White sorghum grain (Funk\u27s G766W) and elevator-run red sorghum grain compared for fattening cattle

An new white variety of sorghum grain (Funk\u27s G766W) has been reported to be higher in digestible dry matter and protein than elevator-run, rod sorghum grain. A 120-day field trial was conducted on the George and Vernon Miller farm near Great Bend to compare the two sorghum grain types under feed-lot conditions

Site and mechanism of enhanced gastrointestinal absorption of aluminum by citrate

Site and mechanism of enhanced gastrointestinal absorption of aluminum by citrate. Clinical and experimental studies have shown that citrate markedly enhances the intestinal absorption of aluminum (Al), but the site and mechanism of enhanced absorption are unknown. To determine where in the gastrointestinal tract aluminum citrate (Alcitr) was absorbed, Alcitr was gavaged with D-[1-3H] glucose in male Sprague-Dawley rats. Plasma Al levels increased rapidly and simultaneously peaked with D-[1-3G] glucose, suggesting early proximal bowel absorption. In in vitro duodenal and jejunal everted gut preparations, Alcitr incubation resulted in increased tissue Al levels and markedly enhanced transmural transport of Al and citr. Unlike citr, the transmural movement of Al was independent of temperature (37°C vs. 4°C). On the other hand, Al lactate (al Lac) increased tissue associated Al levels but had no effect on transmural Al movement. To determine if this large flux of Al following Alcitr administration was due to paracellular movement, ruthenium red and Ussing chamber studies were used to evaluate the morphologic and functional integrity of cellular tight junctions. Alcitr, as opposed to A1C13, markedly increased ruthenium red deposits in intercellular spaces, especially around goblet cells, and induced a prolonged significant reduction in transmural resistance. Alcitr also resulted in rapid and nearly complete (99.7%) chelation of free calcium, an event known to disrupt cellular tight junction integrity. Taken together, these data suggest that enhanced Al absorption following administration of Alcitr occurs in the proximal bowel via the paracellular pathway due to the opening of cellular tight junctions

Simple Fluids with Complex Phase Behavior

We find that a system of particles interacting through a simple isotropic potential with a softened core is able to exhibit a rich phase behavior including: a liquid-liquid phase transition in the supercooled phase, as has been suggested for water; a gas-liquid-liquid triple point; a freezing line with anomalous reentrant behavior. The essential ingredient leading to these features resides in that the potential investigated gives origin to two effective core radii.Comment: 7 pages including 3 eps figures + 1 jpeg figur

Non-LTE Treatment of Fe II in Astrophysical Plasmas

We describe our implementation of an extremely detailed model atom of singly ionized iron for NLTE computations in static and moving astrophysical plasmas. Our model atom includes 617 levels, 13675 primary permitted transitions and up to 1.2 million secondary transitions. Our approach guarantees that the total iron opacity is included at the correct wavelength with reasonable memory and CPU requirements. We find that the lines saturate the wavelength space, such that special wavelength points inserted along the detailed profile functions may be replaced with a statistical sampling method. We describe the results of various test calculations for novae and supernovae.Comment: 17 pages, latex, aip style, no figures included, full text with figures available at ftp://brian.la.asu.edu/pub/preprint/FeII-NLTE.ps.Z or at http://brian.la.asu.edu

On the Formation Height of the SDO/HMI Fe 6173 Doppler Signal

The Helioseismic and Magnetic Imager (HMI) onboard the Solar Dynamics Observatory (SDO) is designed to study oscillations and the mag- netic field in the solar photosphere. It observes the full solar disk in the Fe I absorption line at 6173\AA . We use the output of a high-resolution 3D, time- dependent, radiation-hydrodynamic simulation based on the CO5BOLD code to calculate profiles F({\lambda},x,y,t) for the Fe I 6173{\AA} line. The emerging profiles F({\lambda},x,y,t) are multiplied by a representative set of HMI filter transmission profiles R_i({\lambda},1 \leq i \leq 6) and filtergrams I_i(x,y,t;1 \leq i \leq 6) are constructed for six wavelengths. Doppler velocities V_HMI(x,y,t) are determined from these filtergrams using a simplified version of the HMI pipeline. The Doppler velocities are correlated with the original velocities in the simulated atmosphere. The cross- correlation peaks near 100 km, suggesting that the HMI Doppler velocity signal is formed rather low in the solar atmosphere. The same analysis is performed for the SOHO/MDI Ni I line at 6768\AA . The MDI Doppler signal is formed slightly higher at around 125 km. Taking into account the limited spatial resolution of the instruments, the apparent formation height of both the HMI and MDI Doppler signal increases by 40 to 50 km. We also study how uncertainties in the HMI filter-transmission profiles affect the calculated velocities.Comment: 15 pages, 11 Figure

