Clinical Management in Diagnosis and Treatment of the Iron Deficiency Anemia in Adults: Systemic Review

This study aimed at exploring with a systematic review the clinical management in diagnosis and treatment of the iron deficiency anemia in adults, as the iron deficiency is the most frequent cause of anemia worldwide. And it impairs quality of life, increases asthenia and can lead to clinical worsening of patients. In addition, iron deficiency has a complex mechanism whose pathologic pathway is recently becoming better understood. This review summarizes the current knowledge regarding diagnostic algorithms for iron deficiency anemia. The majority of aetiologies occur in the digestive tract, and justify morphological examination of the gut. First line investigations are upper gastrointestinal endoscopy and colonoscopy, and when negative, the small bowel should be explored; newer tools such as video capsule endoscopy have also been developed. The treatment of iron deficiency is aetiological if possible and iron supplementation whether in oral or in parenteral form.

Smart fuzzy logic control of photovoltaic system: Case study Kingdom of Saudi Arabia

Robust controls of photovoltaic (PV) system applications that include modular multilevel inverter (MMI) for interfacing stand-alone and grid-connected operating modes are investigated in this paper to overcome interfacing problems of two-level and three-level inverters. The MMI provides high-quality voltage, current, and power signals without additional filters, which reduces complexity and cost of interface circuits. A new control method of active and reactive power has been introduced for PV systems to get maximum power point (MPP) in various climatic circumstances. The steady-state and dynamic performances of MMI are investigated using MATLAB/Simulink. A fuzzy logic control is proposed to track the MPP utilizing the perturb and observe (P&O) technique. A fair comparison between fuzzy logic control and proportional integral (PI) control was conducted using MATLAB/Simulink. The fuzzy logic controller for obtaining MPPT by P&O method is proposed to get fast and accurate results. The obtained results obvioused that the fuzzy logic controller is quick accessing MPP than PI controller. A simple LC filter can achieve minimum harmonics provided by total harmonic distortion (THD) of MMI within IEEE limit. The PV system for standalone and grid-connected modes is being tested under climatic conditions in the city of Tabuk, Kingdom of Saudi Arabia (KSA). © 2023 Institute of Advanced Engineering and Science. All rights reserved

The radiative width of the Hoyle state from γ\gamma-ray spectroscopy

The cascading 3.21 MeV and 4.44 MeV electric quadrupole transitions have been observed from the Hoyle state at 7.65 MeV excitation energy in $^{12}$C, excited by the $^{12}$C(p,p$^{\prime}$) reaction at 10.7 MeV proton energy. From the proton-$\gamma$-$\gamma$ triple coincidence data, a value of ${\Gamma_{\rm rad}}/{\Gamma}=6.2(6) \times 10^{-4}$ was obtained for the radiative branching ratio. Using our results, together with ${\Gamma_{\pi}^{E0}}/{\Gamma}$ from Eriksen et al., Phys. Rev. C 102, 024320 and the currently adopted $\Gamma_{\pi}(E0)$ values, the radiative width of the Hoyle state is determined as $\Gamma_{\rm rad}=5.1(6) \times 10^{-3}$ eV. This value is about 34% higher than the currently adopted value and will impact on models of stellar evolution and nucleosynthesis.Comment: 6 pages, 6 figure

Identification of Significant \u3cem\u3eE\u3c/em\u3e0 Strength in the 2\u3csub\u3e2\u3c/sub\u3e\u3csup\u3e+\u3c/sup\u3e → 2\u3csub\u3e1\u3c/sub\u3e\u3csup\u3e+\u3c/sup\u3e Transitions of \u3csup\u3e58,60,62\u3c/sup\u3eNi

