Effect of Annual Precipitation and Temperature on the Performance of Wheat Varieties

Field Crop

Significance of physicochemical factors in the transmission of Escherichia coli and chloride

Background: Organic manures are the source of many pathogenic bacteria which could be dangerous for human health. Bacterial transmission and retention in soil is important for processes ranging from contaminant degradation during in situ bioremediation to transport of pathogenic bacteria into groundwater. Methods: The aim of this study was to evaluate the transport of Escherichia coli and chloride (Cl) in the soil saturation conditions, considering the importance of preferential flow using synthetic macrospores (different diameters of macrospores including 0, 1 and 2 cm) and HYDRUS-2D model. Also, the effect of different salinity levels of water (including electrical conductivity of 1, 2 and 4 dSm-1) on the transmission of E. coli was investigated. The preferential flow system was prepared and designed using two sand sizes including fine sand and coarse sands in the columns. Results: The results showed that the retention of E. coli increased with the ionic strength of the solution, while the effect of E. coli in the fine sand was greater than that of the coarse sand. This bacterial transfer behavior was well described by numerical simulations. The importance of preferential flow in bacterial transfer showed that it increases at higher ionic strength, even if overall transmission is reduced. Although the bacterial transmission is facilitated in salinity, the results of this study showed that with increase of ionic strength of the soil solution, the amount of bacterial purification was increased that could be effective in controlling groundwater contamination with saline water management. Conclusion: According to the results, with increase of ionic strength of the soil solution, the amount of bacterial purification was increased that could be effective in controlling groundwater contamination with saline water management, so that the least transition has taken place and the conditions for the use of unconventional water sources were also created, without the environmental problem of the risk of groundwater pollution. Keywords: Escherichia coli, Soil, Water pollutio

Globalization and Middle East: A glance to the globalization process

Globalization is compressing the world and increasing this knowledge that the world is a whole. This process challenges the government to the different and modern ways especially the governments facing many problems with the population. Globalization increases the national, tribalism and citizenship awareness so people dispute with the government to attend their rights. This action especially in the Middle East where many of the government still are trying to keep country-government model is seen. This article studies the globalization process and the problems of the Middle East

Functional and Structural Characterization of SARS-Cov-2 Spike Protein: An In Silico Study

BACKGROUND፡ Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the global outbreak of coronavirus disease 2019 (Covid-19), which has been considered as a pandemic by WHO. SARS-CoV-2 encodes four major structural proteins, among which spike protein has always been a main target for new vaccine studies. This in silico study aimed to investigate some physicochemical, functional, immunological, and structural features of spike protein using several bioinformatics tools.METHOD: We retrieved all SARS-CoV-2 spike protein sequences from different countries registered in NCBI GenBank. CLC Sequence Viewer was employed to translate and align the sequences, and several programs were utilized to predict B-cell epitopes. Modification sites such as phosphorylation, glycosylation, and disulfide bonds were defined. Secondary and tertiary structures of all sequences were further computed.RESULTS: Some mutations were determined, where only one (D614G) had a high prevalence. The mutations did not impact the B-cell and physicochemical properties of the spike protein. Seven disulfide bonds were specified and also predicted in several N-link glycosylation and phosphorylation sites. The results also indicated that spike protein is a non-allergen.CONCLUSION: In summary, our findings provided a deep understanding of spike protein, which can be valuable for future studies on SARS CoV-2 infections and design of new vaccines

Evaluation of Knowledge, Attitude, and Practice of Mothers Presenting to Pediatric Clinic Regarding Urinary Tract Infection Prevention in Children

Introduction: Urinary tract infection is one of the most common bacterial infections in children. It is preventable in many cases and appropriate health behaviors can protect a child from the disease or minimize its risk. Considering the relatively high prevalence of urinary tract infections in children and with regard to the important role of healthy behaviors in preventing this infection, we decided to evaluate the knowledge, attitude and practice of mothers regarding the prevention of urinary tract infections.Materials and Methods: This cross-sectional descriptive-analytic study was performed in the Pediatric Clinic of Imam Khomeini Hospital to determine the knowledge, attitude, and practice of mothers about UTI in children and to evaluate its relationships with some demographic features. The data collection tool was a researcher-made questionnaire based on the literature review. The collected data were analyzed using SPSS 22 software and P-values less than 5% were considered significant.Results: One hundred and fifteen mothers who presented to the Pediatric Clinic of Imam Khomeini Hospital participated in this study. The average knowledge, attitude, and practice score in the first part and the practice score in the second part was 6.21, 47.85, 13.86, and 10.66, respectively.A statistically significant relationship was found between the score of knowledge and attitude. The knowledge score had a significant relationship between maternal employment status, household income, and household location. There was also a significant relationship between access to information and both the knowledge and attitude scores.Conclusions: The significant relationship between access to information resources and the maternal knowledge and attitude scores confirms the importance of awareness in improving the knowledge of mothers in preventing urinary tract infection.Keywords: Knowledge; Attitudes; Practice; Urinary Tract Infections; Pediatrics

Developing an efficient deep neural network for automatic detection of COVID-19 using chest X-ray images

The novel coronavirus (COVID-19) could be described as the greatest human challenge of the 21st century. The development and transmission of the disease have increased mortality in all countries. Therefore, a rapid diagnosis of COVID-19 is necessary to treat and control the disease. In this paper, a new method for the automatic identification of pneumonia (including COVID-19) is presented using a proposed deep neural network. In the proposed method, the chest X-ray images are used to separate 2–4 classes in 7 different and functional scenarios according to healthy, viral, bacterial, and COVID-19 classes. In the proposed architecture, Generative Adversarial Networks (GANs) are used together with a fusion of the deep transfer learning and LSTM networks, without involving feature extraction/selection for classification of pneumonia. We have achieved more than 90% accuracy for all scenarios except one and also achieved 99% accuracy for separating COVID 19 from healthy group. We also compared our deep proposed network with other deep transfer learning networks (including Inception-ResNet V2, Inception V4, VGG16 and MobileNet) that have been recently widely used in pneumonia detection studies. The results based on the proposed network were very promising in terms of accuracy, precision, sensitivity, and specificity compared to the other deep transfer learning approaches. Depending on the high performance of the proposed method, it can be used during the treatment of patients

