Automated software quality visualisation using fuzzy logic techniques

In the past decade there has been a concerted effort by the software industry to improve the quality of its products. This has led to the inception of various techniques with which to control and measure the process involved in software development. Methods like the Capability Maturity Model have introduced processes and strategies that require measurement in the form of software metrics. With the ever increasing number of software metrics being introduced by capability based processes, software development organisations are finding it more difficult to understand and interpret metric scores. This is particularly problematic for senior management and project managers where analysis of the actual data is not feasible. This paper proposes a method with which to visually represent metric scores so that managers can easily see how their organisation is performing relative to quality goals set for each type of metric. Acting primarily as a proof of concept and prototype, we suggest ways in which real customer needs can be translated into a feasible technical solution. The solution itself visualises metric scores in the form of a tree structure and utilises Fuzzy Logic techniques, XGMML, Web Services and the .NET Framework. Future work is proposed to extend the system from the prototype stage and to overcome a problem with the masking of poor scores

RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure

Selective gene silencing by RNA interference (RNAi) involves double-stranded small interfering RNA (ds siRNA) composed of single-stranded (ss) guide and passenger RNAs. siRNA is recognized and processed by Ago2 and C3PO, endonucleases of the RNA-induced silencing complex (RISC). RISC cleaves passenger RNA, exposing the guide RNA for base-pairing with its homologous mRNA target. Remarkably, the 3' end of passenger RNA can accommodate a DNA extension of 19-nucleotides without loss of RNAi function. This construct is termed passenger-3'-DNA/ds siRNA and includes a 3'-nuclease-resistant mini-hairpin structure. To test this novel modification further, we have now compared the following constructs: (I) guide-3'-DNA/ds siRNA, (II) passenger-3'-DNA/ds siRNA, (III) guide-3'-DNA/ss siRNA, and (IV) passenger-3'-DNA/ss siRNA. The RNAi target was SIRT1, a cancer-specific survival factor. Constructs I-III each induced selective knock-down of SIRT1 mRNA and protein in both noncancer and cancer cells, accompanied by apoptotic cell death in the cancer cells. Construct IV, which lacks the SIRT1 guide strand, had no effect. Importantly, the 3'-DNA mini-hairpin conferred nuclease resistance to constructs I and II. Resistance required the double-stranded RNA structure since single-stranded guide-3'-DNA/ss siRNA (construct III) was susceptible to serum nucleases with associated loss of RNAi activity. The potential applications of 3'-DNA/siRNA constructs are discussed. Molecular Therapy-Nucleic Acids (2014) 2, e141; doi:10.1038/mtna.2013.68; published online 7 January 2014

An investigation into the behaviour of air rifle pellets in ballistic gel and their interaction with bone

Although air weapons are considerably lower in power than other firearms, there is increasing concern that serious injuries can result from their misuse. The present study was therefore carried out to improve understanding of the terminal ballistic behaviour of air rifle pellets. Pellets were fired into ballistic gel under a variety of conditions. The pellets penetrated further than anticipated from their low cross-sectional density, and Bloom number was not necessarily a good guide to gel behaviour. Pellet penetration into the gel decreased with increasing gel concentration, and appeared to be linear at higher concentrations. Pointed pellets penetrated up to 50% further than rounded pellets. Power and range affect penetration, but other factors are also important, and power alone is not a simple guide to potential penetration. Test firings were also carried out firing pellets into ballistic gel that contained sections of animal bone. Computed tomography (CT) and visual observation were employed to record the interactions. CT scanning showed potential as a tool for examining pellet damage. The bone appeared to be undamaged, but the pellets were severely deformed on impact. If the pellet strikes the bone at an angle, less energy is absorbed by the impact and the pellet fragments may ricochet and cause further damage in the gel. A tentative model is proposed for estimating the energy absorbed by the impact

Stability of fluorescence of sodium salicylate

Sodium salicylate fluorescence stability over long periods of time - prevention of contamination by impuritie

Nondestructive ultrasonic measurement of bolt preload using the pulsed-phase locked-loop interferometer

Achieving accurate preload in threaded fasteners is an important and often critical problem which is encountered in nearly all sectors of government and industry. Conventional tensioning methods which rely on torque carry with them the disadvantage of requiring constant friction in the fastener in order to accurately correlate torque to preload. Since most of the applied torque typically overcomes friction rather than tensioning the fastener, small variations in friction can cause large variations in preload. An instrument called a pulsed phase locked loop interferometer, which was recently developed at NASA Langley, has found widespread use for measurement of stress as well as material properties. When used to measure bolt preload, this system detects changes in the fastener length and sound velocity which are independent of friction. The system is therefore capable of accurately establishing the correct change in bolt tension. This high resolution instrument has been used for precision measurement of preload in critical fasteners for numerous applications such as the space shuttle landing gear and helicopter main rotors

Subordination in Children’s Writing

This paper reports an investigation into the use of subordinate clauses in the writing of a class of seven to nine year old children when attempting five different writing tasks. The investigation was undertaken in part-response to an inspection report on the school by the Office for Standards in Education (Ofsted) which recommended that the school should extend the writing skills of pupils in this age-range. The importance of developing subordination in writing is related to previous research and to evidence from reviews of Ofsted inspection evidence. The different patterns of subordination are discussed, between tasks and pupils and in relation to variation in the writing of individual children when tackling the different tasks. The paper ends by suggesting how similar informal investigations can assist schools in promoting writing development. It also outlines how the teaching approaches outlined in the National Literacy Strategy will provide opportunities for this promotion, particularly by exploiting links between reading and writing

Design of a laminar-flow-control supercritical airfoil for a swept wing

An airfoil was analytically designed and analyzed for a combination of supercritical flow and laminar flow control (LFC) by boundary layer suction. A shockless inverse method was used to design an airfoil and an analysis method was used in lower surface redesign work. The laminar flow pressure distributions were computed without a boundary layer under the assumption that the laminar boundary layer would be kept thin by suction. Inviscid calculations showed that this 13.5 percent thick airfoil has shockless flows for conditions at and below the design normal Mach number of 0.73 and the design section lift coefficient of 0.60, and that the maximum local normal Mach number is 1.12 at the design point. The laminar boundary layer instabilities can be controlled with suction but the undercut leading edge of the airfoil provides a low velocity, constant pressure coefficients region which is conducive to laminar flow without suction. The airfoil was designed to be capable of lift recovery with no suction by the deflection of a small trailing edge flap

NATO: the view from the East

Relations between Russia, Ukraine and Belarus and NATO have placed more emphasis on cooperation than confrontation since the Cold War, and Ukraine has begun to move towards membership. At the popular level, on the evidence of national surveys in 2004 and 2005, NATO continues to be perceived as a significant threat, but in Russia and Ukraine it comes behind the United States (in Belarus the numbers are similar). There are few socioeconomic predictors of support for NATO membership that are significant across all three countries, but there are wide differences by region, and by attitudinal variables such as support for a market economy and for EU membership. The relationship between popular attitudes and foreign policy is normally a distant one; but in Ukraine NATO membership will require public support in a referendum, and in all three cases public attitudes on foreign policy issues can influence foreign policy in other ways, including the composition of parliamentary committees. In newly independent states whose international allegiances are still evolving, the associations between public opinion and foreign and security policy may often be closer than in the established democracies