OntONeo: The Obstetric and Neonatal Ontology

This paper presents the Obstetric and Neonatal Ontology (OntONeo). This ontology has been created to provide a consensus representation of salient electronic health record (EHR) data and to serve interoperability of the associated data and information systems. More generally, it will serve interoperability of clinical and translational data, for example deriving from genomics disciplines and from clinical trials. Interoperability of EHR data is important to ensuring continuity of care during the prenatal and postnatal periods for both mother and child. As a strategy to advance such interoperability we use an approach based on ontological realism and on the ontology development principles of the Open Biomedical Ontologies Foundry, including reuse of reference ontologies wherever possible. We describe the structure and coverage domain of OntONeo and the process of creating and maintaining the ontology

Dealing with elements of medical encounters: An approach based on ontological realism

Electronic health records (EHRs) serve as repositories of documented data collected in a health care encounter. An EHR records information about who receives, who provides the health care and about the place where the encounter happens. We also observe additional elements relating to social relations in which the healthcare consumer is involved. To provide a consensus representation of common data and to enhance interoperability between different EHR repositories we have created a solution grounded in formal ontology. Here, we present how an ontology for the obstetric and neonatal domain deals with these general elements documented in health care encounters. Our goal is to promote the interoperability of information among EHRs created in different specialties. To develop our ontology, we used two main approaches: one based on ontological realism, the other based on the principles of the OBO Foundry, including reuse of reference ontologies

Computer-Aided Analysis of Formation Pressure Integrity Tests Used in Oil Well Drilling.

Formation pressure-integrity tests or leak-off tests have been increasingly performed throughout the world. The test is performed primarily to verify how much pressure can be applied to the formation below the bottom of casing, and to test the cement job sheath around the outside of the casing. The initial design of the various casing strings to be cemented in the well depends heavily on the predicted fracture-pressure curve. If this predicted curve is not verified by the test, the casing plan will have to be changed. Thus, verifying formation fracture-pressure during drilling is of great importance. However, the lack of a standard leak-off test procedure and standard interpretation technique for data analysis generally cause the results obtained by different well operators to vary significantly. In this study, the development of a computer simulation model for leak-off tests has been accomplished. This model is more realistic than the one currently used, but is sufficiently simple that it can be applied with data normally available during leak-off test operations in the field. The model includes the many factors that affect pressure behavior during the test, and can predict with reasonable accuracy what the pressure curve will look like. In addition, test interpretation using the computer model is easily achieved using a curve matching technique. The first step toward the development of the computer model was to subdivide the leak-off test into four phases: (1) pressure increase due to overall compressibility of the system, (2) fracture initiation, (3) fracture expansion, and (4) pressure decline and fracture closure after the pump is shut-in. The second step was the development of mathematical models for each phase separatedly. The mathematical model that predicts pressure increase before fracture initiation includes the most important variables affecting overall compressibility of the system. The modelling of fracture initiation is based on the classical elasticity theory. The modelling of fracture expansion and closure is based on the solution of the continuity equation for flow into a vertical-elliptical fracture with constant height. A computer program that predicts the pressure behavior during the leak-off test was written. This computer model was then verified using field data furnished by Tenneco Oil Company

Preordens regulares e indiferença comportamental

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Economia, Administração e Contabilidade, Departamento de Economia, Programa de Pós-Graduação em Economia, 2016.Nessa dissertação, são discutidos alguns aspectos dos fundamentos teóricos da escolha com preferências incompletas formulados por Eliaz e Ok (2006). Nosso objetivo é clarificar a condição de regularidade para preordens introduzida por esses autores, mostrando que ela não impõe nenhuma restrição se apenas estivermos interessados em racionalizar uma correspondência de escolha. Porém, se estivermos interessado em capturar outros aspectos observáveis do comportamento de escolha de um agente, por exemplo, a noção de c-incomparabilidade de Eliaz e Ok (2006) ou a noção de indiferença comportamental introduzida nesta dissertação, então a única opção é usar uma preordem regular. Argumentamos também que o Axioma Fraco da Não-Inferioridade Revelada (AFNIR) introduzido por Eliaz e Ok (2006) é muito forte se quisermos caracterizar a racionabilidade de uma correspondência de escolha por uma preordem possivelmente incompleta. Finalmente, como já foi mencionado acima, nós introduzimos a noção de indiferença comportamental e argumentamos que ela é mais geral do que a noção de Eliaz e Ok (2006) de c-incomparabilidade, sendo, ao mesmo tempo, complementar a esta dentro do framework dos autores.In this thesis, we discuss some aspects of Eliaz and Ok (2006)'s choice theoretical foundations of incomplete preferences. Our aim is to clarify their regularity condition for preorders, showing that, as far as rationalization of a choice correspondence alone is concerned, no further restriction is imposed by requiring the preorder to be regular. However, if one is also interested in capturing other observable aspects of the individual's choice procedure, such as Eliaz and Ok's notion of c-incomparability or the notion of behavioral indifference introduced in this paper, then the only option is to use a regular preorder. We also argue that their Weak Axiom of Revealed Non-inferiority (WARNI) is too strong a property if our aim is to characterize the rationalizability of a choice correspondence by a (possibly incomplete) preorder. Finally, as we have mentioned above, we introduce the notion of behavioral indifference and argue, not only that Eliaz and Ok's notion of c-incomparability (observable incomparability) can be derived from it, but also that it has a wider range of applicability than their notion of observable incomparability