Effects of NDRG2 Overexpression on Metastatic Behaviors of HCT116 Colorectal Cancer Cell Line

Purpose: N-myc downstream-regulated gene 2 (NDRG2) is frequently down-regulated in cancer, and plays an important role in the control of tumor growth and metastasis. Its manipulation has been suggested as a therapy in cancer. Here, we examined the outcome of NDRG2 overexpression on proliferation, invasion, migration and MMP activity of HCT116 colorectal cancer cell line. Methods: The HCT116 cell line (human colorectal cancer) was transfected with pCMV6-AC-GFP-NDRG2. 2,5diphenyltetrazolium bromide (MTT) assay was used to detect cell proliferation. The invasion and migration of the transfected cells were examined through transwell chambers while the MMP-9 activity was detected by the ability of the cells to digest gelatin. Results: Overexpression of NDRG2 by stable NDRG2 transfection decreased cell proliferation, migration and invasion ability, along with decreasing MMP-9 activity. Conclusion: Our data indicate that NDRG2 overexpression can suppress several aspect of tumorigenesis. Further investigations are necessitated to verify if NDRG2 molecule can be a therapeutic target in colorectal cancer

Factorial Mixture Design for Properties Optimization and Modeling of Concrete Composites Incorporated with Acetates as Admixtures

Nowadays, admixtures are used with the aim to provide strength and durability to concrete with less water use. New and low-cost admixtures gained a large amount of consideration to mitigate the problems associated with concrete’s durability and service life without upsetting its strength properties. The current work investigates the effect of three types of acetates on the workability, density, and compressive strength of concrete, which is used in structures of the Iraqi ports that suffer from corrosion damages and deterioration owing to the aggressive marine environments. Potassium acetate (KA), calcium acetate (CaA), and ethyl acetate (EA) are incorporated with different doses (1.38–5.6 wt.% of cement) in concrete mixtures using different water/cement ratios (0.48–0.54) based on an espoused central composite experimental design. The experimental results confirmed that the average workability increased with increasing the acetate dose, particularly with CaA. The density and compressive strength of 28 days of water-cured mixtures increased with increasing acetate dose following the order: Ca > K > Ethyl acetate and decreased with increasing w/c ratio. The high rise in compressive strength and workability linked to control mixtures was 30.8% and 77.3% as well as 15.7% and 64.3% for the mixtures incorporated with 5.6 wt.% CaA and KA, respectively. While it was 14.2% and 58.3% for the mixtures incorporated with 3.5 wt.% EA. RSM was employed to optimize and model the design and hardened properties of concrete mixtures. ANOVA results predicted the same trend, which was obtained from the experimental results. The mathematical models were valued with high-regression coefficients. The highest compressive strength of 42.68 MPa has been achieved for a concrete mixture of 0.48 w/c ratio by the incorporation of 5.1 wt.% CaA through a model with R2 96.97%. The relatively low-cost acetate admixtures, particularly CaA, seemed promising for the fabrication of concrete with outstanding properties

New concrete composites incorporated with calcium acetate as admixture: The Impact of Curing Age on Strength and the Effect of Temperature on Water Absorption

In previous work, concrete mixes incorporated with different types of acetates (inorganic and organic) were formulated, cured for 28 days in water, and then tested for compressive strength. The effect of the water-to-cement ratio and the acetate content was optimized using a central composited design based on the response surface methodology approach. The results confirmed that the optimum compressive strength was achieved for the mixes incorporated with calcium acetate (CaA) using of 0.48 water-to-cement ratio. In the current work, the effect of curing age on compressive strength and density was studied for the optimum mixes. Also, the water absorption of the mixes carried out by immersion test was assessed at different temperatures (25-55 °C). Microscopic observations were also noted. The results obtained confirmed that the compressive strength and density of the CaA-concrete mix increase with increasing the curing age. The thermodynamic study of water absorption assured the dependence of water absorption on temperature. The activation energies depicted from the Arrhenius relation and the decrease in the water absorption rate for the concrete incorporated with CaA are considered as an indicator of decreasing the porosity of the concrete mixes compared to the control mixes without CaA. The findings assured that the modified mixes with CaA are promising construction materials owing to their outstanding strength and lower water absorption rates compared to conventional concrete

Enhancing Concrete Properties Using Silica Fume: Optimized Mix Design

In the current work, concrete mixes containing (7.0-33.11) weight % silica fume as a partial replacement of cement with a water /cement ratio (0.42-0.48) were prepared according to an adopted two factorial central composite design. The samples were tested, optimized, and modeled for compressive strength and density.  The estimated results confirmed that compressive strength and density increase with increasing silica fume content up to 11.9 wt.%. Response surface analysis results confirmed that silica fume concrete with developed compressive strength (53.42 MPa) could be prepared by incorporation of 11.9 wt. % silica fume as partial replacement of cement using 0.42 water/cement ratio. An increase in compressive strength and density (up to  39.3% and  2.6% ) respectively was recorded for silica fume concrete mixes compared to Portland cement concrete. Overall, the research findings revealed that silica fume concretes prepared with appropriate silica fume content and water/cement ratio exhibited superior strength and density characteristics candidate them to be used effectively in civil engineering applications