13 research outputs found
Composition of dental plaque formed in the presence of sucrose and after its interruption
- Author
- Publication venue
- Fundação Odontológica de Ribeirão Preto
- Publication date
- 01/01/2003
- Field of study
Since dental plaque reservoirs of fluoride (F), calcium (Ca) and inorganic phosphorus (Pi) are susceptible to decreases in pH, this in situ crossover study was conducted to test the hypothesis that the low concentration of these ions in plaque, formed in the presence of sucrose, could be attributed merely to the fermentation of this sugar. Eleven volunteers wore palatal appliances containing 6 human enamel blocks during two stages. In each stage, the treatments were either 20% sucrose solution or distilled deionized water, which were dripped onto the blocks 8 times a day. After 28 days, in each stage, the dental plaque formed on two blocks was collected, the treatment was inverted and after a further 24 and 48 h, the biofilm formed was collected from the other blocks. The concentration of acid-soluble F, Ca and Pi, and the concentration of insoluble polysaccharide (IP) were determined in the dental plaque. Statistically lower concentrations of F, Ca and Pi, and a higher concentration of IP were found in the 28-day biofilm formed in the presence of sucrose than in its absence; after the treatment inversion the change in F, Ca and Pi was not statistically significant, but the IP concentration changed significantly. The hypothesis was rejected because change in concentration of F, Ca and Pi is not due to fermentation of the sucrose
Composition of dental plaque formed in the presence of sucrose and after its interruption
- Author
- Publication venue
- Fundação Odontológica de Ribeirão Preto
- Publication date
- Field of study
Since dental plaque reservoirs of fluoride (F), calcium (Ca) and inorganic phosphorus (Pi) are susceptible to decreases in pH, this in situ crossover study was conducted to test the hypothesis that the low concentration of these ions in plaque, formed in the presence of sucrose, could be attributed merely to the fermentation of this sugar. Eleven volunteers wore palatal appliances containing 6 human enamel blocks during two stages. In each stage, the treatments were either 20% sucrose solution or distilled deionized water, which were dripped onto the blocks 8 times a day. After 28 days, in each stage, the dental plaque formed on two blocks was collected, the treatment was inverted and after a further 24 and 48 h, the biofilm formed was collected from the other blocks. The concentration of acid-soluble F, Ca and Pi, and the concentration of insoluble polysaccharide (IP) were determined in the dental plaque. Statistically lower concentrations of F, Ca and Pi, and a higher concentration of IP were found in the 28-day biofilm formed in the presence of sucrose than in its absence; after the treatment inversion the change in F, Ca and Pi was not statistically significant, but the IP concentration changed significantly. The hypothesis was rejected because change in concentration of F, Ca and Pi is not due to fermentation of the sucrose.Desde que os reservatĂłrios de flĂșor (F), cĂĄlcio (Ca) e fĂłsforo inorgĂąnico (Pi) na placa dental sĂŁo suscetĂveis a quedas de pH, este estudo in situ cruzado foi conduzido para testar a hipĂłtese de que baixas concentraçÔes destes Ăons na placa, formada na presença de sacarose, poderiam ser atribuĂdas simplesmente Ă fermentação deste açĂșcar. Onze voluntĂĄrios utilizaram dispositivos palatinos contendo seis blocos de esmalte dental humano durante duas fases. Em cada fase os tratamentos foram solução de sacarose a 20% ou ĂĄgua destilada deionizada, que foram gotejadas sobre os blocos 8 vezes ao dia. ApĂłs 28 dias, em cada fase, a placa dental formada sobre dois blocos foi coletada, o tratamento foi invertido e apĂłs um tempo adicional de 24 e 48 horas, o biofilme formado foi coletado dos outros blocos. A concentração de F, Ca e Pi solĂșvel em ĂĄcido e a concentração de polissacarĂdeo insolĂșvel (PI) foram determinadas na placa dental. ConcentraçÔes estatisticamente menores de F, Ca e Pi, e uma concentração maior de PI foram encontradas no biofilme de 28 dias formado na presença de sacarose do que na sua ausĂȘncia; apĂłs a inversĂŁo do tratamento a mudança no F, Ca e Pi nĂŁo foi estatisticamente significante, mas a concentração de PI mudou significativamente. A hipĂłtese foi rejeitada porque a mudança na concentração de F, Ca e Pi nĂŁo Ă© devida Ă fermentação da sacarose.147152Conselho Nacional de Desenvolvimento CientĂfico e TecnolĂłgico (CNPq
Composition of dental plaque formed in the presence of sucrose and after its interruption
- Author
- Publication venue
- Fundação Odontológica de Ribeirão Preto
- Publication date
- Field of study
Since dental plaque reservoirs of fluoride (F), calcium (Ca) and inorganic phosphorus (Pi) are susceptible to decreases in pH, this in situ crossover study was conducted to test the hypothesis that the low concentration of these ions in plaque, formed in the presence of sucrose, could be attributed merely to the fermentation of this sugar. Eleven volunteers wore palatal appliances containing 6 human enamel blocks during two stages. In each stage, the treatments were either 20% sucrose solution or distilled deionized water, which were dripped onto the blocks 8 times a day. After 28 days, in each stage, the dental plaque formed on two blocks was collected, the treatment was inverted and after a further 24 and 48 h, the biofilm formed was collected from the other blocks. The concentration of acid-soluble F, Ca and Pi, and the concentration of insoluble polysaccharide (IP) were determined in the dental plaque. Statistically lower concentrations of F, Ca and Pi, and a higher concentration of IP were found in the 28-day biofilm formed in the presence of sucrose than in its absence; after the treatment inversion the change in F, Ca and Pi was not statistically significant, but the IP concentration changed significantly. The hypothesis was rejected because change in concentration of F, Ca and Pi is not due to fermentation of the sucrose
Composition of dental plaque formed in the presence of sucrose and after its interruption
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2003
- Field of study
NĂșcleos de Ensino da Unesp: artigos 2013: volume 2: metodologias de ensino e a apropriação de conhecimento pelos alunos
- Author
- Colvara Laurence Duarte
- Oliveira José Brås Barreto de
- Tosi Pedro Geraldo Saadi