The E0 transition strength in the 22+ → 21+ transitions of 58,60,62Ni have been determined for the first time following a series of measurements at the Australian National University (ANU) and the University of Kentucky (UK). The CAESAR Compton-suppressed HPGe array and the Super-e solenoid at ANU were used to measure the δ(E2/M1) mixing ratio and internal conversion coefficient of each transition following inelastic proton scattering. Level half-lives, δ(E2/M1) mixing ratios and γ-ray branching ratios were measured at UK following inelastic neutron scattering. The new spectroscopic information was used to determine the E0 strengths. These are the first 2+ → 2+ E0 transition strengths measured in nuclei with spherical ground states and the E0 component is found to be unexpectedly large; in fact, these are amongst the largest E0 transition strengths in medium and heavy nuclei reported to date

Identification of significant E0E0 strength in the 22+→21+2^+_2 \rightarrow 2^+_1 transitions of 58,60,62^{58, 60, 62}Ni

The $E0$ transition strength in the $2^+_2 \rightarrow 2^+_1$ transitions of $^{58,60,62}$Ni have been determined for the first time following a series of measurements at the Australian National University (ANU) and the University of Kentucky (UK). The CAESAR Compton-suppressed HPGe array and the Super-e solenoid at ANU were used to measure the $\delta(E2/M1)$ mixing ratio and internal conversion coefficient of each transition following inelastic proton scattering. Level half-lives, $\delta(E2/M1)$ mixing ratios and $\gamma$-ray branching ratios were measured at UK following inelastic neutron scattering. The new spectroscopic information was used to determine the $E0$ strengths. These are the first $2^+ \rightarrow 2^+$ $E0$ transition strengths measured in nuclei with spherical ground states and the $E0$ component is found to be unexpectedly large; in fact, these are amongst the largest $E0$ transition strengths in medium and heavy nuclei reported to date

Skeletal and dentoalveolar effects of class II malocclusion treatment using bi-maxillary skeletal anchorage: a systematic review

Background: The goal of this systematic review was to assess the available evidence regarding the skeletal and dentoalveolar effects of bi-maxillary skeletal anchorage devices (BMSADs) used in treating growing class II malocclusion patients. Methods: A comprehensive search was conducted on PubMed, Scopus, Science Direct, Web of Science, Cochrane, and LILACS up to November 2021, which was augmented by a manual search. The studies included were clinical trials (RCTs) and/or follow-up observational studies (retrospective and prospective). The outcomes of interest were the skeletal, dentoalveolar, and occlusal treatment-induced changes obtained from pre- and post-cephalometric measurements. The risks of bias of the included studies were assessed using an assessment tool from previous publications. Results: Out of 742 screened articles, only 4 were eligible and thus included in the qualitative synthesis. They showed a moderate overall risk of bias. The results are presented as mean changes in both the study and control groups. All studies reported retrusion of the maxillary base and advancement of the mandible (meaning reduced ANB angle). Three of the included studies reported an increase in the vertical jaw relation, which was contrary to what the fourth study reported. Three studies reported an increase in the maxillary incisors’ inclination or position, while one study reported their retroclination. Proclination of the mandibular incisors happened in two studies, whereas the other two studies reported retroclination. The overjet was reduced in all included studies. Conclusion: Apart from the protrusive effects on the mandible, retrusive effects on the maxilla, and the consequent reduction of the overjet, BMSADs results in inconsistent skeletal and dentoalveolar effects. However, the current evidence is limited due to the variability in the biomechanics of the intermaxillary components, type of anchorage, and comparable groups in the included studies. Further RCTs with more standardized methodologies are highly encouraged. Clinical relevance: BMSADs (using miniscrews or miniplates on both jaws) induces more skeletal than dentoalveolar effects. However, this must be practiced with caution, based on the benefit to risk (surgical insertion) ratio, and the limited evidence available in hand so far. Registration The protocol for this systematic review was registered at the International Prospective Register of Systematic Reviews (PROSPERO, No.: CRD42020199601)

Improved precision on the experimental E0 decay branching ratio of the Hoyle state

