417 research outputs found
The Role of Information Systems Strategy in Driving Successful Digitalization: an IoT perspective
The Internet of things (IoT) has become one of the most significant topics in information systems (IS) industry yet; it still faces certain complications in its implementation process. The estimation of unsuccessful implementations are up to 60% Cisco (2017). Unsuccessful implementation could be due to many issues such as human resources, collaboration between information technology function (IT) and other business functions, cultural issues within organizations, etc... However, these issues are overcome with an appropriate IS strategy Arora et al. (2017). Although efforts were exerted to understand the factors of successful adoption of IoT, less efforts have been directed towards understanding these factors from an information systems strategy point of view. This study aims to identify the most important driving factors in an information systems strategy leading to successful implementation of IoT. A preliminary framework presenting the 10 IS driving factors leading to successful implementation of IoT is deduced from the literature. The developed framework is tested in two case studies within leading real estate developers who have successfully implemented IoT in various functions. Face to face semi structured interviews were administered and the results revealed that six main factors and nine sub factors were required to guide the IS strategy to successful adoption of IoT projects within an organizational context
Knowledge and Attitude of Medical Students of Cairo University, Cairo, Egypt About National DNA Database
Background: DNA database is used to identify individuals based on their specific DNA profiles. In Egypt, a definitive law describing and legalizing DNA related issues is absent; however, the Egyptian courts frequently deal with these issues. The legal authorities strongly suggest the impending need for detailed decrees in this regard that guard the safety of the whole Egyptian community. This paper aimed to assess the knowledge and attitude of Medical students about Egyptian National DNA Database (END). Methods: Data of this study were collected from 272 participants in the Faculty of Medicine, Cairo University using interviewer administered questionnaire. Results: The participants were 136 males and 136 females with mean (SD) age of 27(9) years. Majority of the participants (89.7%) were aware about national database out of their medical textbooks. Personal identification was the most chosen END benefit and database usefulness was the main motivation for them. About 29% suggested to start END with the detected crime scene stains and forensic doctors should freely access END. Conclusion: These collective points of views might be useful in preparing some international and common ethical standards for the development of DNA databases framework
Thermoanalytical Investigation of Terazosin Hydrochloride
Purpose: Thermal analysis (TGA, DTG and DTA) and differential scanning calorimetry (DSC) have been used to study the thermal behavior of terazosin hydrochloride (TER). Methods: Thermogravimetric analysis (TGA/DTG), differential thermal analysis (DTA) and differential scanning calorimetry (DSC) were used to determine the thermal behavior and purity of the used drug. Thermodynamic parameters such as activation energy (E*), enthalpy (H*), entropy (S*) and Gibbs free energy change of the decomposition (G*) were calculated using different kinetic models. Results: The purity of the used drug was determined by differential scanning calorimetry (99.97%) and specialized official method (99.85%) indicating to satisfactory values of the degree of purity. Thermal analysis technique gave satisfactory results to obtain quality control parameters such as melting point (273 ºC), water content (7.49%) and ash content (zero) in comparison to what were obtained using official method: (272 ºC), (8.0%) and (0.02%) for melting point, water content and ash content, respectively. Conclusion: Thermal analysis justifies its application in quality control of pharmaceutical compounds due to its simplicity, sensitivity and low operational costs. DSC data indicated that the degree of purity of terazosin hydrochloride is similar to that found by official method
Efeitos terapêuticos do Allium sativum e Allium cepa na infecção experimental pelo Schistosoma mansoni
