Low Handgrip Strength Levels in Non-Athlete Adolescents Compared to Adolescent Athletes

Handgrip strength is an important determinant of general health. The primary purpose of this study is to examine the handgrip strength levels in adolescents in terms of sports participation. The second purpose is to determine the association between handgrip strength and other strength parameters. Physically active adolescent athletes (n = 31, 14.26 ± 0.68 years), and the age, pubertal stage and gender-matched non-athlete adolescents (n = 31, 14.21 ± 0.66 years) at the age of 13 to 15 participated in the study. Maximum isometric muscle strength for hand, leg, and back were measured with a handheld dynamometer. Handgrip strength was correlated with leg strength and back strength (r=0.675; r=0.698, respectively). Non-athletes had lower strength values compared to the athletes (98.48 ± 38.25 kg vs 82.94 ± 33.70 kg; 91.48 ± 35.23 kg vs 70.35 ± 25.81 kg; 30.53 ± 7.05 kg; 25.97 ± 5.98 kg for leg, back and handgrip strength, respectively). There was a positive correlation between handgrip strength and other strength parameters in adolescents. Therefore, handgrip strength can be used as a general strength indicator in adolescents. Sports participation in adolescents seems to increase strength parameters notably and may affect health correlatively

Conservation and evaluation of historical and monumental educational structures case study Antalya High School

Since the period that they started to emerge, cities are formed by the history that the civilizations take from the past, with the cultural values and the geography that they are in. The cities, which exist within this development process throughout civilizations, brought along the structures that are considered to be urban heritage and are occurred within the economic, social, societal and spatial feature and necessity. This process continues its existence with a lot of examples throughout the civilization history both in the world and in our country. There is an important variety between the historical structures that occur in our cities. Cities with the civil architecture examples and public buildings have a wide range of features that give them their identity constructions. One of the important structures that occur within this wide range is the training facilities, which started from the Ottoman Period and continued until the Republican Period and showed an increase. The education system, which started as madrassas and mosques in the Ottoman Period and later on turned into high schools and schools, and its structure are the important urban symbols in our cities. In this study, the protection and survival of the training facilities, which are historical and cultural inventories and reflect their periodical features and city identity, will be discussed. Within this scope, Antalya High School, which is one of the historical training facilities in Antalya, is taken as a sample. Antalya High School, concerning its history and statue, is city’s one of the important historical and social symbols. It is an important heritage that must be protected and maintained, since it reflects the cultural, social and architectural features of its history. Within the scope of the study, some examples of the historical training facilities, which have the similar statue in our country, are investigated to reach a general evaluation and within the sample area the study is detailed. The historical development of the investigated structure and its today’s position are investigated with environmental structures, and suggestions are made for protection – use – assessment. Analysis of the current situation is reinforced with the pedestrian counts and observational rapid assessment methods applied to structures and both quantitative and qualitative data could be reached for the study base. An evaluation was made for probable actions that aim the protection and survival of the urban and structural development within the historical process. When a further step is to be thought of this study, which is made with parcel scale, it should not be forgotten that this study will serve as an intermediate product for future evaluation and conversion studies on urban scale with the context of Urban Planning

THE EFFECT OF COMMUNICATION SKILLS OF FOOTBALL COACHES ON THE FOOTBALLERS' MOTIVATION FOR SUCCESS

The main purpose of our study is to determine the relationship between the level of communication between amateur football players and their coaches and their motivation for success, also to reveal whether variables such as education status, the time of working with the trainers and the time to exercise have an effect on their communication levels and motivation for success. In the scope of the research, 65 amateur football players selected among 10 amateur football clubs in the district of Esenyurt, Istanbul has been examined. As data collection tools in our study, Sports-Specific Achievement Motivation Scale (SSAMS) and Coach Communication Scale in Football (CCSF) were used. Also, Mann-Whitney U test was used to compare variables while Pearson's correlation test was utilized to examine the relationship between variables. As a result of the examination, when the communication skills of the participants were evaluated according to age, a significant difference was found in the 14-16 age groups. Also, when the communication skills of the participants were evaluated according to their educational status, a significant difference was found at the high school level. In addition, when the success motivation sub-dimensions of football players are evaluated, a significant difference is observed in the 14-16 age groups in their motivation to show power and achieve success. When the participants' motivation to show power was evaluated according to their amount of time of spent on sports, it was found that there was a significant difference between 6-10 years, and when the motivation to achieve success was evaluated according to the duration of working with the same trainer, a significant difference was found in those who exercised for 3-5 years. While a weak positive correlation was found between the motivation to show power and the motivation to succeed (

Possible role of GADD45γ methylation in diffuse large B-cell Lymphoma: Does it affect the progression and tissue involvement?

