Theses towards a new natural philosophy

In this paper I address some philosophical questions regarding the impact quantum mechanics has in the classical conceptions about reality and knowledge. I stress that onto-gnosiological realism still is an option to the issues regarding the relationship between knowledge and reality. Rejecting some radical aspects of Copenhagen interpretation of quantum formalism, I emphasize the advantages of de Broglie’s realistic and causal model. To finish with, I discuss the limits of the Cartesian concept of matter and the split between matter and mind

Characterization of a rare analphoid supernumerary marker chromosome in mosaic

Abstract publicado em: Chromosome Research. 2015;23(Suppl 1):67-8. doi:10.1007/s10577-015-9476-6Analphoid supernumerary marker chromosomes (SMCs) are a rare subclass of SMCs C-band-negative and devoid of alpha-satellite DNA. These marker chromosomes cannot be identified unambiguously by conventional banding techniques alone being necessary to apply molecular cytogenetic methods in favour of a detailed characterization. In this work we report an analphoid SMC involving the terminal long arm of chromosome 7, in 9 years-old boy with several dysmorphic features and severe development delay. Cytogenetic analysis revealed a mosaic karyotype with the presence of an extra SMC, de novo, in 20 % of lymphocytes and 73 % of fibroblast cells. FISH analysis with alpha-satellite probes for all chromosomes, whole chromosome painting probe for chromosome 7, and D7S427 and TelVysion 7q probes, allowed establishing the origin of the SMC as an analphoidmarker resulting of an invdup rearrangement of 7q36-qter region. Affimetrix CytoScan HD microarray analysis, redefined the SMC to arr[hg19] 7q35(143696249-159119707)×2~3, which correspond to a gain of 15.42 Mb and encloses 67 OMIM genes, 16 of which are associated to disease. This result, combined with detailed clinical description, will provide an important means for better genotype-phenotype correlation and a more suitable genetic counselling to the patient and his parents, despite the additional difficulty resulting from being a mosaic (expression varies in different tissues). Analphoid SMCs derived from chromosome 7 are very rare, with only three cases reported so far. With this case we hope contribute to a better understanding of this type of chromosome rearrangements which are difficult for genetic counselling

Razón práctica : reflexiones husserlianas

En este ensayo intento hablar de varias tesis de Husserl relativas al concepto de norma y de ciencia normativa. Confrontando a Husserl con la teoría de la norma de Wundt, con la tesis acerca de la justicia de Kelsen y con la afirmación de Schmitt de que los conceptos modernos de pensamiento político son conceptos teológicos secularizados, trato de mostrar lo que el pensamiento de Husserl tiene que decir acerca de todos estos temas. Finalmente, hablo de varios problemas acerca del propio concepto de norma a la luz de la distinción de Searle entre reglas regulativas y reglas constitutivas

Tempo objectivo e experiência do tempo : a fenomenologia husserliana do tempo perante a relatividade restrita de A.Einstein

In this paper, I start with the opposition between the husserlian project of a phenomenology of the experience of time, started in 1905, and the mathematical and physical theory of time, as it comes out from the special theory of relativity, by Einstein, in the same year. Although the contrast between the two approaches is apparent, my aim is to show that the original program of Husserl’s time theory is the constitution of an objective time and a time of the world, starting from the intuitive giveness of time, i.e., from time as it appears. To show this, I stress the structural similarity between the original question of time, by Husserl, and the problem of a phenomenology of the space constitution, as it was first developed in the husserlian manuscripts of the XIX century, in which we find the threefold question of the origin of our space representation, of the geometrization of intuitive space and the constitution of transcendent world space. Finally, I reconsider some of Husserl’s main theses about the phenomenological constitution of objective time in the light of the main results of special relativity timetheory, introducing several corrections to central assumptions that underlie Husserl’s theory of time

KANT’S INSIGHT AND KANT’S CONCEPT OF A TRANSCENDENTAL LOGIC

I examine the Kantian concept of a transcendental logic, stressing its novelty and richness. I discuss the relationship between logical form of judgments and pure concept of the understanding, trying to elucidate how the pure concept Is embedded in the form of judgments. Exploring this issue, I construe transcendental logic as a part of formal ontology, pointing at the end of the article to some limitations that hinder the Kantian concept of a formal theory of the “object In general”

Vers une phénoménologie de la normativité. Une circonscription préliminaire du domaine

I discuss, from a phenomenological point of view, the distinction between judgments and norms. I stress the limits of the Husserlian canonical analysis in order to rightly account for the sense and content of normative intentionality. Based on some Kelsenian insights, I draw a clear distinction between judgments and norms, criticizing some classical trends coming from Husserl himself that consider norms as a kind of intentionality founded upon objectifying acts. However, taking distance from Kelsen, Kaufmann, and Cossio, I stress that the ought-proposition (Sollsatz) cannot be a good rendering of the sense-content of norms, based on the phenomenological distinction between the intentional matter and the quality of intentional acts. Finally, I propose my own account based on the concept of “ductive force”. I stress that the ductive force of norms cannot be identified with simple coercion. I show that there is, even inside the juridical sphere, a variety of ductive forces, going from sheer coercion to council and recommendation. To end, I stress the centrality of the concept of “ductive force” for a phenomenology of the social world