490 research outputs found
HI and star formation in the most metal-deficient galaxies
We present Giant Metrewave Radio Telescope (GMRT) observations for three
(viz., DDO 68, SDSS J2104-0035 and UGC 772) of the six most metal-deficient
actively star-forming galaxies known. Although there is a debate as to whether
these galaxies are undergoing their first episode of star formation or not,
they are `young' in the sense that their ISM is chemically unevolved. In this
regard, they are the nearest equivalents of young galaxies in the early
Universe. All three galaxies, that we have observed, have irregular HI
morphologies and kinematics, which we interpret as either due to tidal
interaction with neighbouring galaxies, or the consequences of a recent merger.
The remaining three of the six most metal-deficient galaxies are also known to
have highly disturbed HI distributions and are interacting. It is interesting
because these galaxies were chosen solely on the basis of their metallicity and
not for any particular signs of interaction. In this sense (i.e., their gas has
not yet had time to settle into a regular disc), one could regard these
extremely metal deficient (XMD) galaxies as `young'. The current star formation
episode is likely to have been triggered by interaction/merger. It is also
possible that the tidal interaction has lead to enhanced mixing with metal-poor
gas in outer disc, and hence to a low gas-phase metallicity in the central
star-forming regions. We also find that in general these galaxies do not show a
one-to-one correspondence between regions of high HI column density and regions
with current star formation. However, to the extent that one can define a
threshold density, its value (~10^{21} atoms cm^{-2}) is similar to that in
galaxies with much higher metallicity.Comment: 11 pages, 11 figures. Accepted for publication in MNRA
Intra-host evolution of multiple genotypes of hepatitis C virus in a chronically infected patient with HIV along a 13-year follow-up period
AbstractThe intra-host evolutionary process of hepatitis C virus (HCV) was analyzed by phylogenetic and coalescent methodologies in a patient co-infected with HCV-1a, HCV-2a, HCV-3a and human immunodeficiency virus (HIV) along a 13-year period.Direct sequence analysis of the E2 and NS5A regions showed diverse evolutionary dynamics, in agreement with different relationships between these regions and the host factors.The Bayesian Skyline Plot analyses of the E2 sequences (cloned) yielded different intra-host evolutionary patterns for each genotype: a steady state of a “consensus” sequence for HCV-1a; a pattern of lineage splitting and extinction for HCV-2a; and a two-phase (drift/diversification) process for HCV-3a.Each genotype evolving in the same patient and at the same time presents a different pattern apparently modulated by the immune pressure of the host.This study provides useful information for the management of co-infected patients and provides insights into the mechanisms behind the intra-host evolution of HCV
Feedback in the local LBG Analog Haro 11 as probed by far-UV and X-ray observations
We have re-analyzed FUSE data and obtained new Chandra observations of Haro
11, a local (D_L=88 Mpc) UV luminous galaxy. Haro 11 has a similar far-UV
luminosity (10^10.3 L_\odot), UV surface brightness (10^9.4 L_\odot kpc^-2),
SFR, and metallicity to that observed in Lyman Break Galaxies (LBGs). We show
that Haro 11 has extended, soft thermal (kT~0.68 keV) X-ray emission with a
luminosity and size which scales with the physical properties (e.g. SFR,
stellar mass) of the host galaxy. An enhanced alpha/Fe, ratio of ~4 relative to
solar abundance suggests significant supernovae enrichment. These results are
consistent with the X-ray emission being produced in a shock between a
supernovae driven outflow and the ambient material. The FUV spectra show strong
absorption lines similar to those observed in LBG spectra. A blueshifted
absorption component is identified as a wind outflowing at ~200-280 km/s.
OVI\lambda\lambda1032,1038 emission, the dominant cooling mechanism for coronal
gas at T~10^5.5 K is also observed. If associated with the outflow, the
luminosity of the OVI emission suggests that <20% of the total mechanical
energy from the supernovae and solar winds is being radiated away. This implies
that radiative cooling through OVI is not significantly inhibiting the growth
of the outflowing gas. In contradiction to the findings of Bergvall et al 2006,
we find no convincing evidence of Lyman continuum leakage in Haro 11. We
conclude that the wind has not created a `tunnel' allowing the escape of a
significant fraction of Lyman continuum photons and place a limit on the escape
fraction of f_{esc}<2%. Overall, both Haro 11 and a previously observed LBG
analogue VV 114, provide an invaluable insight into the X-ray and FUV
properties of high redshift LBGs.Comment: Accepted for publication in ApJ, 40 pages, 17 figure
Resposta da cultura do milho a adubação nitrogenada após cultivo de tremoço branco (Lupinus albus) em duas unidades de solos.
Este trabalho teve por objetivo estudar a influência de dois fertilizantes nitrogenados na produção de grãos e de matéria seca do milho nos solos Podzolico Vermelho Amarelo Latossolico eutrofico (PVLe) e Podzolico Vermelho Amarelo Latossolico distrofico (PVLd), cultivados previamente com tremoço branco
A search for radio supernovae and supernova remnants in the region of NGC1569's super star clusters
We have used MERLIN, at 1.4 and 5 GHz, to search for radio supernovae (RSNe)
and supernova remnants (SNRs) in the unobscured irregular dwarf galaxy NGC1569,
and in particular in the region of its super star clusters (SSCs) A and B.
