383 research outputs found

    Quality of Cancer Registry Data

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    Cancer registry is a growing field and with data being collected year round the data needs to be of good quality standing. Quality of cancer care is measurable per standards when met within the time frame allotted per care regimen. Cancer programs are evaluating and implementing new process to make their data valid and complete through information technology and connection among hospital-based and community-based practices. The aim of this study is to review the available validity, barriers and utilization related to quality of cancer care data. The studies were consistent among each other in that a concurrent review of data, real-time collection, will be valid to the standards in cancer care. Rapid Quality Reporting System is still in its prime stage and the studies have concluded that using the reporting tool is best

    LA TÉCNICA DE INDAGACIÓN PARA MEJORAR LA ACTITUD CIENTÍFICA DE LOS ESTUDIANTES DE 3° GRADO DE EDUCACIÓN PRIMARIA DE LA INSTITUCIÓN EDUCATIVA PARROQUIAL PADRE ABAD, TINGO MARÍA 2018

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    La presente investigación tuvo la finalidad de demostrar la influencia de la técnica de Indagación en la actitud científica en el área de Ciencia y Tecnología en los estudiantes del 3° Grado de Educación Primaria La investigación es experimental con un diseño cuasi experimental con dos grupos. La población lo constituyeron 70 estudiantes del 3° Grado de Educación Primaria de la Institución Educativa Parroquial Padre Abad, Tingo María-2018 y la muestra constituida por la misma población, es decir se refiere a una muestra universal donde la Sección A1 fue el grupo experimental y la Sección A2, el grupo control. El instrumento de toma de datos fue la ficha de observación. Los resultados de la presente investigación indican que la aplicación de la técnica de Indagación mejora la actitud científica en el área de Ciencia y Tecnología de los estudiantes de 3º Grado de Educación Primaria de la Institución Educativa Parroquial Padre Abad, Tingo María-2018, puesto que en la prueba de hipótesis la t calculada es mayor que la t tabulada o crítica, así también el valor del nivel crítico es menor que el error estimado; del mismo modo al aplicar la técnica de indagación los estudiantes del grupo experimental mejoran sustancialmente la actitud científica y de sus dimensiones pasando de una valoración mediana a una valoración alta.Tesi

    El aprendizaje y sus condiciones: una relación singular en profesores universitarios

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    Those papers organized a fenomenous' element of the university professors' learning conceptions: the conditions as external variable that have influence on learning. It studies the features that those conditions assume on the teacher perspective and the teacher and the link that is built from there to around the knowledge to teach. It study institutional and organizational variable that surround the learning process and delimit those approach to the knowledge. It focuses on the analysis and interpretation of where is the main object take up on the discourse about learning.The disciplinary study object it is recognize as the learning condition more relevant and the distinctive features of the institutional organization it recognize as a frame of these learning’s. The learning times on the curricula performer working time with the knowledge that act out as learning mechanism from the professors conception.El presente trabajo sistematiza un elemento del fenómeno de las con­cepciones de aprendizaje en profesores universitarios: las condiciones en tanto variables externas que influyen en los aprendizajes. Se estudian las características que asumen dichas condiciones en la perspectiva de docentes universitarios y la trama que se construye a partir de allí en torno al conocimiento a enseñar. Dicho objeto de estudio es construido desde la perspectiva fenomenográfica. Puesto que interesa conocer el modo en que los docentes experimentan, explican y conceptualizan los aprendizajes. En tanto estrategia cualitativa habilita el abordaje situado de la problemática, nos acerca a las prácticas reales de enseñanza y los procesos de aprendizajes generados en la Universidad. Se abordan las variables institucionales y organizacionales que los contextualizan los procesos de aprendizaje y enmarcan esos acercamientos al conocimien­to. Se focaliza en el análisis e interpretación del lugar que ocupa el ob­jeto de estudio en el discurso respecto del aprendizaje. Así, el objeto de estudio disciplinar se reconoce como la condición de aprendizaje más relevante y las particularidades de la organización institucional se reco­nocen como marco de estos aprendizajes. Los tiempos académicos de cursada de las asignaturas generan espacios de trabajo con el conoci­miento que operan como dispositivo de aprendizaje desde la concepción de estos profesores