Objective: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma among adults and is characterized by heterogeneous clinical, immunophenotypic, and genetic features. Different mechanisms deregulating cell cycle and apoptosis play a role in the pathogenesis of DLBCL. Growth arrest DNA damage-inducible 45 (GADD45γ) is an important gene family involved in these mechanisms. The aims of this study are to determine the frequency of GADD45γ methylation, to evaluate the correlation between GADD45γ methylation and protein expression, and to investigate the relation between methylation status and clinicopathologic parameters in DLBCL tissues and reactive lymphoid node tissues from patients with reactive lymphoid hyperplasia. Materials and Methods: Thirty-six tissue samples of DLBCL and 40 nonmalignant reactive lymphoid node tissues were analyzed in this study. Methylation-sensitive high-resolution melting analysis was used for the determination of GADD45γ methylation status. The GADD45γ protein expression was determined by immunohistochemistry. Results: GADD45γ methylation was frequent (50.0%) in DLBCL. It was also significantly higher in advanced-stage tumors compared with early-stage (p=0.041). In contrast, unmethylated GADD45γ was associated with nodal involvement as the primary anatomical site (p=0.040). Conclusion: The results of this study show that, in contrast to solid tumors, the frequency of GADD45γ methylation is higher and this epigenetic alteration of GADD45γ may be associated with progression in DLBCL. In addition, nodal involvement is more likely to be present in patients with unmethylated GADD45γ. © 2015 Turkish Society of Hematology. All rights reserved

Evaluation of the Effects of Varicoceles and Fertility Status on Volumetry and Shear-wave Elastography

Aim: This study aims to compare the volumetry and shear-wave elastography findings in infertile and fertile patients and evaluate the effect of presence of varicoceles on the parameters. Materials-Methods: 40 infertile and 20 fertile patients (120 testes) (mean age 29,3±6,7) between January 2018-November 2018 were included in this prospective study. All patients underwent testicular B-mode and doppler ultrasonography (US) and shear-wave elastography (SWE). Patients were sub-grouped according to fertility status and presence or absence of varicoceles. Results: Testis stiffness was significantly higher in testes without varicoceles than those with varicoceles (p=0.021). It was also higher in fertile patients than infertile patients (p=0.015). Testes volumes were higher in fertile patients and patients with varicoceles (p=0.011 and p=0.028, respectively). Conclusion: SWE is a non-invasive, cheap and reproducible technique with promising results for diagnosis and follow-up in the evaluation of infertility

Is biopsy necessary? Role of DCE-MRI in BIRADS-3 lesions

PURPOSEWe aimed to evaluate BIRADS-3 breast lesions with dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and compare with histopathology, and to investigate the effectiveness of breast MRI for follow-up and management.METHODSA total of 84 BIRADS-3 lesions reported by US or mammography and evaluated by DCE-MRI between September 2014 and October 2015 were included in this study. All patients underwent percutaneous or surgical biopsy for histopathologic diagnosis. Morphologic and kinematic features on MRI were compared with histopathologic results.RESULTSOf the 84 BIRADS-3 breast lesions, 9 (10.7%) had malignant features on DCE-MRI and all were verified with histopathologic results. DCE-MRI had 96.7% sensitivity, 72% specificity, 92% positive predictive value, and 82.5% negative predictive value. MRI and histopathology results were correlated for the diagnosis of malignant lesions. The sensitivity and negative predictive value of MRI for diagnosis of malignant lesions were both 100%.CONCLUSIONDifferentiation of benign versus malignant lesions was accomplished with 100% accuracy with DCE-MRI. We suggest that DCE-MRI should be an additional diagnostic tool and problem-solving modality for BIRADS-3 lesions, particularly in patients with relative risk factors

Mezenterik Kistik Lenfanjiom: BT Bulguları

Abdominal lenfanjiomlar oldukça seyrek görülen kistik lezyonlar olup en sık ince barsak mezenterinde yerleşim gösterir. Asemptomatik olabileceği gibi akut ya da kronik karın ağrısı ve distansiyon gibi nonspesifik semptomlar görülebilir. Ultrasonografi ile lezyonun kistik karakteri belirlenebilmekle beraber kompleks anatomik ilişkilerinin saptanabilmesi için BT ve MRG gereklidir. Çalışmamızda çok kesitli BT incelemesinde insidental olarak saptanan, ince barsak mezenterinde lokalize kistik lenfanjiom olgusunun bulguları sunulmuştur

The renoprotective effects of mannitol and udenafil in renal ischemia-reperfusion injury model

Purpose: The aim of this study was to investigate and compare the effects of udenafil and mannitol in an experimental renal ischemia-reperfusion (I/R) injury model.Materials and Methods: A total of 64 female Wister Albino rats were used. Right nephrectomy was performed in all groups. In the control group; I/R injury was not performed. In the I/R group; left renal pedicle was clamped for 45 minutes and then underwent 60 minutes and 24 hours of reperfusion. In the mannitol group; 1 mL 20% mannitol was given intravenously 15 minutes before clamping. In the udenafil group; 10-mg/kg udenafil was given orally 1 hour before clamping. Creatinine (Cr), blood urea nitrogen (BUN), Cr clearance, malondialdehyde, neutrophil gelatinase associated lipocalin (NGAL), histological examination and DNA damage (Comet Assay method) levels were compared in tissue, serum and urine samples.Results: Udenafil had a better protective effect than mannitol according to biochemical parameters (Cr, BUN, Cr clearance, and NGAL levels) and histopathological findings when compared with the I/R group. In the Comet sampling analysis no significant difference was detected.Conclusions: Udenafil has a better renoprotective effect than mannitol against I/R injury and this effect supports more functional improvements. Further clinical trials are needed to demonstrate those effects and clinical utility of udenafil for that purpose in humans

Dobrava Hantavirus Infection Complicated by Panhypopituitarism, Istanbul, Turkey, 2010

We identified Dobrava-Belgrade virus infection in Turkey (from a strain related to hantavirus strains from nearby countries) in a patient who had severe symptoms leading to panhypopituitarism, but no known risk for hantavirus. Our findings emphasize the need for increased awareness of hantaviruses in the region and assessment of symptomatic persons without known risk factors for infection