The Blood Ontology: An ontology in the domain of hematology

Despite the importance of human blood to clinical practice and research, hematology and blood transfusion data remain scattered throughout a range of disparate sources. This lack of systematization concerning the use and definition of terms poses problems for physicians and biomedical professionals. We are introducing here the Blood Ontology, an ongoing initiative designed to serve as a controlled vocabulary for use in organizing information about blood. The paper describes the scope of the Blood Ontology, its stage of development and some of its anticipated uses

Application of kDNA as a molecular marker to analyse Leishmania infantum diversity in Portugal.

Around the Mediterranean basin Leishmania infantum is an important parasite causing canine leishmaniasis and visceral and cutaneous clinical forms in both immunocompetent and immunocompromised humans. Efficient monitoring and evaluation of epidemiology with discriminatory molecular markers are required. We investigated the genetic diversity of L. infantum in Portugal by polymerase chain amplification and restriction fragment length polymorphism analysis of kinetoplastid DNA, as molecular marker. We analysed 120 Portuguese isolates of L. infantum plus 16 other non-Portuguese isolates (as a reference group) from humans, dogs and sand flies. The Portuguese population showed a high degree of polymorphism with a total of 13 profiles identified. The predominant profile was A, which was only detected in the Portuguese samples. The kinetoplastid DNA PCR-RFLP assay described here was suitable for use directly with biological samples and the profiles obtained were stable during long-term growth in vitro and in laboratory animals

Tidal inlet migration and formation: the case of the Ararapira inlet – Brazil

The aim of this study is to assess the morphological evolution of the Ararapira (Brazil) barrier-inlet system, at different time scales. Based on satellite imagery, elevation data, and in-situ observations, we quantify the morphological evolution of the region. Results show that the Ararapira inlet migrated continuously southwards, moving updrift, with erosion at its southern margin and intercalated erosion and accretion at the northern margin. At approximately 5.5 km north of the old inlet, the gradual narrowing of the sandy barrier due to channel meandering and coastal erosion resulted in its breaching, in August 2018. We document the initial stages of the new inlet, which after opening, presents intense erosion at its southern margin, resulting in the channel widening to ~1 km. After the barrier breaches, the system begins to adjust to a new equilibrium condition, with the widening of the new inlet being balanced by the gradual closure of the old inlet. These drastic environmental changes control the functioning of such systems, and our results provide important background information for their use and management

CORRENTES COSTEIRAS E TRANSPORTE DE SEDIMENTOS NOS CANAIS DE NAVEGAÇÃO DO ESTUÁRIO DA BAÍA DE PARANAGUÁ

A variabilidade das correntes costeiras e a capacidade dessas correntes em transportar sedimentos por traçãoforam analisadas, na área externa do canal de acesso marítimo do Complexo Estuarino de Paranaguá, a partirde dados de dois fundeios do tipo L, localizados a aproximadamente 3,5 km da costa, e realizados entre os dias16/04/97 e 17/06/97. A dinâmica local, bem como o transporte dos sedimentos arenosos do fundo, é governadaprincipalmente pelas correntes de maré, as quais agem preferencialmente transversalmente à costa e no sentidocosta afora. Contudo, em situações de elevada energia, associadas à maior agitação do mar, a componentelongitudinal à costa ganha importância na circulação residual, intensificando o transporte de sedimentos em direção e ao longo da costa.The coastal currents variability and ability to carry sediment by bed load transport at the external area of thenavigation channel of Paranaguá’s estuary complex were analyzed from data obtained from two type L mooringslocated about 3.5 km from the coast, taken between 4/16/1997 and 6/17/1997. The local dynamics, as well asthe bottom transport of sandy sediments are ruled mainly by tidal currents which work mostly perpendicular andoutward from the coast. However, in a high energy situation associated to increased ocean wave energy, theparallel component to the coast gains prominence in the residual circulation, enhancing the sediment transport towards and along the coast