    Development of an ionic-liquid-based dispersive liquid–liquid microextraction method for the determination of antichagasic drugs in human breast milk. Optimization by central composite design

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    Chagas disease constitutes a major public health problem in Latin America. Human breast milk is a biological sample of great importance for the analysis of therapeutic drugs, as unwanted exposure through breast milk could result in pharmacological effects in the nursing infant. Thus, the goal of breast milk drug analysis is to inquire to which extent a neonate may be exposed to a drug during lactation. In this work, we developed an analytical technique to quantify benznidazole and nifurtimox (the two antichagasic drugs currently available for the medical treatment) in human breast milk, with a simple sample pre-treatment followed by an ionic-liquid-based dispersive liquid–liquid microextraction combined with high-performance liquid chromatography and UV detection. For this technique, the ionic liquid 1-octyl-3-methylimidazolium hexafluorophosphate has been used as the “extraction solvent”. A central composite design was used to find the optimum values for the significant variables affecting the extraction process: volume of ionic liquid, volume of dispersant solvent, ionic strength, and pH. At the optimum working conditions, the average recoveries were 77.5 and 89.7%, the limits of detection were 0.06 and 0.09 μg mL-1 and the inter-day reproducibilities were 6.25 and 5.77% for benznidazole and nifurtimox, respectively. The proposed methodology can be considered sensitive, simple, robust, accurate, and green.Universidad Nacional de La Plata (UNLP) - Facultad de Ciencias Exacta

    Weathering in the Forelands of Two Rapidly Retreating Alpine Glaciers of Volcanic Bedrock in the Three Sisters, Oregon, USA

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    The glaciers of the Three Sisters volcanoes in Cascadia have retreated dramatically over the past century. In order to understand ongoing chemical weathering and solute transport in the proglacial valleys, waters were sampled from glacier outwash streams, local snowmelt, and proglacial springs and lakes at Collier and Diller Glaciers. To understand weathering and transport processes in the proglacial plains, infrared orbital remote sensing data was used to map compositional variability and highlight weathering products, which were then ground-truthed with laboratory mineralogical and chemical analyses of sediments. The hydrochemistry is significantly affected by a sub- and proglacial mafic weathering system lacking carbonate minerals. Here we report major ion concentrations in meltwaters for the summer 2016 and 2017 melt seasons. Total cation concentrations range from 3 to 250 eq/l and dissolved bicarbonate concentrations range from 2 to 200 eq/l. Other dissolved anions are negligible compared to bicarbonate. Dissolved silica concentrations range from 2 to 260 mol/l, comparable to total dissolved cation concentrations. The highest cation and silica concentrations were measured in moraine-sourced springs. Compositional remote sensing analysis identified alteration zones in the proglacial plains at both Collier and Diller indicating potential hydrated silica. This analysis is consistent with laboratory analysis of sediment samples, which indicate the presence of poorly crystalline phases weathering products, including hydrated silica. Weathered materials are preferentially deposited on moraines due to aeolian and glacial transport, as well as intra-moraine alteration, and at abandoned stream terraces due to fluvial transport. Geochemical measurements indicate that the predominant form of chemical weathering in these periglacial mafic systems is the carbonation of feldspar as well as reactive volcanic glass. The presence of poorly crystalline silicates, as indicated by remote sensing datasets and laboratory analysis, is consistent with rapid weathering of feldspars and glass and formation of Fe-Al-Si-bearing mineraloids in these proglacial valleys. This weathering regime has wide-ranging implications for atmospheric CO2 drawdown due to cold-climate volcanic rock weathering

    Curso opcional: El proyecto de arquitectura con las energías

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    La figura del curso opcional en la enseñanza de grado de la Facultad de Arquitectura es reciente, por lo que el curso ‘El Proyecto con las Energías’ forma parte de las primeras experiencias en esta casa de estudio que tratan de aportar a un perfil determinado de profesional

    Informe anatomo-patológico de un tumor óseo de células gigantes en localización no habitual

