimensions and fill factors, in different geometrical arrangements. At the same time, INFN is developing front-end electronics based on the waveform sampling technique optimized for the new NUV SiPM. Measurements on 1Ă—\times1 mm2^2, 3Ă—\times3 mm2^2, and 6Ă—\times6 mm2^2 NUV SiPMs coupled to the front-end electronics are presentedComment: In Proceedings of the 34th International Cosmic Ray Conference (ICRC2015), The Hague, The Netherlands. All CTA contributions at arXiv:1508.0589
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