The effects of both garlic (Allium sativum) and onion (Allium cepa) on some biochemical parameters in Schistosoma mansoni infected mice individually and mixed either with or without the currently used drug, praziquantel (PZQ) were investigated. These involved some immunological parameters, namely IgM, IgG, interleukins 2 and 6 (IL-2 and 6) and tumor necrosis factor (TNF-α), some antioxidant enzymes [catalase, superoxide dismutase (SOD) and glutathione peroxidase (GPX)]. In addition, parasitological and histopathological investigations were performed. No changes were observed in the normal control mice treated with dry extract of onion or garlic, individually or mixed, with or without PZQ, compared to the normal healthy control group. Infection with S. mansoni showed an increase in IgG, IgM, IL-2, IL-6, TNF-α and catalase enzyme, accompanied with a decrease in GPX and SOD antioxidant enzyme activities. Remarkable amelioration was noticed in the levels of all the measured parameters in S. mansoni infected mice after administration of the studied extracts. Moreover a significant reduction in worm burden, hepatic and intestinal eggs and oogram count was noticed which was reflected in normalization of liver architecture.Os efeitos do alho (Allium sativum) e cebola (Allium cepa) em parâmetros bioquímicos de camundongos infectados pelo Schistosoma mansoni individualmente e misturados seja com ou sem as drogas correntemente usadas como o Praziquantel (PZQ), foram investigados. Isto envolveu parâmetros imunológicos tais como IgM, IgG, Interleucina 2 e 6 (IL-2 e 6), fator de necrose tumoral (TNF-α) e algumas enzimas anti-oxidantes [catalase, super-óxido dismutase (SOD) e glutationa peroxidase (GPX)]. Em adição foram realizadas investigações parasitológicas e histopatológicas. Nenhuma alteração foi observada nos camundongos controles normais tratados com extrato seco de cebola ou alho, individualmente ou misturado, com ou sem PZQ, comparados com os controles normais sadios. Infecção com o Schistosoma mansoni revelou um aumento em IgG, IgM, IL-2, IL-6, TNF-α e catalase, acompanhados de diminuição do GPX e atividade enzimática do anti-oxidante SOD. Melhora acentuada foi notada nos níveis de todos os parâmetros medidos em camundongos infectados com Schistosoma mansoni após administração dos extratos estudados. Mais ainda, significante redução na quantidade de vermes, e ovos no fígado e intestino e na contagem do oograma foi notada refletindo a normalização da arquitetura do fígado
Specialized Publishing in Public Relations and the Challenges of Digitization from the Point of View of Professors
This study aims to identify the requirements of specialized publishing in public relations and the most important challenges it faces in the context of the digital environment that requires the transformation of scientific information and the methodology of writing it into electronic archive, which is mainly based on digital image and specialized design with the integration of technologies and multimedia. This transformation that has brought about fundamental changes In the process of publishing and distribution, which constitutes one of the basics of the knowledge society
A Primary Testicular Diffuse Large B-cell Lymphoma Belonging to the Germinal Center B-cell-like Group
Testicular lymphoma was first reported by Malassez and Curling in 1866. Primary testicular lymphoma constitutes only 1 - 7% of all testicular neoplasms and less than 1% of all non Hodgkin lymphoma. The authors report a new case of primary testicular lymphoma and highlight its diagnostic and therapeutic challenge. We report the case of a 26-year old man without a particular past medical history, who presented with a painful right testicular swelling that he has noticed for several weeks. Radiological findings consisted in multiple hypoechoic masses that corresponded in histological examination to a diffuse intratubular lymphomatous infiltration situated away from the spermatic cord, the epididymis, ductuli efferentes and rete testis. Immunohistochemical study showed positivity for leukocytic common antigen (CD45), B-cell marker (CD20) and bcl 6. The patient underwent full staging for lymphoma showing no evidence of extra-testicular involvement by lymphoma and no lymph nodes. The diagnosis of stage I primary testicular large B-cell lymphoma of germinal center B-cell-like group was made. The patient is now treated by chemotherapy. Primary testicular lymphoma is a rare tumour whose diagnosis is based on histological findings. There are non consensual etiological or predisposing factors. Treatment modalities consist in surgical excision, chemotherapy and radiation therapy but the accurate procedures are not standardized. Factors that have been linked to more favorable outcomes include younger patient age, localized disease, presence of sclerosis at pathologic analysis, smaller tumour size, lower histological tumor grade and lack of epididymal or spermatic cord involvement
Environmental efficiency of Saccharomyces cerevisiae on methane production in dairy and beef cattle via a meta-analysis