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    The case of a male, aged 29, which showed destruction of the L5 vertebral body and was diagnosed with giant cell tumor of bone (osteoclastoma) is presented. Imaging studies and morphological elements of the tumor are shown. The unusual presentation in vertebra and the existence of other tumoral and tumor like lesions of bone which contained giant cells motivated us to review the literature to establish the pathological discussion with reference to histopathological criteria and other aspects that are necessary for the differential diagnosis.Se presenta un varón de 29 años de edad en el que se demostró la destrucción del cuerpo vertebral de L5 y se diagnosticó un tumor de células gigantes de hueso (osteoclastoma); se muestran estudios de imagen y elementos morfológicos del tumor. La presentación no habitual en vértebra y la existencia de otras lesiones pseudotumorales y tumorales de hueso que contienen células gigantes motivaron a revisar la literatura médica para establecer la discusión patológica y tomar como referencia criterios histopatológicos  y otros aspectos necesarios para el diagnóstico diferencial

    Comparison of SWAN and WISE Menopausal Status Classification Algorithms

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    Background: Classification of menopausal status is important for epidemiological and clinical studies as well as for clinicians treating midlife women. Most epidemiological studies, including the Study of Women's Health Across the Nation (SWAN), classify women based on self-reported bleeding history. Methods: The Women's Ischemia Syndrome Evaluation (WISE) study developed an algorithm using menstrual and reproductive history and serum hormone levels to reproduce the menopausal status classifications assigned by the WISE hormone committee. We applied that algorithm to women participating in SWAN and examined characteristics of women with concordant and discordant SWAN and WISE classifications. Results: Of the 3215 SWAN women with complete information at baseline (1995–1997), 2466 (76.7%) received concordant classifications (kappa = 0.52); at the fifth annual follow-up visit, of the 1623 women with complete information, 1154 (72.7%) received concordant classifications (kappa = 0.57). At each time point, we identified subgroups of women with discordant SWAN and WISE classifications. These subgroups, ordered by chronological age, showed increasing trends for menopausal symptoms and follicle-stimulating hormone (FSH) and a decreasing trend for estrogen (p < 0.001). Conclusions: The WISE algorithm is a useful tool for studies that have access to blood samples for hormone data unrelated to menstrual cycle phase, with or without an intact uterus, and no resources for adjudication. Future studies may want to combine aspects of the SWAN and WISE algorithms by adding hormonal measures to the series of bleeding questions in order to determine more precisely where women are in the perimenopausal continuum.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/63232/1/jwh.2006.15.1184.pd

    Development of an impedimetric immunosensor to determine microcystin-LR: New approaches in the use of the electrochemical impedance spectroscopy was used in determining to determine kinetic parameters of immunoreactions

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    The development of new electrochemical immunosensors for the detection of environmental contaminants is of great interest due to their simplicity, high sensitivity, and extended analytical range. Because of the antibody is immobilized on the electrode, it is important to determine its loss of reactivity after immobilization. In this work, two aspects were addressed. First, we developed a new methodology based on electrochemical impedance (EI) to determine the kinetic parameters associated with immunoreactions carried out on the electrode. Second, an electrochemical immunosensor based on electrochemical impedance spectroscopy (EIE) was developed to determine microcystin-LR in drinking water samples. Microcystin-LR determination was based on a label-free non-competitive immunoassay. The electrochemical immunosensor shows a limit of detection (LOD) of 33 pg mL−1 (3.32 × 10−11 mol L−1 or 0.033 μg L−1) which is well below the WHO guideline recommendation of 1 μg L−1 and 40 times better than the LOD obtained using the same antibody in an optimized conventional competitive ELISA assay. In addition, an acceptable accuracy, with recovery percentages close to 100% were found. The label-free immunosensor is a valuable tool to monitor microcystin-LR in drinking water samples and the environment.Fil: Boffadossi, Micaela. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaFil: Di Tocco, Aylen. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaFil: Lassabe, Gabriel. Universidad de la República; UruguayFil: Pirez Schirmer, Macarena. Universidad de la República; UruguayFil: Robledo, Sebastian Noel. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ingeniería. Departamento de Tecnología Química; ArgentinaFil: Fernandez, Hector. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaFil: Zon, María Alicia. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaFil: González Sapienza, Gualberto. Universidad de la República; UruguayFil: Arevalo, Fernando Javier. Universidad Nacional de Río Cuarto. Instituto para el Desarrollo Agroindustrial y de la Salud. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto para el Desarrollo Agroindustrial y de la Salud; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentin
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