- Celestino Willena de Jesus Bispo
- Barbosa Maria Valéria
- Carvalho Marcus VinĂcius de Souza Perez de
- Rosa Ana Paula
- Fenerick José Adriano
- Lopes Diego dos Santos Ferrari
- Salles Octavio Francioso
- Ruiz Renan Branco
- Castro Rosane Michelli de
- Lima Elieuza Aparecida de
- Ribeiro Aline Escobar MagalhĂŁes
- Silva Nelson Pedro da
- Belluci Aline Marques
- Tommaselli José Tadeu Garcia
- Roxinol ClĂĄudia Dias
- Giroto Daiane Barbosa
- Nobre Silvania Lanfredi
- Prado Denize Francisco do
- Nobre Marcos Augusto de Lima
- Santos Marcilene dos
- Carvalhal Marcelo Dornelis
- Fuini Lucas Labigalini
- Schiavon Laurita Marconi
- Roveri Paulo
- Porto Jaqueline
- Lima LetĂcia Bartholomeu de Queiroz
- Deutsch Silvia
- Paulo Rosa Monteiro
- Mondini Fabiane
- Souza Antonio Carlos de
- Viotto Filho Irineu Aliprando Tuim
- Ponce Rosiane de FĂĄtima
- Felix Tatiane da Silva Pires
- Nunes Rodrigo Lima
- Santos Ariana Aparecida Nascimento dos
- Bezerra Janaina Pereira Duarte
- Fracon Thais Lima
- Ponce Guilherme Lopes
- Pereira Caroline Galan de Souza
- Antonio Larissa Zangarini
- Silva Camila Rocha e
- Miura Regina Keiko Kato
- Yassuda Ariane Seiko Kubo
- Spazziani Maria de Lourdes
- Vieira Jonas da Costa
- Cunha Victor Ferreira da
- Rodrigues José de Souza
- Scarelli Ariane
- Zambon KĂĄtia LĂvia
- Marinho Mariana de Toledo
- Dornfeld Carolina Buso
- Santos Elisa Maria dos
- Loretto JĂ©ssica Arantes
- Cardozo Bruna Santos
- Garves José Daniel Soler
- Silva Bruna Vargas Rocha da
- Menezes NatĂĄlia Pires
- Souza Renata Junqueira de
- Santos Ana Laura Garro dos
- Oittica Cristine Reis
- Martins Neto Irando Alves
- Batista Josany Leme da Silva
- Vagula Vania Kelen BelĂŁo
- Souza Tatiana Noronha de
- Cavalari Karina Freitas
- Urbinati Eliza
- Maia Diego CorrĂȘa
- Christofoletti Anderson Luis Hebling
- Silva MĂĄrcia Pereira da
- Moura Monique
- Mello MĂĄrcia Cristina de Oliveira
- Domiciano Douglas
- Spinelli Juliana Andrade
- Veiga-Santos Pricila
- Vali Larissa Oliveira
- Leme Luiz Renato Fukumoto
- Ito Claudemira Azevedo
- Matthiesen Sara Quenzer
- Macedo Thiago Padovan
- Ginciene Guy
- Passini Gabriel Katayama
- Zuluaga Carlos Federico Ayala
- Seraphim Marina Pires
- Conte Denis Rodrigo Del
- Mello Guilherme Oleinik de
- Camuci Guilherme CorrĂȘa
- Oliveira Bruna Feitosa de
- Scopinho Renan Heli Vales
- Sousa HilĂĄrio Francisco de
- Perusi Maria Cristina
- Gomes Junior Estevão Conceição
- Kodama Katia Maria Roberto de Oliveira
- Nunes JoĂŁo Osvaldo Rodrigues
- Nascimento Ribas Dantas do
- Verissimo Victor Emmamuel Albertin
- Publication venue
- Cultura AcadĂȘmica
- Publication date
- 01/01/2015
- Field of study
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP
NĂșcleos de Ensino da Unesp: artigos 2013: volume 2: metodologias de ensino e a apropriação de conhecimento pelos alunos
- Author
- Antonio Larissa Zangarini
- Barbosa Maria Valéria
- Batista Josany Leme da Silva
- Belluci Aline Marques
- Bezerra Janaina Pereira Duarte
- Camuci Guilherme CorrĂȘa
- Cardozo Bruna Santos
- Carvalhal Marcelo Dornelis
- Carvalho Marcus VinĂcius de Souza Perez de
- Castro Rosane Michelli de
- Cavalari Karina Freitas
- Celestino Willena de Jesus Bispo
- Christofoletti Anderson Luis Hebling
- Colvara Laurence Duarte
- Conte Denis Rodrigo Del
- Cunha Victor Ferreira da
- Deutsch Silvia
- Domiciano Douglas
- Dornfeld Carolina Buso
- Felix Tatiane da Silva Pires
- Fenerick José Adriano
- Fracon Thais Lima
- Fuini Lucas Labigalini
- Garves José Daniel Soler
- Ginciene Guy
- Giroto Daiane Barbosa
- Gomes Junior Estevão Conceição
- Ito Claudemira Azevedo
- Kodama Katia Maria Roberto de Oliveira
- Leme Luiz Renato Fukumoto
- Lima Elieuza Aparecida de
- Lima LetĂcia Bartholomeu de Queiroz
- Lopes Diego dos Santos Ferrari
- Loretto JĂ©ssica Arantes
- Macedo Thiago Padovan
- Maia Diego CorrĂȘa
- Marinho Mariana de Toledo
- Martins Neto Irando Alves
- Matthiesen Sara Quenzer
- Mello Guilherme Oleinik de
- Mello MĂĄrcia Cristina de Oliveira
- Menezes NatĂĄlia Pires
- Miura Regina Keiko Kato
- Mondini Fabiane
- Moura Monique
- Nascimento Ribas Dantas do
- Nobre Marcos Augusto de Lima
- Nobre Silvania Lanfredi
- Nunes JoĂŁo Osvaldo Rodrigues
- Nunes Rodrigo Lima
- Oittica Cristine Reis
- Oliveira Bruna Feitosa de
- Oliveira José Brås Barreto de
- Passini Gabriel Katayama
- Paulo Rosa Monteiro
- Pereira Caroline Galan de Souza
- Perusi Maria Cristina
- Ponce Guilherme Lopes
- Ponce Rosiane de FĂĄtima
- Porto Jaqueline
- Prado Denize Francisco do
- Ribeiro Aline Escobar MagalhĂŁes
- Rodrigues José de Souza
- Rosa Ana Paula
- Roveri Paulo
- Roxinol ClĂĄudia Dias
- Ruiz Renan Branco
- Salles Octavio Francioso
- Santos Ana Laura Garro dos
- Santos Ariana Aparecida Nascimento dos
- Santos Elisa Maria dos
- Santos Marcilene dos
- Scarelli Ariane
- Schiavon Laurita Marconi
- Scopinho Renan Heli Vales
- Seraphim Marina Pires
- Silva Bruna Vargas Rocha da
- Silva Camila Rocha e
- Silva MĂĄrcia Pereira da
- Silva Nelson Pedro da
- Sousa HilĂĄrio Francisco de
- Souza Antonio Carlos de
- Souza Renata Junqueira de
- Souza Tatiana Noronha de
- Spazziani Maria de Lourdes
- Spinelli Juliana Andrade
- Tommaselli José Tadeu Garcia
- Tosi Pedro Geraldo Saadi
- Urbinati Eliza
- Vagula Vania Kelen BelĂŁo
- Vali Larissa Oliveira
- Veiga-Santos Pricila
- Verissimo Victor Emmamuel Albertin
- Vieira Jonas da Costa
- Viotto Filho Irineu Aliprando Tuim
- Yassuda Ariane Seiko Kubo
- Zambon KĂĄtia LĂvia
- Zuluaga Carlos Federico Ayala
- Publication venue
- Cultura AcadĂȘmica
- Publication date
- Field of study
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP
NĂșcleos de Ensino da Unesp: artigos 2009
- Author
- Achcar Karina
- Aguiar Mayra Costa
- Akamatsu JĂąnio Itiro
- Alaniz Erika Porceli
- Albuquerque Denise Ivana de Paula
- Almeida Vera Lia Marcondes Criscuolo de
- Alvarado Thiago Henrique
- Alves Maria José Queiroz de Freitas
- Ameduri Talita Sousa
- Amorim Carlos Eduardo Silva da
- Américo Fernanda Galvão
- Andrade Lizbeth Oliveira de
- Annibal SĂ©rgio Fabiano
- Araujo Andréa Mendez
- Araujo Lilian Aparecida de
- Araya Ana Maria OsĂłrio
- Archanjo Naiara Carolina Pereira
- Arnoni Maria Eliza Brefere
- Arruda Daniele Vaz de
- Arruda Olavo Speranza de
- Assis Alice
- Augusto ThaĂs Gimenez da Silva
- Azambuja LaĂs Rosa Souza
- Azevedo TĂąnia Cristina Arantes Macedo de
- Baleotti Luciana Ramos
- Barbosa Luciane Maria Molina
- Barbosa Maria Valéria
- Barbosa Raquel Lazzari Leite Barbosa
- Barreiro IraĂde Marques de Freitas
- Barrezzi Karina
- Barros Mariana Costa Beltran de
- Batista Renata F. M.