Stellar carbon synthesis occurs exclusively via the $3\alpha$ process, in which three $\alpha$ particles fuse to form $^{12}$C in the excited Hoyle state, followed by electromagnetic decay to the ground state. The Hoyle state is above the $\alpha$ threshold, and the rate of stellar carbon production depends on the radiative width of this state. The radiative width cannot be measured directly, and must instead be deduced by combining three separately measured quantities. One of these quantities is the $E0$ decay branching ratio of the Hoyle state, and the current $10$\% uncertainty on the radiative width stems mainly from the uncertainty on this ratio. The $E0$ branching ratio was deduced from a series of pair conversion measurements of the $E0$ and $E2$ transitions depopulating the $0^+_2$ Hoyle state and $2^+_1$ state in $^{12}$C, respectively. The excited states were populated by the $^{12}$C$(p,p^\prime)$ reaction at 10.5 MeV beam energy, and the pairs were detected with the electron-positron pair spectrometer, Super-e, at the Australian National University. The deduced branching ratio required knowledge of the proton population of the two states, as well as the alignment of the $2^+_1$ state in the reaction. For this purpose, proton scattering and $\gamma$-ray angular distribution experiments were also performed. An $E0$ branching ratio of $\Gamma^{E0}_{\pi}/\Gamma=8.2(5)\times10^{-6}$ was deduced in the current work, and an adopted value of $\Gamma^{E0}_{\pi}/\Gamma=7.6(4)\times10^{-6}$ is recommended based on a weighted average of previous literature values and the new result. The new recommended value for the $E0$ branching ratio is about 14% larger than the previous adopted value of $\Gamma^{E0}_{\pi}/\Gamma=6.7(6)\times10^{-6}$, while the uncertainty has been reduced from 9% to 5%.Comment: Accepted for publication as a Regular Article in Phys. Rev. C on July 29 202

Synthesis of novel Fe3O4 nanostructures surrounded by Ti-MOF nanostructures as bioactive and efficient catalysts in three-component synthesis of new pyrazole derivatives

Synthesis and reporting of new nanoparticles with diverse properties is important in chemistry. A one-step, rapid and controllable synthesis of the new Fe3O4 surrounded in Ti-MOF nanostructures was carried out with microwave technology. After identifying and confirming the structure, Fe3O4 surrounded in Ti-MOF nanostructures was used as a suitable catalyst with high thermal resistance and recyclable in a three-component reaction of phenylhydrazine, malononitrile and aldehyde to synthesis novel pyrazole derivatives. Continuing investigations on Fe3O4 surrounded in Ti-MOF nanostructures, its antimicrobial properties were tested on Gram-positive bacterial species, Gram-negative bacterial species and fungi bacterial. Identification of Fe3O4 surrounded in Ti-MOF nanostructures with morphology and size distribution technique (SEM), surface area technique (BET), Infrared spectroscopy (FT-IR), Energy-Dispersive X-ray spectroscopy (EDX/EDX mapping), and Vibrating Sample Magnetometer (VSM) were performed. Synthesized pyrazole derivatives with Fe3O4 surrounded in Ti-MOF nanostructures than previously reported methods have less synthesis time and high efficiency. In antimicrobial properties high effects were observed based on MIC, MBC, and MFC values

E0 transition strength in stable Ni isotopes

Excited states in 58,60,62Ni were populated via inelastic proton scattering at the Australian National University as well as via inelastic neutron scattering at the University of Kentucky Accelerator Laboratory. The Super-e electron spectrometer and the CAESAR Compton-suppressed HPGe array were used in complementary experiments to measure conversion coefficients and δ(E2/M1) mixing ratios, respectively, for a number of 2+→2+ transitions. The data obtained were combined with lifetimes and branching ratios to determine E0,M1, and E2 transition strengths between 2+ states. The E0 transition strengths between 0+ states were measured using internal conversion electron spectroscopy and compare well to previous results from internal pair formation spectroscopy. The E0transition strengths between the lowest-lying 2+ states were found to be consistently large for the isotopes studied