Throughout NGC1569 we find some 5 RSNe and SNRs but the SSCs and their
immediate surroundings are largely devoid of non-thermal radio sources. Even
though many massive stars in the SSCs are expected to have exploded already,
when compared with M82 and its many SSCs the absence of RSNe and SNRs in and
near A and B may seem plausible on statistical arguments. The absence of RSNe
and SNRs in and near A and B may, however, also be due to a violent and
turbulent outflow of stellar winds and supernova ejected material, which does
not provide a quiescent environment for the development of SNRs within and near
the SSCs.Comment: 9 pages including 7 figures, accepted for publication in A&A Main
Journa
The Green Bank North Celestial Cap Pulsar Survey. IV: Four New Timing Solutions
We present timing solutions for four pulsars discovered in the Green Bank
Northern Celestial Cap (GBNCC) survey. All four pulsars are isolated with spin
periods between 0.26s and 1.84s. PSR J00382501 has a 0.26s
period and a period derivative of ,
which is unusually low for isolated pulsars with similar periods. This low
period derivative may be simply an extreme value for an isolated pulsar or it
could indicate an unusual evolution path for PSR J00382501, such as a
disrupted recycled pulsar (DRP) from a binary system or an orphaned central
compact object (CCO). Correcting the observed spin-down rate for the Shklovskii
effect suggests that this pulsar may have an unusually low space velocity,
which is consistent with expectations for DRPs. There is no X-ray emission
detected from PSR J00382501 in an archival swift observation, which suggests
that it is not a young orphaned CCO. The high dispersion measure of PSR
J1949+3426 suggests a distance of 12.3kpc. This distance indicates that PSR
J1949+3426 is among the most distant 7% of Galactic field pulsars, and is one
of the most luminous pulsars.Comment: 7 pages, 5 figure
MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma
Half of high-risk neuroblastoma patients have MYCN amplification. Here, the authors show that MYCN induces fatty acid uptake and synthesis to support neuroblastoma and inhibition of a fatty acid transporter impairs tumor progression in preclinical models.Neuroblastoma (NB) is a childhood cancer arising from sympatho-adrenal neural crest cells. MYCN amplification is found in half of high-risk NB patients; however, no available therapies directly target MYCN. Using multi-dimensional metabolic profiling in MYCN expression systems and primary patient tumors, we comprehensively characterized the metabolic landscape driven by MYCN in NB. MYCN amplification leads to glycerolipid accumulation by promoting fatty acid (FA) uptake and biosynthesis. We found that cells expressing amplified MYCN depend highly on FA uptake for survival. Mechanistically, MYCN directly upregulates FA transport protein 2 (FATP2), encoded by SLC27A2. Genetic depletion of SLC27A2 impairs NB survival, and pharmacological SLC27A2 inhibition selectively suppresses tumor growth, prolongs animal survival, and exerts synergistic anti-tumor effects when combined with conventional chemotherapies in multiple preclinical NB models. This study identifies FA uptake as a critical metabolic dependency for MYCN-amplified tumors. Inhibiting FA uptake is an effective approach for improving current treatment regimens
Gas Accretion and Star Formation Rates
Cosmological numerical simulations of galaxy evolution show that accretion of
metal-poor gas from the cosmic web drives the star formation in galaxy disks.
Unfortunately, the observational support for this theoretical prediction is
still indirect, and modeling and analysis are required to identify hints as
actual signs of star-formation feeding from metal-poor gas accretion. Thus, a
meticulous interpretation of the observations is crucial, and this
observational review begins with a simple theoretical description of the
physical process and the key ingredients it involves, including the properties
of the accreted gas and of the star-formation that it induces. A number of
observations pointing out the connection between metal-poor gas accretion and
star-formation are analyzed, specifically, the short gas consumption time-scale
compared to the age of the stellar populations, the fundamental metallicity
relationship, the relationship between disk morphology and gas metallicity, the
existence of metallicity drops in starbursts of star-forming galaxies, the
so-called G dwarf problem, the existence of a minimum metallicity for the
star-forming gas in the local universe, the origin of the alpha-enhanced gas
forming stars in the local universe, the metallicity of the quiescent BCDs, and
the direct measurements of gas accretion onto galaxies. A final section
discusses intrinsic difficulties to obtain direct observational evidence, and
points out alternative observational pathways to further consolidate the
current ideas.Comment: Invited review to appear in Gas Accretion onto Galaxies, Astrophysics
and Space Science Library, eds. A. J. Fox & R. Dav\'e, to be published by
Springe
Star Formation Histories of the LEGUS Dwarf Galaxies (I): recent History of NGC1705, NGC4449 and Holmberg II
We use HST observations from the Legacy Extragalactic UV Survey to
reconstruct the recent star formation histories (SFHs) of three actively
star-forming dwarf galaxies, NGC4449, Holmberg II and NGC1705, from their UV
color-magnitude diagrams (CMDs). We apply a CMD fitting technique using two
independent sets of stellar isochrones, PARSEC-COLIBRI and MIST, to assess the
uncertainties related to stellar evolution modelling. Irrespective of the
adopted stellar models, all the three dwarfs are found to have had almost
constant star formation rates (SFRs) in the last 100-200 Myr, with modest
enhancements (a factor of 2) above the 100 Myr-averaged-SFR. Significant
differences among the three dwarfs are found in the overall SFR, the timing of
the most recent peak and the SFRarea. The Initial Mass Function (IMF) of
NGC1705 and Holmberg II is consistent with a Salpeter slope down to 5
M, whereas it is slightly flatter, s, in NGC4449. The SFHs
derived with the two different sets of stellar models are consistent with each
other, except for some quantitative details, attributable to their input
assumptions. They also share the drawback that all synthetic diagrams predict a
clear separation in color between upper main sequence and helium burning stars,
which is not apparent in the data. Since differential reddening, significant in
NGC4449, or unresolved binaries don't appear to be sufficient to fill the gap,
we suggest this calls for a revision of both sets of stellar evolutionary
tracks.Comment: 22 pages, 17 figures, accepted for publication on Ap
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