Evaluation of maxillary sinus anatomical variations and pathologies in elderly, young, posterior dentate and edentulous patient groups with cone-beam computed tomography

Background: The aim of this study was to evaluate the frequency of maxillary sinus pathologies and anatomic variations in elderly and edentulous patients by using cone-beam computed tomography (CBCT). Materials and methods: The study included elderly and young patient groups. The elderly group involved posterior edentulous and dentate patients. CBCT images were assessed, and the presence of any pathological findings, septa, accessory maxillary ostium, and Haller cell in each maxillary sinus were recorded according to the groups. Chi-square test was used to analyse the intergroup differences (p < 0.05). Results: There was no statistically difference between the young and elderly groups regarding the presence of a pathology (p = 0.077) and septa (p = 0.37), whereas accessory ostium (p = 0.009) was more common and Haller cell (p = 0.000) was less common in the elderly group when compared to the young group. There was no significant difference between the edentulous and dentate group regarding the presence of a pathology (p = 0.39), septation (p = 0.69) and Haller cell (p = 0.75); accessory ostium rate was found to be increased (p = 0,015) in edentulous patients. Conclusions: It was observed that the frequency of accessory maxillary ostium was increased in elderly, especially in edentulism. And the frequency of Haller cell was found to be decreased in elderly patients

Anti-fungal bandages containing cinnamon extract

© 2019 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.Cinnamon-containing polycaprolactone (PCL) bandages were produced by pressurised gyration and their anti-fungal activities against Candida albicans were investigated. It was found that by preparing and spinning polymer solutions of cinnamon with PCL, fibres capable of inhibiting fungal growth could be produced, as observed in disk diffusion tests for anti-fungal susceptibility. Fascinatingly, compared with raw cinnamon powder, the novel cinnamon-loaded fibres had outstanding long-term activity. The results presented here are very promising and may indeed accelerate a new era of using completely natural materials in biomedical applications, especially in wound healing.Peer reviewe

Correlation effects and orbital magnetism of Co clusters

Recent experiments on isolated Co clusters have shown huge orbital magnetic moments in comparison with their bulk and surface counterparts. These clusters hence provide the unique possibility to study the evolution of the orbital magnetic moment with respect to the cluster size and how competing interactions contribute to the quenching of orbital magnetism. We investigate here different theoretical methods to calculate the spin and orbital moments of Co clusters, and assess the performances of the methods in comparison with experiments. It is shown that density functional theory in conventional local density or generalized gradient approximations, or even with a hybrid functional, severely underestimates the orbital moment. As natural extensions/corrections we considered the orbital polarization correction, the LDA+U approximation as well as the LDA+DMFT method. Our theory shows that of the considered methods, only the LDA+DMFT method provides orbital moments in agreement with experiment, thus emphasizing the importance of dynamic correlations effects for determining fundamental magnetic properties of magnets in the nano-size regime

Immunization of Rainbow Trout (Oncorhynchus mykiss) against Lactococcus garvieae Using Vaccine Mixtures

The effectiveness of vaccine mixtures against lactococcosis was tested in rainbow trout (Oncorhynchus mykiss). The M1 strain of Lactococcus garvieae, isolated from a recent outbreak of lactococcosis at a rainbow trout farm in Turkey, was used in a trial comparing five immuniza- tion treatments: (a) formalin inactivated bacterin (vaccine), (b) the above bacterin together with Freund’s Incomplete Adjuvant (FIA), (c) the bacterin combined with β-glucan, (d) β-glucan only, and (e) phosphate buffered saline-PBS (control). Fish were given intrapritoneal injections and challenged by exposure to the bacteria 30, 75, or 125 days after vaccination. In fish exposed to the bacteria 30 days after injection, the relative percent survival (RPS) was 88.89% in the group that received only bacterin and 100% in the group that received the bacterin combined with FIA. Immunity remained high in the bacterin+FIA group, as the RPS in this group remained 100% in fish challenged at 75 days, significantly higher than in all other groups. In fish exposed to the bacteria 125 days after vaccination, the RPS was 54.55% in fish vaccinated with the bacterin only and 84.84% in fish vaccinated with bacterin+FIA. In the group that received only β-glucan, immunity did not improve after vaccination. Micro-agglutination tests of serums showed that immunized fish produced antibodies at high titers within 30 days. In short, the formalin-inacti- vated M1 strain provided longer lasting protection against Lactococcus garvieae in rainbow trout when combined with FIA than when administered alone or with β-glucan

Evaluation of localisation of mandibular foramen in patients with mandibular third molar teeth using cone-beam computed tomography