- Beraldi Francielle Bonfim
- Bezerra Graziela Leite
- Bicudo Luiz Roberto Hernandes
- Bilato Carolina
- Birolli Marcela Fernanda Val
- Bittencourt Pedro Gabriel Pompermayer Leite
- Boaro Sueli Nicolau
- Boaventura André Luis
- Bochorny Jucileny
- Bofi TĂąnia Cristina
- Brabo TĂąnia Suely Antonelli Marcelino
- Braguin MĂĄrcio Luiz
- BrandĂŁo EvinĂĄria
- Brettas Julia Horesh
- Brito Iara Aparecida de Oliveira
- Bronzato JoĂŁo Felipe
- Bueno Fagner Leandro
- Burato Giovana
- Cabrera MĂŽnica Almeida
- Caetano Aline de Souza
- Caface Raphael Antonio
- Calsavara MariĂąngela Alves de MagalhĂŁes
- Camargo Paulo SĂ©rgio Camillo de
- Campos Luciana Maria Lunardi
- Capodeferro Breno Cacossi
- Cardia Elizabeth Mattiazzo
- Cardoso Celso Xavier
- Carré Gabriela Machado
- Carvalho Augusto Cesinando de
- Carvalho Fernando Luiz de Campos
- Carvalho Thiago Henrique de
- Casarin Helen de Castro Silva
- Castro Natiane Bonani Lopes de
- Castro Rosane Michelli de
- Cattai Maria Dirlene da Silva
- CesĂĄrio Maria Dalva
- Chaves Amanda Pires
- Cirqueira Samirys Sara Rodrigues
- Conceição Jéssica Grava da
- Consolari Ana ClĂĄudia
- Constantino Elizabeth Piemonte
- Cordeiro Ana Paula
- Cordeiro Maria Angela de Moraes
- Corneto Nathalia
- CorrĂȘa Roberta GuimarĂŁes
- Costa Dora Isabel Paiva da
- Costa Gabriel Rodrigues
- Costa Paulo Ricardo Mendes da
- Costa Renata Correia
- Cravo Haroldo de Lima Pimentel
- CristĂłvĂŁo Manuela Aparecida Marini
- Cruz Luciana Aparecida Nogueira da
- Cruz Luiz Francisco da
- Cruz Maria de Lourdes Otero Brabo
- Cypriano Vivian Tiemi Hamamoto
- CĂĄceres Isabel Cristina Briones
- CĂĄceres Lucas Braghetta
- Damaceno Airton Juliano
- Daniel Juliana Cardoso
- Dantas Denise JerĂŽnimo
- Darido Suraya Cristina
- Davalos Marian Rosaly
- David CĂ©lia Maria
- Deliberato DĂ©bora
- Djanira Soares de Oliveira e Almeida
- Dornfeld Carolina Buso
- Drigo Filho Elso
- Duarte ThaĂs
- Encarnação Gislaine Aparecida Alves da
- Evangelista Luis Antonio
- Faccio Neide Barroca
- Fachin Maria Celeste
- Fagundes Gustavo Henrique Godoy
- Fanti ErmĂnia de Lourdes Campello
- Feitosa Eloi
- Feitoza NatĂĄlia Vechiatto
- Fekete Dominique
- Felix Tatiane da Silva Pires
- Fernandes Iveta Maria Borges Ăvila
- Ferraz ClĂĄudio Benito Oliveira
- Ferreira Aline Fernanda
- Ferreira LĂlian Aparecida
- Ferreira LĂlian Aparecida
- Ferreira Philipe Andrade
- Fertonani Fernando Luis
- Fertonani IĂȘda Aparecida Pastre
- Figueiredo PĂąmela Buzanello
- Fossaluza André Santachiara
- Fragoso Neto Raul Antonio
- Fraiha Ana LĂvia Gorgatto
- Franceschini Lilia Guerrero
- Franco Jacqueline Oshima
- Freitas Fernando Paulo Rosa de
- Freitas Talita Graciara
- Freitas Zulind Luzmarina
- FĂŒrkotter Monica
- Galvanese Isadora Soares
- Garcia MĂĄrcia SĂlvia
- Gazola Rodrigo José Cristiano
- Gazzoli Francini
- Gelamos JoĂŁo Paulo
- Geraldo Willian Bala
- Giometti AnalĂșcia Bueno dos Reis
- Giorgi Cristiano Amaral Garboggini Di
- Giroto Claudia Regina Mosca
- Girotto Cyntia Graziella Guizelim SimÔes
- Giuliani Thais Saes
- Godoy Claraline Stocco de
- Goes André Thiago Rossito
- Gonçalves Abgail Brito
- GouvĂȘa Evaldo Chagas
- Granato Guilherme
- Granville Maria Antonia
- Grosseli Marcela Martins
- Guarizi Mario Roberto
- Haga Kuniko Iwamoto
- Haga Mario Susumo
- Henrique Leonardo Fernandes
- Humberto LetĂcia
- Hunger Dagmar
- Iasi ThaynĂĄ Cristina Parsaneze
- Inforsato Ana Paula
- Inforsato Edson de Carmo
- Ito Claudemira Azevedo
- Jango Aline Agnelo
- Januårio André Alves
- Jorge Juliana
- JĂłdas Mariana Beolchi
- Kamimura MĂĄrcio Kazuhiko
- Kasseboehmer Ana ClĂĄudia
- Klassa Bruna
- Lamas Rita de CĂĄssia Pavani
- Leite LĂșcia Pereira
- Leite Yoshie Ussami Ferrari
- Leme Anna Paola Torrizi
- Lemes Thaiz Negrizolli
- Lima Carlos Henrique Ferreira Sholl de Freitas
- Lima Elieuza Aparecida de
- Lima José Milton de
- Lima Junior Carlos Henrique Santos
- Lima Maria Fernanda Rodrigues de
- Lima MĂĄrcia Regina Canhoto de
- Lima Vanda Moreira Machado
- Lino Alex
- Longhitano Gabriel Augusto
- Lopes Eloisa Assunção de Melo
- Lopes José Marcos
- Lopes Rosemara Perpetua
- Lotufo JoĂŁo Paulo Becker Junior
- Ludvério Douglas Jovino
- Luppi Eduardo da Costa
- Luz Juliana Aparecida Rocha
- Machado Jaqueline Cristine
- Machado Thiago Augusto de Freitas
- Magoga Juliana de Carvalho
- Malheiro Taiane de O.