The objective of the present study is to examine the effect of yeast (Saccharomyces cerevisiae) on reduction of methane (CH4) production in dairy and beef cattle using meta-analytic methods. After compilation of relevant scientific publications available from the literature between 1990 and 2016, and applying exclusion and inclusion criteria, meta-analyses of data from dairy and beef cattle were applied for the pooled dataset or for each animal category (dairy or beef). The results of meta-analysis of all three datasets (all cattle, dairy cattle, or beef cattle) suggested that effect size of yeast either on daily CH4 production or on CH4 production per dry matter intake (CH4/DMI) was not significant. The results of Q test and I2 statistic suggest that there is no heterogeneity between different studies on CH4 production and CH4/DMI. The results of meta-analysis suggest that use of yeast (Saccharomyces cerevisiae) as feed additive does not offer significant results in terms of reduction of CH4 production in dairy and beef cattle. Further research on the effects of different doses of yeast, use of yeast products, different strains, and experimental designs is warranted to elucidate the effects of yeasts on methane production in the rumen
Plastic use for food and drinks and related knowledge, attitudes, and practices among a sample of Egyptians
IntroductionPlastic is extensively used in everyday life, particularly for food and beverage containers. The inappropriate use of these containers may lead to the leaching of various chemicals from plastic, such as bisphenol A, phthalate, and styrene, which cause numerous adverse health effects. This study aimed to assess the knowledge, attitudes, and practices toward using plastic for food and drinks among a sample of the Egyptian population.Materials and methodsA questionnaire was designed based on scientific literature to assess sociodemographic data, knowledge, attitudes, and practices toward the use of plastic for food and drinks. A total of 639 participants were recruited by employing the convenience sampling technique.ResultsMore than half of the participants (347, 54%) had poor knowledge scores. Personal experiences, social media, and web pages represented the most common knowledge sources. A comparison between plastic-related knowledge scores and the studied sociodemographic characteristics revealed statistically significant differences in age, gender, education, marital status, residence, working, and socioeconomic standard. A good attitude was reported by the majority (515, 80.6%) of participants. The majority (493, 77.2%) were occasional and frequent plastic users and the practice scores were significantly associated with age, education, residence, and socioeconomic standard. Higher educational level, gender (women), and rural residence were predictors of good participants knowledge, while lower socioeconomic status and urban residence were predictors of bad participants practice in a multivariate logistic regression analysis.ConclusionThe observed unsatisfactory knowledge and practice scores vs. the high attitude indicates a knowledge gap that can help direct future improvements. We call for public awareness programs about safe plastic use and the related health hazards of plastic chemicals. We also stress upon the urgent need for a collaboration between health authorities and the plastic and food industry to guarantee that information about proper plastic use is conveyed to consumers
Hepatitis-c virus infection and exposure to blood and body fluids among nurses and paramedical personnel at the Alexandria University Hospitals, Egypt
Background: Worldwide, prevalence of anti-HCV positivity in health care workers (HCWs) ranges from 0% to 9.7%. The current study was conducted to calculate prevalence of HCV infection, frequency and characteristics of blood and body fluid (BBF) exposure among HCW at the Alexandria University Hospitals.Methods: Hospital-based cross-sectional approach was adopted. At the Hospitals, 62.2% of available nurses and paramedical personnel voluntarily participated (n = 499), and were interviewed, screened for HCV antibodies. Quantitative estimation of HCV-RNA was done to seropositive cases.Results: Prevalence of anti-HCV antibodies and HCV infection was 8.6%, and 4.4% respectively. The frequency of BBF exposures was 66.7%. Blood/blood products were mainly involved (92.1%). More than half of exposed HCWs reported not wearing personal protective devices. Anatomical site of exposure was mainly right hand palm (36.2%). Regarding needle-stick injuries, two thirds of injured HCWs were the original user of sharp item which was contaminated in 79.7% of injuries. In 70.2% of injuries, disposable syringes were involved and occurred during item disposal. About 61% of injuries were superficial.Conclusion: Prevalence of HCV infection among HCWs is similar to that among general population in the country. Nurses and housekeepers are frequently exposed to BBF. Adherence to infection control measures according to the National Guidelines is crucial to reduce HCV transmission.Keywords: Hepatitis C, Infection, Needlestick injuries, Nurses, Paramedical personne
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