Background: It is important to know the correct anatomical location of the mandibular foramen to obtain successful anaesthesia of inferior alveolar nerve and to prevent injury to the mandibular vessels and nerve, during a variety of oral and maxillofacial surgical procedures. The aim of this study is to evaluate localisation of the mandibular foramen in patients with the third molars using cone-beam computed tomography (CBCT). Materials and methods: Cone-beam computed tomography was used to determine the location of the mandibular foramen in 67 patients (totally 99 sides) with unilateral or bilateral impacted mandibular third molars. Results: The distance from the posterior border of the mandibular ramus to mandibular foramen did not differ significantly among the other angulations. But the difference between vertical and horizontal angulation of the impactedmandibular third molars according to ‘fd’ values (the shortest distance between mandibular foramen and the posterior border of mandibular ramus) was found to be statistically significant (p < 0.05). Conclusions: The present study provides new information to the literature concerning relationship between the location of the mandibular foramen and the mandibular third molars

Knowledge Annotation within Research Data Management System for Oxygen-Free Production Technologies

The comprehensive implementation of digital technologies in product manufacturing leads to changes in engineering processes and requires new approaches to data management. An important role belongs to the processes of organizing the collection, storage and reuse of research data obtained and used in the process of product, system or technology development, taking into account the FAIR data principles. This article describes a Research Data Management System for the organization of documentation and measurement requests in the research and development of new oxygen-free production technologies

Kinetic Release Studies of Antibiotic Patches for Local Transdermal Delivery.

This study investigates the usage of electrohydrodynamic (EHD)-3D printing for the fabrication of bacterial cellulose (BC)/polycaprolactone (PCL) patches loaded with different antibiotics (amoxicillin (AMX), ampicillin (AMP), and kanamycin (KAN)) for transdermal delivery. The composite patches demonstrated facilitated drug loading and encapsulation efficiency of drugs along with extended drug release profiles. Release curves were also subjected to model fitting, and it was found that drug release was optimally adapted to the Higuchi square root model for each drug. They performed a time-dependent and diffusion-controlled release from the patches and followed Fick's diffusion law by the Korsmeyer-Peppas energy law equation. Moreover, produced patches demonstrated excellent antimicrobial activity against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) strains, so they could be helpful in the treatment of chronic infectious lesions during wound closures. As different tests have confirmed, various types of antibiotics could be loaded and successfully released regardless of their types from produced BC/PCL patches. This study could breathe life into the production of antibiotic patches for local transdermal applications in wound dressing studies and improve the quality of life of patients

Fixed point results for generalized cyclic contraction mappings in partial metric spaces