- Maltoni KĂĄtia Luciene
- Manoel Ivan Aparecido
- Marin FĂĄtima Aparecida Dias Gomes
- Marques Emilia de Mendonça Rosa
- Marques Rosebelly Nunes
- Martineli Ana CĂ©lia Carlin
- Martino VĂąnia de FĂĄtima
- Martins Bruna Tadeusa Genaro
- Martins Deise Soares
- Martins Demétrius Lira
- Martins Raul AragĂŁo
- Martins Sandra Eli Sartoreto
- Martins Willian Henrique
- Matheus Selma Maria Michelin
- Matthiesen Sara Quenzer
- Mazotti Adriano CĂ©sar
- Medeiros LetĂcia Thais
- Mello Denise Fernandes de
- Mello MĂĄrcia Cristina de Oliveira
- Melo Fernanda Passarini
- Mendes Carolina Borghi
- Mendonça Sueli Guadelupe de Lima
- Miguel José Carlos
- Minoti Aline Pereira
- Molero Camila Schimite
- Montebello PatrĂcia Rosada
- Monteiro Isabel Cristina de Castro
- Monteiro Marco Aurélio Alvarenga
- Monteiro Mauricio
- Monteiro Suelen Santos
- Moraes Ana Paula Pacheco
- Moraes Mara Sueli SimĂŁo
- Moreira Tony Aparecido
- Morelatti Maria Raquel Miotto
- Moulatlet Gabriel Massaine
- Moura Amanda Christina Gomes de
- Moura Gabriella Garcia
- Mouro Bruna Carolina
- MĂ©rcuri Ricardo Luis
- Nascimento Mayara C. J.
- Nascimento VerĂŽnica Maria do
- Nigro ClĂĄudia Maria Ceneviva
- Nobre Marcos Augusto de Lima
- Nobre Silvania Lanfredi
- Nogueira Talita Cristina Leal
- Nomura Douglas Mamoru
- Nono Maévi Anabel
- Nunes Felipe Barros
- Nunes JoĂŁo Osvaldo Rodrigues
- Nunes Rodrigo Lima
- Obst OtĂlia Nair
- Oishi Sissy Bianca Maia
- Oliveira Amanda de Carvalho Maia
- Oliveira Ana Ligia Santos de
- Oliveira Ernandes Rocha de
- Oliveira Joana Cristina de Souza
- Oliveira José Brås Barreto de
- Oliveira Leila de
- Oliveira Natalia Zulmira Massuqueti de
- Oliveira Rosemary Rodrigues de
- Oliveira Yuri Alves de
- Oluwatuyi Folashade Airam Olufunke
- Orlandi Leonardo de Ăngelo
- Ortiz Camila Aparecida
- Ozaki Guilherme Tamura
- Paleari Lucia Maria
- Paula Douglas Gonçalves de
- Paula Paulo Ricardo Villa de
- Pavezi NatĂĄlia Prioto
- Pelegrini Anderson de Oliveira
- Penteado Miriam Godoy
- Pereira Aline Natasha
- Pereira LĂąnia Auxiliadora
- Pereira Priscila
- Peretto Karine Inae Moreira
- Perusi Maria Cristina
- Peruzzi Nelson José
- Peverani Camila Rizzardi
- Peña Angel Fidel Fiche
- Pianoschi Thaisa Alves
- Pimenta Juliana Carla Fleiria
- Pinho Sheila Zambello de
- Pino Larissa JordĂŁo
- Pinto Renan Mercuri
- Pires Ana Maria
- Pires Iana da Costa
- Pitta Francieli Major
- Plicas LĂdia Maria de Almeida
- Pommella Amanda Carolina Freire
- Ponce Rosiane de FĂĄtima
- Pontes Evelise Raquel de
- Prado Denize Francisco do
- Prates Kamila EugĂȘnia Pavarina
- Prates Renata Pereira
- Premuli LaĂz Mariana Rosa
- Reis Larissa Menezes dos
- Reis Maria Augusta Machado
- Ribeiro PatrĂcia Vieira
- Risso Luciene Cristina
- Rocha Elizabete Sanches
- Rocha Paulo CĂ©sar
- Rodrigues Jean Cesar
- Rogone Heloisa Maria HeradĂŁo
- Romualdo Alisson Lucas
- Roque Araguaia Solange de Souza
- Rosa Erica Aparecida Capasio
- Rossi Fernanda
- Rufini Gabriel Barbieri
- Rufino Luiz Gustavo Bonatto
- Saad Ricardo Wurthmann
- Sabino Marilei Amadeu
- Salmazo Leandra Oliveira
- Sameshima Fabiana Sayuri
- Sampaio Ana Carolina
- Santana Jane Aparecida de Souza
- Santanna Bruna Bertasso
- Santos Amanda Sertori dos
- Santos Bruno Garcia dos
- Santos Bruno Rodrigo dos
- Santos Danielle Aparecida do Nascimento dos
- Santos Gislaine Aredes Soares dos
- Santos Henrique da Silva
- Santos JanaĂna Hellen Lima
- Santos Larissa Aparecida Trindade dos
- Santos Maria de FĂĄtima de Castro Lacaz
- Santos Matheus Tabata
- Santos Talita de Mello
- Santos ThaĂs Yuri JĂŽ
- Santos Tiago Martins dos
- Santos VinĂcius Martins dos
- Saracino Evandro Rafael
- Sarmento Graziela
- Sato Luciane Missae
- SchlĂŒnzen Elisa Tomoe Moriya
- Schubert Marcelo Dobrovolsky
- Sena Carla Cristina Reinaldo Gimenes de
- Sena Galeno José de
- Sibila Camila Basso
- Silva Junior Marcos Roberto Moreira da
- Silva Amanda Pimentel da
- Silva Bruna Tairine
- Silva Bruno Ricardo Machado da
- Silva Caio Samuel Franciscati da
- Silva Camila S. da
- Silva Elisandra Carla da
- Silva FĂĄbio Esteves da
- Silva Gabriela Dias da
- Silva Irma Dutra Gomes de Oliveira e
- Silva Izabella Alvarenga
- Silva Josiane Katsue Savay da
- Silva José Humberto Dias da
- Silva JoĂŁo Ricardo Neves da
- Silva JĂ©ssica de Lima
- Silva Lucas JĂșnior Pereira da
- Silva Lucilene Fernanda da
- Silva Luiz Guilherme Lucildo da
- Silva LĂșcia Helena de Oliveira
- Silva Marcelo C. da
- Silva MĂĄrcia Pereira da
- Silva Naiara Martins
- Silva Roberto Tiago Correa
- Silva Sabrina de Melo Correia da
- Silva Talita Fabiana Roque da
- Silva VandeĂ Pinto da
- Silva Viviane A. A. da
- Silva Wellington Domingos Pereira da
- Silva Wilton Carlos Lima da
- Silveira Ana Terra Camilo
- Soler Aline Shaaban
- Sonsim Priscila Rodrigues
