50 research outputs found

    On the Castelnuovo-Mumford regularity of ideals, in dimension 2

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    We give a bound on the Castelnuovo-Mumford regularity of a homogeneous ideals I, in a polynomial ring A, in terms of number of variables and the degrees of generators, when the dimension of A/I is at most two. This bound improves the one obtained by Caviglia and Sbarra in this case. In the continuation of the examples constructed by Clare D'Cruz and the first author, we use families of monomial curves to construct homogeneous ideals showing that these bounds are quite sharp.Comment: 5 page

    Deployment of the Institut Pasteur de Dakar team to Guinea in the Ebola virus Disease outbreak in West-Africa 2014-2016

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    First paragraph: The unit of Arbovirus and Haemorrhagic Fever Viruses at the Institut Pasteur de Dakar (IPD), a WHO-approved collaborating Centre was the first laboratory deployed to Conakry in the Ebola virus disease (EVD) outbreak in West-Africa. On 20 March 2014, the IPD laboratory received a letter from the WHO and the Guinean Ministry of Health, informing about a suspected haemorrhagic fever outbreak and difficulties to send collected samples to IPD. They therefore requested the deployment of experts to Guinea for technical support in order to diagnose the haemorrhagic fever of unknown origin. The outbreak was identified by the Institut Pasteur (France) on 21 March 2014 [1,2] in samples shipped to France by a Médecins sans Frontières investigation team

    Evaluation De La Denutrition Chez Les Enfants Ages De 2 A 60 Mois Hospitalises Aux Services De Pediatrie Des Hopitaux De Ziguinchor (Senegal)

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    Introduction: Malnutrition is a public health problem in developing countries. The prevalence of malnutrition at the national level hardly reflects the reality in hospitals. It is in this context that we assessed the nutritional status of children from 2 months to 5 years hospitalized in the pediatric ward of the regional hospital and the Ziguinchor Peace Hospital. Materials and methods: This was a prospective study from June 1 to October 30, 2016. Children aged 2 to 60 months, hospitalized in one of the two services, were included. Children with esdato-ascetic syndrome were not included. Epidemiological, anthropometric data, and associated diagnosis were studied. Results: We included 114 children (70 boys and 44 girls). The average age was 21.9 months [4-59]. Forty-two point one percent (42.1%) of infants <6 months were breastfed exclusively with breast milk. The weaning of children was done early in 55.3%. The mean age of mothers was 26.6 years [17-38]. The socioeconomic level was low in 62.3% of cases. The prevalence of malnutrition averaged 35.5% for underweight; 32.9% for wasting and 32.0% for stunting. Acute respiratory infections (ARI) and acute gastroenteritis were the most common associated conditions. Mean hospital stay was 8 days ± 009 [3-28]. About two thirds of the patients (n = 72) had a hospital stay of more than 7 days. Malnutrition was significantly associated with multiparity, low socioeconomic status, hospital stay of more than 7 days and infectious diseases. Conclusion: Infections and a hospital stay longer than a week are factors favoring malnutrition in children from 2 months to 5 years

    Molecular Diagnostics of Ebola Patient Samples by Institut Pasteur de Dakar Mobile Laboratory in Guinea 2014–2016

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    As part of the laboratory response to the Ebola virus outbreak in Guinea, the Institut Pasteur de Dakar mobile laboratory (IPD-ML) was set up in Donka hospital from 2014 to 2016. EBOV suspected samples collected at Ebola Treatment Centers (ETC) and from community deaths were sent daily to IPD-ML. Analysis was performed using dried oligonucleotide mixes for real-time RT-PCR designed for field diagnostic. From March 2014 to May 2015, a total of 6055 patient samples suspected for EBOV collected from seven regions of Guinea were tested by real-time RT-PCR. These patients’ clinical included serum samples (n = 2537 samples) and swabs (n = 3518 samples) with positivity rates of 36.74 and 6.88% respectively. Females were significantly more affected than males with positivity rates of 22.39 and 17.22% respectively (p-value = 5.721e-7). All age groups were exposed to the virus with significant difference (p-value <= 2.2e-16). The IPD-ML contributed significantly to the surveillance and patient management during the EBOV outbreak in Guinea. Furthermore, dried reagents adapted for field diagnostic of EVD suspect cases could be useful for future outbreak preparedness and response

    Le pneumothorax spontané comme une manifestation évolutive de la polyarthrite rhumatoide: à propos d’une observation clinique et revue de la litterature

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    La polyarthrite rhumatoïde est une maladie systémique inflammatoire caractérisée par une destruction des synoviales articulaires et des lésions systémiques extra articulaires. Les nodules pulmonaires font partie de ces dernières. Leur évolution peut aboutir à un pneumothorax spontané. Nous rapportons le cas d'un adulte jeune au long passé de polyarthrite rhumatoïde qui a présenté deux épisodes de pneumothorax spontané. Il était admis dans notre service, en urgence, pour un pneumothorax droit spontané et massif sur terrain de polyarthrite rhumatoïde au stade de déformation. Il était sous méthotrexate. La radiographie standard du thorax et la tomodensitométrie montraient un décollement pleural complet droit, des nodules et des images excavées sur les deux champs pulmonaires. Il a bénéficié d'un drainage thoracique aspiratif permettant une bonne ré-expansion pulmonaire. Le pneumothorax spontané constitue une manifestation rare des lésions pulmonaire de la polyarthrite rhumatoïde. Il s'agit le plus souvent d'une manifestation évolutive de la maladie mais aussi une circonstance de découverte de cette dernière. L'implication des immunosuppresseurs reste à être prouvée. Ainsi la polyarthrite rhumatoïde doit être considérée dans la recherche étiologique d'un pneumothorax spontané.Pan African Medical Journal 2015; 2
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