Rus (Approx. Convexity 3:171–178, 2005) introduced the concept of cyclic contraction mapping. P˘acurar and Rus (Nonlinear Anal. 72:1181–1187, 2010) proved some fixed point results for cyclic φ-contraction mappings on a metric space. Karapinar (Appl. Math. Lett. 24:822–825, 2011) obtained a unique fixed point of cyclic weak φ- contraction mappings and studied well-posedness problem for such mappings. On the other hand, Matthews (Ann. New York Acad. Sci. 728:183–197, 1994) introduced the concept of a partial metric as a part of the study of denotational semantics of dataflow networks. He gave a modified version of the Banach contraction principle, more suitable in this context. In this paper, we initiate the study of fixed points of generalized cyclic contraction in the framework of partial metric spaces. We also present some examples to validate our results.S. Romaguera acknowledges the support of the Ministry of Science and Innovation of Spain, grant MTM2009-12872-C02-01.Abbas, M.; Nazir, T.; Romaguera Bonilla, S. (2012). Fixed point results for generalized cyclic contraction mappings in partial metric spaces. Revista- Real Academia de Ciencias Exactas Fisicas Y Naturales Serie a Matematicas. 106(2):287-297. https://doi.org/10.1007/s13398-011-0051-5S2872971062Abdeljawad T., Karapinar E., Tas K.: Existence and uniqueness of a common fixed point on partial metric spaces. Appl. Math. Lett. 24(11), 1894–1899 (2011). doi: 10.1016/j.aml.2011.5.014Altun, I., Erduran A.: Fixed point theorems for monotone mappings on partial metric spaces. Fixed Point Theory Appl. article ID 508730 (2011). doi: 10.1155/2011/508730Altun I., Sadarangani K.: Corrigendum to “Generalized contractions on partial metric spaces” [Topology Appl. 157 (2010), 2778–2785]. Topol. Appl. 158, 1738–1740 (2011)Altun I., Simsek H.: Some fixed point theorems on dualistic partial metric spaces. J. Adv. Math. Stud. 1, 1–8 (2008)Altun I., Sola F., Simsek H.: Generalized contractions on partial metric spaces. Topol. Appl. 157, 2778–2785 (2010)Aydi, H.: Some fixed point results in ordered partial metric spaces. arxiv:1103.3680v1 [math.GN](2011)Boyd D.W., Wong J.S.W.: On nonlinear contractions. Proc. Am. Math. Soc. 20, 458–464 (1969)Bukatin M., Kopperman R., Matthews S., Pajoohesh H.: Partial metric spaces. Am. Math. Monthly 116, 708–718 (2009)Bukatin M.A., Shorina S.Yu. et al.: Partial metrics and co-continuous valuations. In: Nivat, M. (eds) Foundations of software science and computation structure Lecture notes in computer science vol 1378., pp. 125–139. Springer, Berlin (1998)Derafshpour M., Rezapour S., Shahzad N.: On the existence of best proximity points of cyclic contractions. Adv. Dyn. Syst. Appl. 6, 33–40 (2011)Heckmann R.: Approximation of metric spaces by partial metric spaces. Appl. Cat. Struct. 7, 71–83 (1999)Karapinar E.: Fixed point theory for cyclic weak $${\phi}$$ -contraction. App. Math. Lett. 24, 822–825 (2011)Karapinar, E.: Generalizations of Caristi Kirk’s theorem on partial metric spaces. Fixed Point Theory Appl. 2011,4 (2011). doi: 10.1186/1687-1812-2011-4Karapinar E.: Weak $${\varphi}$$ -contraction on partial metric spaces and existence of fixed points in partially ordered sets. Math. Aeterna. 1(4), 237–244 (2011)Karapinar E., Erhan I.M.: Fixed point theorems for operators on partial metric spaces. Appl. Math. Lett. 24, 1894–1899 (2011)Karpagam S., Agrawal S.: Best proximity point theorems for cyclic orbital Meir–Keeler contraction maps. Nonlinear Anal. 74, 1040–1046 (2011)Kirk W.A., Srinavasan P.S., Veeramani P.: Fixed points for mapping satisfying cylical contractive conditions. 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Temperament Systems Influence Emotion Induction but not Makam Recognition Performance in Turkish Makam Music

We tested how induced emotions and Turkish makam recognition are influenced by participation in an ear training classes, and if either is influenced by the temperament system employed. The ear training class was attended by 19 music students and was based on the Hicaz makam presented as a between-subjects factor in either unfamiliar Turkish Original Temperament (OT, pitches unequally divided into 24 intervals) or familiar Western Equal Temperament (ET, pitches equally divided into 12 intervals). Before the and after the class, participants listened to 20 music excerpts from five different Turkish makams (in both OT and ET versions). Emotion-induction was assessed via GEMS-25, and participants were also asked to identify the makam that was present in the excerpt. The unfamiliar original temperament was experienced as less vital and more uneasy before the ear training class, and recognition of the Hicaz makam increased after ear training classes (independent of the temperament system employed). Results suggest that unfamiliar temperament systems are experienced as less vital and more uneasy. Furthermore, being exposed to this temperament system for just one hour does not seem to be enough to change participants’ mental representations of it or their emotional responses to it

Neural development features: Spatio-temporal development of the Caenorhabditis elegans neuronal network

The nematode Caenorhabditis elegans, with information on neural connectivity, three-dimensional position and cell linage provides a unique system for understanding the development of neural networks. Although C. elegans has been widely studied in the past, we present the first statistical study from a developmental perspective, with findings that raise interesting suggestions on the establishment of long-distance connections and network hubs. Here, we analyze the neuro-development for temporal and spatial features, using birth times of neurons and their three-dimensional positions. Comparisons of growth in C. elegans with random spatial network growth highlight two findings relevant to neural network development. First, most neurons which are linked by long-distance connections are born around the same time and early on, suggesting the possibility of early contact or interaction between connected neurons during development. Second, early-born neurons are more highly connected (tendency to form hubs) than later born neurons. This indicates that the longer time frame available to them might underlie high connectivity. Both outcomes are not observed for random connection formation. The study finds that around one-third of electrically coupled long-range connections are late forming, raising the question of what mechanisms are involved in ensuring their accuracy, particularly in light of the extremely invariant connectivity observed in C. elegans. In conclusion, the sequence of neural network development highlights the possibility of early contact or interaction in securing long-distance and high-degree connectivity