- Souza JĂșnior Everton LuĂs de
- Souza AnalĂșcia Castro Pimenta da
- Souza FĂĄbio Marques de
- Souza Gabriela Reginato de
- Souza Hellen Cristiane de
- Souza Natalya Camargo de
- Souza Renata Junqueira de
- Spazziani Maria de Lourdes
- SĂĄenz Carlos Alberto Tello
- Sörensen Sheiva
- Talamoni Jandira Liria Biscalquini
- Tamanaha Andreza
- Teixeira Marcos Fernando de Souza
- Teixeira Paulo Eduardo
- Thesbita Lucinda Bittencourt
- Tiera Mårcio José
- Tiera Vera Aparecida de Oliveira
- Tommaselli José Tadeu Garcia
- Toyohara Doroti Quiomi Kanashiro
- Valezi Jokasta Aparecida
- Varalta Najla
- Velden Helena Ferreira Vander
- Vieira Noemia Ramos
- Villela FĂĄbio Camargo Bandeira
- Viotto Filho Irineu Aliprando Tuim
- Vollet Fernanda
- Whitaker Marisa Andreata
- Wiezzel Andréia Cristiane Silva
- Wolf FlĂĄvia Cristina
- Xavier Leiliane Ferraz
- Xavier Paula Martins
- Zacharias Andréa Aparecida
- Zaher Camila Al
- Zandonaidi JĂșlio CĂ©sar
- Zeni Ana Carla
- Zuliani Silvia Regina Quijadas Aro
- Publication venue
- Pró-Reitoria de Graduação (PROGRAD UNESP)
- Publication date
- Field of study
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
- Author
- Abad Jorge
- Abel Laurent
- Abel Laurent
- Abel Laurent
- Abel Laurent
- Accordino Giulia
- Achille Cristian
- Acosta-Ampudia Yeny
- Agra Juan José Cåceres
- Aguilera-Albesa Sergio
- AguilĂł-Cucurull Aina
- Aiuti Alessandro
- Aiuti Alessandro
- Aiuti Alessandro
- Akcan Ăzge Metin
- Al-Muhsen Saleh
- Al-Mulla Fahd
- Alavoine Loubna
- Albert Matthew
- Albisures Jonathan Antonio Roblero
- Alcover Andres
- Aldave Juan
- Algera Anne Geke
- Aliberti Anna
- Alkan Gulsum
- Alkhater Suzan
- Alkhater Suzan
- Allardet-Servent Jerome
- Allavena Clotilde
- Allende Luis
- Alonso-Arias Rebeca
- Alshahrani Mohammed
- Alsina Laia
- Alvarez Josep Trenado
- Alyanakian Marie-Alexandra
- Amador-Borrero Blanca
- Amat Karine
- Amoura Zahir
- Anaya Juan-Manuel
- Anderson Mark
- Anderson Mark
- Andreakos Evangelos
- Andreakos Evangelos
- Andrejak Claire
- Andrés Ana De
- Anglicheau Dany
- Angoulvant François
- Annereau Jean-Philippe
- AntolĂ Arnau
- Appelman Brent
- Arias Andrés
- Arias Andrés Augusto
- Arkin Lisa
- Arquero Miguel Fernandez
- Arranz MarĂa JesĂșs
- Arrestier Romain
- Arrestier Romain
- Asano Takaki
- Aschard Hugues
- Aubart MĂ©lodie
- Auguet Teresa
- Avramenko Iryna
- Aytekin Gökhan
- Aytekin Selma Erol
- Azot Axelle
- Azoulay Cecile
- Bachelet Delphine
- Bahram Seiamak
- Bajolle Fanny
- Baldanti Fausto
- Baldolli Aurélie
- Ballester Maite
- Baris-Feldman Hagit
- Barreiros Lucila
- Barrou Benoit
- Bartoli Marie
- Barzaghi Federica
- Basmaci Romain
- Basso Sabrina
- Bastard Paul
- Batten Isabella
- Bauters Fré
- Bax Diane
- Bayhan Gulsum Iclal
- Behillil Sylvie
- Behillill Sylvie
- Bellani Giacomo
- Belot Alexandre
- Belot Alexandre
- Belot Alexandre
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- Benkerrou Dehbia
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- Biggs Catherine
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- Brodin Petter
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- Christodoulou John
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- Sediva Anna
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- Sene Damien
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- SeppÀnen Mikko R.J.
- Shahrooei Mohammad
- Shahrooei Mohammed
- Sharif-Askari Fatemeh Saheb
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- Shcherbina Anna
- Shcherbina Anna
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- SĂĄnchez-RamĂłn Silvia
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- SĂžrensen Erik
- Taccone Fabio
- Talouarn Estelle
- Tanaka Junko
- Tancevski Ivan
- Tancevski Ivan
- Tandjaoui-Lambiotte Yacine
- Tandjaoui-Lambiotte Yacine
- Tangy Frédéric
- Tangye Stuart
- Tangye Stuart
- Tardivon Coralie
- Tardy Bernard
- Taupin Jean-Luc
- Tavernier Simon
- Tayoun Ahmad Abou
- Tellier Marie-Capucine
- Terrier Benjamin
- Terrier Olivier
- Teunissen Charlotte
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- Thibault Chloé
- Thiery Guillaume
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- Thorball Christian
- Thorn Karolina
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- Tiberghien Pierre
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- Tolstrup Martin
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- Trouillet-Assant Sophie
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- Troya JesĂșs
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- Tso Eugene
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- Tubiana Sarah
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- Turvey Stuart
- Tzourio Christophe
- Téoulé François
- Uddin K.
