Correction of zinc deficiency in children with type 1 diabetes mellitus

Scientific supervisor: N.V. GluschenkoThe most important in the pathogenesis of diabetes mellitus type 1 (DM-1) among trace elements has zinc (Zn). With the participation of Zn ions is an allocation of insulin from β-cells of Langerhans islands, the inclusion of insulin to transport complex, inhibition of insulinazy. Therefore, zinc deficiency can be considered as one of the factors of development and labile course of DM-1 in children. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/2749

Ionic liquid-assisted hydrothermal synthesis of a biocompatible filler for photo-curable dental composite : from theory to experiment

Nanostructured hydroxyapatite (HA) is a new class of biocompatible fillers which has been recently utilized in bio hybrid materials by virtue of its excellent tissue bioactivity and biocompatibility. However, the need for higher thermal stability, solubility, surface bioactivity, radiopacity, and remineralization ability suggests a divalent cation substitution of HA for use in light curable dental restorative composites. In this work, structural and optical properties of Sr-doped hydroxyapatite were studied using first-principle calculations based on density functional theory (DFT). Next, Sr-doped hydroxyapatite (HA) was prepared via a new ionic liquid-assisted hydrothermal (ILH) route. Samples were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM)/energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), dynamic light scattering (DLS), Brunauer-Emmett-Teller (BET) surface area analysis, and cell viability. The obtained experimental data showed that the nucleation and crystal growth process controlled by [BMIM]Br molecules results in uniform products with small and regular particles and high specific surface areas. Finally, cytotoxicity tests showed that the as-prepared Sr-doped HA nanoparticles have good biocompatibility (â¥91%), confirming their potential for use in photo-curable dental restorative composites

Designing the Prohibitive Model of the Corruption Based on the Islamic Doctrines

The study aimed to design the prohibitive model of the corruption based on the Islamic doctrines. The purposes of the study included designing and testing the model. The research has used the mixed method (qualitative-quantitative) from expletory type. The statistical population (79 people) consisted of the managers of four headquarters of the anti-corruption committee of industry, mine and commerce.  Cochran’s sample size formula demonstrated 65 people.  The researcher-made questionnaire was used to collect the data. The validity of the questionnaire was measured and confirmed by some professors and masters of Islamic sciences and seminary (who have reached the juridical –religious leadership) and the managers of the anti-corruption (who have acted in the field for 10 years). The reliability of the questionnaire has been estimated %77 through Cronbach's Alpha coefficient. To analyze and obtain the final model, the analysis test of the structural equations (PLS software) was used. The results show that the effect of the exaltation on the prohibition of the corruption, of the prohibition on conflict, and of the exaltation on the treatment through the prohibition are 0.694(9.592), 0.431(2.762), 0.692(10.31), respectively. All of them indicate a significant relation. The effect of the moral and spiritual qualities on the solving mechanism, on the controlling mechanism, on the selective - professional mechanism, on the structural mechanism, on the tact, and on the avoidance of the avarice have been evaluated 0.426 (3.922), 0.691 (12.248), 0.690 (11.215), 0.653 (11.825), respectively. Consequently, the factors of the exaltation and avoidance have most effect on the prohibition of the corruption. Keywords: designing a model, prohibition, avoidance, corruption, exaltation, Islamic doctrines

Reconfiguration of Distribution Networks with Presence of DGs to improving the Reliability

In this paper, the network reconfiguration in the presence of distributed generation units with the aim of improving the reliability of the network is studied. For this purpose four reliability parameters in the objective function are considered, which is average energy not supplied system average interruption frequency index, system average interruption duration index and momentary average interruption frequency index. The new method will be normalized objective function. Another suggestion of this paper are considering the different fault rates, locating time of faults type and prioritization of customers based on their importance. This nonlinear problem has optimized by particle swarm optimization (PSO) algorithm

Comparison of Renal Safety of Tenofovir and Telbivudine in Chronic Hepatitis B Patients: A Real World Study in Indonesia

Introduction. Tenofovir disoproxil fumarate (tenofovir) and telbivudine are two available nucleos(t)ide analogue (NA) for the treatment of chronic hepatitis B (CHB) patients. Tenofovir has been known as a nephrotoxic agent in HIV patients, but still controversy in CHB patients. On the other hand, telbivudine had a renal protective effect and increased estimated glomerular filtration rate (eGFR). This studi aimed to address the renal safety of tenofovir and telbivudine in Indonesian patients. Method. A retrospective cohort study design was conducted in CHB patients who prescribed with tenofovir or telbivudine from January 2013 to December 2016. Patients who met the inclusion and exclusion criteria were followed up for one year. The serial evaluation of creatinine serum was collected in week-24 and week-48 after the administration of tenofovir or telbivudine. Results. Among CHB patients, 68 and 62 patients that prescribed with tenofovir or telbivudine, respectively, were enrolled in this study. Serum creatinine level was increased in tenofovir group from 0.88 (SD 0.17) mg/dL at baseline to 0.93 (SD 0.22) mg/dL after 24 weeks (p = 0.02), but creatinine trend to reach plateau after 48 weeks. However, in telbivudine group, serum creatinine level was decreased from 0.85 (SD 0.21) mg/dL at baseline to 0.80 (SD 0.18) mg/dL after 48 weeks (p = 0.003). Conclusion. Tenofovir is associated with the increased of creatinine serum and decreased of eGFR in CHB patients with eGFR ≥60 mL/menit/1,73 m2

Reconfiguration of Distribution Networks with Presence of DGs to Improving the Reliability

In this paper, the network reconfiguration in the presence of distributed generation units with the aim of improving the reliability of the network is studied. For this purpose four reliability parameters in the objective function are considered, which is average energy not supplied system average interruption frequency index, system average interruption duration index and momentary average interruption frequency index. The new method will be normalized objective function. Another suggestion of this paper are considering the different fault rates, locating time of faults type and prioritization of customers based on their importance. This nonlinear problem has optimized by particle swarm optimization (PSO) algorithm

Pengaruh Model Pembelajaran Kooperatif Tipe Talking Stick terhadap Aktivitas Belajar dan Hasil Belajar Siswa Kelas XI Ipa Man 2 Banyumas

Penelitian ini bertujuan untuk mengetahui yaitu: (1) mengetahui perbedaan hasil belajar antara kelompok siswa yang dibelajarkan dengan model pembelajaran kooperatif tipe talking stick dan kelompok siswa yang dibelajarkan dengan model konvensional. (2) mengetahui pengaruh model pembelajaran kooperatif tipe talking stick terhadap aktivitas belajar siswa. (3) mengetahui pengaruh model pembelajaran kooperatif tipe talking stick terhadap hasil belajar siswa. Metode peelitian yang digunakan adalah eksperimen dengan rancangan non-equivalent group desain. Pengambilan sampel menggunakan teknik purposive sampel. Adapun sampel peelitian adalah kelas XI IPA 1 sebagai kelas eksperimen dan kelas XI IPA 5 sebagai kelas control. Data hasil belajar diperoleh melalui pre-test dan post-test, dan data aktivitas belajar melalui lembar kuesioner. Data dianalisis menggunakan statistic uji t (independent t-test). Hasil penelitian diperoleh: (1) Terdapat perbedaan hasil belajar secara signifikan antara siswa yang dibelajarkan melalui model pembelajaran kooperatif tipe talking stick dengan siswa yang dibelajarkan melalui model konvensional. (2) Model pembelajaran kooperatif tipe talking stick tidak terdapat pengaruh yang signifikan terhadap hasil belajar. (3) Model pembelajaran kooperatif tipe talking stick berpengaruh signifikan terhadap hasil belajar