Parallelization of the discrete gradient method of non-smooth optimization and its applications

We investigate parallelization and performance of the discrete gradient method of nonsmooth optimization. This derivative free method is shown to be an effective optimization tool, able to skip many shallow local minima of nonconvex nondifferentiable objective functions. Although this is a sequential iterative method, we were able to parallelize critical steps of the algorithm, and this lead to a significant improvement in performance on multiprocessor computer clusters. We applied this method to a difficult polyatomic clusters problem in computational chemistry, and found this method to outperform other algorithms. <br /

Differential geometry construction of anomalies and topological invariants in various dimensions

In the model of extended non-Abelian tensor gauge fields we have found new metric-independent densities: the exact (2n+3)-forms and their secondary characteristics, the (2n+2)-forms as well as the exact 6n-forms and the corresponding secondary (6n-1)-forms. These forms are the analogs of the Pontryagin densities: the exact 2n-forms and Chern-Simons secondary characteristics, the (2n-1)-forms. The (2n+3)- and 6n-forms are gauge invariant densities, while the (2n+2)- and (6n-1)-forms transform non-trivially under gauge transformations, that we compare with the corresponding transformations of the Chern-Simons secondary characteristics. This construction allows to identify new potential gauge anomalies in various dimensions.Comment: 27 pages, references added, matches published versio

Phenomenological Tests of Supersymmetric A_4 Family Symmetry Model of Neutrino Mass

Recently Babu, Ma and Valle proposed a model of quark and lepton mixing based on $A_4$ symmetry. Within this model the lepton and slepton mixings are intimately related. We perform a numerical study in order to derive the slepton masses and mixings in agreement with present data from neutrino physics. We show that, starting from three-fold degeneracy of the neutrino masses at a high energy scale, a viable low energy neutrino mass matrix can indeed be obtained in agreement with constraints on lepton flavour violating $\mu$ and $\tau$ decays. The resulting slepton spectrum must necessarily include at least one mass below 200 GeV which can be produced at the LHC. The predictions for the absolute Majorana neutrino mass scale $m_0 \geq 0.3$ eV ensure that the model will be tested by future cosmological tests and $\beta\beta_{0\nu}$ searches. Rates for lepton flavour violating processes $\ell_j \to \ell_i + \gamma$ in the range of sensitivity of current experiments are typical in the model, with BR(\mu \to e \gamma) \gsim 10^{-15} and the lower bound BR$(\tau \to \mu \gamma) > 10^{-9}$. To first approximation, the model leads to maximal leptonic CP violation in neutrino oscillations.Comment: 23 pages, 7 figure

Defining a spinal microcircuit that gates myelinated afferent input: implications for tactile allodynia

Chronic pain presents a major unmet clinical problem. The development of more effective treatments is hindered by our limited understanding of the neuronal circuits underlying sensory perception. Here, we show that parvalbumin (PV)-expressing dorsal horn interneurons modulate the passage of sensory information conveyed by low-threshold mechanoreceptors (LTMRs) directly via presynaptic inhibition and also gate the polysynaptic relay of LTMR input to pain circuits by inhibiting lamina II excitatory interneurons whose axons project into lamina I. We show changes in the functional properties of these PV interneurons following peripheral nerve injury and that silencing these cells unmasks a circuit that allows innocuous touch inputs to activate pain circuits by increasing network activity in laminae I–IV. Such changes are likely to result in the development of tactile allodynia and could be targeted for more effective treatment of mechanical pain