- Uddin Mohammed
- Ungeheuer Marie-Noëlle
- Ursini Matilde Valeria
- Utsumi Takanori
- Uzunhan Yurdagul
- Vabres Pierre
- Valencia-Ramos Juan
- Valsecchi Maria Grazia
- van Agtmael Michiel
- van Baarle Frank
- van Braeckel Eva
- van de Beek Diederik
- van de Beek Diederik
- van de Beek Diederik
- van den Rym Ana Maria
- van der Poll Tom
- van der Valk Marc
- van der Werf Sylvie
- van der Werf Sylvie
- van Mourik Niels
- van Praet Jens
- van Vugt MichĂšle
- Vanderlinden Dimitri
- Vandernoot Isabelle
- Vanel Noémie
- Vasse Marc
- Veelo Denise
- Veislinger Aurélie
- Velez-Santamaria Valentina
- Veliz Silvia Patricia Zuniga
- Venet Fabienne
- Vergara José Alejandro Daza
- Vidaur Loreto
- Vidaur Loreto
- Vidigal Mateus
- Vidigal Mateus
- Viel SĂ©bastien
- Vignali Valérie
- Vilaire-Meunier Marie
- Villain CĂ©dric
- Villar-GarcĂa Judit
- Vincent Audrey
- Vinh Donald
- Vinh Donald
- Visseaux Benoit
- Visseaux Benoit
- Vlaar Alexander
- Vogt Guillaume
- Voiriot Guillaume
- Volleman Carolien
- Volokha Alla
- von Bernuth Horst
- von Stemann Jakob Hjorth
- Vught Lonneke
- Vuotto Fanny
- VĂ©lez VerĂłnica Posada
- Waucquier Nawal
- Wauters Els
- Wauters Joost
- Wauters Joost
- Wauters Joost
- Wiedemann Aurélie
- Wiersinga W. Joost
- Wouters Dorien
- Wu Alan
- Wu Tak-Chiu
- YahĆi Aysun
- Yang Rui
- Yasar Kadriye Kart
- Yazdanpanah Yazdan
- Yazdanpanah Yazdan
- Yepes Jairo David Torres
- Yesilbas Osman
- Yildiz Mehmet
- Young Barnaby
- YĂŒkselmiĆ Ufuk
- Zatz Mayana
- Zatz Mayana
- Zatz Mayana
- Zawadzki Pawel
- Zhang Peng
- Zhang Qian
- Zhang Shen-Ying
- Zhang Yu
- Zimmer Christophe
- Zins Marie
- Zins Marie
- Zuccaro Valentina
- Zwinderman A.
- Ăñigo-Campos Antonio
- Ăz Ćadiye KĂŒbra TĂŒter
- Ăzkan Esra AkyĂŒz
- Ăzçelik Tayfun
- Publication venue
- 'Proceedings of the National Academy of Sciences'
- Publication date
- 24/05/2022
- Field of study
International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
- Author
- Abad Jorge
- Abel Laurent
- Abel Laurent
- Abel Laurent
- Abel Laurent
- Accordino Giulia
- Achille Cristian
- Acosta-Ampudia Yeny
- Agra Juan José Cåceres
- Aguilera-Albesa Sergio
- AguilĂł-Cucurull Aina
- Aiuti Alessandro
- Aiuti Alessandro
- Aiuti Alessandro
- Akcan Ăzge Metin
- Al-Muhsen Saleh
- Al-Mulla Fahd
- Alavoine Loubna
- Albert Matthew
- Albisures Jonathan Antonio Roblero
- Alcover Andres
- Aldave Juan
- Algera Anne Geke
- Aliberti Anna
- Alkan Gulsum
- Alkhater Suzan
- Alkhater Suzan
- Allardet-Servent Jerome
- Allavena Clotilde
- Allende Luis
- Alonso-Arias Rebeca
- Alshahrani Mohammed
- Alsina Laia
- Alvarez Josep Trenado
- Alyanakian Marie-Alexandra
- Amador-Borrero Blanca
- Amat Karine
- Amoura Zahir
- Anaya Juan-Manuel
- Anderson Mark
- Anderson Mark
- Andreakos Evangelos
- Andreakos Evangelos
- Andrejak Claire
- Andrés Ana De
- Anglicheau Dany
- Angoulvant François
- Annereau Jean-Philippe
- AntolĂ Arnau
- Appelman Brent
- Arias Andrés
- Arias Andrés Augusto
- Arkin Lisa
- Arquero Miguel Fernandez
- Arranz MarĂa JesĂșs
- Arrestier Romain
- Arrestier Romain
- Asano Takaki
- Aschard Hugues
- Aubart MĂ©lodie
- Auguet Teresa
- Avramenko Iryna
- Aytekin Gökhan
- Aytekin Selma Erol
- Azot Axelle
- Azoulay Cecile
- Bachelet Delphine
- Bahram Seiamak
- Bajolle Fanny
- Baldanti Fausto
- Baldolli Aurélie
- Ballester Maite
- Baris-Feldman Hagit
- Barreiros Lucila
- Barrou Benoit
- Bartoli Marie
- Barzaghi Federica
- Basmaci Romain
- Basso Sabrina
- Bastard Paul
- Batten Isabella
- Bauters Fré
- Bax Diane
- Bayhan Gulsum Iclal
- Behillil Sylvie
- Behillill Sylvie
- Bellani Giacomo
- Belot Alexandre
- Belot Alexandre
- Belot Alexandre
- Beluze Marine
- Benech Nicolas
- Benkerrou Dehbia
- Beretta Ilaria
- Bergin Colm
- Bertholon Frédérique
- Bettini Laura Rachele
- Beudel Martijn
- Bezrodnik Liliana
- Bhavsar Krishna
- Biggs Catherine
- Biggs Catherine
- Bilbao Agurtzane
- Bilguvar Kaya
- Biondi Andrea
- Bitker Laurent
- Bizien Lucy
- Blanchard-Rohner Geraldine
- Blanco Ignacio
- BlandiniĂšres Adeline
- Bleibtreu Alexandre
- Bloomfield Marketa
- BlĂĄzquez-Gamero Daniel
- Bogaard Harm Jan
- Bogunovic Dusan
- Boisson Bertrand
- Bolivar-Prados Mireia
- Bolze Alexandre
- Bomers Marije
- Bondarenko Anastasiia
- Bondarenko Anastasiia
- Bondarenko Anastasiia
- Bonfanti Paolo
- Bonneaudeau Brigitte
- Bonta Peter
- Borghesi Alessandro
- Borie Raphael
- Borrero Blanca Amador
- Bos Lieuwe
- Bosteels CĂ©dric
- Botdhlo-Nevers Elisabeth
- Botelho-Nevers Elisabeth
- Botta Michela
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- Bouadma Lila
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- Boudhabhay Idris
- Bouiller KĂ©vin
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- Bourgeon Marilou
- Bourke Nollaig
- Bourke Nollaig
- Bourke Nollaig
- Bouscambert-Duchamp Maude
- Bousfiha Ahmed
- Bousfiha Ahmed
- Bousfiha Ahmed
- Bousquet Aurore
- Bousso Philippe
- Boutolleau David
- Bouvattier Claire
- Boyarchuk Oksana
- Boyarchuk Oksana
- Bozdemir Ćefika Elmas
- Bravais Juliette
- Briones M. Luisa
- Briseño-Roa Luis
- Brodin Petter
- Brodin Petter
- Brouwer Matthijs
- Bruhns Pierre
- Bruneau LĂ©a
- Brunner Marie-Eve
- Bruno Raffaele
- Bryceson Yenan
- Bueno Maria Rita P.
