5,319 research outputs found
National Traitors In Chicano Culture and Literature: Malinche and Chicano Homosexuals
This article examines the literary representation of a treatment of homosexuality in Mexican/Chicano culture. In this study, Alvarez argues that this cultural treatment is rooted in the gender paradigm central to Mexican/Chicano culture: the narrative of La Malinche
Integration of Local Poetic Voices: an Interview with Lawson Fusao Inada
An interview with Lawson Fusoa Inad
Analysis of Balmer Profiles of early type stars
The spectral energy distribution (SED) of recent star formation regions is
dominated by the more massive and early stars (O and B types). These stars show
large and very significant absorption features, the most prominent being the
recombination lines of H, HeI and HeII. In particular, the shape of their
profiles are very dependent on the luminosity of the star. We have explored the
potential use of high resolution profiles to discriminate between different
luminosity classes and spectral types, by using profiles of the He and Balmer
lines. We have calculated growth curves for each of the lines and their
dependence on gravity and effective temperature. We show some of these
theoretical growth curves and our preliminary conclusions are analyzed and
discussed.Comment: 1 pag, Contribution to the conference "Cosmic Evolution and Galaxy
Formation: Structure, Interactions and Feedback", Nov. 1999 (Puebla, Mexico),
to be published in ASP. Conf. Series, Eds. J. Franco, E. Terlevich. O.
Lopez-Cruz, I. Aretxag
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Experimental measurement of endocytosis in fungal hyphae.
The present study examines the notion that polarized exocytosis in the tips of growing hyphae creates an excess of plasma membrane and thus the need for its removal by endocytosis. To measure endocytosis experimentally, we developed a photobleaching (FRAP) procedure to count endocytic events in hyphae of Neurospora crassa carrying a fluorescent tag on the actin-binding protein fimbrin (FIM-1-GFP). Given 40 nm as the average diameter of endocytic vesicles, we calculated that about 12.5% of the plasma membrane discharged in the apex becomes endocytosed in the subapex. According to our calculations, the GFP-tagged hyphae of N. crassa, measured under the constrained conditions of confocal microscopic examination, needed about 8800 vesicles/min to extend their plasma membrane or about 9800/min, if we include predicted demands for cell wall growth and extracellular secretion. Our findings support the notion that exocytosis and endocytosis operate in tandem with the latter serving as a compensatory process to remove any excess of plasma membrane generated by the intense exocytosis in the hyphal tips. Presumably, this tandem arrangement evolved to support the hallmark features of fungi namely rapid cell extension and abundant secretion of hydrolytic enzymes
Structural Capital Management: A Guide For Indicators
Intellectual Capital is of vital importance, both for the scientific community and business reality. For this reason, over the past decades its relevance has rapidly increased. Within Intellectual Capital (from here on IC), Structural Capital (from here on, SC) plays an outstanding paper, given that is represents the part of knowledge that the organization is able to explicit, systematize and internalize and that, initially, is latent in employees or teams. This type of capital allows for organizational effectiveness improvement through the transmission of knowledge.The objectives of this paper is, first, to identify the elements of IC that help to guarantee the success of companies belonging to a given sector, paying special attention to the contributions of SC to IC. Second, and after observing that most existing papers are centered only on the measurement of SC and, therefore, leave aside elements regarding its management, our proposal fills this gap and includes various general indicators for SC that may help to manage it adequately. The basic aim is to allow managers themselves to choose the most adequate indicators within those presented, taking into account, of course, characteristics, objectives and strategies of the companies they manage
La selección de la variable principal y su relación con el tamaño de la muestra en los ensayos clínicos de biomateriales
La eficacia y la seguridad en la utilización de un biomaterial se demuestran, finalmente, en ensayos
clínicos controlados, ya que la utilización de un grupo control es la única forma de evaluar realmente
el efecto del nuevo tratamiento respecto a la regresión espontánea o en relación con un tratamiento ya
establecido.
El cálculo del número de sujetos necesario dependerá de la variable principal escogida para
evaluar el tratamiento, debido a que su selección incide directamente en la eficacia y el beneficio d
esperado con el nuevo tratamiento. El tamaño de la muestra depende, además, del riesgo de concluir
una diferencia que no existe (a) y del riesgo de no poner en evidencia un beneficio al menos
igual d aunque él exista (b).
La inclusión de una cantidad excesiva de pacientes en un ensayo trae un alargamiento innecesario
del periodo de inclusión, gasto excesivo de materiales y puede involucrar hasta problemas éticos.
Por el contrario, una cantidad insuficiente puede traer como resultado la imposibilidad de
demostrar científicamente la hipótesis planteada.
En este trabajo se observa como, la selección adecuada de la variable principal permite demostrar
estadísticamente la superioridad del adhesivo tisular TISUACRYL, respecto a la sutura en dos
ensayos clínicos en Cirugía Bucal, con la inclusión del mínimo número de pacientes.Peer Reviewe
Planar Chirality: A Mine for Catalysis and Structure Discovery
[EN] Planar chirality is one of the most fascinating expressions of chirality, which is exploited by nature to lock three-dimensional chiral conformations and, more recently, by chemists to create new chiral reagents, catalysts, and functional organic materials. Nevertheless, the shortage of procedures able to induce and secure asymmetry during the generation of these unique chiral entities has dissuaded chemists from exploiting their structural properties. This Minireview intends to illustrate the limited but remarkable catalytic methods that have been reported for the production of planar chirality in strained molecules and serve as a source of inspiration for the development of new unconventional procedures, which are expected to appear in the near future.We thank the University of the Basque Country UPV/EHU (UFIQOSYC 11/22), the Basque Government (grant IT-1236-19) and Ministerio de Ciencia e Innovation (grant PID2019-109633GB-C21), Spain, for their continuous financial support
Digital competences in the social media program for older adults in vulnerable contexts
In this study we analyze the effects of the program of incursion in Social Networks in Digital Competences as part of an experimental
investigation with 40 adults (rank: 81 - 92 years of age) from vulnerable contexts of a Latin state. 50 educational activities based on the use of Facebook,
WhatsApp, Twitter and Gmail were applied as essential elements of virtual communication. These allowed obtaining statistical significance in digital
competencies of the experimental group, especially in more than 60% of participating subjects, both in the ability to manage technological resources as
well as in the interrelation through the internet (social networks). The study recognizes its contribution in the opportunity to generate digital inclusion in
the elderly in states of digital abandonment
Analysis Of Employment And Job Profiles Of Renewable Energy: The Case Of The European Union
In recent years, the European Union (EU) is involved in a process of intense development of renewable energy.One of the basic aims is to reduce atmospheric pollution.However, this type of production technologies also entails important social-economic implications including employment creation.The objective of this paper is to analyze the creation of employment due to the development of the main clean production technologies in the EU.In addition, we will study the main characteristics of the necessary job profiles in this new industry where their main skills and educational background will be analyzed
Post-Translational Modification of MR Activity
The mineralocorticoid receptor (MR) is a ligand-activated transcription factor that transduces the effects of aldosterone and glucocorticoids in a tissue- and cell type-specific ways. Differential regulation of MR by post-translational modifications (PTMs) has been proposed to play a key role in modulating its function. In addition, modifications of other proteins that physically or functionally interact with MR add an additional layer of regulation to aldosterone or glucocorticoid signaling. In this chapter, we will summarize the main post-translational modifications of MR described so far, discussing their possible implications in the physiological and pathological roles of the receptor. We will also discuss post-translational modulation of other proteins impacting MR function such as heat shock protein 90 or 11ß-hydroxysteroid dehydrogenase type 2
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