- Bugiani Marianna
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- Burdet Charles
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- Chair Anissa
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- Chalumeau Martin
- Charbit Bruno
- Charpentier Charlotte
- Chauvineau-Grenier Angélique
- Chen Jie
- Cheng Matthew
- Chirouze Catherine
- Chirouze Catherine
- Chouchane Osoul
- Chrabieh Maya
- Christodoulou John
- Ciceri Fabio
- Citerio Giuseppe
- Clavé Pere
- Clercq Jozefien De
- Cloherty Alex
- Clotet Bonaventura
- Cobat Aurélie
- Codina Anna
- Coelho Alexandra
- Coeuret-Pellicer Mireille
- Cognasse Fabrice
- Cognasse Fabrice
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- Combes Alain
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- Condino-Neto Antonio
- Conlon Niall
- Connolly Emma
- Constantinescu Stefan
- Conti Francesca
- Contro Ernesto
- Cooper Megan
- Cordel Hugues
- Correales Luisa Paola Duarte
- Corsico Angelo
- Couffignal Camille
- Couffin-Cadiergues Sandrine
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- Cumano Ana
- Cvetkovski Aleksandar
- Cyrus Cyril
- Daganou Maria
- Dalgard Clifton
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- Dalmau David
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- Dauger Stéphane
- de Brabander Justin
- de Bree Godelieve
- de Bruin Sanne
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- Debette Stéphanie
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- Demirkol Yasemin Kendir
- Demoule Alexandre
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- Deplanque Dominique
- Deriano Ludovic
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- Desille-Dugast Mireille
- Desmarets Maxime
- Desvallée Mathilde
- Di Sabatino Antonio
- Di Santo James
- Diallo Alpha
- Diego Rebeca PĂ©rez De
- Diehl Jean-Luc
- Diehl Jean-Luc
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- Ding Li
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- Djossou FĂ©lix
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- Dongelmans Dave
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- Dunne Jean
- Dupont Annabelle
- Duval Xavier
- Duval Xavier
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- Dyer Adam
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- Ecobichon Jean-Luc
- Ekwall Olov
- El Baghdadi Jamila
- El Bakkouri Jalila
- Elbers Paul
- Elnagdy Marwa
- Eloy Philippine
- Emiroglu Melike
- Endo Akifumi
- Enninga Jost
- Enouf Vincent
- Enouf Vincent
- Epaulard Olivier
- Erdeniz Emine Hafize
- Erikstrup Christian
- Erikstrup Christian
- Esperou HĂ©lĂšne
- Espinosa-Padilla Sara
- Esposito-Farase Marina
- Espérou HélÚne
- Etienne Manuel
- Eto Shohei
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- Falck Antonin
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- Fartoukh Muriel
- Faure Morgane
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- Fellay Jacques
- Fellay Jacques
- Fellay Jacques
- Ferrer Ricard
- Ferreres Jose
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- Flaig Amandine
- Fleuren Lucas
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- Flores Carlos
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- Fouchard Julie
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- Franco José Luis
- Francois Bruno
- Frezouls Wahiba
- Froidure Antoine
- FumadĂł Victoria
- Fung Kitty
- Fusco Francesca
- Gagneux-Brunon Amandine
- Gagro Alenka
- Gallian Pierre
- Garcia-Prat Marina
- GarcĂa Paula Andrea Gaviria
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- Garçon Pierre
- Gatineau Audrey Giraud
- Gaudet Alexandre
- Gault Nathalie
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- Gaymard Alexandre
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- Geerlings Suzanne
- Geijtenbeek Theo
- Gentile Stéphanie
- Gervais Adrian
- Ghirardello Stefano
- Ghosn Jade
- Gigante Tristan
- Gil-Herrera Juana
- Gilardin Laurent
- Gilardin Laurent
- Gilg Morgane
- Girbes Armand
- Girona-AlarcĂłn MĂČnica
- Gissot Valérie
- GodĂnez Karen Alejandra Cifuentes
- Goehringer François
- Goffard Jean-Christophe
- Goldberg Marcel
- Gomperts-Boneca Ivo
- Gonzales Nacho
- Gonzalez-Granado Luis
- GonzĂĄlez-Montelongo Rafaela
- Goorhuis Bram
- Gorochov Guy
- Got Stéphane Le
- Gregersen Peter
- Gregersen Peter
- Gribouval Olivier
- Grimbacher Bodo
- Grobusch Martin
- Guaqueta Jeser Santiago Grass
- Guedj Jérémie
- Guerder Antoine
- Gumucio Victor Daniel
- Gunst Jan
- Gut Marta
- Gålvez-Romero José Luis
- GĂ©rardin Patrick
- GĂłmez Oscar
- GĂŒlhan Belgin
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- Haerynck Filomeen
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- Milner Joshua
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- Mironska Kristina
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- Mizoguchi Yoko
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- Morandeira Francisco
- Morandeira Francisco
- Morange Pierre-Emmanuel
- Mordacq Clémence
- Morel Pascal
- Morel Pascal
- Morelle Guillaume
- Morio Tomohiro
- Morio Tomohiro
- Mouly Stéphane
- Mouquet Hugo
- Mouquet Hugo
- Mullaert Jimmy
- Muñoz-Barrera Adriån
- MĂšge Jean-Louis
- MĂ©garbane Bruno
- Ménager Mickaël
- Nadif Rachel
- Nadji Seyed Alireza
- Naesens Leslie
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- Navarro Laura Mancera
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- Nellen Jeaninne
- Nemirowskaya Yelena
- Neven Bénédicte
- Neves JoĂŁo Farela
- Ng Lisa
- Ng Lisa
- Ng Yuk-Yung
- Nguyen Duc
- Nguyen Duc
- Ni Cheallaigh Cliona
- Nielly Hubert
- Noonan Claire
- Noret Marion
- Nossent Esther
- Notarangelo Luigi
- Notarangelo Luigi
- Nouroudine Mariama
- Novelli Antonio
- Novelli Giuseppe
- Nukui Yoko
- Nussenzweig Michel
- Ocejo-Vinyals J. Gonzalo
- Okada Satoshi
- Okada Satoshi
- Okamoto Keisuke
- Okamoto Keisuke
- Oriol Roger Colobran
- Ostrowski Sisse Rye
- Oualha Mehdi
- Ouedrani Amani
- Ozcelik Tayfun
- Ozcelik Tayfun
- Ozguler Anna
- Ozkaya-Parlakay Aslinur
- Oâfarrelly Cliona
- Oâfarrelly Cliona
- Oâfarrelly Cliona
- Pagani Michele
- Pan-Hammarström Qiang
- Pan-Hammarström Qiang
- Pan-Hammarström Qiang
- Papadaki Maria
- Papadopoulos Aurélie
- Pape Jean
- Paris Christophe
- Parizot Christophe
- Parola Philippe
- Parra-MartĂnez Alba
- Pascreau Tiffany
- Patin Etienne
- Paul Christelle
- Paul Stéphane
- Paul Stéphane
- Paulsen Isabella Worlewenut
- Paulus Frederique
- Payet Christine
- Paz Pauline Caraux
- Paz-Artal Estela
- Pedersen Ole Birger
- Pedraza-SĂĄnchez Sigifredo
- Peiffer-Smadja Nathan
- Peigne Vincent
- Pelet Anna
- Pelet Sophie
- Pellecer Nancy Carolina GonzĂĄlez
- Pellegrini Sandra
- Pellegrini Silvia
- Pereira Jesus Marquez
- Perez-Tur Jordi
- Perlin David
- Perreau Pauline
- Perroquin Magali
- Pesci Alberto
- Pesole Graziano
- Pession Andrea
- Peters Edgar
- Peterson PĂ€rt
- Petrov-Sanchez Ventzislava
- Peytavin Gilles
- Pham Huong
- Philippe Aurélien
- Philippot Quentin
- Philippot Quentin
- Picod Adrien
- Picone Olivier
- Piemonti Lorenzo
- Pina-Fuentes Dan
- Piquard Valentine
- Piquard Valentine
- Piralla Antonio
- Pistone Thierry
- Planas Anna
- Planas Anna
- Planas-Serra Laura
- Ploin Dominique
- Poissy Julien
- Poissy Julien
- Poissy Julien
- Poncelet GĂ©raldine
- Poulakou Garyphallia
- Pouletty Marie
- Pourshahnazari Persia
- Prado Maria Yolanda Ruiz Del
- Prando Carolina
- Prando Carolina
- Preckel Bennedikt
- Prins Jan
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- Pueyo David MartĂnez
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- Pujol Aurora
- Puéchal Oriane
- PĂ©rez Cristian Alejandro Ricaurte
- PĂ©rez-DĂaz Carlos
- Pérez-Fernåndez Xosé Luis
- Qiu-Chen Jia Li
- Quaresima Virginia
- Quentric Paul
- Quintana-Murci Lluis
- Quintana-Murci Lluis
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- Quintin Caroline
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- Raasveld Jorinde
- Ramaswamy Sathishkumar
- Rambaud Thomas
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- Ramos Miquel Alfonso
- Raoult Didier
- Raoult Didier
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- Reddy Conor
- Redin Claire
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- Richard Pascale
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- Stilma Willemke
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- Su Helen
- Su Helen
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- SĂĄnchez-MontalvĂĄ AdriĂĄn
- SĂĄnchez-RamĂłn Silvia
- SĂ€rekannu Karita
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- SĂžrensen Erik
- Taccone Fabio
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- Tanaka Junko
- Tancevski Ivan
- Tancevski Ivan
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- Tandjaoui-Lambiotte Yacine
- Tangy Frédéric
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- Tangye Stuart
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- Taupin Jean-Luc
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- Trouillet-Assant Sophie
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- Troya JesĂșs
- Tsang Owen
- Tserel Liina
- Tso Eugene
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- Tubiana Sarah
- Tubiana Sarah
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- Tuinman Pieter
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- Téoulé François
- Uddin K.
- Uddin Mohammed
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- Ursini Matilde Valeria
- Utsumi Takanori
- Uzunhan Yurdagul
- Vabres Pierre
- Valencia-Ramos Juan
- Valsecchi Maria Grazia
- van Agtmael Michiel
- van Baarle Frank
- van Braeckel Eva
- van de Beek Diederik
- van de Beek Diederik
- van de Beek Diederik
- van den Rym Ana Maria
- van der Poll Tom
- van der Valk Marc
- van der Werf Sylvie
- van der Werf Sylvie
- van Mourik Niels
- van Praet Jens
- van Vugt MichĂšle
- Vanderlinden Dimitri
- Vandernoot Isabelle
- Vanel Noémie
- Vasse Marc
- Veelo Denise
- Veislinger Aurélie
- Velez-Santamaria Valentina
- Veliz Silvia Patricia Zuniga
- Venet Fabienne
- Vergara José Alejandro Daza
- Vidaur Loreto
- Vidaur Loreto
- Vidigal Mateus
- Vidigal Mateus
- Viel SĂ©bastien
- Vignali Valérie
- Vilaire-Meunier Marie
- Villain CĂ©dric
- Villar-GarcĂa Judit
- Vincent Audrey
- Vinh Donald
- Vinh Donald
- Visseaux Benoit
- Visseaux Benoit
- Vlaar Alexander
- Vogt Guillaume
- Voiriot Guillaume
- Volleman Carolien
- Volokha Alla
- von Bernuth Horst
- von Stemann Jakob Hjorth
- Vught Lonneke
- Vuotto Fanny
- VĂ©lez VerĂłnica Posada
- Waucquier Nawal
- Wauters Els
- Wauters Joost
- Wauters Joost
- Wauters Joost
- Wiedemann Aurélie
- Wiersinga W. Joost
- Wouters Dorien
- Wu Alan
- Wu Tak-Chiu
- YahĆi Aysun
- Yang Rui
- Yasar Kadriye Kart
- Yazdanpanah Yazdan
- Yazdanpanah Yazdan
- Yepes Jairo David Torres
- Yesilbas Osman
- Yildiz Mehmet
- Young Barnaby
- YĂŒkselmiĆ Ufuk
- Zatz Mayana
- Zatz Mayana
- Zatz Mayana
- Zawadzki Pawel
- Zhang Peng
- Zhang Qian
- Zhang Shen-Ying
- Zhang Yu
- Zimmer Christophe
- Zins Marie
- Zins Marie
- Zuccaro Valentina
- Zwinderman A.
- Ăñigo-Campos Antonio
- Ăz Ćadiye KĂŒbra TĂŒter
- Ăzkan Esra AkyĂŒz
- Ăzçelik Tayfun
- Publication venue
- 'Proceedings of the National Academy of Sciences'
- Publication date
- 24/05/2022
- Field of study
International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population